-
1
-
-
22844432020
-
A chromatin-associated and transcriptionally inactive p53-MDM2 complex occurs in mdm2 SNP309 homozygous cells
-
Arva NC, Gopen TR, Talbott KE, Campbell LE, Chicas A, White DE, Bond GL, Levine AJ, Bargonetti J. A chromatin-associated and transcriptionally inactive p53-MDM2 complex occurs in mdm2 SNP309 homozygous cells. J Biol Chem 2005;29:26776-26787.
-
(2005)
J Biol Chem
, vol.29
, pp. 26776-26787
-
-
Arva, N.C.1
Gopen, T.R.2
Talbott, K.E.3
Campbell, L.E.4
Chicas, A.5
White, D.E.6
Bond, G.L.7
Levine, A.J.8
Bargonetti, J.9
-
2
-
-
8844278362
-
A single nucleotide polymorphism in the MDM2 promoter attenuates the p53 tumor suppressor pathway and accelerates tumor formation in humans
-
Bond GL, Hu W, Bond EE, Robins H, Lutzker SG, Srva NC, Bargonetti J, Bartel F, Taubert H, Wuerl P et al. A single nucleotide polymorphism in the MDM2 promoter attenuates the p53 tumor suppressor pathway and accelerates tumor formation in humans. Cell 2004;119:591-602.
-
(2004)
Cell
, vol.119
, pp. 591-602
-
-
Bond, G.L.1
Hu, W.2
Bond, E.E.3
Robins, H.4
Lutzker, S.G.5
Srva, N.C.6
Bargonetti, J.7
Bartel, F.8
Taubert, H.9
Wuerl, P.10
-
3
-
-
0032080297
-
The human oncoprotein MDM2 arrests the cell cycle: Elimination of its cell-cycle-inhibitory function induces tumorigenesis
-
Brown DR, Thomas CA, Deb SP. The human oncoprotein MDM2 arrests the cell cycle: elimination of its cell-cycle-inhibitory function induces tumorigenesis. EMBO J 1998;17:2513-2525.
-
(1998)
EMBO J
, vol.17
, pp. 2513-2525
-
-
Brown, D.R.1
Thomas, C.A.2
Deb, S.P.3
-
4
-
-
16444380911
-
Activation of p53 by MDM2 antagonists can protect proliferating cells from mitotic inhibitors
-
Carvajal D, Tovar C, Yang H, Vu BT, Heimbrook DC, Vassilev LT. Activation of p53 by MDM2 antagonists can protect proliferating cells from mitotic inhibitors. Cancer Res 2005;65:1918-1924.
-
(2005)
Cancer Res
, vol.65
, pp. 1918-1924
-
-
Carvajal, D.1
Tovar, C.2
Yang, H.3
Vu, B.T.4
Heimbrook, D.C.5
Vassilev, L.T.6
-
5
-
-
0043269927
-
Expression of angiogenesis- and apoptosis-related genes in chorionic villi derived from recurrent pregnancy loss patients
-
Choi HK, Choi BC, Lee SH, Kin JW, Cha KY, Baek KH. Expression of angiogenesis- and apoptosis-related genes in chorionic villi derived from recurrent pregnancy loss patients. Mol Reprod Dev 2003;1:24-31.
-
(2003)
Mol Reprod Dev
, vol.1
, pp. 24-31
-
-
Choi, H.K.1
Choi, B.C.2
Lee, S.H.3
Kin, J.W.4
Cha, K.Y.5
Baek, K.H.6
-
6
-
-
0028235122
-
An informative protocol for the investigation of recurrent miscarriage: Preliminary experience of 500 consecutive cases
-
Clifford K, Rai R, Watson H, Regan L. An informative protocol for the investigation of recurrent miscarriage: preliminary experience of 500 consecutive cases. Hum Reprod 1994;9:1328-1332.
-
(1994)
Hum Reprod
, vol.9
, pp. 1328-1332
-
-
Clifford, K.1
Rai, R.2
Watson, H.3
Regan, L.4
-
7
-
-
0029590161
-
MDM2 transformation in the absence of p53 and abrogation of the p 107 G1 cell-cycle arrest
-
Dubs-Poterszman MC, Tocque B, Wasylyk B. MDM2 transformation in the absence of p53 and abrogation of the p 107 G1 cell-cycle arrest. Oncogene 1995;11:2445-2449.
-
(1995)
Oncogene
, vol.11
, pp. 2445-2449
-
-
Dubs-Poterszman, M.C.1
Tocque, B.2
Wasylyk, B.3
-
8
-
-
0025853776
-
Tumorigenic potential associated with enhanced expression of a gene that is amplified in a mouse tumor cell line
-
Fakharzadeh SS, Trusko SP, George DL. Tumorigenic potential associated with enhanced expression of a gene that is amplified in a mouse tumor cell line. EMBO J 1991;10:1565-1569.
-
(1991)
EMBO J
, vol.10
, pp. 1565-1569
-
-
Fakharzadeh, S.S.1
Trusko, S.P.2
George, D.L.3
-
10
-
-
0033815931
-
Placental apoptosis in normal and abnormal pregnancies
-
Halperine R, Peller S, Rotschild M, Bukvsky I, Schneider D. Placental apoptosis in normal and abnormal pregnancies. Gynecol Obstet Invest 2000;50:84-87.
-
(2000)
Gynecol Obstet Invest
, vol.50
, pp. 84-87
-
-
Halperine, R.1
Peller, S.2
Rotschild, M.3
Bukvsky, I.4
Schneider, D.5
-
11
-
-
0027945531
-
Recurrent miscarriage: Epidemiologic factors, definitions, and incidence
-
Hatasaka HH. Recurrent miscarriage: epidemiologic factors, definitions, and incidence. Clin Obstet Gynecol 1994;37:625-634.
-
(1994)
Clin Obstet Gynecol
, vol.37
, pp. 625-634
-
-
Hatasaka, H.H.1
-
12
-
-
27144529920
-
The role of p53 and MDM2 polymorphisms in the risk of esophageal squamous cell carcinoma
-
Hong Y, Miao X, Zhang X, Ding F, Luo A, Guo Y, Tan W, Liu Z, Lin D. The role of p53 and MDM2 polymorphisms in the risk of esophageal squamous cell carcinoma. Cancer Res 2005;65:9582-9587.
-
(2005)
Cancer Res
, vol.65
, pp. 9582-9587
-
-
Hong, Y.1
Miao, X.2
Zhang, X.3
Ding, F.4
Luo, A.5
Guo, Y.6
Tan, W.7
Liu, Z.8
Lin, D.9
-
13
-
-
0037049907
-
Apoptosis in the first trimester human placenta: The role in maintaining immune privilege at the maternal-foetal interface and in the trophoblast remodeling
-
Jerzak M, Bischof P. Apoptosis in the first trimester human placenta: the role in maintaining immune privilege at the maternal-foetal interface and in the trophoblast remodeling. Eur J Obstet Gynecol Reprod Biol 2002;100:138-142.
-
(2002)
Eur J Obstet Gynecol Reprod Biol
, vol.100
, pp. 138-142
-
-
Jerzak, M.1
Bischof, P.2
-
14
-
-
0032417695
-
Overexpression of Mdm2 in mice reveals a p53-independent role for Mdm2 in tumorigenesis
-
Jones SN, Hancock AR, Vogel H, Donehower LA, Bradley A. Overexpression of Mdm2 in mice reveals a p53-independent role for Mdm2 in tumorigenesis. Proc Natl Acad Sci USA 1998;95: 15608-15612.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 15608-15612
-
-
Jones, S.N.1
Hancock, A.R.2
Vogel, H.3
Donehower, L.A.4
Bradley, A.5
-
15
-
-
33846703114
-
Nutlin3 blocks vascular endothelial growth factor induction by preventing the interaction between hypoxia inducible factor 1 a and Hdm2
-
LaRusch GA, Jackson MW, Dunbar JD, Warren RS, Donner DB, Mayo LD. Nutlin3 blocks vascular endothelial growth factor induction by preventing the interaction between hypoxia inducible factor 1 a and Hdm2. Cancer Res 2007;67:450-454.
-
(2007)
Cancer Res
, vol.67
, pp. 450-454
-
-
LaRusch, G.A.1
Jackson, M.W.2
Dunbar, J.D.3
Warren, R.S.4
Donner, D.B.5
Mayo, L.D.6
-
16
-
-
0033954382
-
To be, or not to be, that is the question. Apoptosis in human trophoblast
-
Levy R, Nelson DM. To be, or not to be, that is the question. Apoptosis in human trophoblast. Placenta 2000;21:1-13.
-
(2000)
Placenta
, vol.21
, pp. 1-13
-
-
Levy, R.1
Nelson, D.M.2
-
17
-
-
33749040649
-
MDM2 promoter polymorphism is associated with both an increased susceptibility to gastric carcinoma and poor prognosis
-
Ohmiya N, Taguchi A, Mabuchi N, Itoh A, Hirooka Y, Niwa Y, Goto H. MDM2 promoter polymorphism is associated with both an increased susceptibility to gastric carcinoma and poor prognosis. J Clin Oncol 2006;24:4434- 4440.
-
(2006)
J Clin Oncol
, vol.24
, pp. 4434-4440
-
-
Ohmiya, N.1
Taguchi, A.2
Mabuchi, N.3
Itoh, A.4
Hirooka, Y.5
Niwa, Y.6
Goto, H.7
-
18
-
-
0141958076
-
Angiopoietin-2 polymorphism in women with idiopathic recurrent miscarriage
-
Pietrowski D, Tempfer C, Bettendorf H, Burkle B, Nagele F, Unfried G, Keck C. Angiopoietin-2 polymorphism in women with idiopathic recurrent miscarriage. Fertil Steril 2003;4:1026-1029.
-
(2003)
Fertil Steril
, vol.4
, pp. 1026-1029
-
-
Pietrowski, D.1
Tempfer, C.2
Bettendorf, H.3
Burkle, B.4
Nagele, F.5
Unfried, G.6
Keck, C.7
-
19
-
-
18744366392
-
Recurrent pregnancy failure is associated with a polymorphism in the p53 tumor suppressor gene
-
Pietrowski D, Bettendorf H, Riener EK, Keck C, Hefler LA, Huber JC, Tempfer C. Recurrent pregnancy failure is associated with a polymorphism in the p53 tumor suppressor gene. Hum Reprod 2005; 4:848-851.
-
(2005)
Hum Reprod
, vol.4
, pp. 848-851
-
-
Pietrowski, D.1
Bettendorf, H.2
Riener, E.K.3
Keck, C.4
Hefler, L.A.5
Huber, J.C.6
Tempfer, C.7
-
20
-
-
0031746540
-
Oncogene and tumour suppressor gene products during trophoblast differentiation in the first trimester
-
Quenby S, Brazeau C, Drakeley A, Lewis-Jones DI, Vince G. Oncogene and tumour suppressor gene products during trophoblast differentiation in the first trimester. Mol Hum Reprod 1998;4:477-481.
-
(1998)
Mol Hum Reprod
, vol.4
, pp. 477-481
-
-
Quenby, S.1
Brazeau, C.2
Drakeley, A.3
Lewis-Jones, D.I.4
Vince, G.5
-
21
-
-
0033954247
-
Regulation of tumor angiogenesis by p53-induced degradation of hypoxia-inducible factor 1 alpha
-
Ravi R, Mookerjee B, Bhujwalla ZM, Sutter CH, Artemov D, Zeng Q, Dillehay LE, Madan A, Semenza GL, Bedi A. Regulation of tumor angiogenesis by p53-induced degradation of hypoxia-inducible factor 1 alpha. Genes Dev 2000;14:34-44.
-
(2000)
Genes Dev
, vol.14
, pp. 34-44
-
-
Ravi, R.1
Mookerjee, B.2
Bhujwalla, Z.M.3
Sutter, C.H.4
Artemov, D.5
Zeng, Q.6
Dillehay, L.E.7
Madan, A.8
Semenza, G.L.9
Bedi, A.10
-
22
-
-
0034644506
-
Opposing effects of Ras on p53: Transcriptional activation of mdm2 and induction of p 19ARF
-
Ries S, Biederer C, Woods D, Shifman O, Shirasawa S, Sasa-zuki T, McMahon M, McCormick F. Opposing effects of Ras on p53: transcriptional activation of mdm2 and induction of p 19ARF. Cell 2000;103:321-330.
-
(2000)
Cell
, vol.103
, pp. 321-330
-
-
Ries, S.1
Biederer, C.2
Woods, D.3
Shifman, O.4
Shirasawa, S.5
Sasa-zuki, T.6
McMahon, M.7
McCormick, F.8
-
23
-
-
0036097505
-
Apoptosis in the uterus of mice with pregnancy loss
-
Savion S, Lepsky E, Orenstein H, Carp H, Shepshelovich J, Torchinsky A, Fein A, Toder V. Apoptosis in the uterus of mice with pregnancy loss. Am J Reprod Immunol 2002;47:118-127.
-
(2002)
Am J Reprod Immunol
, vol.47
, pp. 118-127
-
-
Savion, S.1
Lepsky, E.2
Orenstein, H.3
Carp, H.4
Shepshelovich, J.5
Torchinsky, A.6
Fein, A.7
Toder, V.8
-
24
-
-
0035940463
-
p53 is a potential mediator of pregnancy and hormone-induced resistance to mammary carcinogenesis
-
Sivaraman L, Conneely OM, Medina D, O'Malley BW. p53 is a potential mediator of pregnancy and hormone-induced resistance to mammary carcinogenesis. Proc Natl Acad Sci USA 2001;98:12379-12384.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 12379-12384
-
-
Sivaraman, L.1
Conneely, O.M.2
Medina, D.3
O'Malley, B.W.4
-
25
-
-
34447098700
-
MDM2 and MDM4: P53 regulators as targets in anticancer therapy
-
Toledo F, Wahl GM. MDM2 and MDM4: p53 regulators as targets in anticancer therapy. Int J Biochem Cell Biol 2007;39:1476-1482.
-
(2007)
Int J Biochem Cell Biol
, vol.39
, pp. 1476-1482
-
-
Toledo, F.1
Wahl, G.M.2
-
26
-
-
0036406862
-
Mechanisms of 5-azacytidine (5Azc)-induced toxicity in the rat foetal brain
-
Ueno M, Katayama K, Nakayama H, Doi K. Mechanisms of 5-azacytidine (5Azc)-induced toxicity in the rat foetal brain. Int J Exp Pathol 2002; 83:139-150.
-
(2002)
Int J Exp Pathol
, vol.83
, pp. 139-150
-
-
Ueno, M.1
Katayama, K.2
Nakayama, H.3
Doi, K.4
-
27
-
-
84961014776
-
Spontaneous abortion risks in man: Data from reproductive histories collected in a medical genetics unit
-
Warburton D, Fraser FC. Spontaneous abortion risks in man: data from reproductive histories collected in a medical genetics unit. Am J Hum Genet 1964;16:1-25.
-
(1964)
Am J Hum Genet
, vol.16
, pp. 1-25
-
-
Warburton, D.1
Fraser, F.C.2
-
29
-
-
27144529920
-
The role of p53 and MDM2 polymorphisms in the risk of esophageal squamous cell carcinoma
-
Yuan H, Xiaoping M, Xuemei ZH, Fang D, Aiping L, Yongli G, Wen T, Zhihua L, Dongxin L. The role of p53 and MDM2 polymorphisms in the risk of esophageal squamous cell carcinoma. Cancer Res 2005; 65:9582-9587.
-
(2005)
Cancer Res
, vol.65
, pp. 9582-9587
-
-
Yuan, H.1
Xiaoping, M.2
Xuemei, Z.H.3
Fang, D.4
Aiping, L.5
Yongli, G.6
Wen, T.7
Zhihua, L.8
Dongxin, L.9
-
30
-
-
0029131447
-
A functional p53-responsive intronic promoter is contained within the human mdm2 gene
-
Zauberman A, Flusberg D, Haupt Y, Barak Y, Oren M. A functional p53-responsive intronic promoter is contained within the human mdm2 gene. Nucleic Acids Res 1995;23:2584-2592.
-
(1995)
Nucleic Acids Res
, vol.23
, pp. 2584-2592
-
-
Zauberman, A.1
Flusberg, D.2
Haupt, Y.3
Barak, Y.4
Oren, M.5
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