A chromatin-associated and transcriptionally inactive p53-Mdm2 complex occurs in mdm2 SNP309 homozygous cells

Journal of Biological Chemistry

Volumn 280, Issue 29, 2005, Pages 26776-26787

  Arva, Nicoleta C ^a   Gopen, Tamara R ^a   Talbott, Kathryn E ^a   Campbell, Latoya E ^a   Chicas, Agustin ^a   White, David E ^a   Bond, Gareth L ^b   Levine, Arnold J ^b   Bargonetti, Jill ^a,c  

^a CITY UNIVERSITY OF NEW YORK   (United States)

^b RUTGERS CANCER INSTITUTE OF NEW JERSEY   (United States)

^c CITY UNIVERSITY OF NEW YORK   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; DNA; GENES; PROTEINS; RNA; TUMORS;

ENDOGENOUS TARGET GENES; NUCLEAR ACCUMULATION; SINGLE NUCLEOTIDE POLYMORPHISM (SNP); TRANSCRIPTIONAL ACTIVATION;

CELLS;

CAMPTOTHECIN; ETOPOSIDE; MITOMYCIN C; PROTEIN P53; SERINE; SMALL INTERFERING RNA;

ARTICLE; CANCER CELL; CHROMATIN; COMPLEX FORMATION; CONTROLLED STUDY; GENE OVEREXPRESSION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; MDM2 GENE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DNA BINDING; PROTEIN PHOSPHORYLATION; SINGLE NUCLEOTIDE POLYMORPHISM; TRANSCRIPTION INITIATION; TUMOR SUPPRESSOR GENE;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CHROMATIN; HOMOZYGOTE; HUMANS; NUCLEAR PROTEINS; PHOSPHORYLATION; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEIN BINDING; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-MDM2; TRANS-ACTIVATION (GENETICS); TUMOR SUPPRESSOR PROTEIN P53;

EID: 22844432020     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M505203200     Document Type: Article

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