Vascular endothelial growth factor-C siRNA delivered via calcium carbonate nanoparticle effectively inhibits lymphangiogenesis and growth of colorectal cancer in vivo

Cancer Biotherapy and Radiopharmaceuticals

Volumn 24, Issue 2, 2009, Pages 249-259

  He, Xiao Wen ^a   Liu, Ting ^b   Xiao, Yu ^a   Feng, Ya Ling ^c   Cheng, Dao Jin ^a   Tingting, Guo ^d   Zhang, Yi ^a   Chen, Yu Xiang ^d   Zhang, Liyuan ^d  

^a SHAOXING PEOPLE S HOSPITAL   (China)

^b CENTRAL SOUTH UNIVERSITY   (China)

^c THE THIRD XIANGYA HOSPITAL OF CENTRAL SOUTH UNIVERSITY   (China)

^d CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

CaCO3 nanoparticles; Colorectal cancer; Nonviral vector; RNA interference; Vascular endothelial growth factor C

Indexed keywords

CALCIUM CARBONATE; MESSENGER RNA; SMALL INTERFERING RNA; VASCULOTROPIN C;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER GENE THERAPY; CANCER INHIBITION; COLORECTAL CANCER; COMPARATIVE STUDY; CONTROLLED STUDY; CYTOTOXICITY; DOWN REGULATION; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IN VIVO STUDY; LYMPH NODE METASTASIS; LYMPHANGIOGENESIS; MALE; MOUSE; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; NONVIRAL GENE THERAPY; PARTICLE SIZE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; SURFACE CHARGE; XENOGRAFT;

ANIMALS; CALCIUM CARBONATE; CELL LINE, TUMOR; COLORECTAL NEOPLASMS; DNA, PLANT; GENE THERAPY; HUMANS; LYMPHANGIOGENESIS; MALE; MICE; MICE, INBRED BALB C; MICE, NUDE; NANOPARTICLES; NEOVASCULARIZATION, PATHOLOGIC; PLASMIDS; RNA, SMALL INTERFERING; TRANSFECTION; VASCULAR ENDOTHELIAL GROWTH FACTOR C; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 66249094537     PISSN: 10849785     EISSN: None     Source Type: Journal    
DOI: 10.1089/cbr.2008.0515     Document Type: Article

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