Role of the perforin/granzyme cell death pathway in D-Gal/LPS-induced inflammatory liver injury

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 296, Issue 5, 2009, Pages

  Kuhla, Angela ^a   Eipel, Christian ^a   Abshagen, Kerstin ^a   Siebert, Nikolai ^a   Menger, Michael D ^b   Vollmar, Brigitte ^a  

^a UNIVERSITY OF ROSTOCK   (Germany)

^b SAARLAND UNIVERSITY   (Germany)

Author keywords

Apoptosis; Caspase 3; Immunoregulation; Interleukin 6; Necrapoptosis; Tumor necrosis factor

Indexed keywords

AMINOTRANSFERASE; GALACTOSAMINE; GRANZYME; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; PERFORIN; TUMOR NECROSIS FACTOR ALPHA; IMMUNOGLOBULIN G; MESSENGER RNA; NONSTEROID ANTIINFLAMMATORY AGENT; PERFORIN, MOUSE; PORE FORMING CYTOTOXIC PROTEIN; TNFR FC FUSION PROTEIN; TNFR-FC FUSION PROTEIN; TUMOR NECROSIS FACTOR RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVITY; ENZYME RELEASE; IMMUNOREGULATION; KNOCKOUT MOUSE; LIVER FAILURE; LIVER INJURY; LIVER NECROSIS; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; ANIMAL; BLOOD; C57BL MOUSE; CHEMICALLY INDUCED DISORDER; CYTOTOXIC T LYMPHOCYTE; DISEASE MODEL; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; GENETICS; IMMUNOLOGY; LIVER; METABOLISM; MOUSE MUTANT; NECROSIS; PATHOLOGY; SIGNAL TRANSDUCTION; TIME; TOXIC HEPATITIS;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; APOPTOSIS; DISEASE MODELS, ANIMAL; GALACTOSAMINE; GRANZYMES; HEPATITIS, TOXIC; IMMUNOGLOBULIN G; INTERLEUKIN-6; LIPOPOLYSACCHARIDES; LIVER; LIVER FAILURE, ACUTE; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NECROSIS; PORE FORMING CYTOTOXIC PROTEINS; RECEPTORS, TUMOR NECROSIS FACTOR; RNA, MESSENGER; SIGNAL TRANSDUCTION; T-LYMPHOCYTES, CYTOTOXIC; TIME FACTORS; TRANSAMINASES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 66149143906     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.90689.2008     Document Type: Article

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