3D-QSAR studies on DATAs and DAPYs for HIV-RT inhibitors using CoMFA and CoMSIA approaches

QSAR and Combinatorial Science

Volumn 28, Issue 2, 2009, Pages 218-225

  Park, Hyung Yeon ^a   Ju, Sun Mi ^a   Lee, Do Young ^a   Zhang, Hui ^a   Kim, Chan Kyung ^a  

^a Inha University   (South Korea)

Author keywords

CoMFA; CoMSIA; Contour maps; Human immunodeficiency virus reverse transcriptase; Structure based QSAR

Indexed keywords

COMPUTATIONAL CHEMISTRY; DISEASES; MOLECULAR GRAPHICS; VIRUSES;

ANALYSIS APPROACH; COMPARATIVE MOLECULAR FIELD ANALYSIS; COMPARATIVE-MOLECULAR-SIMILARITY-INDICES ANALYSIS; CONTOUR MAP; HUMAN IMMUNODEFICIENCY VIRUS-REVERSE TRANSCRIPTASE; QUANTITATIVE STRUCTURE ACTIVITY RELATIONSHIP; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP STUDIES; STRUCTURE-BASED; STRUCTURE-BASED QUANTITATIVE STRUCTURE -ACTIVITY RELATIONSHIP; X-RAY STRUCTURE;

ENZYMES;

DAPIVIRINE; DIARYLPYRIMIDINE DERIVATIVE; DIARYLTRIAZINE DERIVATIVE; RNA DIRECTED DNA POLYMERASE INHIBITOR; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; COMPARATIVE MOLECULAR FIELD ANALYSIS; COMPARATIVE MOLECULAR SIMILARITY INDICES ANALYSIS; CONTROLLED STUDY; DRUG DESIGN; DRUG STRUCTURE; HUMAN; HUMAN CELL; PRIORITY JOURNAL; QUANTITATIVE STRUCTURE ACTIVITY RELATION; THREE DIMENSIONAL IMAGING;

HUMAN IMMUNODEFICIENCY VIRUS;

EID: 66149129991     PISSN: 1611020X     EISSN: 16110218     Source Type: Journal    
DOI: 10.1002/qsar.200710135     Document Type: Article

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