To learn, you must pay attention. Molecular insights into teachers' wisdom

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 18, 2009, Pages 7267-7268

  Caron, Marc G ^a   Wightman, R Mark ^b  

^a DUKE UNIVERSITY   (United States)

^b University of North Carolina at Chapel Hill   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COCAINE; DOPAMINE; DOPAMINE TRANSPORTER; MORPHINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 1; NEUROTRANSMITTER; PSYCHOSTIMULANT AGENT; NR1 NMDA RECEPTOR;

ANIMAL EXPERIMENT; BEHAVIOR; BRAIN FUNCTION; COGNITION; CONTROLLED STUDY; DOPAMINE RELEASE; DOPAMINERGIC NERVE CELL; DOPAMINERGIC TRANSMISSION; ELECTROPHYSIOLOGY; EMOTIONALITY; ENVIRONMENT; EVOKED RESPONSE; FOOD INTAKE; LEARNING; LOCOMOTION; MOUSE; NEUROCHEMISTRY; NEUROPSYCHOLOGICAL TEST; NEUROTRANSMISSION; NONHUMAN; NOTE; PRIORITY JOURNAL; REWARD; SENSITIZATION; SENSORIMOTOR FUNCTION; SIGNAL TRANSDUCTION; SOCIAL INTERACTION; STRESS; SYNAPTIC TRANSMISSION; TASK PERFORMANCE; WORKING MEMORY; ANIMAL; ARTICLE; ATTENTION; ATTENTION DEFICIT DISORDER; BRAIN; GENETICS; HUMAN; METABOLISM; MOUSE MUTANT; PATHOPHYSIOLOGY; PHYSIOLOGY;

ANIMALS; ATTENTION; ATTENTION DEFICIT DISORDER WITH HYPERACTIVITY; BRAIN; DOPAMINE; HUMANS; LEARNING; MICE; MICE, KNOCKOUT; RECEPTORS, N-METHYL-D-ASPARTATE; REWARD;

EID: 66149112575     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0903306106     Document Type: Note

References (12)

1. Haber SN, Fudge JL, McFarland NR (2000) Striatonigros- triatal pathways in primates form an ascending spiral from the shell to the dorsolateral striatum. J Neurosci 20:2369-2382.
2. Grace AA (1991) Phasic versus tonic dopamine release and the modulation of dopamine system responsivity: A hypothesis for the etiology of schizophrenia. Neuro- science 41:1-24.
3. Schultz W (2007) Behavioral dopamine signals. Trends Neurosci 30:203-210.
4. Sombers LA, Beyene M, Carelli RM, Wightman RM (2009) Synaptic overflow of dopamine in the nucleus accumbensarisesfrom neuronal activityin the ventral tegmental area. J Neurosci 29:1735-1742.
5. Zweifel LS, et al. (2009) Disruption of NMDAR- dependent burst firing by dopamine neurons provides selective assessment of phasic dopamine- dependent behavior. Proc Natl Acad Sci USA 106:7281-7288.
6. Cagniard B,etal. (2006)Dopaminescalesperformance in the absence of new learning. Neuron 51:541-547.
7. Hnasko TS, Sotak BN, Palmiter RD (2007) Cocaine- conditioned place preference by dopamine-deficient mice is mediated by serotonin. J Neurosci 27:12484-12488.
8. Zweifel LS, Argilli E, Bonci A, Palmiter RD (2008) Role of NMDA receptors in dopamine neurons for plasticity and addictive behaviors. Neuron 59:486-496.
9. Engblom D,etal. (2008)Glutamatereceptorson dopa- mine neurons control the persistence of cocaine seeking. Neuron 59:497-508.
10. Overton P, Clark D (1992) lontophoretically administered drugs acting atthe N-methyl-D-aspartate receptor modulate burst firing in A9 dopamine neurons in the rat. Synapse 10:131-140.
11. Ungless MA, Magill PJ, Bolam JP (2004) Uniform inhibition of dopamine neurons in the ventral teg- mental area by aversive stimuli. Science 303:2040-2042.
12. Wightman RM, Robinson DL (2002) Transientchanges in mesolimbic dopamine and their association with 'reward.' J Neurochem 82:721-735.