De novo sequence determination of modified oligonucleotides

Analytical Chemistry

Volumn 81, Issue 10, 2009, Pages 3723-3730

  Farand, Julie ^a   Gosselin, Francis ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL DEGRADATION; CHEMICAL SEQUENCING; CHEMICALLY MODIFIED; COMPOSITION ANALYSIS; ENZYMATIC DIGESTIONS; MODIFIED OLIGONUCLEOTIDES; RANDOM MIXTURES; RIBONUCLEOTIDES; SHORT INTERFERING RNA; TIME OF FLIGHT; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY;

BIOMOLECULES; CHROMATOGRAPHIC ANALYSIS; DEGRADATION; ELECTROSPRAY IONIZATION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; WASTEWATER TREATMENT;

OLIGONUCLEOTIDES;

OLIGONUCLEOTIDE; RIBONUCLEOTIDE; SMALL INTERFERING RNA;

ARTICLE; CHEMICAL MODIFICATION; ELECTROSPRAY; LIQUID CHROMATOGRAPHY; SEQUENCE ANALYSIS; TANDEM MASS SPECTROMETRY; TIME OF FLIGHT MASS SPECTROMETRY;

BASE SEQUENCE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HYDROLYSIS; NUCLEOSIDES; NUCLEOTIDES; OLIGONUCLEOTIDES; RNA, SMALL INTERFERING; SEQUENCE ANALYSIS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TANDEM MASS SPECTROMETRY;

EID: 66149106298     PISSN: 00032700     EISSN: None     Source Type: Journal    
DOI: 10.1021/ac802452p     Document Type: Article

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