Fragmentation mechanisms of oligodeoxynucleotides studied by H/D exchange and electrospray ionization tandem mass spectrometry

Journal of the American Society for Mass Spectrometry

Volumn 12, Issue 2, 2001, Pages 193-205

  Wan, Katty X ^a   Gross, Julia ^b   Hillenkamp, Franz ^b   Gross, Michael L ^a  

^a WASHINGTON UNIVERSITY   (United States)

^b UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

DECOMPOSITION; DNA; HYDROGEN; MASS SPECTROMETERS; MASS SPECTROMETRY; MUTAGENESIS; ULTRAVIOLET RADIATION;

FRAGMENTATION;

ORGANIC POLYMERS;

DEUTERIUM; HYDROGEN; OLIGODEOXYNUCLEOTIDE;

MASS SPECTROMETRY;

ARTICLE; CONTROLLED STUDY; DECOMPOSITION; DNA DAMAGE; ELECTRIC POTENTIAL; ENERGY; IONIZATION; MASS SPECTROMETRY; MUTATION RATE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRECURSOR; TANDEM MASS SPECTROMETRY; ULTRAVIOLET RADIATION;

DEUTERIUM; HYDROGEN; OLIGONUCLEOTIDES; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 0035561180     PISSN: 10440305     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1044-0305(00)00208-7     Document Type: Article

References (14)

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6. Mass and sequence verification of modified oligonucleotides using electrospray tandem mass spectrometry
7. Mechanisms and uses of hydrogen exchange
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9. Enhanced gas-phase hydrogen-deuterium exchange of oligonucleotide and protein ions stored in an external multipole ion reservoir
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11. Investigations of the metastable decay of DNA under ultraviolet matrix-assisted laser desorption/ionization conditions with post-source-decay analysis and hydrogen/deuterium exchange
12. Tandem mass spectrometry of small, multiply charged oligonucleotides
13. Direct mass spectrometric sequencing of low-picomole amounts of oligodeoxynucleotides with up to 21 bases by matrix-assisted laser desorption/ionization mass spectrometry
14. 7-Deaza purine bases offer a higher ion stability in the analysis of DNA by matrix-assisted laser desorption/ionization mass spectrometry