High-resolution x-ray structure of human aquaporin 5

Proceedings of the National Academy of Sciences of the United States of America

Volumn 105, Issue 36, 2008, Pages 13327-13332

  Horsefield, Rob ^a   Nordén, Kristina ^b   Fellert, Maria ^b   Backmark, Anna ^c   Törnroth Horsefield, Susanna ^a   Terwisscha Van Scheltinga, Anke C ^d   Kvassman, Jan ^e   Kjellbom, Per ^b   Johanson, Urban ^b   Neutze, Richard ^a  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

^b LUND UNIVERSITY   (Sweden)

^c CHALMERS UNIVERSITY OF TECHNOLOGY   (Sweden)

^d MAX PLANCK INSTITUTE OF BIOPHYSICS   (Germany)

^e LINNAEUS UNIVERSITY   (Sweden)

Author keywords

Crystallography; Heterologous overexpression; Membrane protein; Trafficking; Water channel protein

Indexed keywords

AQUAPORIN 5; ION; LIPID; TETRAMER;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CONFORMATIONAL TRANSITION; CONSENSUS; GAS; OPTICAL RESOLUTION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN STRUCTURE; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; STRUCTURE ANALYSIS; X RAY CRYSTALLOGRAPHY;

AQUAPORIN 5; CRYSTALLIZATION; CRYSTALLOGRAPHY, X-RAY; HUMANS; LIPIDS; MODELS, MOLECULAR; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, TERTIARY; STRUCTURAL HOMOLOGY, PROTEIN;

EUKARYOTA;

EID: 51649115305     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0801466105     Document Type: Article

References (49)

1. Preston GM, Carroll TP, Guggino WB, Agre P (1992) Appearance of water channels in Xenopus oocytes expressing red cell CHIP28 protein. Science 256:385-387.
2. King LS, Kozono D, Agre P (2004) From structure to disease: The evolving tale of aquaporin biology. Nat Rev Mol Cell Biol 5:687-698.
3. Krane CM, Goldstein DL (2007) Comparative functional analysis of aquaporins/glyceroporins in mammals and anurans. Mamm Genome 18:452-462.
4. Gonen T, Sliz P, Kistler J, Cheng Y, Walz T (2004) Aquaporin-0 membrane junctions reveal the structure of a closed water pore. Nature 429:193-197.
5. Harries WE, Akhavan D, Miercke LJ, Khademi S, Stroud RM (2004) The channel architecture of aquaporin 0 at a 2.2 Å resolution. Proc Natl Acad Sci USA 101:14045-14050.
6. Gonen T, et al. (2005) Lipid-protein interactions in double-layered two-dimensional AQP0 crystals. Nature 438:633-638.
7. Murata K, et al. (2000) Structural determinants of water permeation through aquaporin-1. Nature 407:599-605.
8. Sui H, Han BG, Lee JK, Walian P, Jap BK (2001) Structural basis of water-specific transport through the AQP1 water channel. Nature 414:872-878.
9. Schenk AD, et al. (2005) The 4.5 A structure of human AQP2. J Mol Biol 350:278-289.
10. Hiroaki Y, et al. (2006) Implications of the aquaporin-4 structure on array formation and cell adhesion. J Mol Biol 355:628-639.
11. Kukulski W, et al. (2005) The 5 Å structure of heterologously expressed plant aquaporin SoPIP2;1. J Mol Biol 350:611-616.
12. Törnroth-Horsefield S, et al. (2006) Structural mechanism of plant aquaporin gating. Nature 439:688-694.
13. Savage DF, Egea PF, Robles-Colmenares Y, O'Connell JD, Stroud RM (2003) Architecture and selectivity in aquaporins: 2.5 Å X-ray structure of aquaporin Z. PLoS Biol 1:E72.
14. Jiang J, Daniels BV, Fu D (2006) Crystal structure of AqpZ tetramer reveals two distinct Arg-189 conformations associated with water permeation through the narrowest constriction of the water-conducting channel. J Biol Chem 281:454-460.
15. Fu D, et al. (2000) Structure of a glycerol-conducting channel and the basis for its selectivity. Science 290:481-486.
16. Lee JK, Kozono D, Remis J, Kitagawa Y, Agre P, Stroud RM (2005) Structural basis for conductance by the archaeal aquaporin AqpM at 1.68 A. Proc Natl Acad Sci USA 102:18932-18937.
17. Wang Y, Tajkhorshid E (2007) Molecular mechanisms of conduction and selectivity in aquaporin water channels. J Nutr 137:1509S-1515S.
18. de Groot BL, Grubmüller H (2005) The dynamics and energetics of water permeation and proton exclusion in aquaporins. Curr Opin Struct Biol 15:176-183.
19. Hedfalk K, et al. (2006) Aquaporin gating. Curr Opin Struct Biol 16:447-456.
20. Han Z, Patil RV (2000) Protein kinase A-dependent phosphorylation of aquaporin-1. Biochem Biophys Res Commun 273:328-332.
21. de Mattia F, et al. (2005) Lack of arginine vasopressin-induced phosphorylation of aquaporin-2 mutant AQP2-R254L explains dominant nephrogenic diabetes insipidus. J Am Soc Nephrol 16:2872-2880.
22. Yang F, Kawedia JD, Menon AG (2003) Cyclic AMP regulates aquaporin 5 expression at both transcriptional and post-transcriptional levels through a protein kinase A pathway. J Biol Chem 278:32173-32180.
23. Ishikawa Y, et al. (2005) Identification of AQP5 in lipid rafts and its translocation to apical membranes by activation of M3 mAChRs in interlobular ducts of rat parotid gland. Am J Physiol Cell Physiol 289:C1303-C1311.
24. Kosugi-Tanaka C, Li X, Yao C, Akamatsu T, Kanamori N, Hosoi K (2006) Protein kinase A-regulated membrane trafficking of a green fluorescent protein-aquaporin 5 chimera in MDCK cells. Biochim Biophys Acta 1763:337-344.
25. Garcia F, et al. (2001) The water channel aquaporin-8 is mainly intracellular in rat hepatocytes, and its plasma membrane insertion is stimulated by cyclic AMP. J Biol Chem 276:12147-12152.
26. Gunnarson E, et al. (2008) Identification of amolecular target for glutamate regulation of astrocyte water permeability. Glia 56:587-596.
27. Raina S, Preston GM, Guggino WB, Agre P (1995) Molecular cloning and characterization of an aquaporin cDNA from salivary, lacrimal, and respiratory tissues. J Biol Chem 270:1908-1912.
28. Wellner RB, Hong S, Cotrim AP, Swaim WD, Baum BJ (2005) Modifying the NH2 and COOH termini of aquaporin-5: Effects on localization in polarized epithelial cells. Tissue Eng 11:1449-1458.
29. Tsubota K, Hirai S, King LS, Agre P, Ishida N (2001) Defective cellular trafficking of lacrimal gland aquaporin-5 in Sjogren's syndrome. Lancet 357:688-689.
30. Terwisscha van Scheltinga AC, Valegard K, Hajdu J, Andersson I (2003) MIR phasing using merohedrally twinned crystals. Acta Crystallogr D Biol Crystallogr 59:2017-2022.
31. Smart OS, Goodfellow JM, Wallace BA (1993) The pore dimensions of gramicidin A. Biophys J 65:2455-2460.
32. Yool AJ, Stamer WD, Regan JW (1996) Forskolin stimulation of water and cation permeability in aquaporin 1 water channels. Science 273:1216-1218.
33. Anthony TL, et al. (2000) Cloned human aquaporin-1 is a cyclic GMP-gated ion channel. Mol Pharmacol 57:576-588.
34. Yu J, Yool AJ, Schulten K, Tajkhorshid E (2006) Mechanism of gating and ion conductivity of a possible tetrameric pore in aquaporin-1. Structure 14:1411-1423.
35. Prasad GV, Coury LA, Finn F, Zeidel ML (1998) Reconstituted aquaporin 1 water channels transport CO2 across membranes. J Biol Chem 273:33123-33126.
36. Wang Y, Cohen J, Boron WF, Schulten K, Tajkhorshid E (2007) Exploring gas permeability of cellular membranes and membrane channels with molecular dynamics. J Struct Biol 157:534-544.
37. Uehlein N, Lovisolo C, Siefritz F, Kaldenhoff R (2003) The tobacco aquaporin NtAQP1 is a membrane CO2 pore with physiological functions. Nature 425:734-737.
38. Fang X, Yang B, Matthay MA, Verkman AS (2002) Evidence against aquaporin-1-dependent CO2 permeability in lung and kidney. J Physiol 542:63-69.
39. 2 permeate through aquaporin-1? Biophys J 91:842-848.
40. Opekarova M, Tanner W (2003) Specific lipid requirements of membrane proteins-a putative bottleneck in heterologous expression. Biochim Biophys Acta 1610:11-22.
41. Fushimi K, Sasaki S, Marumo F (1997) Phosphorylation of serine 256 is required for cAMP-dependent regulatory exocytosis of the aquaporin-2 water channel. J Biol Chem 272:14800-14804.
42. Gustafson CE, et al. (1998) Vasopressin regulated trafficking of a green fluorescent protein-aquaporin 2 chimera in LLC-PK1 cells. Histochem Cell Biol 110:377-386.
43. Woo J, et al. (2008) Membrane trafficking of AQP5 and cAMP dependent phosphorylation in bronchial epithelium. Biochem Biophys Res Commun 366:321-327.
44. 2+ and apoplastic water potential. Plant Cell 8:1181-1191.
45. Woo J, et al. (2008) Overexpression of AQP5, a putative oncogene, promotes cell growth and transformation. Cancer Lett 264:54-62.
46. Leslie AGW (1992) Recent changes to the MOSFLM package for processing film and image plate data. Joint CCP4 and ESF-EAMCB Newsletter on Protein Crystallography 26.
47. Kabsch W (1993) Automatic processing of rotation diffraction data from crystals of initially unknown symmetry and cell constants. J Appl Cryst 26:785-800.
48. Emsley P, Cowtan K (2004) Coot: Model-building tools for molecular graphics. Acta Crystallogr D Biol Crystallogr 60:2126-2132.
49. Sheldrick GM (2008) A short history of SHELX. Acta Crystallogr A 64:112-122.