Influence of polycation molecular weight on poly(2-dimethylaminoethyl methacrylate)-mediated DNA delivery in vitro

Biomacromolecules

Volumn 10, Issue 5, 2009, Pages 1244-1252

  Layman, John M ^a   Ramirez, Sean M ^a   Green, Matthew D ^a   Long, Timothy E ^a  

^a VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING AFFINITIES; CELLULAR MEMBRANES; CELLULAR UPTAKE; COMPETITIVE BINDING; CONVENTIONAL FREE-RADICAL POLYMERIZATION; CRITICAL STEPS; DIMETHYLAMINOETHYL METHACRYLATES; DNA BINDING; DNA DELIVERY; ENDOSOMAL RELEASE; GEL SHIFT ASSAYS; HUMAN BRAIN; IN-VITRO; LDH ASSAY; NONVIRAL GENE THERAPY; PDMAEMA; PLASMID DNA; POLYCATION; POLYPLEX; POLYPLEXES; REPORTER-GENE EXPRESSION; STRUCTURE PROPERTY; TRANSFECTION EFFICIENCY; WEIGHT-AVERAGE MOLECULAR WEIGHT;

ASSAYS; BINDING ENERGY; CELL MEMBRANES; DNA; DRUG THERAPY; ENDOTHELIAL CELLS; GELATION; GENE EXPRESSION; GENETIC ENGINEERING; MOLECULAR WEIGHT; NUCLEIC ACIDS; POLYSACCHARIDES; TOXICITY; WEIGHING;

FREE RADICAL POLYMERIZATION;

HEPARIN; LACTATE DEHYDROGENASE; LUCIFERASE; PLASMID DNA; POLY[2 (DIMETHYLAMINO)ETHYL METHACRYLATE];

ARTICLE; CELL CULTURE; CELL VIABILITY; CONTROLLED STUDY; DNA BINDING; DNA TRANSFECTION; DRUG CYTOTOXICITY; DRUG SYNTHESIS; DRUG UPTAKE; ENDOTHELIUM CELL; FLOW CYTOMETRY; GEL MOBILITY SHIFT ASSAY; GEL PERMEATION CHROMATOGRAPHY; HUMAN; HUMAN CELL; LIGHT SCATTERING; MOLECULAR WEIGHT; NONVIRAL GENE DELIVERY SYSTEM; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTON NUCLEAR MAGNETIC RESONANCE; TRANSMISSION ELECTRON MICROSCOPY;

CATIONS; CELL SURVIVAL; DNA; ENDOTHELIAL CELLS; GENE TRANSFER TECHNIQUES; HUMANS; METHACRYLATES; MOLECULAR WEIGHT; PLASMIDS; POLYMERS; TRANSFECTION;

EID: 66149087710     PISSN: 15257797     EISSN: None     Source Type: Journal    
DOI: 10.1021/bm9000124     Document Type: Article

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