메뉴 건너뛰기




Volumn 48, Issue 17, 2009, Pages 3717-3729

Novel αD-conopeptides and their precursors identified by cDNA cloning define the D-conotoxin superfamily

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID SEQUENCE; CDNA CLONING; CDNA SEQUENCE; CONOPEPTIDES; CONOTOXIN; CONOTOXINS; HETERODIMER; HOMODIMER; NICOTINIC ACETYLCHOLINE RECEPTORS (NACHRS); PARTIAL SEQUENCES; PEPTIDE INHIBITORS; PHYLOGENETIC ANALYSIS; SIGNAL PEPTIDE;

EID: 66049155827     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi9000326     Document Type: Article
Times cited : (33)

References (77)
  • 1
    • 0242331757 scopus 로고    scopus 로고
    • Therapeutic potential of venom peptides
    • Lewis, R. J., and Garcia, M. L. (2003) Therapeutic potential of venom peptides. Nat. Rev. Drug Discov. 2, 790-802. (Pubitemid 37361811)
    • (2003) Nature Reviews Drug Discovery , vol.2 , Issue.10 , pp. 790-802
    • Lewis, R.J.1    Garcia, M.L.2
  • 2
    • 3042606237 scopus 로고    scopus 로고
    • α-Conotoxins as tools for the elucidation of structure and function of neuronal nicotinic acetylcholine receptor subtypes
    • DOI 10.1111/j.1432-1033.2004.04145.x
    • Nicke, A., Wonnacott, S., and Lewis, R. J. (2004) α-Conotoxins as tools for the elucidation of structure and function of neuronal nicotinic acetylcholine receptor subtypes. Eur. J. Biochem. 271, 2305-2319. (Pubitemid 38813562)
    • (2004) European Journal of Biochemistry , vol.271 , Issue.12 , pp. 2305-2319
    • Nicke, A.1    Wonnacott, S.2    Lewis, R.J.3
  • 3
    • 33747666931 scopus 로고    scopus 로고
    • Identification of a novel class of nicotinic receptor antagonists: Dimeric conotoxins VxXIIA, VxXIIB, and VxXIIC from Conus vexillum
    • DOI 10.1074/jbc.M603703200
    • Loughnan, M., Nicke, A., Jones, A., Schroeder, C. I., Nevin, S. T., Adams, D. J., Alewood, P. F., and Lewis, R. J. (2006) Identification of a novel class of nicotinic receptor antagonists: Dimeric conotoxins VxXIIA, VxXIIB, and VxXIIC from Conus vexillum. J. Biol. Chem. 281, 24745-24755. (Pubitemid 44274249)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.34 , pp. 24745-24755
    • Loughnan, M.1    Nicke, A.2    Jones, A.3    Schroeder, C.I.4    Nevin, S.T.5    Adams, D.J.6    Alewood, P.F.7    Lewis, R.J.8
  • 4
    • 34547637063 scopus 로고    scopus 로고
    • αC-conotoxin PrXA: A new family of nicotinic acetylcholine receptor antagonists
    • DOI 10.1021/bi700582m
    • Jimenez, E. C., Olivera, B. M., and Teichert, R. W. (2007) αC-Conotoxin PrXA: A new family of nicotinic acetylcholine receptor antagonists. Biochemistry 46, 8717-8724. (Pubitemid 47204437)
    • (2007) Biochemistry , vol.46 , Issue.30 , pp. 8717-8724
    • Jimenez, E.C.1    Olivera, B.M.2    Teichert, R.W.3
  • 6
    • 0347989461 scopus 로고    scopus 로고
    • Conus Venoms: A Rich Source of Novel Ion Channel-Targeted Peptides
    • DOI 10.1152/physrev.00020.2003
    • Terlau, H., and Olivera, B. M. (2004) Conus venoms: A rich source of novel ion channel-targeted peptides. Physiol. Rev. 84, 41-68. (Pubitemid 38049875)
    • (2004) Physiological Reviews , vol.84 , Issue.1 , pp. 41-68
    • Terlau, H.1    Olivera, B.M.2
  • 7
    • 19644387101 scopus 로고    scopus 로고
    • αS-conotoxin RVIIIA: A structurally unique conotoxin that broadly targets nicotinic acetylcholine receptors
    • DOI 10.1021/bi047274+
    • Teichert, R. W., Jimenez, E. C., and Olivera, B. M. (2005) αS-Conotoxin RVIIIA: A structurally unique conotoxin that broadly targets nicotinic acetylcholine receptors. Biochemistry 44, 7897-7902. (Pubitemid 40740773)
    • (2005) Biochemistry , vol.44 , Issue.21 , pp. 7897-7902
    • Teichert, R.W.1    Jimenez, E.C.2    Olivera, B.M.3
  • 8
    • 0025342986 scopus 로고
    • Constant and hypervariable regions in conotoxin propeptides
    • Woodward, S. R., Cruz, L. J., Olivera, B. M., and Hillyard, D. R. (1990) Constant and hypervariable regions in conotoxin prepropeptides. EMBO J. 9, 1015-1020. (Pubitemid 20110562)
    • (1990) EMBO Journal , vol.9 , Issue.4 , pp. 1015-1020
    • Woodward, S.R.1    Cruz, L.J.2    Olivera, B.M.3    Hillyard, D.R.4
  • 9
    • 11144319833 scopus 로고    scopus 로고
    • Were arachnids the first to use combinatorial peptide libraries?
    • DOI 10.1016/j.peptides.2004.07.016, PII S0196978104004723, Invertebrate Neuropeptides V
    • Sollod, B. L., Wilson, D., Zhaxybayeva, O., Gogarten, J. P., Drinkwater, R., and King, G. F. (2005) Were arachnids the first to use combinatorial peptide libraries? Peptides 26, 131-139. (Pubitemid 40038886)
    • (2005) Peptides , vol.26 , Issue.1 , pp. 131-139
    • Sollod, B.L.1    Wilson, D.2    Zhaxybayeva, O.3    Gogarten, J.P.4    Drinkwater, R.5    King, G.F.6
  • 11
    • 0036930324 scopus 로고    scopus 로고
    • Conus venom peptides: Reflections from the biology of clades and species
    • DOI 10.1146/annurev.ecolsys.33.010802.150424
    • Olivera, B. M. (2002) Conus venom peptides: Reflections from the biology of clades and species. Annu. ReV. Ecol. Syst. 33, 25-47. (Pubitemid 36035135)
    • (2002) Annual Review of Ecology and Systematics , vol.33 , pp. 25-47
    • Olivera, B.M.1
  • 12
    • 12344317094 scopus 로고    scopus 로고
    • Direct cDNA cloning of novel conopeptide precursors of the O-superfamily
    • DOI 10.1016/j.peptides.2004.10.027, PII S0196978104004863
    • Kauferstein, S., Melaun, C., and Mebs, D. (2005) Direct cDNA cloning of novel conopeptide precursors of the O-superfamily. Peptides 26, 361-367. (Pubitemid 40126691)
    • (2005) Peptides , vol.26 , Issue.3 , pp. 361-367
    • Kauferstein, S.1    Melaun, C.2    Mebs, D.3
  • 13
    • 4644305653 scopus 로고    scopus 로고
    • Novel conopeptides of the I-superfamily occur in several clades of cone snails
    • DOI 10.1016/j.toxicon.2004.07.006, PII S0041010104003095
    • Kauferstein, S., Huys, I., Kuch, U., Melaun, C., Tytgat, J., and Mebs, D. (2004) Novel conopeptides of the I-superfamily occur in several clades of cone snails. Toxicon 44, 539-548. (Pubitemid 39278377)
    • (2004) Toxicon , vol.44 , Issue.5 , pp. 539-548
    • Kauferstein, S.1    Huys, I.2    Kuch, U.3    Melaun, C.4    Tytgat, J.5    Mebs, D.6
  • 15
    • 0034894357 scopus 로고    scopus 로고
    • Cone venom-from accidental stings to deliberate injection
    • DOI 10.1016/S0041-0101(01)00145-3, PII S0041010101001453
    • McIntosh, J. M., and Jones, R. M. (2001) Cone venom-from accidental stings to deliberate injection. Toxicon 39, 1447-1451. (Pubitemid 32722031)
    • (2001) Toxicon , vol.39 , Issue.10 , pp. 1447-1451
    • McIntosh, J.M.1    Jones, R.M.2
  • 16
    • 0027248268 scopus 로고
    • Rapid amplification of complementary DNA ends for generation of full- Length complementary DNAs: Thermal RACE
    • Frohman, M. A. (1993) Rapid amplification of complementary DNA ends for generation of full-length complementary DNAs: thermal RACE. Methods Enzymol. 218, 340-356. (Pubitemid 23216122)
    • (1993) Methods in Enzymology , vol.218 , pp. 340-356
    • Frohman, M.A.1
  • 18
    • 0030614959 scopus 로고    scopus 로고
    • Identification of prokaryotic and enkaryotic signal peptides and prediction of their cleavage sites
    • Nielsen, H., Engelbrecht, J., Brunak, S., and von Heijne, G. (1997) Identification of prokaryotic and eukaryotic signal peptides and prediction of their cleavage sites. Protein Eng. 10, 1-6. (Pubitemid 27073346)
    • (1997) Protein Engineering , vol.10 , Issue.1 , pp. 1-6
    • Nielsen, H.1    Engelbrecht, J.2    Brunak, S.3    Von Heijne, G.4
  • 19
    • 3042521098 scopus 로고    scopus 로고
    • Improved prediction of signal peptides: SignalP 3.0
    • DOI 10.1016/j.jmb.2004.05.028, PII S0022283604005972
    • Bendtsen, J. D., Nielsen, H., von Heijne, G., and Brunak, S. (2004) Improved prediction of signal peptides: SignalP 3.0. J. Mol. Biol. 340, 783-795. (Pubitemid 38829638)
    • (2004) Journal of Molecular Biology , vol.340 , Issue.4 , pp. 783-795
    • Bendtsen, J.D.1    Nielsen, H.2    Von Heijne, G.3    Brunak, S.4
  • 20
    • 0842312524 scopus 로고    scopus 로고
    • Adaptive Evolution of Scorpion Sodium Channel Toxins
    • DOI 10.1007/s00239-003-2534-2
    • Zhu, S., Bosmans, F., and Tytgat, J. (2004) Adaptive evolution of scorpion sodium channel toxins. J. Mol. Evol. 58, 145-153. (Pubitemid 38183965)
    • (2004) Journal of Molecular Evolution , vol.58 , Issue.2 , pp. 145-153
    • Zhu, S.1    Bosmans, F.2    Tytgat, J.3
  • 22
    • 0037072765 scopus 로고    scopus 로고
    • α-Conotoxin GIC from Conus geographus, a novel peptide antagonist of nicotinic acetylcholine receptors
    • McIntosh, J. M., Dowell, C., Watkins, M., Garrett, J. E., Yoshikami, D., and Olivera, B. M. (2002) α-Conotoxin GIC from Conus geographus, a novel peptide antagonist of nicotinic acetylcholine receptors. J. Biol. Chem. 277, 33610-33615.
    • (2002) J. Biol. Chem. , vol.277 , pp. 33610-33615
    • McIntosh, J.M.1    Dowell, C.2    Watkins, M.3    Garrett, J.E.4    Yoshikami, D.5    Olivera, B.M.6
  • 24
    • 0038661000 scopus 로고    scopus 로고
    • A novel α-conotoxin identified by gene sequencing is active in suppressing the vascular response to selective stimulation of sensory nerves in vivo
    • DOI 10.1021/bi034043e
    • Sandall, D. W., Satkunanathan, N., Keays, D. A., Polidano, M. A., Liping, X., Pham, V., Down, J. G., Khalil, Z., Livett, B. G., and Gayler, K. R. (2003) A novel α-conotoxin identified by gene sequencing is active in suppressing the vascular response to selective stimulation of sensory nerves in vivo. Biochemistry 42, 6904-6911. (Pubitemid 36666131)
    • (2003) Biochemistry , vol.42 , Issue.22 , pp. 6904-6911
    • Sandall, D.W.1    Satkunanathan, N.2    Keays, D.A.3    Polidano, M.A.4    Liping, X.5    Pham, V.6    Down, J.G.7    Khalil, Z.8    Livett, B.G.9    Gayler, K.R.10
  • 26
    • 0037428436 scopus 로고    scopus 로고
    • α-conotoxins ImI and ImII: Similar α7 nicotinic receptor antagonists act at different sites
    • DOI 10.1074/jbc.M204565200
    • Ellison, M., McIntosh, J. M., and Olivera, B. M. (2003) α-Conotoxins ImI and ImII. Similar α7 nicotinic receptor antagonists act at different sites. J. Biol. Chem. 278, 757-764. (Pubitemid 36790747)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.2 , pp. 757-764
    • Ellison, M.1    McIntosh, J.M.2    Olivera, B.M.3
  • 27
    • 34249904657 scopus 로고    scopus 로고
    • Discovery, synthesis, and structure activity of a highly selective alpha7 nicotinic acetylcholine receptor antagonist
    • DOI 10.1021/bi7004202
    • Whiteaker, P., Christensen, S., Yoshikami, D., Dowell, C., Watkins, M., Gulyas, J., Rivier, J., Olivera, B. M., and McIntosh, J. M. (2007) Discovery, synthesis, and structure activity of a highly selective alpha7 nicotinic acetylcholine receptor antagonist. Biochemistry 46, 6628-6638. (Pubitemid 46870128)
    • (2007) Biochemistry , vol.46 , Issue.22 , pp. 6628-6638
    • Whiteaker, P.1    Christensen, S.2    Yoshikami, D.3    Dowell, C.4    Watkins, M.5    Gulyas, J.6    Rivier, J.7    Olivera, B.M.8    McIntosh, J.M.9
  • 29
    • 0034798344 scopus 로고    scopus 로고
    • Venomous cone snails: Molecular phylogeny and the generation of toxin diversity
    • DOI 10.1016/S0041-0101(01)00175-1, PII S0041010101001751
    • Espiritu, D. J. D., Watkins, M., Dia-Monje, V., Cartier, G. E., Cruz, L. J., and Olivera, B. M. (2001) Venomous cone snails: molecular phylogeny and the generation of toxin diversity. Toxicon 39, 1899-1916. (Pubitemid 32971831)
    • (2001) Toxicon , vol.39 , Issue.12 , pp. 1899-1916
    • Espiritu, D.J.D.1    Watkins, M.2    Dia-Monje, V.3    Cartier, G.E.4    Cruz, L.J.5    Olivera, B.M.6
  • 31
    • 0027968068 scopus 로고
    • CLUSTAL W: Improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice
    • Thompson, J. D., Higgins, D. G., and Gibson, T. J. (1994) CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res. 22, 4673-4680. (Pubitemid 24354800)
    • (1994) Nucleic Acids Research , vol.22 , Issue.22 , pp. 4673-4680
    • Thompson, J.D.1    Higgins, D.G.2    Gibson, T.J.3
  • 33
    • 0022507362 scopus 로고
    • Simple methods for estimating the numbers of synonymous and nonsynonymous nucleotide substitutions
    • Nei, M., and Gojobori, T. (1986) Simple methods for estimating the numbers of synonymous and nonsynonymous nucleotide substitutions. Mol. Biol. Evol. 3, 418-426. (Pubitemid 16010523)
    • (1986) Molecular Biology and Evolution , vol.3 , Issue.5 , pp. 418-426
    • Nei, M.1    Gojobori, T.2
  • 34
    • 34547781750 scopus 로고    scopus 로고
    • MEGA4: Molecular Evolutionary Genetics Analysis (MEGA) software version 4.0
    • DOI 10.1093/molbev/msm092
    • Tamura, K., Dudley, J., Nei, M., and Kumar, S. (2007) MEGA4: Molecular Evolutionary Genetics Analysis (MEGA) software version 4.0. Mol. Biol. Evol. 24, 1596-1599. (Pubitemid 47236692)
    • (2007) Molecular Biology and Evolution , vol.24 , Issue.8 , pp. 1596-1599
    • Tamura, K.1    Dudley, J.2    Nei, M.3    Kumar, S.4
  • 35
    • 21744458595 scopus 로고    scopus 로고
    • Precursors of novel Gla-containing conotoxins contain a carboxy-terminal recognition site that directs gamma-carboxylation
    • DOI 10.1021/bi0503293
    • Brown, M. A., Begley, G. S., Czerwiec, E., Stenberg, L. M., Jacobs, M., Kalume, D. E., Roepstorff, P., Stenflo, J., Furie, B. C., and Furie, B. (2005) Precursors of novel Gla-containing conotoxins contain a carboxy-terminal recognition site that directs gammacarboxylation. Biochemistry 44, 9150-9159. (Pubitemid 40943229)
    • (2005) Biochemistry , vol.44 , Issue.25 , pp. 9150-9159
    • Brown, M.A.1    Begley, G.S.2    Czerwiec, E.3    Stenberg, L.M.4    Jacobs, M.5    Kalume, D.E.6    Roepstorff, P.7    Stenflo, J.8    Furie, B.C.9    Furie, B.10
  • 37
    • 2642577647 scopus 로고    scopus 로고
    • Determining sequences and post-translational modifications of novel conotoxins in Conus victoriae using cDNA sequencing and mass spectrometry
    • DOI 10.1002/jms.624
    • Jakubowski, J. A., Keays, D. A., Kelley, W. P., Sandall, D. W., Bingham, J. P., Livett, B. G., Gayler, K. R., and Sweedler, J. V. (2004) Determining sequences and post-translational modifications of novel conotoxins in Conus victoriae using cDNA sequencing and mass spectrometry. J. Mass Spectrom. 39, 548-557. (Pubitemid 38714820)
    • (2004) Journal of Mass Spectrometry , vol.39 , Issue.5 , pp. 548-557
    • Jakubowski, J.A.1    Keays, D.A.2    Kelley, W.P.3    Sandall, D.W.4    Bingham, J.-P.5    Livett, B.G.6    Gayler, K.R.7    Sweedler, J.V.8
  • 38
    • 33845515677 scopus 로고    scopus 로고
    • Novel O-superfamily conotoxins identified by cDNA cloning from three vermivorous Conus species
    • Zhangsun, D., Luo, S., Wu, Y., Zhu, X., Hu, Y., and Xie, L. (2006) Novel O-superfamily conotoxins identified by cDNA cloning from three vermivorous Conus species. Chem. Biol. Drug Des. 68, 256-265.
    • (2006) Chem. Biol. Drug Des. , vol.68 , pp. 256-265
    • Zhangsun, D.1    Luo, S.2    Wu, Y.3    Zhu, X.4    Hu, Y.5    Xie, L.6
  • 40
    • 0032563252 scopus 로고    scopus 로고
    • Inactivation of a serotonin-gated ion channel by a polypeptide toxin from marine snails
    • DOI 10.1126/science.281.5376.575
    • England, L. J., Imperial, J., Jacobsen, R., Craig, A. G., Gukyas, J., Akhtar, M., Rivier, J., Julius, D., and Olivera, B. M. (1998) Inactivation of a serotonin-gated ion channel by a polypeptide toxin from marine snails. Science 281, 575-578. (Pubitemid 28357375)
    • (1998) Science , vol.281 , Issue.5376 , pp. 575-578
    • England, L.J.1    Imperial, J.2    Jacobsen, R.3    Craig, A.G.4    Gulyas, J.5    Akhtar, M.6    Rivier, J.7    Julius, D.8    Olivera, B.M.9
  • 41
    • 33644835885 scopus 로고    scopus 로고
    • Two novel O-superfamily conotoxins from Conus vexillum
    • DOI 10.1016/j.toxicon.2005.12.007, PII S0041010105004241
    • Jiang, H., Xu, C.-Q., Wang, C.-Z., Fan, C.-X., Zhao, T.-T., Chen, J.-S., and Chi, C.-W. (2006) Two novel O-superfamily conotoxins from Conus vexillum. Toxicon 47, 425-436. (Pubitemid 43363461)
    • (2006) Toxicon , vol.47 , Issue.4 , pp. 425-436
    • Jiang, H.1    Xu, C.-Q.2    Wang, C.-Z.3    Fan, C.-X.4    Zhao, T.-Y.5    Chen, J.-S.6    Chi, C.-W.7
  • 42
    • 23844444145 scopus 로고    scopus 로고
    • Characterization of D-amino-acid-containing excitatory conotoxins and redefinition of the I-conotoxin superfamily
    • DOI 10.1111/j.1742-4658.2005.04830.x
    • Buczek, O., Yoshkami, D., Watkins, M., Bulaj, G., Jiminez, E. C., and Olivera, B. M. (2005) Characterization of D-amino-acid-containing excitatory conotoxins and redefinition of the I-conotoxin superfamily. FEBS J. 272, 4178-4188. (Pubitemid 41160924)
    • (2005) FEBS Journal , vol.272 , Issue.16 , pp. 4178-4188
    • Buczek, O.1    Yoshikami, D.2    Watkins, M.3    Bulaj, G.4    Jimenez, E.C.5    Olivera, B.M.6
  • 43
    • 40649093511 scopus 로고    scopus 로고
    • Two different groups of signal sequence in M-superfamily conotoxins
    • Wang, Q., Jiang, H., Han, Y.-H., Yuan, D.-D., and Chi, C.-W. (2008) Two different groups of signal sequence in M-superfamily conotoxins. Toxicon 51, 813-822.
    • (2008) Toxicon , vol.51 , pp. 813-822
    • Wang, Q.1    Jiang, H.2    Han, Y.-H.3    Yuan, D.-D.4    Chi, C.-W.5
  • 44
    • 13944251765 scopus 로고    scopus 로고
    • Sequence diversity of T-superfamily conotoxins from Conus marmoreus
    • DOI 10.1016/j.toxicon.2004.12.008
    • Han, Y. H., Wang, Q., Jiang, H., Miao, X. W., Chen, J. S., and Chi, C. W. (2005) Sequence diversity of T-superfamily conotoxins from Conus marmoreus. Toxicon 45, 481-487. (Pubitemid 40269938)
    • (2005) Toxicon , vol.45 , Issue.4 , pp. 481-487
    • Han, Y.-H.1    Wang, Q.2    Jiang, H.3    Miao, X.-W.4    Chen, J.-S.5    Chi, C.-W.6
  • 45
    • 33751118759 scopus 로고    scopus 로고
    • Diversity and evolution of conotoxins based on gene expression profiling of Conus litteratus
    • Pi, C., Liu, J., Peng, C., Jiang, X., Zhao, Y., Tang, S., Wang, L., Dong, M., Chen, S., and Xu, A. (2006) Diversity and evolution of conotoxins based on gene expression profiling of Conus litteratus. Genomics 88, 809-819.
    • (2006) Genomics , vol.88 , pp. 809-819
    • Pi, C.1    Liu, J.2    Peng, C.3    Jiang, X.4    Zhao, Y.5    Tang, S.6    Wang, L.7    Dong, M.8    Chen, S.9    Xu, A.10
  • 46
    • 0032524834 scopus 로고    scopus 로고
    • Precursor convertases: An evolutionary ancient, cell-specific, combinatorial mechanism yielding diverse bioactive peptides and proteins
    • DOI 10.1111/j.1749-6632.1998.tb10727.x
    • Seidah, N. G., Day, R., Marcinkiewicz, M., and Chretien, M. (1998) Precursor convertases: an evolutionary ancient, cell-specific, combinatorial mechanism yielding diverse biocative peptides and proteins. Ann. N.Y. Acad. Sci. 839, 9-24. (Pubitemid 28301755)
    • (1998) Annals of the New York Academy of Sciences , vol.839 , pp. 9-24
    • Seidah, N.G.1    Day, R.2    Marcinkiewicz, M.3    Chretien, M.4
  • 47
    • 29344443859 scopus 로고    scopus 로고
    • Conotoxins and the posttranslational modification of secreted gene products
    • DOI 10.1007/s00018-005-5283-0
    • Buczek, O., Bulaj, G., and Olivera, B. M. (2005) Conotoxins and the posttranslational modification of secreted gene products. Cell. Mol. Life Sci. 62, 3067-3079. (Pubitemid 43004755)
    • (2005) Cellular and Molecular Life Sciences , vol.62 , Issue.24 , pp. 3067-3079
    • Buczek, O.1    Bulaj, G.2    Olivera, B.M.3
  • 48
    • 0032489509 scopus 로고    scopus 로고
    • Conantokin-G precursor and its role in gamma-carboxylation by a vitamin K- Dependent carboxylase from a Conus snail
    • DOI 10.1074/jbc.273.10.5447
    • Bandyopadhyay, P. K., Colledge, C. J., Walker, C. S., Zhou, L. M., Hillyard, D. R., and Olivera, B. M. (1998) Conantokin-G precursor and its role in gamma-carboxylation by a vitamin K-dependent carboxylase from a Conus snail. J. Biol. Chem. 273, 5447-5450. (Pubitemid 28124006)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.10 , pp. 5447-5450
    • Bandyopadhyay, P.K.1    Colledget, C.J.2    Walker, C.S.3    Zhou, L.-M.4    Hillyard, D.R.5    Olivera, B.M.6
  • 49
    • 0033517845 scopus 로고    scopus 로고
    • Hydrophobic amino acids define the carboxylation recognition site in the precursor of the gamma-carboxyglutamic-acid-containing conotoxin epsilon-TxIX from the marine cone snail Conus textile
    • Bush, K. A., Stenflo, J., Roth, D. A., Czerwiec, E., Harrist, A., Begley, G. S., Furie, B. C., and Furie, B. (1999) Hydrophobic amino acids define the carboxylation recognition site in the precursor of the gamma-carboxyglutamic- acid-containing conotoxin epsilon-TxIX from the marine cone snail Conus textile. Biochemistry 38, 14660-14666. (Pubitemid 129517608)
    • (1999) Biochemistry , vol.38 , Issue.44 , pp. 14660-14666
    • Bush, K.A.1    Stenflo, J.2    Roth, D.A.3    Czerwiec, E.4    Harrist, A.5    Begley, G.S.6    Furie, B.C.7    Furie, B.8
  • 50
    • 0030901614 scopus 로고    scopus 로고
    • Critical interactions at the dimer interface of kappa-bungarotoxin, a neuronal nicotinic acetylcholine receptor antagonist
    • DOI 10.1021/bi9629687
    • Grant, G. A., Al Rabiee, R., Xu, X. L., and Zhang, Y. P. (1997) Critical interactions at the dimer interface of kappa-bungarotoxin, a neuronal nicotinic acetylcholine receptor antagonist. Biochemistry 36, 3353-3358. (Pubitemid 27142409)
    • (1997) Biochemistry , vol.36 , Issue.11 , pp. 3353-3358
    • Grant, G.A.1    Al-Rabiee, R.2    Xu, X.L.3    Zhang, Y.4
  • 51
    • 0027944677 scopus 로고
    • Crystal structure of kappa-bungarotoxin at 2.3 angstrom resolution
    • DOI 10.1021/bi00248a026
    • Dewan, J. C., Grant, G. A., and Sacchettini, J. C. (1994) Crystal structure of kappa-bungarotoxin at 2.3 angstrom resolution. Biochemistry 33, 13147-13154. (Pubitemid 24364764)
    • (1994) Biochemistry , vol.33 , Issue.44 , pp. 13147-13154
    • Dewan, J.C.1    Grant, G.A.2    Sacchettini, J.C.3
  • 52
    • 0024441605 scopus 로고
    • Kappa-Neurotoxins: Heterodimer formation between different neuronal nicotinic receptor antagonists
    • Chiappinelli, V. A., and Wolf, K. M. (1989) Kappa-neurotoxins-Heterodimer formation between different neuronal nicotinic receptor antagonists. Biochemistry 28, 8543-8547. (Pubitemid 19269048)
    • (1989) Biochemistry , vol.28 , Issue.21 , pp. 8543-8547
    • Chiappinelli, V.A.1    Wolf, K.M.2
  • 53
    • 0034141795 scopus 로고    scopus 로고
    • Position-specific codon conservation in hypervariable gene families
    • DOI 10.1016/S0168-9525(99)01956-3, PII S0168952599019563
    • Conticello, S. G., Pilpel, Y., Glusman, G., and Fainzilber, M. (2000) Position-specific codon conservation in hypervariable gene families. Trends Genet. 16, 57-59. (Pubitemid 30084712)
    • (2000) Trends in Genetics , vol.16 , Issue.2 , pp. 57-59
    • Conticello, S.G.1    Pilpel, Y.2    Glusman, G.3    Fainzilber, M.4
  • 55
    • 33750705262 scopus 로고    scopus 로고
    • Novel α-conotoxins identified by gene sequencing from cone snails native to Hainan, and their sequence diversity
    • Luo, S., Zhangsun, D., Zhang, B., Quan, Y., and Wu, Y. (2006) Novel α-conotoxins identified by gene sequencing from cone snails native to Hainan, and their sequence diversity. J. Pept. Sci. 12, 693-704.
    • (2006) J. Pept. Sci. , vol.12 , pp. 693-704
    • Luo, S.1    Zhangsun, D.2    Zhang, B.3    Quan, Y.4    Wu, Y.5
  • 56
    • 27944494442 scopus 로고    scopus 로고
    • Analysis of expressed sequence tags from the venom ducts of Conus striatus: Focusing on the expression profile of conotoxins
    • DOI 10.1016/j.biochi.2005.08.001, PII S0300908405001938
    • Pi, C., Liu, Y., Peng, C., Jiang, X., Liu, J., Xu, B., Yu, X., Yu, Y., Jiang, X., Wang, L., Dong, M., Chen, S., and Xu, A.-L. (2006) Analysis of expressed sequence tags from the venom ducts of Conus striatus: focusing on the expression profile of conotoxins. Biochimie 88, 131-140. (Pubitemid 41668603)
    • (2006) Biochimie , vol.88 , Issue.2 , pp. 131-140
    • Pi, C.1    Liu, Y.2    Peng, C.3    Jiang, X.4    Liu, J.5    Xu, B.6    Yu, X.7    Yu, Y.8    Jiang, X.9    Wang, L.10    Dong, M.11    Chen, S.12    Xu, A.-L.13
  • 57
    • 28444479815 scopus 로고    scopus 로고
    • Molecular evolution of animal antimicrobial peptides: Widespread moderate positive selection
    • DOI 10.1111/j.1420-9101.2005.00925.x
    • Tennessen, J. A. (2005) Molecular evolution of animal antimicrobial peptides: widespread moderate positive selection. J. Mol. Evol. 18, 1387-1394. (Pubitemid 41727045)
    • (2005) Journal of Evolutionary Biology , vol.18 , Issue.6 , pp. 1387-1394
    • Tennessen, J.A.1
  • 58
    • 34748817463 scopus 로고    scopus 로고
    • Looking for Darwin in all the wrong places: The misguided quest for positive selection at the nucleotide sequence level
    • DOI 10.1038/sj.hdy.6801031, PII 6801031
    • Hughes, A. L. (2007) Looking for Darwin in all the wrong places: the misguided quest for positive selection at the nucleotide sequence level. Heredity 99, 364-373. (Pubitemid 47482647)
    • (2007) Heredity , vol.99 , Issue.4 , pp. 364-373
    • Hughes, A.L.1
  • 59
    • 33845367813 scopus 로고    scopus 로고
    • Molecular diversity of proteins in biological offense and defense systems
    • Ogawa, T. (2006) Molecular diversity of proteins in biological offense and defense systems. Mol. Divers. 10, 511-514.
    • (2006) Mol. Divers. , vol.10 , pp. 511-514
    • Ogawa, T.1
  • 61
    • 4143051195 scopus 로고    scopus 로고
    • Comparison of site-specific rate-inference methods for protein sequences: Empirical Bayesian methods are superior
    • DOI 10.1093/molbev/msh194
    • Mayrose, I., Graur, D., Ben-Tal, N., and Pupko, T. (2004) Comparison of site-specific rate-inference methods for protein sequences: Empirical Bayesian methods are superior. Mol. Biol. Evol. 21, 1781-1791. (Pubitemid 39096894)
    • (2004) Molecular Biology and Evolution , vol.21 , Issue.9 , pp. 1781-1791
    • Mayrose, I.1    Graur, D.2    Ben-Tal, N.3    Pupko, T.4
  • 62
    • 34547844134 scopus 로고    scopus 로고
    • Towards realistic codon models: Among site variability and dependency of synonymous and non-synonymous rates
    • DOI 10.1093/bioinformatics/btm176
    • Mayrose, I., Doron-Faigenboim, A., Bacharach, E., and Pupko, T. (2007) Towards realistic codon models: among site variability and dependency of synonymous and non-synonymous rates. Bioinformatics 23, I319-I327. (Pubitemid 47244416)
    • (2007) Bioinformatics , vol.23 , Issue.13
    • Mayrose, I.1    Doron-Faigenboim, A.2    Bacharach, E.3    Pupko, T.4
  • 63
    • 0034097381 scopus 로고    scopus 로고
    • Codon-substitution models for heterogeneous selection pressure at amino acid sites
    • Yang, Z. H., Nielsen, R., Goldman, N., and Pedersen, A. M. K. (2000) Codon-substitution models for heterogeneous selection pressure at amino acid sites. Genetics 155, 431-449. (Pubitemid 30257141)
    • (2000) Genetics , vol.155 , Issue.1 , pp. 431-449
    • Yang, Z.1    Nielsen, R.2    Goldman, N.3    Pedersen, A.-M.K.4
  • 64
    • 45449085031 scopus 로고    scopus 로고
    • Positive selection drives a correlation between non-synonymous/synonymous divergence and functional divergence
    • Tennessen, J. A. (2008) Positive selection drives a correlation between non-synonymous/synonymous divergence and functional divergence. Bioinformatics 24, 1421-1425.
    • (2008) Bioinformatics , vol.24 , pp. 1421-1425
    • Tennessen, J.A.1
  • 65
    • 33748424968 scopus 로고    scopus 로고
    • Secondary structure formations of conotoxin genes: A possible role in mediating variability
    • DOI 10.1016/j.bbrc.2006.08.081, PII S0006291X06018924
    • Dewan, K. D. (2006) Secondary structure formations of conotoxin genes: A possible role in mediating variability. Biochem. Biophys. Res. Commun. 349, 701-708. (Pubitemid 44344572)
    • (2006) Biochemical and Biophysical Research Communications , vol.349 , Issue.2 , pp. 701-708
    • Dewan, K.K.1
  • 66
    • 33845992556 scopus 로고    scopus 로고
    • Conus peptides: Biodiversity-based discovery and exogenomics
    • DOI 10.1074/jbc.R600020200
    • Olivera, B. M. (2006) Conus peptides: Biodiversity-based discovery and exogenomics. J. Biol. Chem. 281, 31173-31177. (Pubitemid 46041381)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.42 , pp. 31173-31177
    • Olivera, B.M.1
  • 67
    • 0019414348 scopus 로고
    • Peptide toxins from Conus geographus venom
    • Gray, W. R., Luque, A., Olivera, B. M., Barrett, J., and Cruz, L. J. (1981) Peptide toxins from Conus geographus venom. J. Biol. Chem. 256, 4734-4740. (Pubitemid 11035329)
    • (1981) Journal of Biological Chemistry , vol.256 , Issue.10 , pp. 4734-4740
    • Gray, W.R.1    Luque, A.2    Olivera, B.M.3
  • 68
    • 0022359989 scopus 로고
    • Conus geographus toxins that discriminate between neuronal and muscle sodium channels
    • Cruz, L. J., Gray, W. R., Olivera, B. M., Zeikus, R. D., Kerr, L., Yoshikami, D., and Moczydlowski, E. (1985) Conus geographus toxins that discriminate between neuronal and muscle sodium channels. J. Biol. Chem. 260, 9280-9288. (Pubitemid 16238310)
    • (1985) Journal of Biological Chemistry , vol.260 , Issue.16 , pp. 9280-9288
    • Cruz, L.J.1    Gray, W.R.2    Olivera, B.M.3
  • 71
    • 0021749660 scopus 로고
    • Purification and sequence of a presynaptic peptide toxin from Conus geographus venom
    • DOI 10.1021/bi00317a001
    • Olivera, B. M., McIntosh, J. M., Cruz, L. J., Luque, F. A., and Gray, W. R. (1984) Purification and sequence of a presynaptic peptide toxin from Conus geographus venom. Biochemistry 23, 5087-5090. (Pubitemid 15222100)
    • (1984) Biochemistry , vol.23 , Issue.22 , pp. 5087-5090
    • Olivera, B.M.1    McIntosh, J.M.2    Cruz, L.J.3
  • 74
    • 23944450557 scopus 로고    scopus 로고
    • A novel conotoxin from Conus delessertii with posttranslationally modified lysine residues
    • DOI 10.1021/bi050518l
    • Aguilar, M. B., LopezVera, E., Ortiz, E., Becerril, B., Possani, L. D., Olivera, B. M., and de la Cotera, E. P. H. (2005) A novel conotoxin from Conus delessertii with posttranslationally modified lysine residues. Biochemistry 44, 11130-11136. (Pubitemid 41209049)
    • (2005) Biochemistry , vol.44 , Issue.33 , pp. 11130-11136
    • Aguilar, M.B.1    Lopez-Vera, E.2    Ortiz, E.3    Becerril, B.4    Possani, L.D.5    Olivera, B.M.6    De La Cotera, E.P.H.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.