Elevated risk of chronic lymphocytic leukemia and other indolent non-Hodgkin's lymphomas among relatives of patients with chronic lymphocytic leukemia

Haematologica

Volumn 94, Issue 5, 2009, Pages 647-653

  Goldin, Lynn R ^a   Björkholm, Magnus ^b   Kristinsson, Sigurdur Y ^b   Turesson, Ingemar ^c   Landgren, Ola ^a,b  

^a NATIONAL CANCER INSTITUTE   (United States)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^c LUND UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Chronic lymphocytic leukemia; Familial risk; Non Hodgkin's lymphoma

Indexed keywords

ADULT; AGED; ARTICLE; CANCER RISK; CHRONIC LYMPHATIC LEUKEMIA; CONTROLLED STUDY; FAMILIAL DISEASE; FEMALE; GENETIC RISK; GENETIC SUSCEPTIBILITY; HAIRY CELL LEUKEMIA; HIGH RISK POPULATION; HODGKIN DISEASE; HUMAN; LYMPHOPROLIFERATIVE DISEASE; MAJOR CLINICAL STUDY; MALE; MONOCLONAL IMMUNOGLOBULINEMIA; MULTIPLE MYELOMA; NONHODGKIN LYMPHOMA; OUTCOMES RESEARCH; PATHOGENESIS; RELATIVE; RISK ASSESSMENT; SWEDEN; WALDENSTROEM MACROGLOBULINEMIA;

AGED; FAMILY; FAMILY HEALTH; FEMALE; HUMANS; LEUKEMIA, LYMPHOCYTIC, CHRONIC, B-CELL; LYMPHOMA, NON-HODGKIN; MALE; MIDDLE AGED; REGISTRIES; RISK FACTORS; SWEDEN;

EID: 66049151296     PISSN: 03906078     EISSN: 15928721     Source Type: Journal    
DOI: 10.3324/haematol.2008.003632     Document Type: Article

References (35)

1. Ries LAG, Melbert D, Krapcho M, Stinchcomb DG, Howlader N, Horner MJ, et al. SEER Cancer Statistics Review, 1975-2005, National Cancer Institute. 2008.
2. Linet MS, Schubauer-Berigan MK, Weisenburger DD, Richardson DB, Landgren O, Blair A, et al. Chronic lymphocytic leukaemia: an overview of aetiology in light of recent developments in classification and pathogenesis. Br J Haematol 2007;139:672-686
3. Goldin LR, Pfeiffer RM, Li X, Hemminki K. Familial risk of lymphoproliferative tumors in families of patients with chronic lymphocytic leukemia: results from the Swedish Family-Cancer Database. Blood 2004;104:1850-1854. (Pubitemid 39202296)
4. Goldin LR, Pfeiffer RM, Gridley G, Gail MH, Li X, Mellemkjaer L, et al. Familial aggregation of Hodgkin lymphoma and related tumors. Cancer 2004;100:1902-1908.
5. Goldin LR, Landgren O, McMaster ML, Gridley G, Hemminki K, Li X, et al. Familial aggregation and heterogeneity of non-Hodgkin lymphoma in population-based samples. Cancer Epidemiol Biomarkers Prev 2005;14:2402-2406
6. Cannon-Albright LA, Thomas A, Goldgar DE, Gholami K, Rowe K, Jacobsen M, et al. Familiality of cancer in Utah. Cancer Res 1994;54:2378-2385
7. Kerber RA, O'Brien E. A cohort study of cancer risk in relation to family histories of cancer in the Utah population database. Cancer 2005;103:1906-1915. (Pubitemid 40563264)
8. Kristinsson SY, Bjorkholm M, Goldin LR, McMaster ML, Turesson I, Landgren O. Risk of lymphoproliferative disorders among first-degree relatives of lymphoplasmacytic lymphoma/Waldenstrom macroglobulinemia patients: a population-based study in Sweden. Blood 2008;112:3052-3056
9. Goldin LR, Slager SL. Familial CLL: Genes and Environment. Hematology Am Soc Hematol Educ Program 2007;2007:339-345
10. Ishibe N, Sgambati MT, Fontaine L, Goldin LR, Jain N, Weissman N, et al. Clinical characteristics of familial B-CLL in the National Cancer Institute Familial Registry. Leuk Lymphoma 2001;42:99-108.
11. McMaster ML, Caporaso N. Waldenstrom macroglobulinaemia and IgM monoclonal gammopathy of undetermined significance: emerging understanding of a potential precursor condition. Br J Haematol 2007;139:663-671 (Pubitemid 350115717)
12. Sellick GS, Goldin LR, Wild RW, Slager SL, Ressenti L, Strom SS, et al. A high-density SNP genome-wide linkage search of 206 families identifies susceptibility loci for chronic lymphocytic leukemia. Blood 2007;110:3326-3333
13. Slager SL, Kay NE, Fredericksen ZS, Wang AH, Liebow M, Cunningham JM, et al. Susceptibility genes and Bchronic lymphocytic leukaemia. Br J Haematol 2007;139:762-771
14. Di Bernardo MC, Crowther-Swanepoel D, Broderick P, Webb E, Sellick G, Wild R, et al. A genome-wide association study identifies six susceptibility loci for chronic lymphocytic leukemia. Nat Genet 2008;40:1204-1210
15. Landgren O, Goldin LR, Kristinsson SY, Helgadottir EA, Samuelsson J, Bjorkholm M. Increased risks of polycythemia vera, essential thrombocythemia, and myelofibrosis among 24,577 first-degree relatives of 11,039 patients with myeloproliferative neoplasms in Sweden. Blood 2008;112:2199-2204
16. Jaffe ES, World Health Organization. Pathology and genetics of tumours of haematopoietic and lymphoid tissues. Lyon. Oxford: IARC Press; Oxford University Press. 2001.
17. Stansfeld AG, Diebold J, Noel H, Kapanci Y, Rilke F, Kelenyi G, et al. Updated Kiel classification for lymphomas. Lancet 1988;1:292-293
18. Morton LM, Turner JJ, Cerhan JR, Linet MS, Treseler PA, Clarke CA, et al. Proposed classification of lymphoid neoplasms for epidemiologic research from the Pathology Working Group of the International Lymphoma Epidemiology Consortium (InterLymph). Blood 2007;110:695-708.
19. Turesson I, Linet MS, Bjorkholm M, Kristinsson SY, Goldin LR, Caporaso NE, et al. Ascertainment and diagnostic accuracy for hematopoietic lymphoproliferative malignancies in Sweden 1964-2003. Int J Cancer 2007;121:2260-2266
20. Pfeiffer RM, Goldin LR, Chatterjee N, Daugherty S, Hemminki K, Pee D, et al. Methods for testing familial aggregation of diseases in population-based samples: application to Hodgkin lymphoma in Swedish registry data. Ann Hum Genet 2004;68:498-508.
21. Chng WJ, Schop RF, Price-Troska T, Ghobrial I, Kay N, Jelinek DF, et al. Gene-expression profiling of Waldenstrom macroglobulinemia reveals a phenotype more similar to chronic lymphocytic leukemia than multiple myeloma. Blood 2006;108:2755-2763
22. Lindblad K, Schalling M. Expanded repeat sequences and disease. Semin Neurol 1999;19:289-299
23. Vulliamy T, Marrone A, Szydlo R, Walne A, Mason PJ, Dokal I. Disease anticipation is associated with progressive telomere shortening in families with dyskeratosis congenita due to mutations in TERC. Nat Genet 2004;36:447-449 (Pubitemid 38620026)
24. Fraser FC. Trinucleotide repeats not the only cause of anticipation. Lancet 1997;350:459-460 (Pubitemid 27343299)
25. Vieland VJ, Huang J. Statistical evaluation of age-at-onset anticipation: a new test and evaluation of its behavior in realistic applications. Am J Hum Genet 1998;62:1212-1227 (Pubitemid 28199023)
26. Daugherty SE, Pfeiffer RM, Mellemkjaer L, Hemminki K, Goldin LR. No evidence for anticipation in lymphoproliferative tumors in population-based samples. Cancer Epidemiol Biomarkers Prev 2005;14:1245-1250 (Pubitemid 40656475)
27. Marti GE, Carter P, Abbasi F, Washington GC, Jain N, Zenger VE, et al. B-cell monoclonal lymphocytosis and B-cell abnormalities in the setting of familial B-cell chronic lymphocytic leukemia. Cytometry B Clin Cytom 2003;52:1-12.
28. Rawstron AC, Yuille MR, Fuller J, Cullen M, Kennedy B, Richards SJ, et al. Inherited predisposition to CLL is detectable as subclinical monoclonal B-lymphocyte expansion. Blood 2002;100:2289-2290
29. Fuller SJ, Papaemmanuil E, McKinnon L, Webb E, Sellick GS, Dao-Ung LP, et al. Analysis of a large multi-generational family provides insight into the genetics of chronic lymphocytic leukemia. Br J Haematol 2008;142:238-245
30. Fung SS, Hillier KL, Leger CS, Sandhu I, Vickars LM, Galbraith PF, et al. Clinical progression and outcome of patients with monoclonal B-cell lymphocytosis. Leuk Lymphoma 2007;48:1087-1091
31. Rawstron AC, Bennett FL, O'Connor SJ, Kwok M, Fenton JA, Plummer M, et al. Monoclonal B-cell lymphocytosis and chronic lymphocytic leukemia. N Engl J Med 2008;359:575-583
32. Shanafelt TD, Kay NE, Jenkins G, Call TG, Zent CS, Jelinek DF, et al. B-cell count and survival: differentiating chronic lymphocytic leukemia (CLL) from monoclonal B-cell lymphocytosis (MBL) based on clinical outcome. Blood 2008[Epub ahead of print].
33. Konda A, Duffy MC. Surveillance of patients at increased risk of colon cancer: inflammatory bowel disease and other conditions. Gastroenterol Clin North Am 2008;37:191-213.
34. Hardy NM, Grady C, Pentz R, Stetler-Stevenson M, Raffeld M, Fontaine LS, et al. Bioethical considerations of monoclonal B-cell lymphocytosis: donor transfer after haematopoietic stem cell transplantation. Br J Haematol 2007;139:824-831
35. Landgren O, Rapkin JS, Caporaso NE, Mellemkjaer L, Gridley G, Goldin LR, et al. Respiratory tract infections and subsequent risk of chronic lymphocytic leukemia. Blood 2007;109:2198-2201