Differences in lung glutathione metabolism may account for rodent susceptibility in elastase-induced emphysema development

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 296, Issue 4, 2009, Pages

  Borzone, Gisella R ^a   Liberona, Leonel F ^a   Bustamante, Andrea P ^a   Saez, Claudia G ^a   Olmos, Pablo R ^a   Vecchiola, Andrea ^a   Villagrán, Andrea ^a   Serrano, Carolina ^a   Reyes, Tatiana P ^a  

^a PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE   (Chile)

Author keywords

glutamyl cysteine synthetase; Diffuse alveolar damage; Glutathione peroxidase; Glutathione reductase; Lung susceptibility to elastase; Pulmonary emphysema

Indexed keywords

ALPHA 1 ANTITRYPSIN; ELASTASE; GLUTAMATE CYSTEINE LIGASE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISEASE COURSE; DISEASE PREDISPOSITION; DISEASE SEVERITY; ENZYME ACTIVITY; ENZYME METABOLISM; EXPERIMENTAL RAT; GLUTATHIONE METABOLISM; HAMSTER; HOMEOSTASIS; LUNG ALVEOLUS; LUNG EMPHYSEMA; LUNG INJURY; MALE; NONHUMAN; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SPECIES DIFFERENCE;

ALPHA 1-ANTITRYPSIN; ANIMALS; BRONCHOALVEOLAR LAVAGE FLUID; CRICETINAE; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GLUTAMATE-CYSTEINE LIGASE; GLUTATHIONE; GLUTATHIONE DISULFIDE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; LUNG; MALE; MESOCRICETUS; OXIDATION-REDUCTION; OXIDATIVE STRESS; PANCREATIC ELASTASE; PULMONARY EMPHYSEMA; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; SEVERITY OF ILLNESS INDEX; SPECIES SPECIFICITY; TIME FACTORS;

EID: 65949100121     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.90361.2008     Document Type: Article

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