Experimental pulmonary emphysema in the rat. Inflammatory phenomena and progression of lung damage;Enfisema pulmonar experimental en la rata: Fenómenos inflamatorios y progresión del daño pulmonar

Revista Medica de Chile

Volumn 126, Issue 10, 1998, Pages 1153-1160

  Borzone T, Gisella ^b   Ramírez U, Beatriz ^a   Reyes R, Tatiana ^c   Moreno B, Rodrigo ^c   Lisboa B, Carmen ^c   González B, Sergio ^c  

^a UNIVERSIDAD DE SANTIAGO DE CHILE   (Chile)

^b PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE   (Chile)

^c NONE

Author keywords

Inflammation; Lung diseases; Pulmonary emphysema

Indexed keywords

PANCREATIC ELASTASE;

ANIMAL; ARTICLE; CHEMICALLY INDUCED DISORDER; DISEASE COURSE; DISEASE MODEL; ENZYMOLOGY; LUNG; LUNG EMPHYSEMA; MALE; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; RAT; SPRAGUE DAWLEY RAT;

ANIMALS; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; LUNG; MALE; PANCREATIC ELASTASE; PULMONARY EMPHYSEMA; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0007588409     PISSN: 00349887     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (17)

1. LUCEY EC. Experimental emphysema. Clinics in Chest Medicine 1983; 4: 389-403.
2. STONE PJ. The elastase-antielastase hypothesis of the pathogenesis of emphysema. Clinics in Chest Medicine 1983; 4: 405-12.
3. CANTOR JO, TURINO G. Animal models of emphysema. En: Cherniack NS, ed. Chronic obstructive pulmonary disease. Philadelphia: Editorial Saunders Co. 1991; 63-9.
4. SNIDER GL, LUCEY EC, STONE PJ. Animal models of emphysema. Am Rev Respir Dis 1986; 133: 149-69.
5. SNIDER GL, SHERTER CB. A one-year study of the evolution of elastase-induced emphysema in hamsters. J Appl Physiol 1977; 43: 721-9.
6. SENIOR RM, TEGNER H, FUHN CH, OHLSSON K, STARCHER B, PIERCE J. The induction of pulmonary emphysema with human leukocyte elastase. Am Rev Respir Dis 1977; 116: 469-75.
7. GILES RE, FINKEL MP, LEEDS R. The production of an emphysema-like condition in rats by the administration of papain aerosol. Proc Soc Exp Biol Med 1970; 134-57.
8. PUSHPAKOM R, HOGG JC, WOOLCOCK A, ANGUS AE, MACKLEM PT, THURLBECK WM. Experimental papain-induced emphysema in dogs. Am Rev Respir Dis 1970; 102: 778-9.
9. THOMAS AJ, SUPINSKI GS, KELSEN SG. Changes in chest wall structure and elasticity in elastase-induced emphysema. J Appl Physiol 1986; 61: 1821-9.
10. FARKAS GA, ROUSSOS C. Diaphragm in emphysematous hamsters: sarcomere adaptability. J Appl Physiol 1983; 54: 1635-40.
11. MARTIN TR, RAGHU G, MAUNDER RJ, SPRINGMEYER S. The effects of chronic bronchitis and chronic airflow obstruction on lung cell population recovered by bronchoalveolar lavage. Am Rev Respir Dis 1985; 132: 254-60.
12. STONE PJ, PEREIRA W, BILES D, SNIDER GL, KAGAN H, FRANZBLAU C. Studies on the fate of pancreatic elastase in the hamster lung: 14C-guanidinated elastase. Am Rev Respir Dis 1977; 116: 49-56.
13. MORRIS SH, STONE PJ, SNIDER GL, ALBRIGHT JT, FRANZBLAU G. Autoradiographic study of 3H-methylated elastase in hamster lungs. Anat Rec 1983; 206: 31-42.
14. ANDERSON AE, FORAKER AG. Pathogenic implications of alveolitis in pulmonary emphysema. Arch Pathol Lab Med 1961; 72: 44-58.
15. FINKELSTEIN R, FRASER RS, GHEZZO H, COSSIO MG. Alveolar inflammation and its relation to emphysema in smokers. Am J Respir Crit Care Med 1995; 152: 1666-72.
16. SOKAL RR, ROHLF FJ. (ed.) Biometry. New York. WH Freeman and Co 1981; 607.
17. SAETTA M, KIM WD, IZQUIERDO JL, GHEZZO H, COSSIO MG. Extent of centrilobular and panacinar emphysema in smoker's lungs: pathological and mechanical implications. Eur Respir J 1994; 7: 664-71.