Serum vascular endothelial growth factor: A prognostic factor in cervical cancer

Journal of Cancer Research and Clinical Oncology

Volumn 135, Issue 2, 2009, Pages 283-290

  Zusterzeel, Petra L M ^a   Span, Paul N ^a   Dijksterhuis, Marja G K ^a,b   Thomas, Chris M G ^a   Sweep, Fred C G J ^a   Massuger, Leon F A G ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b IKAZIA HOSPITAL   (Netherlands)

Author keywords

Angiogenesis; Cervical cancer; Prognostic value; Survival; Vascular endothelial growth factor; VEGF

Indexed keywords

TUMOR MARKER; VASCULOTROPIN A;

ADULT; AGED; ARTICLE; BLOOD; CANCER STAGING; DISEASE COURSE; FEMALE; HUMAN; MIDDLE AGED; MORTALITY; MULTIVARIATE ANALYSIS; PATHOLOGY; PROGNOSIS; PROPORTIONAL HAZARDS MODEL; REGRESSION ANALYSIS; SURVIVAL; UTERINE CERVIX TUMOR;

ADULT; AGED; AGED, 80 AND OVER; DISEASE PROGRESSION; FEMALE; HUMANS; MIDDLE AGED; MULTIVARIATE ANALYSIS; NEOPLASM STAGING; PROGNOSIS; PROPORTIONAL HAZARDS MODELS; REGRESSION ANALYSIS; SURVIVAL ANALYSIS; TUMOR MARKERS, BIOLOGICAL; UTERINE CERVICAL NEOPLASMS; VASCULAR ENDOTHELIAL GROWTH FACTOR A; YOUNG ADULT;

EID: 65849208749     PISSN: 01715216     EISSN: 14321335     Source Type: Journal    
DOI: 10.1007/s00432-008-0442-y     Document Type: Article

References (26)

1. Bachtiary B, Selzer E, Knocke TH, Pötter R, Obermair A (2002) Serum VEGF levels in patients undergoing primary radiotherapy for cervical cancer: impact on progression-free survival. Cancer Lett 179:197-203. doi:10.1016/S0304-3835(01)00872-2
2. Cheng WF, Chen CA, Lee CN, Wei LH, Hsieh FJ, Hsieh CY (2000) Vascular endothelial growth factor and prognosis of cervical carcinoma. Obstet Gynecol 96:721-726. doi:10.1016/S0029-7844(00)01025-5
3. Dobbs SP, Hewett PW, Johnson IR, Carmichael J, Murray JC (1997) Angiogenesis is associated with vascular endothelial growth factor expression in cervical intraepithelial neoplasia. Br J Cancer 76:1410-1415
4. Ferrara N (1995) The role of vascular endothelial growth factor in pathological angiogenesis. Breast Cancer Res Treat 36:127-137. doi:10.1007/BF00666035
5. Ferrara N, Vis-Smyth T (1997) The biology of vascular endothelial growth factor. Endocr Rev 18:4-25. doi:10.1210/er.18.1.4
6. Folkman J (1990) What is the evidence that tumors are angiogenesis dependent? J Natl Cancer Inst 82:4-6. doi:10.1093/jnci/82.1.4
7. Folkman J (1995) Angiogenesis in cancer, vascular, rheumatoid and other disease. Nat Med 1:27-31. doi:10.1038/nm0195-27
8. Fujimoto J, Sakaguchi H, Hirose R, Ichigo S, Tamaya T (1999) Expression of vascular endothelial growth factor (VEGF) and its mRNA in uterine cervical cancers. Br J Cancer 80:827-833. doi:10.1038/sj.bjc.6690428
9. Fukumura D, Xavier R, Sugiura T, Chen Y, Park EC, Lu N et al (1998) Tumor induction of VEGF promoter activity in stromal cells. Cell 94:715-725. doi:10.1016/S0092-8674(00)81731-6
10. Gadducci A, Tana R, Cosio S, Genazzani AR (2007) The serum assay of tumour markers in the prognostic evaluation, treatment monitoring and follow-up of patients with cervical cancer: a review of the literature. Crit Rev Oncol Hematol 66(1):10-20
11. Kaku T, Hirakawa T, Kamura T, Amada S, Kinukawa N, Kobayashi H et al (1998) Angiogenesis in adenocarcinoma of the uterine cervix. Cancer 83:1384-1390 10.1002/(SICI)1097-0142 (19981001)83:7〈l1384::AID-CNCR16〉3.0.CO;2-0
12. Kristensen GB, Abeler VM, Risberg B, Trop C, Bryne M (1999) Tumor size, depth of invasion, and grading of the invasive tumor front are the main prognostic factors in early squamous cell cervical carcinoma. Gynecol Oncol 74:245-251. doi:10.1006/gyno.1999.5420
13. Lagasse LD, Creasman WT, Shingleton HM, Ford JH, Blessing JA (1980) Results and complications of operative staging in cervical cancer: experience of the Gynecologic Oncology Group. Gynecol Oncol 9:90-98. doi:10.1016/0090- 8258(80)90013-X
14. Lebrecht A, Ludwig E, Huber A, Klein M, Schneeberger C, Tempfer C et al (2002) Serum vascular endothelial growth factor and serum leptin in patients with cervical cancer. Gynecol Oncol 85:32-35. doi:10.1006/gyno.2001.6517
15. Lee IJ, Park KR, Lee KK, Song JS, Lee KG, Lee JY et al (2002) Prognostic value of vascular endothelial growth factor in stage IB carcinoma of the uterine cervix. Int J Radiat Oncol Biol Phys 54:768-779. doi:10.1016/S0360-3016(02) 02970-X
16. Loncaster JA, Cooper RA, Logue JP, Davidson SE, Hunter RD, West CM (2000) Vascular endothelial growth factor (VEGF) expression is a prognostic factor for radiotherapy outcome in advanced carcinoma of the cervix. Br J Cancer 83:620-625. doi:10.1054/bjoc.2000.1319
17. Massuger LF, Koper NP, Thomas CM, Dom KE, Schijf CP (1997) Improvement of clinical staging in cervical cancer with serum squamous cell carcinoma antigen and CA 125 determinations. Gynecol Oncol 64:473-476. doi:10.1006/gyno.1996.4581
18. Mitsuhashi A, Suzuka K, Yamazawa K, Matsui H, Seki K, Sekiya S (2005) Serum vascular endothelial growth factor (VEGF) and VEGF-C levels as tumor markers in patients with cervical carcinoma. Cancer 103:724-730. doi:10.1002/cncr.20819
19. Moon HS, Kim SC, Ahn JJ, Woo BH (2000) Concentration of vascular endothelial growth factor (VEGF) and transforming growth factor-beta1 (TGF-beta1) in the serum of patients with cervical cancer: prediction of response. Int J Gynecol Cancer 10:151-156. doi:10.1046/j.1525-1438.2000.00013.x
20. Nguyen HN, Averette HE (1999) Biology of cervical carcinoma. Semin Surg Oncol 16:212-216 10.1002/(SICI)1098-2388(199904/05)16:3〈212::AID- SSU3〉3.0.CO;2-B
21. Obermair A, Wanner C, Bilgi S, Speiser P, Kaider A, Reinthaller A et al (1998) Tumor angiogenesis in stage IB cervical cancer: correlation of microvessel density with survival. Am J Obstet Gynecol 178:314-319. doi:10.1016/S0002-9378(98)80018-5
22. Samlal RA, van der Velden J, Schilthuis MS, González González D, Ten Kate FJ, Hart AA et al (1997) Identification of high-risk groups among node-positive patients with stage IB and IIA cervical carcinoma. Gynecol Oncol 64:463-467. doi:10.1006/gyno.1996.4576
23. Span PN, Grebenchtchikov N, Geurts-Moespot J, Westphal JR, Lucassen AM, Sweep CG (2000) EORTC Receptor and Biomarker Study Group Report: a sandwich enzyme-linked immunosorbent assay for vascular endothelial growth factor in blood and tumor tissue extracts. Int J Biol Markers 15:184-191
24. Tjalma W, Weyler J, Weyn B, Van Marck E, Van Daele A, Van Dam P et al (2000) The association between vascular endothelial growth factor, microvessel density and clinicopathological features in invasive cervical cancer. Eur J Obstet Gynecol Reprod Biol 92:251-257. doi:10.1016/S0301-2115(99)00295-X
25. Wiggins DL, Granai CO, Steinhoff MM, Calabresi P (1995) Tumor angiogenesis as a prognostic factor in cervical carcinoma. Gynecol Oncol 56:353-356. doi:10.1006/gyno.1995.1062
26. Yang YC, Wang KL, Su TH, Liao HF, Wu MH, Chen TC et al (2006) Concurrent cisplatin-based chemoradiation for cervical carcinoma: tumor response, toxicity, and serum cytokine proWles. Cancer Invest 24:390-395. doi:10.1080/ 07357900600705359