-
3
-
-
17744364264
-
-
Steckler T., Lavreysen H., Oliveira A.M., Aerts N., Van Craenendonck H., Prickaerts J., Megens A., and Lesage A.S.J. Psychopharmacology 179 (2005) 198
-
(2005)
Psychopharmacology
, vol.179
, pp. 198
-
-
Steckler, T.1
Lavreysen, H.2
Oliveira, A.M.3
Aerts, N.4
Van Craenendonck, H.5
Prickaerts, J.6
Megens, A.7
Lesage, A.S.J.8
-
5
-
-
0034718925
-
-
Kunishima N., Shimada Y., Tsuji Y., Sato T., Yamamoto M., Kumasaka T., Nakanishi S., Jingami H., and Morikawa K. Nature 407 (2000) 971
-
(2000)
Nature
, vol.407
, pp. 971
-
-
Kunishima, N.1
Shimada, Y.2
Tsuji, Y.3
Sato, T.4
Yamamoto, M.5
Kumasaka, T.6
Nakanishi, S.7
Jingami, H.8
Morikawa, K.9
-
8
-
-
0034676328
-
-
Ott D., Floersheim P., Inderbitzin W., Stoehr N., Francotte E., Lecis G., Richert P., Rihs G., Flor P.J., Kuhn R., and Gasparini F. J. Med. Chem. 43 (2000) 4428
-
(2000)
J. Med. Chem.
, vol.43
, pp. 4428
-
-
Ott, D.1
Floersheim, P.2
Inderbitzin, W.3
Stoehr, N.4
Francotte, E.5
Lecis, G.6
Richert, P.7
Rihs, G.8
Flor, P.J.9
Kuhn, R.10
Gasparini, F.11
-
9
-
-
0037424518
-
-
Malherbe P., Kratochwil N., Knoflach F., Zenner M.-T., Kew J.N.C., Kratzeisen C., Maerki H.P., Adam G., and Mutel V. J. Biol. Chem. 278 (2003) 8340
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 8340
-
-
Malherbe, P.1
Kratochwil, N.2
Knoflach, F.3
Zenner, M.-T.4
Kew, J.N.C.5
Kratzeisen, C.6
Maerki, H.P.7
Adam, G.8
Mutel, V.9
-
10
-
-
0035028011
-
-
Carroll F.Y., Stolle A., Beart P.M., Voerste A., Brabet I., Mauler F., Joly C., Antonicek H., Bockaert J., Müller T., Pin J.P., and Prézeau L. Mol. Pharmacol. 59 (2001) 965
-
(2001)
Mol. Pharmacol.
, vol.59
, pp. 965
-
-
Carroll, F.Y.1
Stolle, A.2
Beart, P.M.3
Voerste, A.4
Brabet, I.5
Mauler, F.6
Joly, C.7
Antonicek, H.8
Bockaert, J.9
Müller, T.10
Pin, J.P.11
Prézeau, L.12
-
11
-
-
8844229596
-
-
Lavreysen H., Wouters R., Bischoff F., Pereira S.N., Langlois X., Blokland S., Somers M., Dillen L., and Lesage A.S.J. Neuropharmacology 47 (2004) 961
-
(2004)
Neuropharmacology
, vol.47
, pp. 961
-
-
Lavreysen, H.1
Wouters, R.2
Bischoff, F.3
Pereira, S.N.4
Langlois, X.5
Blokland, S.6
Somers, M.7
Dillen, L.8
Lesage, A.S.J.9
-
12
-
-
20944438126
-
-
Varty G.B., Grilli M., Forlani A., Fredduzzi S., Grzelak M.E., Guthrie D.H., Hodgson R.A., Sherry X.L., Nicolussi E., Pond A.J., Parker E.M., Hunter J.C., Higgins G.A., Reggiani A., and Bertorelli R. Psychopharmacology 179 (2005) 207
-
(2005)
Psychopharmacology
, vol.179
, pp. 207
-
-
Varty, G.B.1
Grilli, M.2
Forlani, A.3
Fredduzzi, S.4
Grzelak, M.E.5
Guthrie, D.H.6
Hodgson, R.A.7
Sherry, X.L.8
Nicolussi, E.9
Pond, A.J.10
Parker, E.M.11
Hunter, J.C.12
Higgins, G.A.13
Reggiani, A.14
Bertorelli, R.15
-
13
-
-
28544443384
-
-
Recently, scientists from Abbott Laboratories disclosed similar mGluR1 antagonists based on the tricyclic triazafluorenone core structure. See:
-
Recently, scientists from Abbott Laboratories disclosed similar mGluR1 antagonists based on the tricyclic triazafluorenone core structure. See:. Zheng G.Z., Bhatia P., Daanen J., Kolasa T., Patel M., Latshaw S., Kouhen O.F.E., Chang R., Uchic M.E., Miller L., Nakane M., Lehto S.G., Honore M.P., Moreland R.B., Brioni J.D., and Stewart A.O. J. Med. Chem. 48 (2005) 7374
-
(2005)
J. Med. Chem.
, vol.48
, pp. 7374
-
-
Zheng, G.Z.1
Bhatia, P.2
Daanen, J.3
Kolasa, T.4
Patel, M.5
Latshaw, S.6
Kouhen, O.F.E.7
Chang, R.8
Uchic, M.E.9
Miller, L.10
Nakane, M.11
Lehto, S.G.12
Honore, M.P.13
Moreland, R.B.14
Brioni, J.D.15
Stewart, A.O.16
-
14
-
-
36149000929
-
-
Our efforts in the modification of tricyclic structure is being published in the following patents, WO 2006/002051 and US 2006/167029. Also see: Biology materials and methods were described in this Letter
-
Our efforts in the modification of tricyclic structure is being published in the following patents, WO 2006/002051 and US 2006/167029. Also see:. Wu W.-L., Burnett D.A., Domalski D., Greenlee W.J., Li C., Bertorelli R., Fredduzzi S., Lozza G., Veltri A., and Reggiani A. J. Med. Chem 50 (2007) 5550 Biology materials and methods were described in this Letter
-
(2007)
J. Med. Chem
, vol.50
, pp. 5550
-
-
Wu, W.-L.1
Burnett, D.A.2
Domalski, D.3
Greenlee, W.J.4
Li, C.5
Bertorelli, R.6
Fredduzzi, S.7
Lozza, G.8
Veltri, A.9
Reggiani, A.10
-
15
-
-
65749096494
-
-
note
-
+ = 344.03, found m/z = 344.2.
-
-
-
-
17
-
-
65749095946
-
-
note
-
+ = 350.11, found m/z = 350.2.
-
-
-
-
18
-
-
0035100437
-
-
Korfmacher W.A., Cox K.A., Ng K.J., Veals J., Hsien Y., Wainhaus S., Broske L., Prelusky D., Nomeir A., and White R.E. Rapid Commun. Mass. Spectrom. 15 (2001) 335
-
(2001)
Rapid Commun. Mass. Spectrom.
, vol.15
, pp. 335
-
-
Korfmacher, W.A.1
Cox, K.A.2
Ng, K.J.3
Veals, J.4
Hsien, Y.5
Wainhaus, S.6
Broske, L.7
Prelusky, D.8
Nomeir, A.9
White, R.E.10
-
19
-
-
0033788645
-
-
Banijamali A.R., Xu Y., DeMatteo V., Strunk R.J., and Sumner S.J. J. Agric. Food Chem. 48 (2000) 4693
-
(2000)
J. Agric. Food Chem.
, vol.48
, pp. 4693
-
-
Banijamali, A.R.1
Xu, Y.2
DeMatteo, V.3
Strunk, R.J.4
Sumner, S.J.5
-
20
-
-
0020382322
-
-
DeMaster E.G., Sumner H.W., Kaplan E., Shirota F.N., and Nagasawa H.T. Toxicol. Pharmacol. 65 (1982) 390
-
(1982)
Toxicol. Pharmacol.
, vol.65
, pp. 390
-
-
DeMaster, E.G.1
Sumner, H.W.2
Kaplan, E.3
Shirota, F.N.4
Nagasawa, H.T.5
|