Stereoselective synthesis of tubuvaline methyl ester and tubuphenylalanine, components of tubulysins, tubulin polymerization inhibitors

Tetrahedron Letters

Volumn 50, Issue 27, 2009, Pages 3845-3848

  Shibue, Taku ^a   Hirai, Toshihiro ^b   Okamoto, Iwao ^b   Morita, Nobuyoshi ^b   Masu, Hyuma ^c   Azumaya, Isao ^c   Tamura, Osamu ^b  

^a KYORIN PHARMACEUTICAL CO LTD   (Japan)

^b SHOWA PHARMACEUTICAL UNIVERSITY   (Japan)

^c TOKUSHIMA BUNRI UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACRYLIC ACID DERIVATIVE; ALDEHYDE; AMPHOLYTE; BORON DERIVATIVE; NITRONE DERIVATIVE; OXAZOLIDINONE DERIVATIVE; PHENYLALANINE; TETRAPEPTIDE; TUBUPHENYLALANINE; TUBUVALINE METHYL ESTER; UNCLASSIFIED DRUG;

ALDOL REACTION; ARTICLE; CYCLOADDITION; DEOXYGENATION; DRUG SYNTHESIS; MICROTUBULE ASSEMBLY; RADICAL REACTION; STEREOCHEMISTRY;

EID: 65649147600     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2009.04.046     Document Type: Article

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