Structure-activity relationships in peptide-antibody complexes: Implications for epitope prediction and development of synthetic peptide vaccines

Current Medicinal Chemistry

Volumn 16, Issue 8, 2009, Pages 953-964

  Chen, Shu Wen W ^a   Van Regenmortel, Marc H V ^b   Pellequer, Jean Luc ^c  

^a CNRS ^*  (France)

^b UNIVERSITÉ DE STRASBOURG   (France)

^c DIF   (France)

Author keywords

Hot spots; Level set method; Protein ligand recognition; Protein protein interface; Structural bioinformatics; Synthetic vaccine; X ray structures

Indexed keywords

EPITOPE; PEPTIDE VACCINE;

AMINO ACID SEQUENCE; ANTIGEN ANTIBODY COMPLEX; COMPLEX FORMATION; MOLECULAR INTERACTION; MOLECULAR RECOGNITION; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE; REVIEW; SEQUENCE ANALYSIS; STRUCTURAL BIOINFORMATICS; STRUCTURAL HOMOLOGY; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; SURFACE PROPERTY; VACCINE PRODUCTION;

ANTIBODIES; CHOLERA TOXIN; CROSS REACTIONS; DATABASES, PROTEIN; EPITOPES; PEPTIDES; PROTEIN STRUCTURE, SECONDARY; STRUCTURE-ACTIVITY RELATIONSHIP; VACCINES, SUBUNIT; VACCINES, SYNTHETIC;

EID: 65649123444     PISSN: 09298673     EISSN: None     Source Type: Journal    
DOI: 10.2174/092986709787581914     Document Type: Review

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