Analysis of the oestrogen response in an angiomyolipoma derived xenograft model

Endocrine-Related Cancer

Volumn 16, Issue 1, 2009, Pages 59-72

  Clements, Debbie ^a   Asprey, Sarah L ^a   McCulloch, Thomas A ^b   Morris, Theresa A ^c   Watson, Susan A ^c   Johnson, Simon R ^a  

^a NOTTINGHAM UNIVERSITY HOSPITALS NHS TRUST   (United Kingdom)

^b NOTTINGHAM CITY HOSPITAL   (United Kingdom)

^c UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CYCLE PROTEIN; CELL PROTEIN; ESTROGEN; GROWTH FACTOR; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PLATELET DERIVED GROWTH FACTOR C; PROTEIN KINASE B; PROTEINASE; S6 KINASE; SYNAPTOPHYSIN; LYMPHOKINE; MTORC1 PROTEIN, MOUSE; PLATELET DERIVED GROWTH FACTOR; PLATELET-DERIVED GROWTH FACTOR C; TRANSCRIPTION FACTOR;

ANGIOMYOLIPOMA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARCINOGENESIS; CELL GROWTH; CELL IMMORTALIZATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; GENE INDUCTION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LYMPHANGIOLEIOMYOMATOSIS; MOUSE; NONHUMAN; NUDE MOUSE; PROTEIN SYNTHESIS; SMOOTH MUSCLE FIBER; TUMOR XENOGRAFT; ANIMAL; CELL LINE; DRUG EFFECT; DRUG SCREENING; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETICS; LUNG TUMOR; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; SIGNAL TRANSDUCTION;

ANGIOMYOLIPOMA; ANIMALS; CELL LINE, TRANSFORMED; ESTROGENS; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LUNG NEOPLASMS; LYMPHANGIOLEIOMYOMATOSIS; LYMPHOKINES; MAP KINASE SIGNALING SYSTEM; MICE; MICE, NUDE; PLATELET-DERIVED GROWTH FACTOR; PROTO-ONCOGENE PROTEINS C-AKT; RIBOSOMAL PROTEIN S6 KINASES, 70-KDA; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 65549165944     PISSN: 13510088     EISSN: 14796821     Source Type: Journal    
DOI: 10.1677/ERC-08-0123     Document Type: Article

References (44)

1. Arbiser JL, Yeung R, Weiss SW, Arbiser ZK, Amin MB, Cohen C, Frank D, Mahajan S, Herron GS, Yang J et al. 2001 The generation and characterization of a cell line derived from a sporadic renal angiomyolipoma: use of telomerase to obtain stable populations of cells from benign neoplasms. American Journal of Pathology 159 483-491.
2. Babiker FA, Lips DJ, Delvaux E, Zandberg P, Janssen BJA, Prinzen F, van Eys G, Grohe C & Doevendans PA 2007 Oestrogen modulates cardiac ischaemic remodelling through oestrogen receptor-specific mechanisms. Acta Physiologica 189 23-31.
3. Bissler J & Kingswood J 2004 Renal angiomyolipomata. Kidney International 66 924-934.
4. Boorjian SA, Sheinin Y, Crispen PL, Lohse CM, Kwon ED & Leibovich BC 2008 Hormone receptor expression in renal angiomyolipoma: clinicopathologic correlation. Urology 2 927-932.
5. Casper KA, Donnelly LF, Chen B & Bissler JJ 2002 Tuberous sclerosis complex: renal imaging findings. Radiology 225 451-456.
6. Chandar N, Saluja R, Lamar P, Kolman K & Prozialeck W 2008 P53 and beta-catenin activity during estrogen treatment of osteoblasts. Cancer Cell International 5 25-36.
7. Craigon DJ, James N, Okyere J, Higgins J, Jotham J & May S 2004 NASCArrays: a repository for microarray data generated by NASC's transcriptomics service. Nucleic Acids Research 32 D575-D577.
8. El-Hashemite N, Zhang H, Henske EP & Kwiatkowski DJ 2003 Mutation in TSC2 and activation of mammalian target of rapamycin signalling pathway in renal angiomyolipoma. Lancet 361 1348-1349.
9. El-Hashemite N, Walker V & Kwiatkowski DJ 2005 Estrogen enhances whereas tamoxifen retards development of Tsc mouse liver hemangioma: a tumor related to renal angiomyolipoma and pulmonary lymphangioleiomyomatosis. Cancer Research 65 2474-2481.
10. Ewalt DH, Sheffield E, Sparagana SP, Delgado MR & Roach ES 1998 Renal lesion growth in children with tuberous sclerosis complex. Journal of Urology 160 141-145.
11. Finlay GA, York B, Karas RH, Fanburg BL, Zhang H, Kwiatkowski DJ & Noonan DJ 2004 Estrogen-induced smooth muscle cell growth is regulated by tuberin and associated with altered activation of platelet-derived growth factor receptor-β and ERK-1/2. Journal of Biological Chemistry 279 23114-23122.
12. Franz DN, Brody A, Meyer C, Leonard J, Chuck G, Dabora S, Sethuraman G, Colby TV, Kwiatkowski DJ & McCormack FX 2001 Mutational and radiographic analysis of pulmonary disease consistent with lymphangioleiomyomatosis and micronodular pneumocyte hyperplasia in women with tuberous sclerosis. American Journal of Respiratory and Critical Care Medicine 164 661-668.
13. Frasor J, Danes JM, Komm B, Chang KC, Lyttle CR & Katzenellenbogen BS 2003 Profiling of estrogen up- and down-regulated gene expression in human breast cancer cells: insights into gene networks and pathways underlying estrogenic control of proliferation and cell phenotype. Endocrinology 144 4562-4574.
14. Freyer AM, Johnson SR & Hall IP 2001 Effects of growth factors and extracellular matrix on survival of human airway smooth muscle cells. American Journal of Respiratory Cell and Molecular Biology 25 569-576.
15. Goncharova EA, Goncharov DA, Eszterhas A, Hunter DS, Glassberg MK, Yeung RS, Walker CL, Noonan D, Kwiatkowski DJ, Chou MM et al. 2002 Tuberin regulates p70 S6 kinase activation and ribosomal protein S6 phosphorylation. A role for the TSC2 tumor suppressor gene in pulmonary lymphangioleiomyomatosis (LAM). Journal of Biological Chemistry 277 30958-30967.
16. Harari S, Cassandro R, Chiodini J, Taveira-DaSilva AM & Moss J 2008 Effect of a gonadotrophin-releasing hormone analogue on lung function in lymphangioleiomyomatosis. Chest 133 448-454.
17. Harvell DME, Richer JK, Allred DC, Sartorius CA & Horwitz KB 2006 Estradiol regulates different genes in human breast tumor xenografts compared with the identical cells in culture. Endocrinology 147 700-713.
18. Haslam SZ & Woodward TL 2001 Tumour-stromal interactions: reciprocal regulation of extracellular matrix proteins and ovarian steroid activity in the mammary gland. Breast Cancer Research 3 365-372.
19. Hornick JL & Fletcher CD 2006 PEComa: what do we know so far? Histopathology 48 75-82.
20. Johnson S & Knox A 1999 Autocrine production of matrix metalloproteinase-2 is required for human airway smooth muscle proliferation. American Journal of Physiology 277 L1109-L1117.
21. Johnson SR & Tattersfield AE 1999 Decline in lung function in lymphangioleiomyomatosis: relation to menopause and progesterone treatment. American Journal of Respiratory and Critical Care Medicine 160 628-633.
22. Johnson SR & Tattersfield AE 2000 Clinical experience of lymphangioleiomyomatosis in the UK. Thorax 55 1052-1057.
23. Karbowniczek M, Cash T, Cheung M, Robertson GP, Astrinidis A & Henske EP 2004 Regulation of B-Raf kinase activity by Tuberin and Rheb is mammalian target of rapamycin (mTOR)-independent. Journal of Biological Chemistry 279 29930-29937.
24. Kirkegaard T, Witton CJ, McGlynn LM, Tovey SM, Dunne B, Lyon A & Bartlett JM 2005 AKT activation predicts outcome in breast cancer patients treated with tamoxifen. Journal of Pathology 207 139-146.
25. Kobayashi T, Minowa O, Sugitani Y, Takai S, Mitani H, Kobayashi E, Noda T & Hino O 2001 A germ-line Tsc1 mutation causes tumor development and embryonic lethality that are similar, but not identical to, those caused by Tsc2 mutation in mice. PNAS 98 8762-8767.
26. L'Hostis H, Deminiere C, Ferriere JM & Coindre JM 1999 Renal angiomyolipoma: a clinicopathologic, immunohistochemical, and follow-up study of 46 cases. American Journal of Surgical Pathology 23 1011-1020.
27. Lesma E, Grande V, Carelli S, Brancaccio D, Canevini MP, Alfano RM, Coggi G, Di Giulio AM & Gorio A 2005 Isolation and growth of smooth muscle-like cells derived from tuberous sclerosis complex-2 human renal angio-myolipoma: epidermal growth factor is the required growth factor. American Journal of Pathology 167 1093-1103.
28. Li Y, Corradetti MN, Inoki K & Guan K-L 2004 TSC2: filling the GAP in the mTOR signaling pathway. Trends in Biochemical Sciences 29 32-38.
29. Lin CY, Strom A, Vega VB, Kong SL, Yeo AL, Thomsen JS, Chan WC, Doray B, Bangarusamy DK, Ramasamy A et al. 2004 Discovery of estrogen receptor alpha target genes and response elements in breast tumor cells. Genome Biology 5 R66.
30. Logginidou H, Ao X, Russo I & Henske EP 2000 Frequent estrogen and progesterone receptor immunoreactivity in renal angiomyolipomas from women with pulmonary lymphangioleiomyomatosis. Chest 117 25-30.
31. Matsui K, Takeda K, Yu ZX, Valencia J, Travis WD, Moss J & Ferrans VJ 2000 Downregulation of estrogen and progesterone receptors in the abnormal smooth muscle cells in pulmonary lymphangioleiomyomatosis following therapy. An immunohistochemical study. American Journal of Respiratory and Critical Care Medicine 161 1002-1009.
32. Onda H, Lueck A, Marks PW, Warren HB & Kwiatkowski DJ 1999 Tsc2(+/ -)mice develop tumors inmultiple sites that express gelsolin and are influenced by genetic background. Journal of Clinical Investigation 104 687-695.
33. Pea M, Martignoni G, Bonetti F, Zamboni G, Colombari C, Manfrin E, Lestani M, Mombello A & Mariuzzi GM 1997 Tumors characterized by the presence of HMB45-positive perivascular epithelioid cell (PEC) - a novel entity in surgical pathology. Electronic Journal of Pathology and Histology 3 28-40.
34. Reigstad LJ, Varhaug JE & Lillehaug JR 2005 Structural and functional specificities of PDGF-C and PDGF-D, the novel members of the platelet-derived growth factors family. FEBS Journal 272 5723-5741.
35. Roma A, Magi-Galluzzi C & Zhou M 2007 Differential expression of melanocytic markers in myoid, lipomatous, and vascular components of renal angiomyolipomas. Archives of Pathology & Laboratory Medicine 131 122-125.
36. Ross DT & Perou CM 2001 A comparison of gene expression signatures from breast tumors and breast tissue derived cell lines. Disease Markers 17 99-109.
37. Sullivan EJ 1998 Lymphangioleiomyomatosis: a review. Chest 114 1689-1703.
38. Testa JR & Bellacosa A 2001 AKT plays a central role in tumorigenesis. PNAS 98 10983-10985.
39. Tsai EM, Wang SC, Lee JN & Hung MC 2001 Akt activation by estrogen in estrogen receptor-negative breast cancer cells. Cancer Research 61 8390-8392.
40. Uutela M, Lauren J, Bergsten E, Li X, Horelli-Kuitunen N, Eriksson U & Alitalo K 2001 Chromosomal location, exon structure, and vascular expression patterns of the human PDGFC and PDGFD genes. Circulation 103 2242-2247.
41. Wilson C, Idziaszczyk S, Parry L, Guy C, Griffiths DFR, Lazda E, Bayne RAL, Smith AJH, Sampson JR & Cheadle JP 2005 A mouse model of tuberous sclerosis 1 showing background specific early post-natal mortality and metastatic renal cell carcinoma. Human Molecular Genetics 14 1839-1850.
42. Yeung RS, Xiao GH, Jin F, Lee WC, Testa JR & Knudson AG 1994 Predisposition to renal carcinoma in the Eker rat is determined by germ-line mutation of the tuberous sclerosis 2 (TSC2) gene. PNAS 91 11413-11416.
43. Yu J & Henske EP 2006 Estrogen-induced activation of mammalian target of rapamycin is mediated via tuberin and the small GTPase Ras homologue enriched in brain. Cancer Research 66 9461-9466.
44. Yu J, Astrinidis A, Howard S & Henske EP 2004 Estradiol and tamoxifen stimulate LAM-associated angiomyolipoma cell growth and activate both genomic and nongenomic signaling pathways. American Journal of Physiology. Lung Cellular and Molecular Physiology 286 L694-L700.