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Volumn 51, Issue 1, 2009, Pages 57-63

Di-(2-ethylhexyl) phthalate upregulates ATF3 expression and suppresses apoptosis in mouse genital tubercle

Author keywords

Activating transcription factor 3; Apoptosis; Di (2 ethylhexyl) phthalate; Hypospadias; Mouse

Indexed keywords

MUS; ZEA MAYS;

EID: 65549157630     PISSN: 13419145     EISSN: 13489585     Source Type: Journal    
DOI: 10.1539/joh.L8091     Document Type: Article
Times cited : (15)

References (31)
  • 1
    • 0030002143 scopus 로고    scopus 로고
    • Hepatocarcinogenic potential of di(2-ethylhexyl) phthalate in rodents and its implications on human risk
    • Huber WW, Grasl-Kraupp B, Schulte-Hermann R. Hepatocarcinogenic potential of di(2-ethylhexyl) phthalate in rodents and its implications on human risk. Crit Rev Toxicol 1996; 26: 365-481.
    • (1996) Crit Rev Toxicol , vol.26 , pp. 365-481
    • Huber, W.W.1    Grasl-Kraupp, B.2    Schulte-Hermann, R.3
  • 2
    • 0037772270 scopus 로고    scopus 로고
    • Pathogenesis of male reproductive tract lesions from gestation through adulthood following in utero exposure to Di(n-butyl) phthalate
    • Barlow NJ, Foster PM. Pathogenesis of male reproductive tract lesions from gestation through adulthood following in utero exposure to Di(n-butyl) phthalate. Toxicol Pathol 2003; 31: 397-410.
    • (2003) Toxicol Pathol , vol.31 , pp. 397-410
    • Barlow, N.J.1    Foster, P.M.2
  • 3
    • 33645231471 scopus 로고    scopus 로고
    • Di(2-ethylhexyl)phthalate (DEHP): human metabolism and internal exposure-an update and latest results
    • Koch HM, Preuss R, Angerer J. Di(2-ethylhexyl)phthalate (DEHP): human metabolism and internal exposure-an update and latest results. Int J Androl 2006; 29: 155-65.
    • (2006) Int J Androl , vol.29 , pp. 155-165
    • Koch, H.M.1    Preuss, R.2    Angerer, J.3
  • 4
    • 0037977838 scopus 로고    scopus 로고
    • Pediatric exposure and potential toxicity of phthalate plasticizers
    • Shea KM. Pediatric exposure and potential toxicity of phthalate plasticizers. Pediatrics 2003; 111: 1467-74.
    • (2003) Pediatrics , vol.111 , pp. 1467-1474
    • Shea, K.M.1
  • 5
    • 45149090152 scopus 로고    scopus 로고
    • Effects of diethylhexyl phthalate (DEHP) on INSL3 mRNA expression by Leydig cells derived from mouse embryos and in newborn mice
    • Song XF, Wei GH, Liu X, Zhang DY, Chen X, Deng YJ. Effects of diethylhexyl phthalate (DEHP) on INSL3 mRNA expression by Leydig cells derived from mouse embryos and in newborn mice. J Int Med Res 2008; 36: 512-21.
    • (2008) J Int Med Res , vol.36 , pp. 512-521
    • Song, X.F.1    Wei, G.H.2    Liu, X.3    Zhang, D.Y.4    Chen, X.5    Deng, Y.J.6
  • 6
    • 49449114692 scopus 로고    scopus 로고
    • Di(2-Ethylhexyl) phthalate (DEHP) increases transforming growth factor-β1 expression in fetal mouse genital tubercles
    • Liu X, He DW, Zhang DY, Lin T, Wei GH. Di(2-Ethylhexyl) phthalate (DEHP) increases transforming growth factor-β1 expression in fetal mouse genital tubercles. J Toxicol Environ Health, Part A 2008; 71: 1289-94.
    • (2008) J Toxicol Environ Health, Part A , vol.71 , pp. 1289-1294
    • Liu, X.1    He, D.W.2    Zhang, D.Y.3    Lin, T.4    Wei, G.H.5
  • 7
    • 0035948624 scopus 로고    scopus 로고
    • The molecular biology and nomenclature of the activating transcription factor/cAMP responsive element binding family of transcription factors: activating transcription factor proteins and homeostasis
    • Hai T, Hartman MG. The molecular biology and nomenclature of the activating transcription factor/cAMP responsive element binding family of transcription factors: activating transcription factor proteins and homeostasis. Gene 2001; 273: 1-11.
    • (2001) Gene , vol.273 , pp. 1-11
    • Hai, T.1    Hartman, M.G.2
  • 8
    • 0036803020 scopus 로고    scopus 로고
    • Development of cDNA microarray for expression profiling of estrogen-responsive genes
    • Inoue A, Yoshida N, Omoto Y, et al. Development of cDNA microarray for expression profiling of estrogen-responsive genes. J Mol Endocrinol 2002; 29: 175-92.
    • (2002) J Mol Endocrinol , vol.29 , pp. 175-192
    • Inoue, A.1    Yoshida, N.2    Omoto, Y.3
  • 9
    • 0141866865 scopus 로고    scopus 로고
    • Amino acid deprivation and endoplasmic reticulum stress induce expression of multiple activating transcription factor-3 mRNA species that when overexpressed in HepG2 cells, modulate transcription by the human asparagine synthetase promoter
    • Pan Y, Chen H, Siu F, Kilberg MS. Amino acid deprivation and endoplasmic reticulum stress induce expression of multiple activating transcription factor- 3 mRNA species that when overexpressed in HepG2 cells, modulate transcription by the human asparagine synthetase promoter. J Biol Chem 2003; 278: 38402-12.
    • (2003) J Biol Chem , vol.278 , pp. 38402-38412
    • Pan, Y.1    Chen, H.2    Siu, F.3    Kilberg, M.S.4
  • 10
    • 43149103366 scopus 로고    scopus 로고
    • Activating transcription factor 3: a hormone responsive gene in the etiology of hypospadias
    • Beleza-Meireles A, Töhönen V, Söderhäll C, et al. Activating transcription factor 3: a hormone responsive gene in the etiology of hypospadias. Eur J Endocrinol 2008; 158: 729-39.
    • (2008) Eur J Endocrinol , vol.158 , pp. 729-739
    • Beleza-Meireles, A.1    Töhönen, V.2    Söderhäll, C.3
  • 11
    • 33644772229 scopus 로고    scopus 로고
    • Activating transcription factor 3 is up-regulated in patients with hypospadias
    • Liu B, Wang Z, Lin G, et al. Activating transcription factor 3 is up-regulated in patients with hypospadias. Pediatr Res 2005; 58: 1280-3.
    • (2005) Pediatr Res , vol.58 , pp. 1280-1283
    • Liu, B.1    Wang, Z.2    Lin, G.3
  • 12
    • 33646088731 scopus 로고    scopus 로고
    • Activating transcription factor 3 is estrogen-responsive in utero and upregulated during sexual differentiation
    • Liu B, Agras K, Willingham E, Vilela ML, Baskin LS. Activating transcription factor 3 is estrogen-responsive in utero and upregulated during sexual differentiation. Horm Res 2006; 65: 217-22.
    • (2006) Horm Res , vol.65 , pp. 217-222
    • Liu, B.1    Agras, K.2    Willingham, E.3    Vilela, M.L.4    Baskin, L.S.5
  • 13
    • 37349069521 scopus 로고    scopus 로고
    • Estradiol upregulates activating transcription factor 3, a candidate gene in the etiology of hypospadias
    • Liu B, Lin G, Willingham E, et al. Estradiol upregulates activating transcription factor 3, a candidate gene in the etiology of hypospadias. Pediatr Dev Pathol 2007; 10: 446-54.
    • (2007) Pediatr Dev Pathol , vol.10 , pp. 446-454
    • Liu, B.1    Lin, G.2    Willingham, E.3
  • 14
    • 34248581290 scopus 로고    scopus 로고
    • Candidate genes and their response to environmental agents in the etiology of hypospadias
    • Willingham E, Baskin LS. Candidate genes and their response to environmental agents in the etiology of hypospadias. Nat Clin Pract Urol 2007; 4: 270-9.
    • (2007) Nat Clin Pract Urol , vol.4 , pp. 270-579
    • Willingham, E.1    Baskin, L.S.2
  • 18
    • 8444237811 scopus 로고    scopus 로고
    • Phthalates inhibit tamoxifen- induced apoptosis in MCF-7 human breast cancer cells
    • Kim IY, Han SY, Moon A. Phthalates inhibit tamoxifen-induced apoptosis in MCF-7 human breast cancer cells. J Toxicol Environ Health, Part A 2004; 67: 2025-35.
    • (2004) J Toxicol Environ Health, Part A , vol.67 , pp. 2025-2035
    • Kim, I.Y.1    Han, S.Y.2    Moon, A.3
  • 19
    • 23044502608 scopus 로고    scopus 로고
    • Di-(2-ethylhexyl)phthalate (DEHP) increases Bcl-2/Bax ratio and modifies c-myc expression in Syrian hamster embryo (SHE) cells
    • Maire MA, Rast C, Vasseur P. Di-(2-ethylhexyl)phthalate (DEHP) increases Bcl-2/Bax ratio and modifies c-myc expression in Syrian hamster embryo (SHE) cells. Toxicol Lett 2005; 158: 237-45.
    • (2005) Toxicol Lett , vol.158 , pp. 237-245
    • Maire, M.A.1    Rast, C.2    Vasseur, P.3
  • 20
    • 0036208139 scopus 로고    scopus 로고
    • DI-(2-ethylhexyl) phthalate-induced cell proliferation is involved in the inhibition of gap junctional intercellular communication and blockage of apoptosis in mouse Sertoli cells
    • Kang KS, Lee YS, Kim HS, Kim SH. DI-(2-ethylhexyl) phthalate-induced cell proliferation is involved in the inhibition of gap junctional intercellular communication and blockage of apoptosis in mouse Sertoli cells. J Toxicol Environ Health, Part A 2002; 65: 447-59.
    • (2002) J Toxicol Environ Health, Part A , vol.65 , pp. 447-459
    • Kang, K.S.1    Lee, Y.S.2    Kim, H.S.3    Kim, S.H.4
  • 21
    • 0343090362 scopus 로고    scopus 로고
    • Administration of potentially antiandrogenic pesticides (procymidone, linuron, iprodione, chlozolinate, p,p'-DDE, and ketoconazole) and toxic substances (dibutyl- and diethylhexyl phthalate, PCB 169, and ethane dimethane sulphonate) during sexual differentiation produces diverse profiles of reproductive malformations in the male rat
    • Gray LE Jr, Wolf C, Lambright C, et al. Administration of potentially antiandrogenic pesticides (procymidone, linuron, iprodione, chlozolinate, p,p'-DDE, and ketoconazole) and toxic substances (dibutyl- and diethylhexyl phthalate, PCB 169, and ethane dimethane sulphonate) during sexual differentiation produces diverse profiles of reproductive malformations in the male rat. Toxicol Ind Health 1999; 15: 94-118.
    • (1999) Toxicol Ind Health , vol.15 , pp. 94-118
    • Gray L.E., Jr.1    Wolf, C.2    Lambright, C.3
  • 22
    • 0033010382 scopus 로고    scopus 로고
    • Disruption of androgen-regulated male reproductive development by di(n-butyl) phthalate during late gestation in rats is different from flutamide
    • Mylchreest E, Sar M, Cattley RC, Foster PM. Disruption of androgen-regulated male reproductive development by di(n-butyl) phthalate during late gestation in rats is different from flutamide. Toxicol Appl Pharmacol 1999; 156: 81-95.
    • (1999) Toxicol Appl Pharmacol , vol.156 , pp. 81-95
    • Mylchreest, E.1    Sar, M.2    Cattley, R.C.3    Foster, P.M.4
  • 23
    • 0035199253 scopus 로고    scopus 로고
    • Hypospadias and endocrine disruption: is there a connection?
    • Baskin LS, Himes K, Colborn T. Hypospadias and endocrine disruption: is there a connection? Environ Health Perspect 2001; 109: 1175-83.
    • (2001) Environ Health Perspect , vol.109 , pp. 1175-1183
    • Baskin, L.S.1    Himes, K.2    Colborn, T.3
  • 24
    • 0041669549 scopus 로고    scopus 로고
    • Loss of Bmp7 and Fgf8 signaling in Hoxa13-mutant mice causes hypospadia
    • Morgan EA, Nguyen SB, Scott V, Stadler HS. Loss of Bmp7 and Fgf8 signaling in Hoxa13-mutant mice causes hypospadia. Development 2003; 130: 3095-109.
    • (2003) Development , vol.130 , pp. 3095-3109
    • Morgan, E.A.1    Nguyen, S.B.2    Scott, V.3    Stadler, H.S.4
  • 25
    • 10744226161 scopus 로고    scopus 로고
    • Regulation of outgrowth and apoptosis for the terminal appendage: external genitalia development by concerted actions of BMP signaling
    • Suzuki K, Bachiller D, Chen YP, et al. Regulation of outgrowth and apoptosis for the terminal appendage: external genitalia development by concerted actions of BMP signaling. Development 2003; 130: 6209-20.
    • (2003) Development , vol.130 , pp. 6209-6220
    • Suzuki, K.1    Bachiller, D.2    Chen, Y.P.3
  • 26
    • 2342655674 scopus 로고    scopus 로고
    • Over expression of ATF-3 protects rat hippocampal neurons from in vivo injection of kainic acid
    • Francis JS, Dragunow M, During MJ. Over expression of ATF-3 protects rat hippocampal neurons from in vivo injection of kainic acid. Brain Res Mol Brain Res 2004; 124: 199-203.
    • (2004) Brain Res Mol Brain Res , vol.124 , pp. 199-203
    • Francis, J.S.1    Dragunow, M.2    During, M.J.3
  • 28
    • 0036772883 scopus 로고    scopus 로고
    • ATF3 inhibits doxorubicin-induced apoptosis in cardiac myocytes: a novel cardioprotective role of ATF3
    • Nobori K, Ito H, Tamamori-Adachi M, et al. ATF3 inhibits doxorubicin-induced apoptosis in cardiac myocytes: a novel cardioprotective role of ATF3. J Mol Cell Cardiol 2002; 34: 1387-97.
    • (2002) J Mol Cell Cardiol , vol.34 , pp. 1387-1397
    • Nobori, K.1    Ito, H.2    Tamamori-Adachi, M.3
  • 29
    • 0037192831 scopus 로고    scopus 로고
    • ATF3 represses 72-kDa type IV collagenase (MMP-2) expression by antagonizing p53-dependent transactivation of the collagenase promoter
    • Yan C, Wang H, Boyd DD. ATF3 represses 72-kDa type IV collagenase (MMP-2) expression by antagonizing p53-dependent transactivation of the collagenase promoter. J Biol Chem 2002; 277: 10804-12.
    • (2002) J Biol Chem , vol.277 , pp. 10804-10812
    • Yan, C.1    Wang, H.2    Boyd, D.D.3
  • 30
    • 0037064094 scopus 로고    scopus 로고
    • Transcriptional repressor activating transcription factor 3 protects human umbilical vein endothelial cells from tumor necrosis factor-alpha-induced apoptosis through down-regulation of p53 transcription
    • Kawauchi J, Zhang C, Nobori K, et al. Transcriptional repressor activating transcription factor 3 protects human umbilical vein endothelial cells from tumor necrosis factor-alpha-induced apoptosis through down-regulation of p53 transcription. J Biol Chem 2002; 277: 39025-34.
    • (2002) J Biol Chem , vol.277 , pp. 39025-39034
    • Kawauchi, J.1    Zhang, C.2    Nobori, K.3
  • 31
    • 0027166048 scopus 로고
    • Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death
    • Oltvai ZN, Milliman CL, Korsmeyer SJ. Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell 1993; 74: 609-19.
    • (1993) Cell , vol.74 , pp. 609-619
    • Oltvai, Z.N.1    Milliman, C.L.2    Korsmeyer, S.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.