Genetics and cell biology: A promoter polymorphism in the ALDH2 gene affects its basal and acetaldehyde/ethanol-induced gene expression in human peripheral blood leukocytes and HepG2 cells

Alcohol and Alcoholism

Volumn 44, Issue 3, 2009, Pages 261-266

  Kimura, Yukiko ^a   Nishimura, Fusae T ^a   Abe, Shuntaro ^b   Fukunaga, Tatsushige ^c   Tanii, Hideji ^a   Saijoh, Kiyofumi ^a  

^a KANAZAWA UNIVERSITY GRADUATE SCHOOL OF MEDICAL SCIENCE   (Japan)

^b JIKEI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c Tokyo Medical Examiner's Office   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACETALDEHYDE; ALCOHOL; ALDEHYDE DEHYDROGENASE ISOENZYME 2; GLUTAMIC ACID; LYSINE; MESSENGER RNA; ALDEHYDE DEHYDROGENASE; ALDH2 PROTEIN, HUMAN;

ADULT; ALCOHOL BLOOD LEVEL; ALCOHOL CONSUMPTION; ALCOHOL METABOLISM; ALLELE; ARTICLE; CELL ISOLATION; CELL STRAIN HEPG2; CONTROLLED STUDY; DIET RESTRICTION; GAS CHROMATOGRAPHY; GENE EXPRESSION; GENETIC POLYMORPHISM; GENETIC TRANSCRIPTION; GENOTYPE; HETEROZYGOSITY; HOMOZYGOSITY; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; IN VITRO STUDY; IN VIVO STUDY; JAPANESE; LEUKOCYTE; MALE; NORMAL HUMAN; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VOLUNTEER; BLOOD; COMPARATIVE STUDY; DRINKING BEHAVIOR; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MONONUCLEAR CELL; PHYSIOLOGY; TUMOR CELL LINE;

ACETALDEHYDE; ALCOHOL DRINKING; ALDEHYDE DEHYDROGENASE; CELL LINE, TUMOR; ETHANOL; GENE EXPRESSION REGULATION; HUMANS; LEUKOCYTES, MONONUCLEAR; MALE; POLYMORPHISM, GENETIC; PROMOTER REGIONS, GENETIC; YOUNG ADULT;

EID: 65549157575     PISSN: 07350414     EISSN: 14643502     Source Type: Journal    
DOI: 10.1093/alcalc/agn123     Document Type: Article

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