-
1
-
-
13044256383
-
A small-molecule, nonpeptide CCR5 antagonist with highly potent and selective anti-HIV-1 activity
-
Baba, M., O. Nishimura, N. Kanzaki, M. Okamoto, H. Sawada, Y. Iizawa, M. Shiraishi, Y. Aramaki, K. Okonogi, Y. Ogawa, K. Meguro, and M. Fujino. 1999. A small-molecule, nonpeptide CCR5 antagonist with highly potent and selective anti-HIV-1 activity. Proc. Natl. Acad. Sci. USA 96:5698-5703.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 5698-5703
-
-
Baba, M.1
Nishimura, O.2
Kanzaki, N.3
Okamoto, M.4
Sawada, H.5
Iizawa, Y.6
Shiraishi, M.7
Aramaki, Y.8
Okonogi, K.9
Ogawa, Y.10
Meguro, K.11
Fujino, M.12
-
2
-
-
1842415431
-
Coreceptor usage of primary human immunodeficiency virus type 1 isolates varies according to biological phenotype
-
Bjorndal, A., H. Deng, M. Jansson, J. R. Fiore, C. Colognesi, A. Karlsson, J. Albert, G. Scarlatti, D. R. Littman, and E. M. Fenyo. 1997. Coreceptor usage of primary human immunodeficiency virus type 1 isolates varies according to biological phenotype. J. Virol. 71:7478-7487.
-
(1997)
J. Virol.
, vol.71
, pp. 7478-7487
-
-
Bjorndal, A.1
Deng, H.2
Jansson, M.3
Fiore, J.R.4
Colognesi, C.5
Karlsson, A.6
Albert, J.7
Scarlatti, G.8
Littman, D.R.9
Fenyo, E.M.10
-
3
-
-
11144357239
-
Mouse model of cervicovaginal toxicity and inflammation for preclinical evaluation of topical vaginal microbicides
-
Catalone, B. J., T. M. Kish-Catalone, L. R. Budgeon, E. B. Neely, M. Ferguson, F. C. Krebs, M. K. Howett, M. Labib, R. Rando, and B. Wigdahl. 2004. Mouse model of cervicovaginal toxicity and inflammation for preclinical evaluation of topical vaginal microbicides. Antimicrob. Agents Chemother. 48:1837-1847.
-
(2004)
Antimicrob. Agents Chemother.
, vol.48
, pp. 1837-1847
-
-
Catalone, B.J.1
Kish-Catalone, T.M.2
Budgeon, L.R.3
Neely, E.B.4
Ferguson, M.5
Krebs, F.C.6
Howett, M.K.7
Labib, M.8
Rando, R.9
Wigdahl, B.10
-
4
-
-
2542437933
-
Candidate topical microbicides bind herpes simplex virus glycoprotein B and prevent viral entry and cell-to-cell spread
-
Cheshenko, N., M. J. Keller, V. MasCasullo, G. A. Jarvis, H. Cheng, M. John, J. H. Li, K. Hogarty, R. A. Anderson, D. P. Waller, L. J. Zaneveld, A. T. Profy, M. E. Klotman, and B. C. Herold. 2004. Candidate topical microbicides bind herpes simplex virus glycoprotein B and prevent viral entry and cell-to-cell spread. Antimicrob. Agents Chemother. 48:2025-2036.
-
(2004)
Antimicrob. Agents Chemother.
, vol.48
, pp. 2025-2036
-
-
Cheshenko, N.1
Keller, M.J.2
MasCasullo, V.3
Jarvis, G.A.4
Cheng, H.5
John, M.6
Li, J.H.7
Hogarty, K.8
Anderson, R.A.9
Waller, D.P.10
Zaneveld, L.J.11
Profy, A.T.12
Klotman, M.E.13
Herold, B.C.14
-
5
-
-
0034530226
-
Preliminary safety and acceptability of a carrageenan gel for possible use as a vaginal microbicide
-
Coggins, C., K. Blanchard, F. Alvarez, V. Brache, E. Weisberg, P. H. Kilmarx, M. Lacarra, R. Massai, D. J. Mishell, A. Salvatierra, P. Witwatwongwana, C. Elias, and C. Ellertson. 2000. Preliminary safety and acceptability of a carrageenan gel for possible use as a vaginal microbicide. Sex. Transm. Infect. 76:480-483.
-
(2000)
Sex. Transm. Infect.
, vol.76
, pp. 480-483
-
-
Coggins, C.1
Blanchard, K.2
Alvarez, F.3
Brache, V.4
Weisberg, E.5
Kilmarx, P.H.6
Lacarra, M.7
Massai, R.8
Mishell, D.J.9
Salvatierra, A.10
Witwatwongwana, P.11
Elias, C.12
Ellertson, C.13
-
6
-
-
4644225675
-
In vitro comparison of topical microbicides for prevention of human immunodeficiency virus type 1 transmission
-
Dezzutti, C. S., V. N. James, A. Ramos, S. T. Sullivan, A. Siddig, T. J. Bush, L. A. Grohskopf, L. Paxton, S. Subbarao, and C. E. Hart. 2004. In vitro comparison of topical microbicides for prevention of human immunodeficiency virus type 1 transmission. Antimicrob. Agents Chemother. 48:3834-3844.
-
(2004)
Antimicrob. Agents Chemother.
, vol.48
, pp. 3834-3844
-
-
Dezzutti, C.S.1
James, V.N.2
Ramos, A.3
Sullivan, S.T.4
Siddig, A.5
Bush, T.J.6
Grohskopf, L.A.7
Paxton, L.8
Subbarao, S.9
Hart, C.E.10
-
7
-
-
0034625144
-
A binding pocket for a small molecule inhibitor of HIV-1 entry within the transmembrane helices of CCR5
-
Dragic, T., A. Trkola, D. A. Thompson, E. G. Cormier, F. A. Kajumo, E. Maxwell, S. W. Lin, W. Ying, S. O. Smith, T. P. Sakmar, and J. P. Moore. 2000. A binding pocket for a small molecule inhibitor of HIV-1 entry within the transmembrane helices of CCR5. Proc. Natl. Acad. Sci. USA 97:5639-5644.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 5639-5644
-
-
Dragic, T.1
Trkola, A.2
Thompson, D.A.3
Cormier, E.G.4
Kajumo, F.A.5
Maxwell, E.6
Lin, S.W.7
Ying, W.8
Smith, S.O.9
Sakmar, T.P.10
Moore, J.P.11
-
8
-
-
0031426560
-
Colposcopic evaluation of a vaginal gel formulation of iota-carrageenan
-
Elias, C. J., C. Coggins, F. Alvarez, V. Brache, I. S. Fraser, M. Lacarra, P. Lahteenmaki, R. Massai, D. R. J. Mishell, D. M. Phillips, and A. M. Salvatierra. 1997. Colposcopic evaluation of a vaginal gel formulation of iota-carrageenan. Contraception 56:387-389.
-
(1997)
Contraception
, vol.56
, pp. 387-389
-
-
Elias, C.J.1
Coggins, C.2
Alvarez, F.3
Brache, V.4
Fraser, I.S.5
Lacarra, M.6
Lahteenmaki, P.7
Massai, R.8
Mishell, D.R.J.9
Phillips, D.M.10
Salvatierra, A.M.11
-
9
-
-
0034034688
-
Parameters of human immunodeficiency virus infection of human cervical tissue and inhibition by vaginal virucides
-
Greenhead, P., P. Hayes, P. S. Watts, K. G. Laing, G. E. Griffin, and R. J. Shattock. 2000. Parameters of human immunodeficiency virus infection of human cervical tissue and inhibition by vaginal virucides. J. Virol. 74:5577-5586.
-
(2000)
J. Virol.
, vol.74
, pp. 5577-5586
-
-
Greenhead, P.1
Hayes, P.2
Watts, P.S.3
Laing, K.G.4
Griffin, G.E.5
Shattock, R.J.6
-
11
-
-
0036827915
-
Mandelic acid condensation polymer: Novel candidate microbicide for prevention of human immunodeficiency virus and herpes simplex virus entry
-
Herold, B. C., I. Scordi-Bello, N. Cheshenko, D. Marcellino, M. Dzuzelewski, F. Francois, R. Morin, V. M. Casullo, R. A. Anderson, C. Chany II, D. P. Waller, L. J. D. Zaneveld, and M. E. Klotman. 2002. Mandelic acid condensation polymer: novel candidate microbicide for prevention of human immunodeficiency virus and herpes simplex virus entry. J. Virol. 76:11236-11244.
-
(2002)
J. Virol.
, vol.76
, pp. 11236-11244
-
-
Herold, B.C.1
Scordi-Bello, I.2
Cheshenko, N.3
Marcellino, D.4
Dzuzelewski, M.5
Francois, F.6
Morin, R.7
Casullo, V.M.8
Anderson, R.A.9
Chany II, C.10
Waller, D.P.11
Zaneveld, L.J.D.12
Klotman, M.E.13
-
12
-
-
0022311629
-
Inactivation of HTLV-III/ LAV-infected cultures of normal human lymphocytes by nonoxynol-9 in vitro
-
Hicks, D. R., L. S. Martin, J. P. Getchell, J. L. Heath, D. P. Francis, J. S. McDougal, J. W. Curran, and B. Voeller. 1985. Inactivation of HTLV-III/ LAV-infected cultures of normal human lymphocytes by nonoxynol-9 in vitro. Lancet ii:1422-1423.
-
(1985)
Lancet
, vol.2
, pp. 1422-1423
-
-
Hicks, D.R.1
Martin, L.S.2
Getchell, J.P.3
Heath, J.L.4
Francis, D.P.5
McDougal, J.S.6
Curran, J.W.7
Voeller, B.8
-
13
-
-
2442428094
-
Blockade of attachment and fusion receptors inhibits HIV-1 infection of human cervical tissue
-
Hu, Q., I. Frank, V. Williams, J. J. Santos, P. Watts, G. E. Griffin, J. P. Moore, M. Pope, and R. J. Shattock. 2004. Blockade of attachment and fusion receptors inhibits HIV-1 infection of human cervical tissue. J. Exp. Med. 199:1065-1075.
-
(2004)
J. Exp. Med.
, vol.199
, pp. 1065-1075
-
-
Hu, Q.1
Frank, I.2
Williams, V.3
Santos, J.J.4
Watts, P.5
Griffin, G.E.6
Moore, J.P.7
Pope, M.8
Shattock, R.J.9
-
14
-
-
0030979349
-
Anti-HIV type 1 activity of sulfated derivatives of dextrin against primary viral isolates of HIV type 1 in lymphocytes and monocyte-derived macrophages
-
Javan, C. M., N. J. Gooderham, R. J. Edwards, D. S. Davies, and S. Shaunak. 1997. Anti-HIV type 1 activity of sulfated derivatives of dextrin against primary viral isolates of HIV type 1 in lymphocytes and monocyte-derived macrophages. AIDS Res. Hum. Retrovir. 13:875-880.
-
(1997)
AIDS Res. Hum. Retrovir.
, vol.13
, pp. 875-880
-
-
Javan, C.M.1
Gooderham, N.J.2
Edwards, R.J.3
Davies, D.S.4
Shaunak, S.5
-
15
-
-
0028148319
-
The World Health Organization global programme on AIDS proposal for standardization of HIV sequence nomenclature
-
WHO network for HIV isolation and characterization
-
Korber, B. T., S. Osmanov, J. Esparza, and G. Myers. 1994. The World Health Organization global programme on AIDS proposal for standardization of HIV sequence nomenclature. WHO network for HIV isolation and characterization. AIDS Res. Hum. Retrovir. 10:1355-1358.
-
(1994)
AIDS Res. Hum. Retrovir.
, vol.10
, pp. 1355-1358
-
-
Korber, B.T.1
Osmanov, S.2
Esparza, J.3
Myers, G.4
-
16
-
-
12444285441
-
MIF signal transduction initiated by binding to CD74
-
Leng, L., C. N. Metz, Y. Fang, J. Xu, S. Donnelly, J. Baugh, T. Delohery, Y. Chen, R. A. Mitchell, and R. Bucala. 2003. MIF signal transduction initiated by binding to CD74. J. Exp. Med. 197:1467-1476.
-
(2003)
J. Exp. Med.
, vol.197
, pp. 1467-1476
-
-
Leng, L.1
Metz, C.N.2
Fang, Y.3
Xu, J.4
Donnelly, S.5
Baugh, J.6
Delohery, T.7
Chen, Y.8
Mitchell, R.A.9
Bucala, R.10
-
17
-
-
12144287276
-
Interaction between heptad repeat 1 and 2 regions in spike protein of SARS-associated coronavirus: Implications for virus fusogenic mechanism and identification of fusion inhibitors
-
Liu, S., G. Xiao, Y. Chen, Y. He, J. Niu, C. R. Escalante, H. Xiong, J. Farmar, A. K. Debnath, P. Tien, and S. Jiang. 2004. Interaction between heptad repeat 1 and 2 regions in spike protein of SARS-associated coronavirus: implications for virus fusogenic mechanism and identification of fusion inhibitors. Lancet 363:938-947.
-
(2004)
Lancet
, vol.363
, pp. 938-947
-
-
Liu, S.1
Xiao, G.2
Chen, Y.3
He, Y.4
Niu, J.5
Escalante, C.R.6
Xiong, H.7
Farmar, J.8
Debnath, A.K.9
Tien, P.10
Jiang, S.11
-
18
-
-
0027980669
-
Sulfated polyanions prevent HIV infection of lymphocytes by disruption of the CD4-gp120 interaction, but do not inhibit monocyte infection
-
Lynch, G., L. Low, S. Li, A. Sloane, S. Adams, C. Parish, B. Kemp, and A. L. Cunningham. 1994. Sulfated polyanions prevent HIV infection of lymphocytes by disruption of the CD4-gp120 interaction, but do not inhibit monocyte infection. J. Leukoc. Biol. 56:266-272.
-
(1994)
J. Leukoc. Biol.
, vol.56
, pp. 266-272
-
-
Lynch, G.1
Low, L.2
Li, S.3
Sloane, A.4
Adams, S.5
Parish, C.6
Kemp, B.7
Cunningham, A.L.8
-
19
-
-
0036100526
-
Replication and compartmentalization of HIV-1 in kidney epithelium of patients with HIV-associated nephropathy
-
Marras, D., L. A. Bruggeman, F. Gao, N. Tanji, M. M. Mansukhani, A. Cara, M. D. Ross, G. L. Gusella, G. Benson, V. D. D'Agati, B. H. Hahn, M. E. Klotman, and P. E. Klotman. 2002. Replication and compartmentalization of HIV-1 in kidney epithelium of patients with HIV-associated nephropathy. Nat. Med. 8:522-526.
-
(2002)
Nat. Med.
, vol.8
, pp. 522-526
-
-
Marras, D.1
Bruggeman, L.A.2
Gao, F.3
Tanji, N.4
Mansukhani, M.M.5
Cara, A.6
Ross, M.D.7
Gusella, G.L.8
Benson, G.9
D'Agati, V.D.10
Hahn, B.H.11
Klotman, M.E.12
Klotman, P.E.13
-
20
-
-
0035709299
-
Single and multiple exposure tolerance study of cellulose sulfate gel: A phase I safety and colposcopy study
-
Mauck, C., D. H. Weiner, S. Ballagh, M. Creinin, D. F. Archer, J. Schwartz, H. Pymar, J. J. Lai, and M. Callahan. 2001. Single and multiple exposure tolerance study of cellulose sulfate gel: a phase I safety and colposcopy study. Contraception 64:383-391.
-
(2001)
Contraception
, vol.64
, pp. 383-391
-
-
Mauck, C.1
Weiner, D.H.2
Ballagh, S.3
Creinin, M.4
Archer, D.F.5
Schwartz, J.6
Pymar, H.7
Lai, J.J.8
Callahan, M.9
-
21
-
-
0033920212
-
Selective interactions of polyanions with basic surfaces on human immunodeficiency virus type 1 gp120
-
Moulard, M., H. Lortat-Jacob, I. Mondor, G. Roca, R. Wyatt, J. Sodroski, L. Zhao, W. Olson, P. D. Kwong, and Q. J. Sattentau. 2000. Selective interactions of polyanions with basic surfaces on human immunodeficiency virus type 1 gp120. J. Virol. 74:1948-1960.
-
(2000)
J. Virol.
, vol.74
, pp. 1948-1960
-
-
Moulard, M.1
Lortat-Jacob, H.2
Mondor, I.3
Roca, G.4
Wyatt, R.5
Sodroski, J.6
Zhao, L.7
Olson, W.8
Kwong, P.D.9
Sattentau, Q.J.10
-
22
-
-
2942622122
-
Anti-HIV-1 activity of cellulose acetate phthalate: Synergy with soluble CD4 and induction of "dead-end" gp41 six-helix bundles
-
Neurath, A. R., N. Strick, S. Jiang, Y. Y. Li, and A. K. Debnath. 2002. Anti-HIV-1 activity of cellulose acetate phthalate: synergy with soluble CD4 and induction of "dead-end" gp41 six-helix bundles. BMC Infect. Dis. 2:6.
-
(2002)
BMC Infect. Dis.
, vol.2
, pp. 6
-
-
Neurath, A.R.1
Strick, N.2
Jiang, S.3
Li, Y.Y.4
Debnath, A.K.5
-
23
-
-
0036792716
-
Rectal applications of nonoxynol-9 cause tissue disruption in a monkey model
-
Patton, D. L., Y. T. Cosgrove Sweeney, L. K. Rabe, and S. L. Hillier. 2002. Rectal applications of nonoxynol-9 cause tissue disruption in a monkey model. Sex. Transm. Dis. 29:581-587.
-
(2002)
Sex. Transm. Dis.
, vol.29
, pp. 581-587
-
-
Patton, D.L.1
Cosgrove Sweeney, Y.T.2
Rabe, L.K.3
Hillier, S.L.4
-
24
-
-
0032552228
-
A controlled trial of nonoxynol 9 film to reduce male-to-female transmission of sexually transmitted diseases
-
Roddy, R. E., L. Zekeng, K. A. Ryan, U. Tamoufe, S. S. Weir, and E. L. Wong. 1998. A controlled trial of nonoxynol 9 film to reduce male-to-female transmission of sexually transmitted diseases. N. Engl. J. Med. 339:504-510.
-
(1998)
N. Engl. J. Med.
, vol.339
, pp. 504-510
-
-
Roddy, R.E.1
Zekeng, L.2
Ryan, K.A.3
Tamoufe, U.4
Weir, S.S.5
Wong, E.L.6
-
25
-
-
13344262687
-
Naphthalene sulfonate polymers with CD4-blocking and anti-human immunodeficiency virus type 1 activities
-
Rusconi, S., M. Moonis, D. P. Merrill, P. V. Pallai, E. A. Neidhardt, S. K. Sing, K. J. Willi, M. S. Osburne, A. T. Profy, J. C. Jenson, and M. S. Hirsch. 1996. Naphthalene sulfonate polymers with CD4-blocking and anti-human immunodeficiency virus type 1 activities. Antimicrob. Agents Chemother. 40:234-236.
-
(1996)
Antimicrob. Agents Chemother.
, vol.40
, pp. 234-236
-
-
Rusconi, S.1
Moonis, M.2
Merrill, D.P.3
Pallai, P.V.4
Neidhardt, E.A.5
Sing, S.K.6
Willi, K.J.7
Osburne, M.S.8
Profy, A.T.9
Jenson, J.C.10
Hirsch, M.S.11
-
26
-
-
0026100629
-
Identification and characterization of a novel non-infectious herpes simplex virus-related particle
-
Szilagyi, J. F., and C. Cunningham. 1991. Identification and characterization of a novel non-infectious herpes simplex virus-related particle. J. Gen. Virol. 72:661-668.
-
(1991)
J. Gen. Virol.
, vol.72
, pp. 661-668
-
-
Szilagyi, J.F.1
Cunningham, C.2
-
28
-
-
0037190597
-
Effectiveness of COL-1492, a nonoxynol-9 vaginal gel, on HIV-1 transmission in female sex workers: A randomised controlled trial
-
Van Damme, L., G. Ramjee, M. Alary, B. Vuylsteke, V. Chandeying, H. Rees, P. Sirivongrangson, L. Mukenge-Tshibaka, V. Ettiegne-Traore, C. Uaheowitchai, S. S. Karim, B. Masse, J. Perriens, and M. Laga. 2002. Effectiveness of COL-1492, a nonoxynol-9 vaginal gel, on HIV-1 transmission in female sex workers: a randomised controlled trial. Lancet 360:971-977.
-
(2002)
Lancet
, vol.360
, pp. 971-977
-
-
Van Damme, L.1
Ramjee, G.2
Alary, M.3
Vuylsteke, B.4
Chandeying, V.5
Rees, H.6
Sirivongrangson, P.7
Mukenge-Tshibaka, L.8
Ettiegne-Traore, V.9
Uaheowitchai, C.10
Karim, S.S.11
Masse, B.12
Perriens, J.13
Laga, M.14
-
29
-
-
0034059527
-
A phase I study of a novel potential intravaginal microbicide, PRO 2000, in healthy sexually inactive women
-
Van Damme, L., A. Wright, K. Depraetere, I. Rosenstein, V. Vandersmissen, L. Poulter, M. McKinlay, E. Van Dyck, J. Weber, A. Profy, M. Laga, and V. Kitchen. 2000. A phase I study of a novel potential intravaginal microbicide, PRO 2000, in healthy sexually inactive women. Sex. Transm. Infect. 76:126-130.
-
(2000)
Sex. Transm. Infect.
, vol.76
, pp. 126-130
-
-
Van Damme, L.1
Wright, A.2
Depraetere, K.3
Rosenstein, I.4
Vandersmissen, V.5
Poulter, L.6
McKinlay, M.7
Van Dyck, E.8
Weber, J.9
Profy, A.10
Laga, M.11
Kitchen, V.12
-
30
-
-
0036193979
-
Efficacy and safety of a new vaginal contraceptive antimicrobial formulation containing high molecular weight poly(sodium 4-styrenesulfonate)
-
Zaneveld, L. J., D. P. Waller, R. A. Anderson, C. Chany II, W. F. Rencher, K. Feathergill, X. H. Diao, G. F. Doncel, B. Herold, and M. Cooper. 2002. Efficacy and safety of a new vaginal contraceptive antimicrobial formulation containing high molecular weight poly(sodium 4-styrenesulfonate). Biol. Reprod. 66:886-894.
-
(2002)
Biol. Reprod.
, vol.66
, pp. 886-894
-
-
Zaneveld, L.J.1
Waller, D.P.2
Anderson, R.A.3
Chany II, C.4
Rencher, W.F.5
Feathergill, K.6
Diao, X.H.7
Doncel, G.F.8
Herold, B.9
Cooper, M.10
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