-
1
-
-
0027359827
-
WAF1, a potential mediator of p53 tumor suppression
-
el-Deiry WS, Tokino T, Velculescu VE, et al. WAF1, a potential mediator of p53 tumor suppression. Cell 1993; 75:817-25.
-
(1993)
Cell
, vol.75
, pp. 817-825
-
-
el-Deiry, W.S.1
Tokino, T.2
Velculescu, V.E.3
-
2
-
-
0027731971
-
Inhibition of CDK2 activity in vivo by an associated 20K regulatory subunit
-
Gu Y, Turck CW, Morgan DO. Inhibition of CDK2 activity in vivo by an associated 20K regulatory subunit. Nature 1993;366:707-10.
-
(1993)
Nature
, vol.366
, pp. 707-710
-
-
Gu, Y.1
Turck, C.W.2
Morgan, D.O.3
-
3
-
-
0027496935
-
-
Harper JW, Adami GR, Wei N, Keyomarsi K, EUedge Sj. The p21 Cdk~interaeting protein Cipl is a potent inhibitor of Gj cyclin-dependent kinases. Cell 1993;75: 805-16.
-
Harper JW, Adami GR, Wei N, Keyomarsi K, EUedge Sj. The p21 Cdk~interaeting protein Cipl is a potent inhibitor of Gj cyclin-dependent kinases. Cell 1993;75: 805-16.
-
-
-
-
4
-
-
0027717617
-
p21 is a universal inhibitor of cyclin kinases
-
Xiong Y, Harmon GJ, Zhang H, Casso D, Kobayashi R, Beach D. p21 is a universal inhibitor of cyclin kinases. Nature 1993;366:701-4.
-
(1993)
Nature
, vol.366
, pp. 701-704
-
-
Xiong, Y.1
Harmon, G.J.2
Zhang, H.3
Casso, D.4
Kobayashi, R.5
Beach, D.6
-
5
-
-
0037338643
-
p21WAFl expression in invasive breast cancer and its association with p53, AP-2, cell proliferation, and prognosis
-
Pellikainen MJ, Pekola XT, Ropponen KM, et al. p21WAFl expression in invasive breast cancer and its association with p53, AP-2, cell proliferation, and prognosis. J Clin Pathol 2003;56:214-20.
-
(2003)
J Clin Pathol
, vol.56
, pp. 214-220
-
-
Pellikainen, M.J.1
Pekola, X.T.2
Ropponen, K.M.3
-
6
-
-
14644427080
-
Correlations of cell cycle regulators (p53, p21, pRb and mdm2) and c-erbB-2 with biological markers of proliferation and overall survival in breast cancer
-
Pinto AE, Andre S, Laranjeira C, Soares j. Correlations of cell cycle regulators (p53, p21, pRb and mdm2) and c-erbB-2 with biological markers of proliferation and overall survival in breast cancer. Pathology (Phila) 2005; 37:45-50.
-
(2005)
Pathology (Phila)
, vol.37
, pp. 45-50
-
-
Pinto, A.E.1
Andre, S.2
Laranjeira, C.3
Soares, J.4
-
7
-
-
33947207819
-
HER-2, p53, p21 and hormonal receptors proteins expression as predictive factors of response and prognosis in locally advanced breast cancer treated with neoadjuvant docetaxel plus epiru- bicin combination
-
Tiezzi DG, Andrade JM, Ribeiro-Silva A, Zola EE, Marana HR, Tiezzi MG. HER-2, p53, p21 and hormonal receptors proteins expression as predictive factors of response and prognosis in locally advanced breast cancer treated with neoadjuvant docetaxel plus epiru- bicin combination. BMC Cancer 2007;7:36.
-
(2007)
BMC Cancer
, vol.7
, pp. 36
-
-
Tiezzi, D.G.1
Andrade, J.M.2
Ribeiro-Silva, A.3
Zola, E.E.4
Marana, H.R.5
Tiezzi, M.G.6
-
8
-
-
30144440248
-
The KEE4 tumour suppressor is a transcriptional repressor of p53 that acts as a context-dependent oncogene
-
Rowland BD, Bernards R, Peeper DS. The KEE4 tumour suppressor is a transcriptional repressor of p53 that acts as a context-dependent oncogene. Nat Cell Biol 2005;7:1074-82.
-
(2005)
Nat Cell Biol
, vol.7
, pp. 1074-1082
-
-
Rowland, B.D.1
Bernards, R.2
Peeper, D.S.3
-
9
-
-
38349137676
-
Tamoxifen- stimulated growth of breast cancer due to p2I loss
-
Abukhdeir AM, Vitolo Ml, Argani P, et al. Tamoxifen- stimulated growth of breast cancer due to p2I loss. Proc Natl Acad Sci U S A 2008;105:288-93.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 288-293
-
-
Abukhdeir, A.M.1
Vitolo, M.2
Argani, P.3
-
10
-
-
0027940495
-
Absence of WAF1 mutations in a variety of human malignancies
-
Shiohara M, el-Deiry WS, Wada M, et al. Absence of WAF1 mutations in a variety of human malignancies. Blood 1994;84:3781-4.
-
(1994)
Blood
, vol.84
, pp. 3781-3784
-
-
Shiohara, M.1
el-Deiry, W.S.2
Wada, M.3
-
11
-
-
0028220204
-
-
1 arrest. Cell 1994;76:1013-23.
-
1 arrest. Cell 1994;76:1013-23.
-
-
-
-
12
-
-
0028177401
-
1 arrest involves pRB-related proteins and is disrupted by the human papillomavirus 16 E7 oncoprotein
-
1 arrest involves pRB-related proteins and is disrupted by the human papillomavirus 16 E7 oncoprotein. Proc Natl Acad Sci U S A 1994;91:5320-4.
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, pp. 5320-5324
-
-
Slebos, R.1
Lee, M.H.2
Plunkett, R.S.3
-
13
-
-
0030759895
-
Arrest of the cell cycle by the tumour-suppressor BRCA1 requires the CDK-inhibitor p21WAFl/CiPl
-
Somasundaram K, Zhang H, Zeng YX, et aL Arrest of the cell cycle by the tumour-suppressor BRCA1 requires the CDK-inhibitor p21WAFl/CiPl. Nature 1997;389:187-90.
-
(1997)
Nature
, vol.389
, pp. 187-190
-
-
Somasundaram, K.1
Zhang, H.2
Zeng, Y.X.3
et aL.4
-
14
-
-
28844462784
-
p53-independent regulation of p21Wafl/Cipl expression and senescence by Chk2
-
Aliouat-Denis CM, Dendouga N, Van den Wyngaert I, et al. p53-independent regulation of p21Wafl/Cipl expression and senescence by Chk2. Mol Cancer Res 2005;3:627-34.
-
(2005)
Mol Cancer Res
, vol.3
, pp. 627-634
-
-
Aliouat-Denis, C.M.1
Dendouga, N.2
Van den Wyngaert, I.3
-
15
-
-
0035839554
-
Kruppel-like factor 4 (gut-enriched Kruppel-like factor) inhibits cell proliferation by blocking GrS progression of the cell cycle
-
Chen X, Johns DC, Geiman DE, et al. Kruppel-like factor 4 (gut-enriched Kruppel-like factor) inhibits cell proliferation by blocking GrS progression of the cell cycle, j Biol Chem 2001;276:30423-8.
-
(2001)
j Biol Chem
, vol.276
, pp. 30423-30428
-
-
Chen, X.1
Johns, D.C.2
Geiman, D.E.3
-
16
-
-
0034674712
-
The gut- enriched Kruppel-like factor (Kruppel-like factor 4} mediates the transactivating effect of p53 on the p21WAFl/Cipl promoter
-
Zhang W, Geiman DE, Shields JM, et al. The gut- enriched Kruppel-like factor (Kruppel-like factor 4} mediates the transactivating effect of p53 on the p21WAFl/Cipl promoter, j Biol Chem 2000;275:18391-8.
-
(2000)
j Biol Chem
, vol.275
, pp. 18391-18398
-
-
Zhang, W.1
Geiman, D.E.2
Shields, J.M.3
-
17
-
-
18244389734
-
KLF6, a candidate tumor suppressor gene mutated in prostate cancer
-
Narla G, Heath KE, Reeves HE, et al. KLF6, a candidate tumor suppressor gene mutated in prostate cancer. Science 2001;294:2563-6.
-
(2001)
Science
, vol.294
, pp. 2563-2566
-
-
Narla, G.1
Heath, K.E.2
Reeves, H.E.3
-
18
-
-
27944504221
-
-
I8. Duan Z, Zarebski A, Montoya-Durango D, Grimes HL, Horwitz M. Gfil coordinates epigenetic repression of p21Cip/WAFl by recruitment of histone lysine rnethyl- transferase G9a and histone deacetylase 1. Mol Cell Biol 2005;25:10338-51,
-
I8. Duan Z, Zarebski A, Montoya-Durango D, Grimes HL, Horwitz M. Gfil coordinates epigenetic repression of p21Cip/WAFl by recruitment of histone lysine rnethyl- transferase G9a and histone deacetylase 1. Mol Cell Biol 2005;25:10338-51,
-
-
-
-
19
-
-
0037383786
-
The tumor suppressor p53 and histone deacetylase 1 are antagonistic regulators of the cyclin-dependent kinase inhibitor p21/WAFl/CLPl gene.Mol
-
Lagger G, Doetzlhofer A, Schuettengruber B, et al. The tumor suppressor p53 and histone deacetylase 1 are antagonistic regulators of the cyclin-dependent kinase inhibitor p21/WAFl/CLPl gene.Mol Cell Biol 2003;23: 2669-79.
-
(2003)
Cell Biol
, vol.23
, pp. 2669-2679
-
-
Lagger, G.1
Doetzlhofer, A.2
Schuettengruber, B.3
-
20
-
-
0034730127
-
Histone deacetylase inhibitor selectively induces p21WAFl expression and gene-associated histone acet- ylation
-
Richon VM, Sandhoff TW, Rifkind RA, Marks PA. Histone deacetylase inhibitor selectively induces p21WAFl expression and gene-associated histone acet- ylation. Proc Natl Acad Sci U S A 2000;97:10014-9.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 10014-10019
-
-
Richon, V.M.1
Sandhoff, T.W.2
Rifkind, R.A.3
Marks, P.A.4
-
21
-
-
40949111565
-
BAF180 is a critical regulator of p21 induction and a tumor suppressor mutated in breast cancer
-
Xia W, Nagase S, MontiaAG, et al. BAF180 is a critical regulator of p21 induction and a tumor suppressor mutated in breast cancer. Cancer Res 2008;68:1667-74.
-
(2008)
Cancer Res
, vol.68
, pp. 1667-1674
-
-
Xia, W.1
Nagase, S.2
MontiaAG3
-
22
-
-
34250863911
-
FOXP3 is an X- linked breast cancer suppressor gene and an important repressor of the HER-2/ErbB2 oncogene
-
Zuo T, Wang L, Morrison C, et al. FOXP3 is an X- linked breast cancer suppressor gene and an important repressor of the HER-2/ErbB2 oncogene. Cell 2007;129: 1275-86.
-
(2007)
Cell
, vol.129
, pp. 1275-1286
-
-
Zuo, T.1
Wang, L.2
Morrison, C.3
-
23
-
-
36849053106
-
FOXP3 is a novel transcriptional repressor for the breast cancer oncogene SKP2
-
Zuo T, Liu R, Zhang H, et al. FOXP3 is a novel transcriptional repressor for the breast cancer oncogene SKP2. J Clin Invest 2007;117:3765-73.
-
(2007)
J Clin Invest
, vol.117
, pp. 3765-3773
-
-
Zuo, T.1
Liu, R.2
Zhang, H.3
-
24
-
-
26844476814
-
The Scurfy mutation of FoxP3 in the thymus stroma leads to defective thymopoiesis
-
Chang X, Gao JX, Jiang Q, et al. The Scurfy mutation of FoxP3 in the thymus stroma leads to defective thymopoiesis. J Exp Med 2005;202:1141-51.
-
(2005)
J Exp Med
, vol.202
, pp. 1141-1151
-
-
Chang, X.1
Gao, J.X.2
Jiang, Q.3
-
25
-
-
0027528769
-
A cell culture model system for genetic analyses of the cell cycle by targeted homologous recombination
-
Prouty SM, Hanson KD, Boyle AL, et al. A cell culture model system for genetic analyses of the cell cycle by targeted homologous recombination. Oncogene 1993;8: 899-907.
-
(1993)
Oncogene
, vol.8
, pp. 899-907
-
-
Prouty, S.M.1
Hanson, K.D.2
Boyle, A.L.3
-
26
-
-
0030849451
-
Phenotypes of c-Myc-deficient rat fibroblasts isolated by targeted homologous recombination
-
Mateyak MK, Obaya AJ, Adachi S, Sedivy JM. Phenotypes of c-Myc-deficient rat fibroblasts isolated by targeted homologous recombination. Cell Growth Differ 1997;8:1039-48.
-
(1997)
Cell Growth Differ
, vol.8
, pp. 1039-1048
-
-
Mateyak, M.K.1
Obaya, A.J.2
Adachi, S.3
Sedivy, J.M.4
-
27
-
-
29144535372
-
-
Dai M, Wang P, Boyd AD, et al. Evolving gene/ transcript definitions significantly alter the interpretation of GeneChip data. Nucleic Acids Res 2005;33:el 75.
-
Dai M, Wang P, Boyd AD, et al. Evolving gene/ transcript definitions significantly alter the interpretation of GeneChip data. Nucleic Acids Res 2005;33:el 75.
-
-
-
-
28
-
-
3843114956
-
-
Im H, Grass JA, Johnson KD, Boyer ME, Wu j, Bresnick EH. Measurement of protein-DNA interactions in vivo by chromatin immunoprecipitation. Methods Mol Biol 2004;284:129-46.
-
Im H, Grass JA, Johnson KD, Boyer ME, Wu j, Bresnick EH. Measurement of protein-DNA interactions in vivo by chromatin immunoprecipitation. Methods Mol Biol 2004;284:129-46.
-
-
-
-
29
-
-
4544352942
-
Transcriptional regulatory code of a eukaryotic genome
-
Harbison CT, Gordon DR, Lee Tl, et al. Transcriptional regulatory code of a eukaryotic genome. Nature 2004;431:99-104'
-
(2004)
Nature
, vol.431
, pp. 99-104
-
-
Harbison, C.T.1
Gordon, D.R.2
Lee, T.3
-
30
-
-
0034679603
-
The forkhead protein Fkh2 is a component of the yeast cell cycle transcription factor SFF
-
Pic A, Lim EL, Ross Sj, et al. The forkhead protein Fkh2 is a component of the yeast cell cycle transcription factor SFF. EMBO J 2000;19:3750-61.
-
(2000)
EMBO J
, vol.19
, pp. 3750-3761
-
-
Pic, A.1
Lim, E.L.2
Ross, S.3
-
31
-
-
0028598642
-
Complex organization of CTF/NF-I, C/EBP, and HNF3 binding sites within the promoter of the liver-specific vitellogenin gene
-
Cardinaux JR, Chapel S, Wahli W. Complex organization of CTF/NF-I, C/EBP, and HNF3 binding sites within the promoter of the liver-specific vitellogenin gene. J Biol Chem 1994;269:32947-56.
-
(1994)
J Biol Chem
, vol.269
, pp. 32947-32956
-
-
Cardinaux, J.R.1
Chapel, S.2
Wahli, W.3
-
32
-
-
17344379513
-
Five years on the wings of fork head
-
Kaufmann E, Knochel W. Five years on the wings of fork head. Mech Dev 1996;57:3-20.
-
(1996)
Mech Dev
, vol.57
, pp. 3-20
-
-
Kaufmann, E.1
Knochel, W.2
-
33
-
-
0037126303
-
Myc suppression of the p21(Cipl) Cdk inhibitor influences the outcome of the p53 response to DNA damage
-
Seoane J, Le HV, Massague J. Myc suppression of the p21(Cipl) Cdk inhibitor influences the outcome of the p53 response to DNA damage. Nature 2002;419: 729-34.
-
(2002)
Nature
, vol.419
, pp. 729-734
-
-
Seoane, J.1
Le, H.V.2
Massague, J.3
-
34
-
-
0032920581
-
Overexpression of c-Myc inhibits p21WAFl/CFPl expression and induces S-phase entry in 12-0-tetradecanoylphorbol-13-acetate (TPA)- sensitive human cancer cells
-
Mitchell KO, El-Deiry WS. Overexpression of c-Myc inhibits p21WAFl/CFPl expression and induces S-phase entry in 12-0-tetradecanoylphorbol-13-acetate (TPA)- sensitive human cancer cells. Cell Growth Differ 1999;10: 223-30.
-
(1999)
Cell Growth Differ
, vol.10
, pp. 223-230
-
-
Mitchell, K.O.1
El-Deiry, W.S.2
-
35
-
-
0034662959
-
A role for transcriptional repression of p21CFPl by c-Myc in overcoming transforming growth factor β induced cell-cycle arrest
-
Claassen GF, Hann SR. A role for transcriptional repression of p21CFPl by c-Myc in overcoming transforming growth factor β induced cell-cycle arrest. Proc Natl Acad Sci U S A 2000;97:9498-503. '
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 9498-9503
-
-
Claassen, G.F.1
Hann, S.R.2
-
36
-
-
33846016948
-
Transcriptional regulation by Foxp3 is associated with direct promoter occupancy and modulation of histone acetylation
-
Chen C, Rowell FA, Thomas RM, Hancock WW, Wells AD. Transcriptional regulation by Foxp3 is associated with direct promoter occupancy and modulation of histone acetylation. J Biol Chem 2006; 281:36828-34.
-
(2006)
J Biol Chem
, vol.281
, pp. 36828-36834
-
-
Chen, C.1
Rowell, F.A.2
Thomas, R.M.3
Hancock, W.W.4
Wells, A.D.5
-
37
-
-
0033963601
-
Involvement of p21(Wafl/Cipl) and its cleavage by DEVD-caspase during apoptosis of colorectal cancer cells induced by butyrate
-
Chai F, Evdokiou A Young GP, Zalewski PD. Involvement of p21(Wafl/Cipl) and its cleavage by DEVD-caspase during apoptosis of colorectal cancer cells induced by butyrate. Carcinogenesis 2000; 21:7-14.
-
(2000)
Carcinogenesis
, vol.21
, pp. 7-14
-
-
Chai, F.1
Evdokiou, A.2
Young, G.P.3
Zalewski, P.D.4
-
38
-
-
52949138267
-
TGF-p and IL-6 signals modulate chromatin binding and promoter occupancy by acetylated FOXP3
-
Samanta A, Li R, Song X, et al. TGF-p and IL-6 signals modulate chromatin binding and promoter occupancy by acetylated FOXP3. Proc Natl Acad Sci U S A 2008; 105: 14023-7.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 14023-14027
-
-
Samanta, A.1
Li, R.2
Song, X.3
|