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Volumn 4, Issue 4, 2009, Pages 524-528

Design, synthesis, and biological evaluation of levoglucosenone-derived ras activation inhibitors

(12) MüIIer, Christian b Frau, Maria Antonia Gomez Zurita b Ballinari, Dario b Colombo, Sonia a Bitto, Alessandro a Martegani, Enzo a Airoldi, Cristina a Van Neuren, Anske Stephanie c Stein, Matthias c Weiser, Jorg c Battistini, Carlo b Peri, Francesco a

a UNIVERSITY OF MILANO BICOCCA (Italy)

b B U Oncology (Italy)

c Anterio Consult and Research GmbH (Germany)

Author keywords

Antitumor agents; Cycloaddition; Molecular modeling; NMR; Signal transduction

Indexed keywords

ANTINEOPLASTIC AGENT; BENZYL DERIVATIVE; ENZYME INHIBITOR; LEVOGLUCOSENONE; LEWIS ACID; NATURAL PRODUCT; RAS PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST ADENOCARCINOMA; CANCER CELL; CANCER CELL CULTURE; CANCER INHIBITION; CELL STRAIN HCT116; CELL STRAIN MCF 7; CHROMATID EXCHANGE; COLON CANCER; COMBINATORIAL CHEMISTRY; CYCLOADDITION; DIASTEREOISOMER; DRUG DESIGN; DRUG SYNTHESIS; ENZYME ACTIVATION; FEMALE; GENE ACTIVATION; HUMAN; HUMAN CELL; IN VITRO STUDY; LUNG CARCINOMA; NONHUMAN; ONCOGENE RAS; OVARY CANCER; PHARMACOPHORE; PRIORITY JOURNAL; STEREOCHEMISTRY;

ANIMALS; BICYCLO COMPOUNDS, HETEROCYCLIC; CELL LINE; CELL PROLIFERATION; DRUG DESIGN; ENZYME INHIBITORS; GLUCOSE; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR STRUCTURE; RAS PROTEINS;

EID: 65549131646 PISSN: 18607179 EISSN: 18607187 Source Type: Journal
DOI: 10.1002/cmdc.200800416 Document Type: Article

Times cited : (32)

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