Cyclic hydraulic pressure and fluid flow differentially modulate cytoskeleton re-organization in MC3T3 osteoblasts

Cellular and Molecular Bioengineering

Volumn 2, Issue 1, 2009, Pages 133-143

  Gardinier, Joseph D ^a   Majumdar, Shyama ^a   Duncan, Randall L ^a   Wang, Liyun ^a  

^a UNIVERSITY OF DELAWARE   (United States)

Author keywords

AFM; ATP release; Cell stiffness; COX 2; F actin; Mechanotransduction; Microtubule

Indexed keywords

CYCLOOXYGENASE 2; F ACTIN;

ANIMAL CELL; ARTICLE; ATOMIC FORCE MICROSCOPY; BIOSYNTHESIS; CELL ACTIVITY; CELL DIFFERENTIATION; CELL LINE; CELL STRAIN MC3T3; CYCLIC HYDRAULIC PRESSURE; CYTOSKELETON; FLUID FLOW; MICROTUBULE; MOUSE; NONHUMAN; OSTEOBLAST; POLYMERIZATION; PRIORITY JOURNAL; SHEAR STRESS; STIMULUS RESPONSE;

CHANDIPURA VIRUS;

EID: 65549126737     PISSN: 18655025     EISSN: 18655033     Source Type: Journal    
DOI: 10.1007/s12195-008-0038-2     Document Type: Article

References (55)

1. E. H. Burger J. Klein-Nulen 1999 Responses of bone cells to biomechanical forces in vitro Adv. Dent. Res. 13 93 98
2. J. M. Caffrey M. C. Farach-Carson 1989 Vitamin D3 metabolites modulate dihydropyridine-sensitive calcium currents in clonal rat osteosarcoma cells J. Biol. Chem. 264 34 20265 20274 (Pubitemid 20009206)
3. G. T. Charras M. A. Horton 2002 Single cell mechanotransduction and its modulation analyzed by atomic force microscope indentation Biophys. J. 82 6 2970 2981 (Pubitemid 34547640)
4. N. X. Chen D. J. Geist D. C. Genetos F. M. Pavalko R. L. Duncan 2003 Fluid shear-induced NFkappaB translocation in osteoblasts is mediated by intracellular calcium release Bone 33 3 399 410 (Pubitemid 37103256)
5. N. X. Chen K. D. Ryder F. M. Pavalko C. H. Turner D. B. Burr J. Qiu R. L. Duncan 2000 Ca(2+) regulates fluid shear-induced cytoskeletal reorganization and gene expression in osteoblasts Am. J. Physiol. Cell Physiol. 278 5 C989 C997 (Pubitemid 30346935)
6. D. Docheva D. Padula C. Popov W. Mutschler H. Clausen-Schaumann M. Schieker 2008 Researching into the cellular shape, volume and elasticity of mesenchymal stem cells, osteoblasts and osteosarcoma cells by atomic force microscopy J. Cell Mol. Med. 12 2 537 552
7. R. Duncan S. Misler 1989 Voltage-activated and stretch-activated Ba2+ conducting channels in an osteoblast-like cell line (UMR 106) FEBS Lett. 251 1-2 17 21 (Pubitemid 19181844)
8. R. L. Duncan C. H. Turner 1995 Mechanotransduction and the functional response of bone to mechanical strain Calcif. Tissue Int. 57 5 344 358
9. M. R. Forwood 1996 Inducible cyclo-oxygenase (COX-2) mediates the induction of bone formation by mechanical loading in vivo J. Bone Miner. Res. 11 11 1688 1693 (Pubitemid 26367679)
10. D. C. Genetos D. J. Geist D. Liu H. J. Donahue R. L. Duncan 2005 Fluid shear-induced ATP secretion mediates prostaglandin release in MC3T3-E1 osteoblasts J. Bone Miner. Res. 20 1 41 49 (Pubitemid 41716217)
11. H. Glanstchnig F. Varga M. Rumpler K. Klaushofer 1996 Prostacyclin (PGI2): a potential mediator of c-fos expression induced by hydrostatic pressure in osteoblastic cells Eur. J. Clin. Invest. 26 7 544 548 (Pubitemid 26291903)
12. B. P. Helmke P. F. Davies 2002 The cytoskeleton under external fluid mechanical forces: hemodynamic forces acting on the endothelium Ann. Biomed. Eng. 30 3 284 296 (Pubitemid 34690553)
13. 2+ response of bone cells experiencing fluid flow J. Biomech. 29 11 1411 1417 (Pubitemid 26329190)
14. C. R. Jacobs C. E. Yellowley B. R. Davis Z. Zhou J. M. Cimbala H. J. Donahue 1998 Differential effect of steady versus oscillating flow on bone cells J. Biomech. 31 11 969 976 (Pubitemid 28561790)
15. S. Katz R. Boland G. Santillan 2006 Modulation of ERK 1/2 and p38 MAPK signaling pathways by ATP in osteoblasts: involvement of mechanical stress-activated calcium influx, PKC and Src activation Int. J. Biochem. Cell Biol. 38 12 2082 2091 (Pubitemid 44397616)
16. P. J. Kelly J. T. Bronk 1990 Venous pressure and bone formation Microvasc. Res. 39 3 364 375 (Pubitemid 20188942)
17. J. Klein-Nulend J. Roelofsen C. M. Semeins A. L. Bronckers E. H. Burger 1997 Mechanical stimulation of osteopontin mRNA expression and synthesis in bone cell cultures J. Cell Physiol. 170 2 174 181 (Pubitemid 27076218)
18. J. Klein-Nulend J. Roelofsen J. G. Sterck C. M. Semeins E. H. Burger 1995 Mechanical loading stimulates the release of transforming growth factor-beta activity by cultured mouse calvariae and periosteal cells J. Cell Physiol. 163 1 115 119
19. M. M. Knight T. Toyoda D. A. Lee D. L. Bader 2006 Mechanical compression and hydrostatic pressure induce reversible changes in actin cytoskeletal organisation in chondrocytes in agarose J. Biomech. 39 8 1547 1551
20. J. Li D. Liu H. Z. Ke R. L. Duncan C. H. Turner 2005 The P2X7 nucleotide receptor mediates skeletal mechanotransduction J. Biol. Chem. 280 52 42952 42959 (Pubitemid 43049258)
21. A. F. Mak W. M. Lai V. C. Mow 1987 Biphasic indentation of articular cartilage-I. Theoretical analysis J. Biomech. 20 7 703 714 (Pubitemid 17654722)
22. M. C. Meazzini C. D. Toma J. L. Schaffer M. L. Gray L. C. Gerstenfeld 1998 Osteoblast cytoskeletal modulation in response to mechanical strain in vitro J. Orthop. Res. 16 2 170 180 (Pubitemid 28249155)
23. R. E. Mott B. P. Helmke 2007 Mapping the dynamics of shear stress-induced structural changes in endothelial cells Am. J. Physiol. Cell Physiol. 293 5 C1616 C1626
24. K. A. Myers J. B. Rattner N. G. Shrive D. A. Hart 2007 Hydrostatic pressure sensation in cells: integration into the tensegrity model Biochem. Cell Biol. 85 5 543 551 (Pubitemid 350073440)
25. K. A. Myers J. B. Rattner N. G. Shrive D. A. Hart 2007 Osteoblast-like cells and fluid flow: cytoskeleton-dependent shear sensitivity Biochem. Biophys. Res. Commun. 364 2 214 219 (Pubitemid 350001347)
26. S. Na O. Collin F. Chowdhury B. Tay M. Ouyang Y. Wang N. Wang 2008 Rapid signal transduction in living cells is a unique feature of mechanotransduction Proc. Natl. Acad. Sci. USA 105 18 6626 6631
27. J. Nagatomi B. P. Arulanandam D. W. Metzger A. Meunier R. Bizios 2001 Frequency- and duration-dependent effects of cyclic pressure on select bone cell functions Tissue Eng. 7 6 717 728 (Pubitemid 34042304)
28. J. Nagatomi B. P. Arulanandam D. W. Metzger A. Meunier R. Bizios 2003 Cyclic pressure affects osteoblast functions pertinent to osteogenesis Ann. Biomed. Eng. 31 8 917 923
29. S. M. Norvell S. M. Ponik D. K. Bowen R. Gerard F. M. Pavalko 2004 Fluid shear stress induction of COX-2 protein and prostaglandin release in cultured MC3T3-E1 osteoblasts does not require intact microfilaments or microtubules J. Appl. Physiol. 96 3 957 966 (Pubitemid 38248669)
30. I. Owan D. B. Burr C. H. Turner J. Qiu Y. Tu J. E. Onyia R. L. Duncan 1997 Mechanotransduction in bone: osteoblasts are more responsive to fluid forces than mechanical strain Am. J. Physiol. 273 3 Pt 1 C810 C815 (Pubitemid 27422158)
31. F. M. Pavalko N. X. Chen C. H. Turner D. B. Burr S. Atkinson Y. F. Hsieh J. Qiu R. L. Duncan 1998 Fluid shear-induced mechanical signaling in MC3T3-E1 osteoblasts requires cytoskeleton-integrin interactions Am. J. Physiol. 275 6 Pt 1 C1591 601 (Pubitemid 128734291)
32. A. E. Pelling M. A. Horton 2008 An historical perspective on cell mechanics Pflugers Arch. 456 1 3 12
33. Y. X. Qin T. Kaplan A. Saldanha C. Rubin 2003 Fluid pressure gradients, arising from oscillations in intramedullary pressure, is correlated with the formation of bone and inhibition of intracortical porosity J. Biomech. 36 10 1427 1437 (Pubitemid 37117350)
34. Y. X. Qin W. Lin C. Rubin 2002 The pathway of bone fluid flow as defined by in vivo intramedullary pressure and streaming potential measurements Ann. Biomed. Eng. 30 5 693 702
35. M. Radmacher M. Fritz C. M. Kacher J. P. Cleveland P. K. Hansma 1996 Measuring the viscoelastic properties of human platelets with the atomic force microscope Biophys. J. 70 1 556 567 (Pubitemid 26021495)
36. K. M. Reich C. V. Gay J. A. Frangos 1990 Fluid shear stress as a mediator of osteoblast cyclic adenosine monophosphate production J. Cell Physiol. 143 1 100 104 (Pubitemid 20123795)
37. J. Roelofsen J. Klein-Nulend E. H. Burger 1995 Mechanical stimulation by intermittent hydrostatic compression promotes bone-specific gene expression in vitro J. Biomech. 28 12 1493 1503 (Pubitemid 26004295)
38. C. T. Rubin L. E. Lanyon 1984 Regulation of bone formation by applied dynamic loads J Bone Joint Surg. Am. 66 3 397 402 (Pubitemid 14169460)
39. J. Rubin C. Rubin C. R. Jacobs 2006 Molecular pathways mediating mechanical signaling in bone Gene 367 1 16 (Pubitemid 43286736)
40. S. Saito P. Ngan T. Rosol M. Saito H. Shimizu N. Shinjo J. Shanfeld Z. Davidovitch 1991 Involvement of PGE synthesis in the effect of intermittent pressure and interleukin-1 beta on bone resorption J. Dent. Res. 70 1 27 33
41. M. Schliwa U. Euteneuer J. C. Bulinski J. G. Izant 1981 Calcium lability of cytoplasmic microtubules and its modulation by microtubule-associated proteins Proc. Natl. Acad. Sci. USA 78 2 1037 1041 (Pubitemid 11100765)
42. N. D. Searby C. R. Steele R. K. Globus 2005 Influence of increased mechanical loading by hypergravity on the microtubule cytoskeleton and prostaglandin E2 release in primary osteoblasts Am. J. Physiol. Cell Physiol. 289 1 C148 C158 (Pubitemid 40880835)
43. Y. R. Silberberg A. E. Pelling G. E. Yakubov W. R. Crum D. J. Hawkes M. A. Horton 2008 Mitochondrial displacements in response to nanomechanical forces J. Mol. Recognit. 21 1 30 36
44. H. Y. Stevens D. R. Meays J. A. Frangos 2006 Pressure gradients and transport in the murine femur upon hindlimb suspension Bone 39 3 565 572 (Pubitemid 44149282)
45. H. Y. Stevens D. R. Meays J. Yeh L. M. Bjursten J. A. Frangos 2006 COX-2 is necessary for venous ligation-mediated bone adaptation in mice Bone 38 1 93 104 (Pubitemid 43006079)
46. M. Stolz R. Raiteri A. U. Daniels M. R. VanLandingham W. Baschong U. Aebi 2004 Dynamic elastic modulus of porcine articular cartilage determined at two different levels of tissue organization by indentation-type atomic force microscopy Biophys. J. 86 5 3269 3283 (Pubitemid 38552726)
47. E. Takai K. D. Costa A. Shaheen C. T. Hung X. E. Guo 2005 Osteoblast elastic modulus measured by atomic force microscopy is substrate dependent Ann. Biomed. Eng. 33 7 963 971
48. E. Takai R. L. Mauck C. T. Hung X. E. Guo 2004 Osteocyte viability and regulation of osteoblast function in a 3D trabecular bone explant under dynamic hydrostatic pressure J. Bone Miner. Res. 19 9 1403 1410 (Pubitemid 41094341)
49. Uhthoff, H. K. and Z. F. Jaworski. Bone loss in response to long-term immobilisation. J. Bone Joint Surg. Br. 60-B(3):420-429, 1978
50. K. Weber P. C. Rathke M. Osborn 1978 Cytoplasmic microtubular images in glutaraldehyde-fixed tissue culture cells by electron microscopy and by immunofluorescence microscopy Proc. Natl. Acad. Sci. USA 75 4 1820 1824 (Pubitemid 8337561)
51. S. Weinbaum S. C. Cowin Y. Zeng 1994 A model for the excitation of osteocytes by mechanical loading-induced bone fluid shear stresses J. Biomech. 27 3 339 360 (Pubitemid 24061729)
52. J. You C. R. Jacobs T. H. Steinberg H. J. Donahue 2002 P2Y purinoceptors are responsible for oscillatory fluid flow-induced intracellular calcium mobilization in osteoblastic cells J. Biol. Chem. 277 50 48724 48729 (Pubitemid 35470837)
53. J. You C. E. Yellowley H. J. Donahue Y. Zhang Q. Chen C. R. Jacobs 2000 Substrate deformation levels associated with routine physical activity are less stimulatory to bone cells relative to loading-induced oscillatory fluid flow J. Biomech. Eng. 122 4 387 393
54. 2+ signaling in osteoblasts J. Bone Miner. Res. 21 11 1729 1737 (Pubitemid 46141228)
55. D. Zhang S. Weinbaum S. C. Cowin 1998 Estimates of the peak pressures in bone pore water J. Biomech. Eng. 120 6 697 703 (Pubitemid 29004082)