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Volumn 10, Issue 2, 2009, Pages 148-153

Potential novel targets in breast cancer

Author keywords

Bone marrow; Breast cancer; Cancer stem cells; Gap junction; Mesenchymal stem cells

Indexed keywords

CONNEXIN 26; CONNEXIN 43; GAP JUNCTION PROTEIN; HYPOXIA INDUCIBLE FACTOR; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MICRORNA;

EID: 65549123742     PISSN: 13892010     EISSN: 18734316     Source Type: Journal    
DOI: 10.2174/138920109787315024     Document Type: Review
Times cited : (4)

References (73)
  • 1
    • 50549121134 scopus 로고
    • The distribution of secondary growths in cancer of the breast
    • Paget, S. (1889) The distribution of secondary growths in cancer of the breast. The Lancet, 133(3421), 571-573.
    • (1889) The Lancet , vol.133 , Issue.3421 , pp. 571-573
    • Paget, S.1
  • 2
    • 33846044750 scopus 로고    scopus 로고
    • Bone marrow cells in the pre-metastatic niche within bone and beyond
    • Kaplan, R.; Psaila, B. and Lyden, D. (2006) Bone marrow cells in the pre-metastatic niche within bone and beyond. Cancer Metastasis Rev., 25(4), 521-529.
    • (2006) Cancer Metastasis Rev , vol.25 , Issue.4 , pp. 521-529
    • Kaplan, R.1    Psaila, B.2    Lyden, D.3
  • 3
    • 4344718326 scopus 로고    scopus 로고
    • Facilitating role of preprotachykinin-I gene in the integration of breast cancer cells within the stromal compartment of the bone marrow, A model of early cancer progression
    • Rao, G.; Patel, P.S.; Idler, S.P.; Maloof, P.; Gascon, P.; Potian, J.A. and Rameshwar, P. (2004) Facilitating role of preprotachykinin-I gene in the integration of breast cancer cells within the stromal compartment of the bone marrow, A model of early cancer progression. Cancer Res., 64(8), 2874-2881.
    • (2004) Cancer Res , vol.64 , Issue.8 , pp. 2874-2881
    • Rao, G.1    Patel, P.S.2    Idler, S.P.3    Maloof, P.4    Gascon, P.5    Potian, J.A.6    Rameshwar, P.7
  • 4
    • 33751189144 scopus 로고    scopus 로고
    • SDF-1alpha regulation in breast cancer cells contacting bone marrow stroma is critical for normal hematopoiesis
    • Moharita, A.L.; Taborga, M.; Corcoran, K.E.; Bryan, M.; Patel, P.S. and Rameshwar, P. (2006) SDF-1alpha regulation in breast cancer cells contacting bone marrow stroma is critical for normal hematopoiesis. Blood, 108(10), 3245-3252.
    • (2006) Blood , vol.108 , Issue.10 , pp. 3245-3252
    • Moharita, A.L.1    Taborga, M.2    Corcoran, K.E.3    Bryan, M.4    Patel, P.S.5    Rameshwar, P.6
  • 5
    • 4344647262 scopus 로고    scopus 로고
    • Bone marrow stroma influences transforming growth factor-beta production in breast cancer cells to regulate c-myc activation of the preprotachykinin I gene in breast cancer cells
    • Oh, H.S.; Moharita, A.; Potian, J.G.; Whitehead, I.P.; Livingston, J.C.; Castro, T.A.; Patel, P.S. and Rameshwar, P. (2004) Bone marrow stroma influences transforming growth factor-beta production in breast cancer cells to regulate c-myc activation of the preprotachykinin I gene in breast cancer cells. Cancer Res., 64(17), 6327-6336.
    • (2004) Cancer Res , vol.64 , Issue.17 , pp. 6327-6336
    • Oh, H.S.1    Moharita, A.2    Potian, J.G.3    Whitehead, I.P.4    Livingston, J.C.5    Castro, T.A.6    Patel, P.S.7    Rameshwar, P.8
  • 6
    • 28444459876 scopus 로고    scopus 로고
    • Transformation of breast cells by truncated neurokinin-1 receptor is secondary to activation by preprotachykinin-A peptides
    • Patel, H.J.; Ramkissoon, S.H.; Patel, P.S. and Rameshwar, P. (2005) Transformation of breast cells by truncated neurokinin-1 receptor is secondary to activation by preprotachykinin-A peptides. Proc. Natl. Acad. Sci. USA, 102(48), 17436-17441.
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , Issue.48 , pp. 17436-17441
    • Patel, H.J.1    Ramkissoon, S.H.2    Patel, P.S.3    Rameshwar, P.4
  • 7
    • 33750306612 scopus 로고    scopus 로고
    • Most early disseminated cancer cells detected in bone marrow of breast cancer patients have a putative breast cancer stem cell phenotype
    • Balic, M.; Lin, H.; Young, L.; Hawes, D.; Giuliano, A.; McNamara, G.; Datar, R.H. and Cote, R.J. (2006) Most early disseminated cancer cells detected in bone marrow of breast cancer patients have a putative breast cancer stem cell phenotype. Clin. Cancer Res., 12(19), 5615-5621.
    • (2006) Clin. Cancer Res , vol.12 , Issue.19 , pp. 5615-5621
    • Balic, M.1    Lin, H.2    Young, L.3    Hawes, D.4    Giuliano, A.5    McNamara, G.6    Datar, R.H.7    Cote, R.J.8
  • 8
    • 0344444733 scopus 로고    scopus 로고
    • Bone marrow micrometastases as a prognostic factor in early breast cancer patients
    • Alexandrova, E.; Sergieva, S.; Nikolova, V. and Danon, S. (2003) Bone marrow micrometastases as a prognostic factor in early breast cancer patients. J. BUON, 8(2), 133-137.
    • (2003) J. BUON , vol.8 , Issue.2 , pp. 133-137
    • Alexandrova, E.1    Sergieva, S.2    Nikolova, V.3    Danon, S.4
  • 10
    • 0033986270 scopus 로고    scopus 로고
    • Lack of effect of adjuvant chemotherapy on the elimination of single dormant tumor cells in bone marrow of high-risk breast cancer patients
    • Braun, S.; Kentenich, C.; Janni, W.; Hepp, F.; de Willgeroth, F.; Sommer, H. and Pantel, K. (2000) Lack of effect of adjuvant chemotherapy on the elimination of single dormant tumor cells in bone marrow of high-risk breast cancer patients. J. Clin. Oncol., 18(1), 80-86.
    • (2000) J. Clin. Oncol , vol.18 , Issue.1 , pp. 80-86
    • Braun, S.1    Kentenich, C.2    Janni, W.3    Hepp, F.4    de Willgeroth, F.5    Sommer, H.6    Pantel, K.7
  • 11
    • 0033996457 scopus 로고    scopus 로고
    • Braun, S., Pantel, K., Muller, P., Janni, W., Hepp, F., Kentenich, C.R.M. Gastroph, S., Wischnik, A., Dimpfl, T., Kindermann, G., Riethmuller, G. and Schlimok, G. (2000) Cytokeratin-positive cells in the bone marrow and survival of patients with Stage I, II, or III breast cancer. N. Engl. J. Med., 342(8), 525-533.
    • Braun, S., Pantel, K., Muller, P., Janni, W., Hepp, F., Kentenich, C.R.M. Gastroph, S., Wischnik, A., Dimpfl, T., Kindermann, G., Riethmuller, G. and Schlimok, G. (2000) Cytokeratin-positive cells in the bone marrow and survival of patients with Stage I, II, or III breast cancer. N. Engl. J. Med., 342(8), 525-533.
  • 12
    • 43049180078 scopus 로고    scopus 로고
    • Immunological properties of mesenchymal stem cells and clinical implications
    • Patel, S.A., Sherman, L., Munoz, J. and Rameshwar, P. (2008) Immunological properties of mesenchymal stem cells and clinical implications. Arch. Immunol. Ther. Exp., 56(1), 1-8.
    • (2008) Arch. Immunol. Ther. Exp , vol.56 , Issue.1 , pp. 1-8
    • Patel, S.A.1    Sherman, L.2    Munoz, J.3    Rameshwar, P.4
  • 13
    • 0030768933 scopus 로고    scopus 로고
    • Reverse transcriptase polymerase chain reaction analysis of parathyroid hormone-related protein for the detection of tumor cell dissemination in the peripheral blood and bone marrow of patients with breast cancer
    • Wulf, G.G.; Jorgens, B.; Liersch, T.; Gatzemeier, W.; Rauschecker, H.; Buske, C.; Hofner, M.; Hiddemann, W. and Wormann, B. (1997) Reverse transcriptase polymerase chain reaction analysis of parathyroid hormone-related protein for the detection of tumor cell dissemination in the peripheral blood and bone marrow of patients with breast cancer. J. Cancer Res. Clin. Oncol., 123(9), 514-521.
    • (1997) J. Cancer Res. Clin. Oncol , vol.123 , Issue.9 , pp. 514-521
    • Wulf, G.G.1    Jorgens, B.2    Liersch, T.3    Gatzemeier, W.4    Rauschecker, H.5    Buske, C.6    Hofner, M.7    Hiddemann, W.8    Wormann, B.9
  • 15
    • 0035856010 scopus 로고    scopus 로고
    • Chemokines and the Molecular Basis of Cancer Metastasis
    • Murphy, P.M. (2001) Chemokines and the Molecular Basis of Cancer Metastasis. N. Engl. J. Med., 345(11), 833-835.
    • (2001) N. Engl. J. Med , vol.345 , Issue.11 , pp. 833-835
    • Murphy, P.M.1
  • 17
    • 33847227974 scopus 로고    scopus 로고
    • The stem cell niche in health and leukemic disease
    • Scadden, D.T. (2007) The stem cell niche in health and leukemic disease. Best Pract. Res. Clin. Haematol., 20(1), 19-27.
    • (2007) Best Pract. Res. Clin. Haematol , vol.20 , Issue.1 , pp. 19-27
    • Scadden, D.T.1
  • 18
    • 24344506258 scopus 로고    scopus 로고
    • Cancer stem cells, lessons from leukemia
    • Wang, J.C.Y.; Dick, J.E. (2005) Cancer stem cells, lessons from leukemia. Trends Cell Biol., 15(9), 494-501.
    • (2005) Trends Cell Biol , vol.15 , Issue.9 , pp. 494-501
    • Wang, J.C.Y.1    Dick, J.E.2
  • 19
    • 0035499267 scopus 로고    scopus 로고
    • Stem cells, cancer, and cancer stem cells
    • Reya, T.; Morrison, S.J.; Clarke, M.F. and Weissman, I.L. (2001) Stem cells, cancer, and cancer stem cells. Nature, 414(6859), 105-111.
    • (2001) Nature , vol.414 , Issue.6859 , pp. 105-111
    • Reya, T.1    Morrison, S.J.2    Clarke, M.F.3    Weissman, I.L.4
  • 21
    • 0002740313 scopus 로고
    • A quantitative assay for the number of murine lymphoma cells capable of proliferation in vivo
    • Bruce, W.R. and Gaagh, V.D. (1963) A quantitative assay for the number of murine lymphoma cells capable of proliferation in vivo. Nature, 199, 79-80.
    • (1963) Nature , vol.199 , pp. 79-80
    • Bruce, W.R.1    Gaagh, V.D.2
  • 22
    • 34247527730 scopus 로고    scopus 로고
    • Hypoxia-inducible factors, stem cells, and cancer
    • Keith, B. and Simon, M.C. (2007) Hypoxia-inducible factors, stem cells, and cancer. Cell, 129(3), 465-472.
    • (2007) Cell , vol.129 , Issue.3 , pp. 465-472
    • Keith, B.1    Simon, M.C.2
  • 23
    • 34248359065 scopus 로고    scopus 로고
    • Distribution of hematopoietic stem cells in the bone marrow according to regional hypoxia
    • Parmar, K.; Mauch, P.; Vergilio, J.A.; Sackstein, R. and Down, J.D. (2007) Distribution of hematopoietic stem cells in the bone marrow according to regional hypoxia. Proc. Natl Acad. Sci. USA, 104(13), 5431-5436.
    • (2007) Proc. Natl Acad. Sci. USA , vol.104 , Issue.13 , pp. 5431-5436
    • Parmar, K.1    Mauch, P.2    Vergilio, J.A.3    Sackstein, R.4    Down, J.D.5
  • 24
    • 33646435309 scopus 로고    scopus 로고
    • The stem cell niches in bone
    • Yin, T. and Li, L. (2006) The stem cell niches in bone. J. Clin. Invest. 116(5), 1195-1201.
    • (2006) J. Clin. Invest , vol.116 , Issue.5 , pp. 1195-1201
    • Yin, T.1    Li, L.2
  • 25
    • 0034907875 scopus 로고    scopus 로고
    • Modeling pO2 distributions in the bone marrow hematopoietic compartment. II. Modified Kroghian Models
    • Chow, D.C.; Wenning, L.A.; Miller, W.M. and Papoutsakis, E.T. (2001) Modeling pO2 distributions in the bone marrow hematopoietic compartment. II. Modified Kroghian Models. Biophys. J., 81(2), 685-696.
    • (2001) Biophys. J , vol.81 , Issue.2 , pp. 685-696
    • Chow, D.C.1    Wenning, L.A.2    Miller, W.M.3    Papoutsakis, E.T.4
  • 26
    • 34248339947 scopus 로고    scopus 로고
    • Cancer stem cells, A review
    • Spillane, J.B. and Henderson, M.A. (2007) Cancer stem cells, A review. J. Surg., 77(6), 464-468.
    • (2007) J. Surg , vol.77 , Issue.6 , pp. 464-468
    • Spillane, J.B.1    Henderson, M.A.2
  • 28
    • 34250315214 scopus 로고    scopus 로고
    • Prostate cancer cells with stem cell characteristics reconstitute the original human tumor in vivo
    • Gu, G.; Yuan, J.; Wills, M. and Kasper, S. (2007) Prostate cancer cells with stem cell characteristics reconstitute the original human tumor in vivo. Cancer Res., 67(10), 4807-4815.
    • (2007) Cancer Res , vol.67 , Issue.10 , pp. 4807-4815
    • Gu, G.1    Yuan, J.2    Wills, M.3    Kasper, S.4
  • 29
    • 34250306257 scopus 로고    scopus 로고
    • Side population in human lung cancer cell lines and tumors is enriched with stem-like cancer cells
    • Ho, M.M.; Ng, A.V.; Lam, S. and Hung, J.Y. (2007) Side population in human lung cancer cell lines and tumors is enriched with stem-like cancer cells. Cancer Res., 67(10), 4827-4833.
    • (2007) Cancer Res , vol.67 , Issue.10 , pp. 4827-4833
    • Ho, M.M.1    Ng, A.V.2    Lam, S.3    Hung, J.Y.4
  • 30
    • 0034988303 scopus 로고    scopus 로고
    • Bone marrow stromal stem cells, Nature, biology, and potential applications
    • Bianco P, Riminucci M, Gronthos S and Robey PG. (2001) Bone marrow stromal stem cells, Nature, biology, and potential applications. Stem Cells, 19(3), 180-192.
    • (2001) Stem Cells , vol.19 , Issue.3 , pp. 180-192
    • Bianco, P.1    Riminucci, M.2    Gronthos, S.3    Robey, P.G.4
  • 31
    • 0033824164 scopus 로고    scopus 로고
    • Mesenchymal stem cells, Biology and potential clinical uses
    • Deans, R.A.; Moseley, A.B. (2000) Mesenchymal stem cells, Biology and potential clinical uses. Exp. Hematol., 28(8), 875-884.
    • (2000) Exp. Hematol , vol.28 , Issue.8 , pp. 875-884
    • Deans, R.A.1    Moseley, A.B.2
  • 32
    • 0034975453 scopus 로고    scopus 로고
    • Mesenchymal stem cells, building blocks for molecular medicine in the 21st century
    • Caplan, A.I. and Bruder, S.P. (2001) Mesenchymal stem cells, building blocks for molecular medicine in the 21st century. Trends Mol. Med., 7(6), 259-264.
    • (2001) Trends Mol. Med , vol.7 , Issue.6 , pp. 259-264
    • Caplan, A.I.1    Bruder, S.P.2
  • 33
    • 33751551658 scopus 로고    scopus 로고
    • The bone marrow constitutes a reservoir of pericyte progenitors
    • Lamagna, C. and Bergers, G. (2006) The bone marrow constitutes a reservoir of pericyte progenitors. J. Leukoc. Biol., 80(4), 677-681.
    • (2006) J. Leukoc. Biol , vol.80 , Issue.4 , pp. 677-681
    • Lamagna, C.1    Bergers, G.2
  • 34
    • 27644557532 scopus 로고    scopus 로고
    • The role of pericytes in blood-vessel formation and maintenance
    • Bergers G and Song S. (2005) The role of pericytes in blood-vessel formation and maintenance. Neuro-oncology, 7(4), 452-464.
    • (2005) Neuro-oncology , vol.7 , Issue.4 , pp. 452-464
    • Bergers, G.1    Song, S.2
  • 35
    • 39449107724 scopus 로고    scopus 로고
    • In vitro secreting profile of human mesenchymal stem cells
    • Schinkothe, T.; Bloch, W. and Schmidt, A. (2008) In vitro secreting profile of human mesenchymal stem cells. Stem Cells Dev., 17(1), 199-206.
    • (2008) Stem Cells Dev , vol.17 , Issue.1 , pp. 199-206
    • Schinkothe, T.1    Bloch, W.2    Schmidt, A.3
  • 36
    • 33745489036 scopus 로고    scopus 로고
    • Human bone marrow stromal cells express a distinct set of biologically functional chemokine receptors
    • Honczarenko, M.; Le, Y.; Swierkowski, M.; Ghiran, I.; Glodek, A.M. and Silberstein, L.E. (2006) Human bone marrow stromal cells express a distinct set of biologically functional chemokine receptors. Stem Cells, 24(4), 1030-1041.
    • (2006) Stem Cells , vol.24 , Issue.4 , pp. 1030-1041
    • Honczarenko, M.1    Le, Y.2    Swierkowski, M.3    Ghiran, I.4    Glodek, A.M.5    Silberstein, L.E.6
  • 37
    • 14944339174 scopus 로고    scopus 로고
    • Human mesenchymal stem cells alter antigen-presenting cell maturation and induce T-cell unresponsiveness
    • Beyth, S.; Borovsky, Z.; Mevorach, D.; Liebergall, M.; Gazit, Z., Aslan, H. Galun, E. and Rachmilewitz, J. (2005) Human mesenchymal stem cells alter antigen-presenting cell maturation and induce T-cell unresponsiveness. Blood, 105(5), 2214-2219.
    • (2005) Blood , vol.105 , Issue.5 , pp. 2214-2219
    • Beyth, S.1    Borovsky, Z.2    Mevorach, D.3    Liebergall, M.4    Gazit, Z.5    Aslan, H.6    Galun, E.7    Rachmilewitz, J.8
  • 38
    • 33745076513 scopus 로고    scopus 로고
    • Antigen-presenting property of mesenchymal stem cells occurs during a narrow window at low levels of interferon-gamma
    • Chan, J.L.; Tang, K.C.; Patel, A.P.; Bonilla, L.M.; Pierobon, N.; Ponzio, N.M. and Rameshwar, P. (2006) Antigen-presenting property of mesenchymal stem cells occurs during a narrow window at low levels of interferon-gamma. Blood, 107(12), 4817-4824.
    • (2006) Blood , vol.107 , Issue.12 , pp. 4817-4824
    • Chan, J.L.1    Tang, K.C.2    Patel, A.P.3    Bonilla, L.M.4    Pierobon, N.5    Ponzio, N.M.6    Rameshwar, P.7
  • 39
    • 0043245963 scopus 로고    scopus 로고
    • Highly efficient endosomal labeling of progenitor and stem cells with large magnetic particles allows magnetic resonance imaging of single cells
    • Hinds, K.A.; Hill, J.M.; Shapiro, E.M.; Laukkanen, M.O.; Silva, A.C.; Combs, C.A.; Varney, T.R.; Balaban, R.S.; Koretsky, A.P. and Dunbar, C.E. (2003) Highly efficient endosomal labeling of progenitor and stem cells with large magnetic particles allows magnetic resonance imaging of single cells. Blood, 102(3), 867-872.
    • (2003) Blood , vol.102 , Issue.3 , pp. 867-872
    • Hinds, K.A.1    Hill, J.M.2    Shapiro, E.M.3    Laukkanen, M.O.4    Silva, A.C.5    Combs, C.A.6    Varney, T.R.7    Balaban, R.S.8    Koretsky, A.P.9    Dunbar, C.E.10
  • 40
    • 20444458975 scopus 로고    scopus 로고
    • A paradoxical role for IFN-gamma in the immune properties of mesenchymal stem cells during viral challenge
    • Kang, H.S.; Habib, M.; Chan, J.; Abavana, C.; Potian, J.A.; Ponzio, N.M. and Rameshwar, P. (2005) A paradoxical role for IFN-gamma in the immune properties of mesenchymal stem cells during viral challenge. Exp. Hematol., 33(7), 796-803.
    • (2005) Exp. Hematol , vol.33 , Issue.7 , pp. 796-803
    • Kang, H.S.1    Habib, M.2    Chan, J.3    Abavana, C.4    Potian, J.A.5    Ponzio, N.M.6    Rameshwar, P.7
  • 41
    • 0141886188 scopus 로고    scopus 로고
    • Veto-Like activity of mesenchymal stem cells, Functional discrimination between cellular responses to alloantigens and recall antigens
    • Potian, J.A.; Aviv, H.; Ponzio, N.M.; Harrison, J.S. and Rameshwar, P. (2003) Veto-Like activity of mesenchymal stem cells, Functional discrimination between cellular responses to alloantigens and recall antigens. J. Immunol., 171(7), 3426-3434.
    • (2003) J. Immunol , vol.171 , Issue.7 , pp. 3426-3434
    • Potian, J.A.1    Aviv, H.2    Ponzio, N.M.3    Harrison, J.S.4    Rameshwar, P.5
  • 42
    • 32644438233 scopus 로고    scopus 로고
    • Mesenchymal stem cell-natural killer cell interactions, evidence that activated NK cells are capable of killing MSCs, whereas MSCs can inhibit IL-2-induced NK-cell proliferation
    • Spaggiari, G.M.; Capobianco, A.; Becchetti, S.; Mingari, M.C. and Moretta, L. (2006) Mesenchymal stem cell-natural killer cell interactions, evidence that activated NK cells are capable of killing MSCs, whereas MSCs can inhibit IL-2-induced NK-cell proliferation. Blood, 107(4), 1484-1490.
    • (2006) Blood , vol.107 , Issue.4 , pp. 1484-1490
    • Spaggiari, G.M.1    Capobianco, A.2    Becchetti, S.3    Mingari, M.C.4    Moretta, L.5
  • 43
    • 34547451080 scopus 로고    scopus 로고
    • Human bone marrow stromal cells enhance breast cancer cell growth rates in a cell line-dependent manner when evaluated in 3D tumor environments
    • Sasser, A.K.; Mundy, B.L.; Smith, K.M.; Studebaker, A.W.; Axel, A.E.; Haidet, A.M. Fernandez, S.A. and Hall, B.M. (2007) Human bone marrow stromal cells enhance breast cancer cell growth rates in a cell line-dependent manner when evaluated in 3D tumor environments. Cancer Lett., 254(2), 255-264.
    • (2007) Cancer Lett , vol.254 , Issue.2 , pp. 255-264
    • Sasser, A.K.1    Mundy, B.L.2    Smith, K.M.3    Studebaker, A.W.4    Axel, A.E.5    Haidet, A.M.6    Fernandez, S.A.7    Hall, B.M.8
  • 44
    • 33847793202 scopus 로고    scopus 로고
    • Gene silencing by small regulatory RNAs in mammalian cells
    • Scherr, M. and Eder, M. (2007) Gene silencing by small regulatory RNAs in mammalian cells. Cell Cycle 6(4), 444-449.
    • (2007) Cell Cycle , vol.6 , Issue.4 , pp. 444-449
    • Scherr, M.1    Eder, M.2
  • 45
    • 34247884486 scopus 로고    scopus 로고
    • Regulatory small RNAs in plants
    • Johnson, C. and Sundaresan, V. (2007) Regulatory small RNAs in plants. EXS, 97, 99-113.
    • (2007) EXS , vol.97 , pp. 99-113
    • Johnson, C.1    Sundaresan, V.2
  • 46
    • 11844278458 scopus 로고    scopus 로고
    • Conserved sed piring, often flanked by adenosines, indicates that tousands of hman genes are microRNA trgets
    • Lewis, B.P.; Burge, C.B. and Bartel, D.P. (2005) Conserved sed piring, often flanked by adenosines, indicates that tousands of hman genes are microRNA trgets. Cell, 120(1), 15-20.
    • (2005) Cell , vol.120 , Issue.1 , pp. 15-20
    • Lewis, B.P.1    Burge, C.B.2    Bartel, D.P.3
  • 47
    • 33750370444 scopus 로고    scopus 로고
    • MicroRNA signatures in human cancers
    • Calin, G.A. and Croce, C.M. (2006) MicroRNA signatures in human cancers. Nat. Rev. Cancer, 6(11), 857-866.
    • (2006) Nat. Rev. Cancer , vol.6 , Issue.11 , pp. 857-866
    • Calin, G.A.1    Croce, C.M.2
  • 48
    • 34248682652 scopus 로고    scopus 로고
    • MicroRNAs and regenerative medicine
    • Yang, Z. and Wu, J. (2007) MicroRNAs and regenerative medicine. DNA Cell. Biol., 26(4), 257-264.
    • (2007) DNA Cell. Biol , vol.26 , Issue.4 , pp. 257-264
    • Yang, Z.1    Wu, J.2
  • 50
    • 33645002735 scopus 로고    scopus 로고
    • Life cycle of connexins in health and disease
    • Laird, D.W. (2006) Life cycle of connexins in health and disease. Biochem. J., 394(Pt 3), 527-543.
    • (2006) Biochem. J , vol.394 , Issue.PART 3 , pp. 527-543
    • Laird, D.W.1
  • 51
    • 17344390158 scopus 로고    scopus 로고
    • Plasma membrane channels formed by connexins, Their regulation and functions
    • Seez, J.C.; Berthoud, V.M.; Branes, M.C.; Martinez, A.D. and Beyer, E.C. (2003) Plasma membrane channels formed by connexins, Their regulation and functions. Physiol. Rev., 83(4), 1359-1400.
    • (2003) Physiol. Rev , vol.83 , Issue.4 , pp. 1359-1400
    • Seez, J.C.1    Berthoud, V.M.2    Branes, M.C.3    Martinez, A.D.4    Beyer, E.C.5
  • 52
    • 0029827827 scopus 로고    scopus 로고
    • Gap junction genes Cx26 and Cx43 individually suppress the cancer phenotype of human mammary carcinoma cells and restore differentiation potential
    • Hirschi, K.K.; Xu, C.E.; Tsukamoto, T. and Sager, R. (1996) Gap junction genes Cx26 and Cx43 individually suppress the cancer phenotype of human mammary carcinoma cells and restore differentiation potential. Cell Growth Differ., 7(7), 861-870.
    • (1996) Cell Growth Differ , vol.7 , Issue.7 , pp. 861-870
    • Hirschi, K.K.1    Xu, C.E.2    Tsukamoto, T.3    Sager, R.4
  • 54
    • 0029916722 scopus 로고    scopus 로고
    • Connexin Expression and GAP junctions in the mammary gland
    • Monaghan, P. and Moss, D. (1996) Connexin Expression and GAP junctions in the mammary gland. Cell Biol. Intl., 20(2), 121-125.
    • (1996) Cell Biol. Intl , vol.20 , Issue.2 , pp. 121-125
    • Monaghan, P.1    Moss, D.2
  • 55
    • 0031908039 scopus 로고    scopus 로고
    • Expression of gap junction proteins connexin 26 and connexin 43 in normal human breast and in breast tumours
    • Jamieson, S.; Going, J.J.; D'Arcy, R. and George, W.D. (1998) Expression of gap junction proteins connexin 26 and connexin 43 in normal human breast and in breast tumours. J. Pathol., 184(1), 37-43.
    • (1998) J. Pathol , vol.184 , Issue.1 , pp. 37-43
    • Jamieson, S.1    Going, J.J.2    D'Arcy, R.3    George, W.D.4
  • 56
    • 0026694158 scopus 로고
    • Expression of Cx26, Cx32 and Cx43 gap junction proteins in normal and neoplastic human tissues
    • Wilgenbus, K.K.; Kirkpatrick, C.J.; Knuechel, R.; Willecke, K. and Traub, O. (1992) Expression of Cx26, Cx32 and Cx43 gap junction proteins in normal and neoplastic human tissues. Intl. J. Cancer, 51(4), 522-529.
    • (1992) Intl. J. Cancer , vol.51 , Issue.4 , pp. 522-529
    • Wilgenbus, K.K.1    Kirkpatrick, C.J.2    Knuechel, R.3    Willecke, K.4    Traub, O.5
  • 57
    • 16844375853 scopus 로고    scopus 로고
    • Down-regulation of Cx43 by retroviral delivery of small interfering RNA promotes an aggressive breast cancer cell phenotype
    • Shao, Q.; Wang, H.; McLachlan, E.; Veitch, G.I.L. and Laird, D.W. (2005) Down-regulation of Cx43 by retroviral delivery of small interfering RNA promotes an aggressive breast cancer cell phenotype. Cancer Res., 65(7), 2705-2711.
    • (2005) Cancer Res , vol.65 , Issue.7 , pp. 2705-2711
    • Shao, Q.1    Wang, H.2    McLachlan, E.3    Veitch, G.I.L.4    Laird, D.W.5
  • 58
    • 42449155085 scopus 로고    scopus 로고
    • Alterations in Cx43 and OB-cadherin affect breast cancer cell metastatic potential
    • Li, Z.; Zhou, Z. and Donahue, H.J. (2008) Alterations in Cx43 and OB-cadherin affect breast cancer cell metastatic potential. Clin. Exp. Metastasis, 25(3), 265-272.
    • (2008) Clin. Exp. Metastasis , vol.25 , Issue.3 , pp. 265-272
    • Li, Z.1    Zhou, Z.2    Donahue, H.J.3
  • 59
    • 36249001676 scopus 로고    scopus 로고
    • Connexins and gap junctions in mammary gland development and breast cancer progression
    • McLachlan, E.; Shao, Q. and Laird, D. (2007) Connexins and gap junctions in mammary gland development and breast cancer progression. J. Memb. Biol., 218(1), 107-121.
    • (2007) J. Memb. Biol , vol.218 , Issue.1 , pp. 107-121
    • McLachlan, E.1    Shao, Q.2    Laird, D.3
  • 60
    • 40649094015 scopus 로고    scopus 로고
    • Connexin26 expression is associated with aggressive phenotype in human papillary and follicular thyroid cancers
    • Naoi, Y.; Miyoshi, Y.; Taguchi, T.; Kim, S.J.; Arai, T.; Maruyama, N.; Tamaki Y. And Noguchi S. (2008) Connexin26 expression is associated with aggressive phenotype in human papillary and follicular thyroid cancers. Cancer Lett., 262(2), 248-256.
    • (2008) Cancer Lett , vol.262 , Issue.2 , pp. 248-256
    • Naoi, Y.1    Miyoshi, Y.2    Taguchi, T.3    Kim, S.J.4    Arai, T.5    Maruyama, N.6    Tamaki, Y.7    And Noguchi, S.8
  • 63
    • 33750536492 scopus 로고    scopus 로고
    • Cx26 inhibits breast MDA-MB-435 cell tumorigenic properties by a gap junctional intercellular communication-independent mechanism
    • Kalra, J.; Shao, Q.; Qin, H.; Thomas, T.; Aoui-Jamali, M.A. and Laird, D.W. (2006) Cx26 inhibits breast MDA-MB-435 cell tumorigenic properties by a gap junctional intercellular communication-independent mechanism. Carcinogenesis, 27(12), 2528-2537.
    • (2006) Carcinogenesis , vol.27 , Issue.12 , pp. 2528-2537
    • Kalra, J.1    Shao, Q.2    Qin, H.3    Thomas, T.4    Aoui-Jamali, M.A.5    Laird, D.W.6
  • 65
    • 33750572911 scopus 로고    scopus 로고
    • Connexins act as Tumor Suppressors in three-dimensional mammary cell organoids by regulating differentiation and angiogenesis
    • McLachlan, E., Shao, Q., Wang, H.l., Langlois, S. and Laird, D.W. (2006) Connexins act as Tumor Suppressors in three-dimensional mammary cell organoids by regulating differentiation and angiogenesis. Cancer Res., 66(20), 9886-9894.
    • (2006) Cancer Res , vol.66 , Issue.20 , pp. 9886-9894
    • McLachlan, E.1    Shao, Q.2    Wang, H.L.3    Langlois, S.4    Laird, D.W.5
  • 66
    • 34249041688 scopus 로고    scopus 로고
    • Symmetric division of cancer stem cells - a key mechanism in tumor growth that should be targeted in future therapeutic approaches
    • Boman, B.M.; Wicha, M.S.; Fields, J.Z. and Runquist, O.A. (2007) Symmetric division of cancer stem cells - a key mechanism in tumor growth that should be targeted in future therapeutic approaches. Clin. Pharmacol. Ther., 81(6), 893-898.
    • (2007) Clin. Pharmacol. Ther , vol.81 , Issue.6 , pp. 893-898
    • Boman, B.M.1    Wicha, M.S.2    Fields, J.Z.3    Runquist, O.A.4
  • 67
    • 34247521438 scopus 로고    scopus 로고
    • Priming the 'soil' for breast cancer metastasis, the pre-metastatic niche
    • Psaila, B.; Kaplan, R.N.; Port, E.R. and Lyden, D. (2006) Priming the 'soil' for breast cancer metastasis, the pre-metastatic niche. Breast Dis., 26, 65-74.
    • (2006) Breast Dis , vol.26 , pp. 65-74
    • Psaila, B.1    Kaplan, R.N.2    Port, E.R.3    Lyden, D.4
  • 68
    • 33846044750 scopus 로고    scopus 로고
    • Bone marrow cells in the 'pre-metastatic niche', within bone and beyond
    • Kaplan, R.; Psaila, B. and Lyden, D. (2006) Bone marrow cells in the 'pre-metastatic niche', within bone and beyond. Cancer Metastasis Rev., 25(4), 521-529.
    • (2006) Cancer Metastasis Rev , vol.25 , Issue.4 , pp. 521-529
    • Kaplan, R.1    Psaila, B.2    Lyden, D.3
  • 69
    • 33846798072 scopus 로고    scopus 로고
    • Niche-to-niche migration of bone-marrow-derived cells
    • Kaplan, R.N.; Psaila, B. and Lyden, D. (2007) Niche-to-niche migration of bone-marrow-derived cells. Trends Mol. Med., 13(2), 72-81.
    • (2007) Trends Mol. Med , vol.13 , Issue.2 , pp. 72-81
    • Kaplan, R.N.1    Psaila, B.2    Lyden, D.3
  • 70
    • 28644448343 scopus 로고    scopus 로고
    • Cancer biology, Emissaries set up new sites
    • Steeg, P.S. (2005) Cancer biology, Emissaries set up new sites. Nature, 438(7069), 750-751.
    • (2005) Nature , vol.438 , Issue.7069 , pp. 750-751
    • Steeg, P.S.1
  • 72
    • 65949097167 scopus 로고    scopus 로고
    • Improving the interpretation of bone marrow imaging in cancer patients
    • Ollivier, L.; Gerber, S.; Vanel, D.; Brisse, H. and Leclere, J. (2006) Improving the interpretation of bone marrow imaging in cancer patients. Cancer Imag., 6194-198.
    • (2006) Cancer Imag , pp. 6194-6198
    • Ollivier, L.1    Gerber, S.2    Vanel, D.3    Brisse, H.4    Leclere, J.5
  • 73
    • 13444268127 scopus 로고    scopus 로고
    • Minn, A.J.; Kang, Y.; Serganova, I.; Gupta, G.P.; Giri, D.D.; Doubrovin, M. (2005) Ponomarev. V., Gerald, W.L., Blasberg, R. and Massagué. J. Distinct organ-specific metastatic potential of individual breast cancer cells and primary tumors. J. Clin. Invest. 115(1), 44-55.
    • Minn, A.J.; Kang, Y.; Serganova, I.; Gupta, G.P.; Giri, D.D.; Doubrovin, M. (2005) Ponomarev. V., Gerald, W.L., Blasberg, R. and Massagué. J. Distinct organ-specific metastatic potential of individual breast cancer cells and primary tumors. J. Clin. Invest. 115(1), 44-55.


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