The stem cell niche in health and leukemic disease

Best Practice and Research in Clinical Haematology

Volumn 20, Issue 1, 2007, Pages 19-27

  Scadden, David T ^a,b  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HARVARD STEM CELL INSTITUTE   (United States)

Author keywords

leukemia; microenvironment; stem cell niches; stem cells

Indexed keywords

CALCIUM SENSING RECEPTOR; CINACALCET; CYCLOPHOSPHAMIDE; GRANULOCYTE COLONY STIMULATING FACTOR; NATALIZUMAB; NEW DRUG; OSTABOLIN C; OSTEOPONTIN; PARATHYROID HORMONE; PARATHYROID HORMONE[1-34]; UNCLASSIFIED DRUG;

ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION; AUTOLOGOUS HEMATOPOIETIC STEM CELL TRANSPLANTATION; BONE MARROW; BRAIN; CANCER STEM CELL; CLINICAL TRIAL; COMBINATION CHEMOTHERAPY; DOSE RESPONSE; EXTRACELLULAR MATRIX; HEMATOPOIESIS; HUMAN; HYPERCALCEMIA; INTESTINE; LEUKEMIA; LEUKEMOGENESIS; MICROENVIRONMENT; MONOTHERAPY; MULTIPLE SCLEROSIS; NONHUMAN; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION; SKIN; STEM CELL MOBILIZATION;

ANIMALS; DISEASE MODELS, ANIMAL; EXTRACELLULAR MATRIX PROTEINS; GENE EXPRESSION REGULATION, LEUKEMIC; HUMANS; LEUKEMIA; MICE; TUMOR STEM CELLS;

EID: 33847227974     PISSN: 15216926     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.beha.2006.11.001     Document Type: Review

References (21)

1. Xie T., and Spradling A.C. A niche maintaining germ line stem cells in the Drosophila ovary. Science 290 (2000) 328-330
2. Kiger A.A., White-Cooper H., and Fuller M.T. Somatic support cells restrict germline stem cell self-renewal and promote differentiation. Nature 407 (2000) 750-754
3. Crittenden S.L., Bernstein D.S., Bachorik J.L., et al. A conserved RNA-binding protein controls germline stem cells in Caenorhabditis elegans. Nature 417 (2002) 660-663
4. Spradling A., Drummond-Barbosa D., and Kai T. Stem cells find their niche. Nature 414 (2001) 98-104
5. Udani V.M. The continuum of stem cell transdifferentiation: possibility of hematopoietic stem cell plasticity with concurrent CD45 expression. Stem Cells and Development 15 (2006) 1-3
6. Jones P.H., and Watt F.M. Separation of human epidermal stem cells from transit amplifying cells on the basis of differences in integrin function and expression. Cell 73 (1993) 713-724
7. Jensen U.B., Lowell S., and Watt F.M. The spatial relationship between stem cells and their progeny in the basal layer of human epidermis: a new view based on whole-mount labelling and lineage analysis. Development 126 (1999) 2409-2418
8. Ormestad M., Astorga J., Landgren H., et al. Foxf1 and Foxf2 control murine gut development by limiting mesenchymal Wnt signaling and promoting extracellular matrix production. Development 133 (2006) 833-843
9. Nilsson S.K., Johnston H.M., Whitty G.A., et al. Osteopontin, a key component of the hematopoietic stem cell niche and regulator of primitive hematopoietic progenitor cells. Blood 106 (2005) 1232-1239
10. Nilsson S.K., Dooner M.S., Tiarks C.Y., et al. Potential and distribution of transplanted hematopoietic stem cells in a nonablated mouse model. Blood 89 (1997) 4013-4020
11. Kiel M.J., Yilmaz O.H., Iwashita T., et al. SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells. Cell 121 (2005) 1109-1121
12. Calvi L.M., Adams G.B., Weibrecht K.W., et al. Osteoblastic cells regulate the haematopoietic stem cell niche. Nature 425 (2003) 841-846
13. Zhang J., Niu C., Ye L., et al. Identification of the haematopoietic stem cell niche and control of the niche size. Nature 425 (2003) 836-841
14. Arai F., Hirao A., and Suda T. Regulation of hematopoietic stem cells by the niche. Trends in Cardiovascular Medicine 15 (2005) 75-79
15. Gronthos S., Zannettino A.C., Hay S.J., et al. Molecular and cellular characterisation of highly purified stromal stem cells derived from human bone marrow. Journal of Cell Science 116 (2003) 1827-1835
16. Stier S., Ko Y., Forkert R., et al. Osteopontin is a hematopoietic stem cell niche component that negatively regulates stem cell pool size. The Journal of Experimental Medicine 201 (2005) 1781-1791
17. McNeil S.E., Hobson S.A., Nipper V., et al. Functional calcium-sensing receptors in rat fibroblasts are required for activation of SRC kinase and mitogen-activated protein kinase in response to extracellular calcium. The Journal of Biological Chemistry 273 (1998) 1114-1120
18. Adams G.B., Chabner K.T., Alley I.R., et al. Stem cell engraftment at the endosteal niche is specified by the calcium-sensing receptor. Nature 439 (2006) 599-603
19. Ballen K.B., Shpall E.J., Avigan D., et al. Parathyroid hormone may improve autologous stem cell mobilization va the stem cell niche. Blood 106 (2005) 557a (abstract)
20. Reya T., Morrison S.J., Clarke M.F., et al. Stem cells, cancer, and cancer stem cells. Nature 414 (2001) 105-111
21. Onuma E., Tsunenari T., Saito H., et al. Parathyroid hormone-related protein (PTHrP) as a causative factor of cancer-associated wasting: possible involvement of PTHrP in the repression of locomotor activity in rats bearing human tumor xenografts. International Journal of Cancer 116 (2005) 471-478