Expansion of host range as a driving force in the evolution of Toxoplasma

Memorias do Instituto Oswaldo Cruz

Volumn 104, Issue 2, 2009, Pages 179-184

  Boothroyd, John C ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Antigens; Genetics; Pathogenesis; Recombination; Rhoptries; Virulence

Indexed keywords

ANIMALIA; MUS; TOXOPLASMA; TOXOPLASMA GONDII;

EID: 65549103509     PISSN: 00740276     EISSN: 16788060     Source Type: Journal    
DOI: 10.1590/S0074-02762009000200009     Document Type: Article

References (34)

1. Ajzenberg D, Banuls AL, Su C, Dumetre A, Demar M, Carme B, Darde ML 2004. Genetic diversity, clonality and sexuality in Toxoplasma gondii. Int J Parasitol 34: 1185-1196.
2. Ajzenberg D, Banuls AL, Tibayrenc M, Darde ML 2002. Microsatellite analysis of Toxoplasma gondii shows considerable polymorphism structured into two main clonal groups. Int J Parasitol 32: 27-38.
3. Alexander DL, Mital J, Ward GE, Bradley P, Boothroyd JC 2005. Identification of the moving junction complex of Toxoplasma gondii: a collaboration between distinct secretory organelles. PLoS Pathog 1: e17.
4. Blanchard N, Gonzalez F, Schaeffer M, Joncker NT, Cheng T, Shastri AJ, Robey EA, Shastri N 2008. Immunodominant, protective response to the parasite Toxoplasma gondii requires antigen processing in the endoplasmic reticulum. Nat Immunol 9: 937-944.
5. Boyle JP, Rajasekar B, Saeij JP, Ajioka JW, Berriman M, Paulsen I, Roos DS, Sibley LD, White MW, Boothroyd JC 2006. Just one cross appears capable of dramatically altering the population biology of a eukaryotic pathogen like Toxoplasma gondii. Proc Natl Acad Sci USA 103: 10514-10519.
6. Cleary MD, Singh U, Blader IJ, Brewer JL, Boothroyd JC 2002. Toxoplasma gondii asexual development: identification of developmentally regulated genes and distinct patterns of gene expression. Eukaryot Cell 1: 329-340.
7. Darde ML, Bouteille B, Pestre-Alexandre M 1988. Isoenzymic characterization of seven strains of Toxoplasma gondii by isoelectrofocusing in polyacrylamide gels. Am J Trop Med Hyg 39: 551-558.
8. Dubey JP, Speer CA, Shen SK, Kwok OC, Blixt JA 1997. Oocyst-induced murine toxoplasmosis: life cycle, pathogenicity and stage conversion in mice fed Toxoplasma gondii oocysts. J Parasitol 83: 870-882.
9. Dzierszinski F, Mortuaire M, Cesbron-Delauw MF, Tomavo S 2000. Targeted disruption of the glycosylphosphatidylinositol-anchored surface antigen SAG3 gene in Toxoplasma gondii decreases host cell adhesion and drastically reduces virulence in mice. Mol Microbiol 37: 574-582.
10. El Hajj H, Demey E, Poncet J, Lebrun M, Wu B, Galeotti N, Fourmaux MN, Mercereau-Puijalon O, Vial H, Labesse G, Dubremetz JF 2006. The ROP2 family of Toxoplasma gondii rhoptry proteins: proteomic and genomic characterization and molecular modeling. Proteomics 6: 5773-5784.
11. El Hajj H, Lebrun M, Arold ST, Vial H, Labesse G, Dubremetz JF 2007. ROP18 is a rhoptry kinase controlling the intracellular proliferation of Toxoplasma gondii. PLoS Pathog 3: e14.
12. Gilbert LA, Ravindran S, Turetzky JM, Boothroyd JC, Bradley PJ 2007. Toxoplasma gondii targets a protein phosphatase 2C to the nuclei of infected host cells. Eukaryot Cell 6: 73-83.
13. Grigg ME, Bonnefoy S, Hehl AB, Suzuki Y, Boothroyd JC 2001. Success and virulence in Toxoplasma as the result of sexual recombination between two distinct ancestries. Science 294: 161-165.
14. Hakansson S, Charron AJ, Sibley, LD 2001. Toxoplasma evacuoles: a two-step process of secretion and fusion forms the parasitophorous vacuole. Embo J 20: 3132-3144.
15. Howe DK, Sibley LD 1995. Toxoplasma gondii comprises three clonal lineages: correlation of parasite genotype with human disease. J Infect Dis 172: 1561-1566.
16. Jung C, Lee CY, Grigg ME 2004. The SRS superfamily of Toxoplasma surface proteins. Int J Parasitol 34: 285-296.
17. Khan A, Bohme U, Kelly KA, Adlem E, Brooks K, Simmonds M, Mungall K, Quail MA, Arrowsmith C, Chillingworth T, Churcher C, Harris D, Collins M, Fosker N, Fraser A, Hance Z, Jagels K, Moule S, Murphy L, O'Neil S, Rajandream MA, Saunders D, Seeger K, Whitehead S, Mayr T, Xuan X, Watanabe J, Suzuki Y, Wakaguri H, Sugano S, Sugimoto C, Paulsen I, Mackey AJ, Roos DS, Hall N, Berriman M, Barrell B, Sibley LD, Ajioka JW 2006. Common inheritance of chromosome Ia associated with clonal expansion of Toxoplasma gondii. Genome Res 16: 1119-1125.
18. Khan A, Fux B, Su C, Dubey JP, Darde ML, Ajioka JW, Rosenthal BM, Sibley LD 2007. Recent transcontinental sweep of Toxoplasma gondii driven by a single monomorphic chromosome. Proc Natl Acad Sci USA 104: 14872-14877.
19. Kim SK, Boothroyd JC 2005. Stage-specific expression of surface antigens by Toxoplasma gondii as a mechanism to facilitate parasite persistence. J Immunol 174: 8038-8048.
20. Kim SK, Karasov A, Boothroyd JC 2007. Bradyzoite-specific surface antigen SRS9 plays a role in maintaining Toxoplasma gondii persistence in the brain and in host control of parasite replication in the intestine. Infect Immun 75: 1626-1634.
21. Kimata I, Tanabe K 1987. Secretion by Toxoplasma gondii of an antigen that appears to become associated with the parasitophorous vacuole membrane upon invasion of the host cell. J Cell Sci 88: 231-239.
22. Lebrun M, Michelin A, El Hajj H, Poncet J, Bradley PJ, Vial H, Dubremetz JF 2005. The rhoptry neck protein RON4 re-localizes at the moving junction during Toxoplasma gondii invasion. Cell Microbiol 7: 1823-1833.
23. Lehmann T, Marcet PL, Graham DH, Dahl ER, Dubey JP 2006. Globalization and the population structure of Toxoplasma gondii. Proc Natl Acad Sci USA 103: 11423-11428.
24. Lekutis C, Ferguson DJ, Grigg ME, Camps M, Boothroyd JC 2001. Surface antigens of Toxoplasma gondii: variations on a theme. Int J Parasitol 31: 1285-1292.
25. Miller MA, Grigg ME, Kreuder C, James ER, Melli AC, Crosbie PR, Jessup DA, Boothroyd JC, Brownstein D, Conrad PA 2004. An unusual genotype of Toxoplasma gondii is common in California sea otters (Enhydra lutris nereis) and is a cause of mortality. Int J Parasitol 34: 275-284.
26. Mineo JR, Kasper LH 1994. Attachment of Toxoplasma gondii to host cells involves major surface protein, SAG-1 (P30). Exp Parasitol 79: 11-20.
27. Pollard AM, Onatolu KN, Hiller L, Haldar K, Knoll LJ 2008. Highly polymorphic family of glycosylphosphatidylinositol-anchored surface antigens with evidence of developmental regulation in Toxoplasma gondii. Infect Immun 76: 103-110.
28. Rachinel N, Buzoni-Gatel D, Dutta C, Mennechet FJ, Luangsay S, Minns LA, Grigg ME, Tomavo S, Boothroyd JC, Kasper LH 2004. The induction of acute ileitis by a single microbial antigen of Toxoplasma gondii. J Immunol 173: 2725-2735.
29. Radke JR, Gubbels MJ, Jerome ME, Radke JB, Striepen B, White MW 2004. Identification of a sporozoite-specific member of the Toxoplasma SAG superfamily via genetic complementation. Mol Microbiol 52: 93-105.
30. Saeij JP, Boyle JP, Coller S, Taylor S, Sibley LD, Brooke-Powell ET, Ajioka JW, Boothroyd JC 2006. Polymorphic secreted kinases are key virulence factors in toxoplasmosis. Science 314: 1780-1783.
31. Saeij JP, Coller S, Boyle JP, Jerome ME, White MW, Boothroyd JC 2007. Toxoplasma co-opts host gene expression by injection of a polymorphic kinase homologue. Nature 445: 324-327.
32. Sibley LD, Ajioka JW 2008. Population structure of Toxoplasma gondii: clonal expansion driven by infrequent recombination and selective sweeps. Annu Rev Microbiol 62: 329-351.
33. Sibley LD, Boothroyd JC 1992. Virulent strains of Toxoplasma gondii comprise a single clonal lineage. Nature 359: 82-85.
34. Taylor S, Barragan A, Su C, Fux B, Fentress SJ, Tang K, Beatty WL, Hajj HE, Jerome M, Behnke MS, White M, Wootton JC, Sibley LD 2006. A secreted serine-threonine kinase determines virulence in the eukaryotic pathogen Toxoplasma gondii. Science 314: 1776-1780.