Targeted disruption of the glycosylphosphatidylinositol-anchored surface antigen SAG3 gene in Toxoplasma gondii decreases host cell adhesion and drastically reduces virulence in mice

Molecular Microbiology

Volumn 37, Issue 3, 2000, Pages 574-582

  Dzierszinski, Florence ^a   Mortuaire, Marlène ^a   Cesbron Delauw, Marie France ^b   Tomavo, Stanislas ^a  

^a UNIVERSITÉ DES SCIENCES ET TECHNOLOGIES DE LILLE   (France)

^b INSTITUT DE BIOLOGIE DE LILLE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOSYLPHOSPHATIDYLINOSITOL; MEMBRANE ANTIGEN; PARASITE ANTIGEN; MEMBRANE PROTEIN; PROTOZOAL PROTEIN; SAG3 PROTEIN, TOXOPLASMA GONDII;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL ADHESION; CONTROLLED STUDY; GENE DISRUPTION; GENETIC CONSERVATION; HOST PARASITE INTERACTION; LIGAND BINDING; MORTALITY; MOUSE; MUTANT; NONHUMAN; PARASITE VIRULENCE; PRIORITY JOURNAL; TOXOPLASMA GONDII; ANIMAL; ANIMAL PARASITOSIS; GENE EXPRESSION REGULATION; GENE TARGETING; GENETICS; PATHOGENICITY; PATHOLOGY; TOXOPLASMA; VIRULENCE;

ANIMALIA; MAMMALIA; PROTOZOA; TOXOPLASMA GONDII;

ANIMALS; ANTIGENS, PROTOZOAN; ANTIGENS, SURFACE; CELL ADHESION; GENE EXPRESSION REGULATION; GENE TARGETING; GLYCOSYLPHOSPHATIDYLINOSITOLS; MEMBRANE GLYCOPROTEINS; MICE; PROTOZOAN PROTEINS; TOXOPLASMA; TOXOPLASMOSIS, ANIMAL; VIRULENCE;

EID: 0033624164     PISSN: 0950382X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2958.2000.02014.x     Document Type: Article

References (11)

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