Acute Liver Failure: Managing Coagulopathy and the Bleeding Diathesis

Transplantation Proceedings

Volumn 41, Issue 4, 2009, Pages 1256-1259

  De Gasperi, A ^a   Corti, A ^a   Mazza, E ^a   Prosperi, M ^a   Amici, O ^a   Bettinelli, L ^a  

^a OSPEDALE NIGUARDA CA GRANDA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ANTICOAGULANT AGENT; ANTIFIBRINOLYTIC AGENT; BLOOD CLOTTING FACTOR 10; BLOOD CLOTTING FACTOR 5; BLOOD CLOTTING FACTOR 7; FRESH FROZEN PLASMA; PARACETAMOL; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROTHROMBIN; RECOMBINANT BLOOD CLOTTING FACTOR 7A; TISSUE PLASMINOGEN ACTIVATOR;

ADULT; ARTICLE; BLEEDING TENDENCY; BLOOD CLOTTING; BLOOD CLOTTING DISORDER; COMORBIDITY; CRYOPRECIPITATE; DISSEMINATED INTRAVASCULAR CLOTTING; FIBRINOLYSIS; HEMOSTASIS; HUMAN; HYPOFIBRINOGENEMIA; LIVER FAILURE; LIVER TRANSPLANTATION; PLASMAPHERESIS; PRIORITY JOURNAL; PROTHROMBIN TIME; QUANTITATIVE ANALYSIS; THROMBOCYTE TRANSFUSION; TREATMENT INDICATION; BLOOD COAGULATION DISORDERS; COMPLICATION; HEMORRHAGE; LIVER FAILURE, ACUTE; PATHOPHYSIOLOGY;

ANTICOAGULANTS; BLOOD COAGULATION DISORDERS; HEMORRHAGE; HUMANS; LIVER FAILURE, ACUTE; LIVER TRANSPLANTATION;

EID: 65549100948     PISSN: 00411345     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.transproceed.2009.03.007     Document Type: Article

References (20)

1. Stravitz R.T., Kramer A.H., Davern T., et al. Intensive care of patients with acute liver failure: recommendations of the US: Acute Liver Failure Study Group. Crit Care Med 35 (2007) 2498
2. O'Grady J. Acute liver failure. Postgrad Med J 81 (2005) 148
3. Stravitz R.T. Critical management decision in patients with acute liver failure. Chest Chest 134 (2008) 1092
4. Auzinger G., and Wendon J. Intensive care management of acute liver failure. Curr Opin Crit Care 14 (2008) 179
5. Khashab M., Tecton J., and Kuo P.W. Epidemiology of acute liver failure. Curr Gastroenterol Rep 9 (2007) 66
6. Jalan R. Acute liver failure: current management and future prospects. J Hepatol 42 (2005) S115
7. Hoofnagle J.H., Carithers Jr. R.L., Shapiro C., et al. Fulminant hepatic failure: summary of a workshop. Hepatology 21 (1995) 240
8. Han M.L.K., and Hyzy R. Advances in critical care management of hepatic failure. Crit Care Med 34 (2006) S225
9. Lisman T., and Leebeek F. Hemostatic alterations in liver disease: a review on pathophysiology, clinical consequences, and treatment. Dig Surg 24 (2007) 250
10. Bismuth H., Samuel D., Castaing D., et al. Orthotopic liver transplantation in fulminant and subfulminant hepatitis. The Paul Brousse experience. Ann Surg 222 (1995) 109
11. O'Grady J.G., Alexander G.J., Hayllar K.M., et al. Early indicators of prognosis in fulminant hepatic failure. Gastroenterology 97 (1989) 439
12. Elinav E., Ben-Dov I., Hai-Am E., et al. The predictive value of admission and follow up factor V and VII levels in patients with acute hepatitis and coagulopathy. J Hepatol 42 (2005) 82
13. Munoz S.J., Reddy R.K., and Lee W. The coagulopathy of acute liver failure and implications for intracranial pressure monitoring. Neurocrit Care 9 (2008) 103-107
14. Senzolo M., Burra P., Cholongitas E., et al. New insights into the coagulopathy of liver disease and liver transplantation. World J Gastroenterol 12 (2006) 7725
15. Kerr R. New insights into haemostasis in liver failure. Blood Coag Fibrin 14 (2003) S43
16. Szczepiorkowski Z.M., Bandarenko N., Kim C.H., et al. Guidelines on the use of therapeutic apheresis in clinical practice-evidence-based approach from the Apheresis Applications Committee of the American Society for Apheresis. J Clin Apher 22 (2007) 106
17. Shami V., Caldwell S., and Hespenheide E. Recombinant activated factor VII for the coagulopathy of fulminant hepatic failure compared with conventional therapy. Liver Transpl 9 (2003) 138
18. Caldwell S.H., Chang C., and Macik B.G. Recombinant activated factor VII (rFVIIa) as a hemostatic agent in liver disease: a break from convention in need of controlled trials. Hepatology 39 (2004) 592
19. De Gasperi A. Intraoperative use of recombinant activated factor VII (rFVIIa). Minerva Anestesiol 72 (2006) 489
20. Pavese P., Bonadona A., Beaubien J., et al. FVIIa corrects the coagulopathy of fulminant hepatic failure but may be associated with thrombosis: a report of four cases. Can J Anaesth 52 (2005) 26