Antibacterial activity of berberine-NorA pump inhibitor hybrids with a methylene ether linking group

Bioorganic and Medicinal Chemistry

Volumn 17, Issue 11, 2009, Pages 3866-3872

  Samosorn, Siritron ^a   Tanwirat, Bongkot ^a   Muhamad, Nussara ^a   Casadei, Gabriele ^b   Tomkiewicz, Danuta ^b   Lewis, Kim ^b   Suksamrarn, Apichart ^c   Prammananan, Therdsak ^d   Gornall, Karina C ^e   Beck, Jennifer L ^e   Bremner, John B ^e  

^a SRINAKHARINWIROT UNIVERSITY   (Thailand)

^b NORTHEASTERN UNIVERSITY   (United States)

^c RAMKHAMHAENG UNIVERSITY   (Thailand)

^d NATIONAL SCIENCE AND TECHNOLOGY DEVELOPMENT AGENCY   (Thailand)

^e UNIVERSITY OF WOLLONGONG   (Australia)

Author keywords

13 Substituted berberine; Antibacterial; Dual action; Hybrid; NorA efflux pump inhibitors

Indexed keywords

5 NITRO 2 PHENYL 1H INDOLE; 9,10 DIMETHOXY 13 [2 (5 NITRO 1H INDOL 2 YL)BENZYLOXY] 5,6 DIHYDROBENZO[G] 1,3 BENZODIOXOLO[5,6 A]QUINOLIZINIUM BROMIDE; BERBERINE; BERBERINE 5 NITRO 2 PHENYL 1H INDOLE CONJUGATE; INF 55; NORA PUMP INHIBITOR; PROTEIN INHIBITOR; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIAL STRAIN; CONTROLLED STUDY; DRUG CONJUGATION; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; STAPHYLOCOCCUS AUREUS;

ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; BERBERINE; ENTEROCOCCUS FAECALIS; ETHER, ETHYL; INDOLES; INTERCALATING AGENTS; MOLECULAR STRUCTURE; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; STAPHYLOCOCCUS AUREUS;

BACTERIA (MICROORGANISMS); STAPHYLOCOCCUS AUREUS;

EID: 65549100031     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2009.04.028     Document Type: Article

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