Active efflux of antimicrobial agents in wild-type strains of Enterococci

Antimicrobial Agents and Chemotherapy

Volumn 41, Issue 4, 1997, Pages 869-871

  Lynch, Christy ^a   Courvalin, Patrice ^b   Nikaido, Hiroshi ^a,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b INSTITUT PASTEUR   (France)

^c Berkeley   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHLORAMPHENICOL; NORFLOXACIN;

ANTIBIOTIC RESISTANCE; ARTICLE; DRUG ACCUMULATION; DRUG TRANSPORT; ENTEROCOCCUS; ENTEROCOCCUS FAECALIS; NONHUMAN; PRIORITY JOURNAL; STRAIN DIFFERENCE;

EID: 0030893430     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/aac.41.4.869     Document Type: Article

References (16)

1. Baker, C. J., B. J. Webb, and F. F. Barrett. 1976. Antimicrobial susceptibility of group B streptococci isolated from a variety of clinical sources. Antimicrob. Agents Chemother. 10:128-131.
2. Courvalin, P., and C. Carlier. 1986. Transposable multiple antibiotic resistance in Streptococcus pneumoniae. Mol. Gen. Genet. 205:291-297.
3. Fontana, R., R. Cerini, P. Longoni, A. Grossato, and P. Canepari. 1983. Identification of a streptococcal penicillin-binding protein that reacts very slowly with penicillin. J. Bacteriol. 155:1343-1350.
4. Jacob, A. E., and S. J. Hobbs. 1974. Conjugal transfer of plasmid-borne multiple antibiotic resistance in Streptococcus faecalis var. zymogenes. J. Bacteriol. 117:360-372.
5. Li, X.-Z., D. M. Livermore, and H. Nikaido. 1994. Role of efflux pump(s) in intrinsic resistance of Pseudomonas aeruginosa: resistance to tetracycline, chloramphenicol, and norfloxacin. Antimicrob. Agents Chemother. 38:1732-1741.
6. Li, X.-Z., D. Ma, D. M. Livermore, and H. Nikaido. 1994. Role of efflux pump(s) in intrinsic resistance of Pseudomonas aeruginosa: active efflux as a contributing factor to β-lactam resistance. Antimicrob. Agents Chemother. 38:1742-1752.
7. Li, X.-Z., H. Nikaido, and K. Poole. 1995. The role of MexA-MexB-OprM in antibiotic efflux in Pseudomonas aeruginosa. Antimicrob. Agents Chemother. 39:1948-1953.
8. Midgley, M. 1994. Characteristics of an ethidium efflux system in Enterococcus hirae. FEMS Microbiol. Lett. 120:119-124.
9. Murray, B. E. 1990. The life and times of the Enterococcus. Clin. Microbiol. Rev. 3:46-65.
10. Neu, H. C., and K. P. Fu. 1980. In vitro activity of chloramphenicol and thiamphenicol analogs. Antimicrob. Agents Chemother. 18:311-318.
11. Nikaido, H. 1996. Multidrug efflux pumps of gram-negative bacteria. J. Bacteriol. 178:5853-5859.
12. Nikaido, H., and D. G. Thanassi. 1993. Penetration of lipophilic agents with multiple protonation sites into bacterial cells: tetracyclines and fluoroquinolones as examples. Antimicrob. Agents Chemother. 37:1393-1399.
13. Poole, K., K. Krebes, C. McNally, and S. Neshat. 1993. Multiple antibiotic resistance in Pseudomonas aeruginosa: evidence for involvement of an efflux operon. J. Bacteriol. 175:7363-7372.
14. Thanassi, D. G., G. S. B. Suh, and H. Nikaido. 1995. Role of outer membrane barrier in efflux-mediated tetracycline resistance of Escherichia coli. J. Bacteriol. 177:998-1007.
15. Williamson, R., C. Le Bouguénec, L. Gutmann, and T. Horaud. 1985. One or two low affinity penicillin-binding proteins may be responsible for the range of susceptibility of Enterococcus faecium to benzylpenicillin. J. Gen. Microbiol. 131:1933-1940.
16. Zorzi, W., X. Y. Zhou, O. Dardenne, J. Lamotte, D. Raze, J. Pierre, L. Gutmann, and J. Coyette. 1996. Structure of the low-affinity penicillin-binding protein 5 PBP5fm in wild-type and highly penicillin-resistant strains of Enterococcus faecium. J. Bacteriol. 178:4948-4957.