Nephrotoxicity reduction by fixed dose combination of cephalosporins and aminoglycosides in Mus musculus mice

Asian Journal of Biochemistry

Volumn 4, Issue 1, 2009, Pages 13-21

  Dwivedi, V K ^a   Chaudhary, M ^a   Soni, A ^a   Shrivastava, S M ^a  

^a Venus Medicine Research Centre   (India)

Author keywords

Amikacin; Antibiotics; Antioxidant enzymes; Free radical; Nephrotoxicity

Indexed keywords

MUS; MUS MUSCULUS;

EID: 65549090064     PISSN: 18159923     EISSN: None     Source Type: Journal    
DOI: 10.3923/ajb.2009.13.21     Document Type: Article

References (27)

1. Beauchamp, D., G. Thériault, L. Grenier, P. Gourde, S. Perron, Y. Bergeron, L. Fontaine and M.G. Bergeron, 1994. Ceftriaxone protects against tobramycin nephrotoxicity. Antimicrob. Agents Chemother., 38: 750-756.
2. Cantin, A. and D.E. Woods, 1993. Protection by antibiotics against myeloperoxidase-dependant cytotoxicity to lung epithelial cells in vitro. J. Clin. Invest., 91: 38-45.
3. Carlberg, I. and B. Mannervik, 198 5. Glutathione reductase. Method Enzymol., 113: 484-490.
4. Gilbert, D.N., 1995. Aminoglycosides. In: Principles and Practice of Infectious Diseases, Mandell, G.L., J.E. Bennett and R. Dolin (Eds.). 4th Edn., Churchill Livingstone, New York, pp: 279-306.
5. Gilbert, D.N., 2000. Aminoglycosides. In: Principles and Practice of Infectious Diseases, Mandell, G.L., J.E. Bennett and R. Dolin (Eds.). 5th Edn., Churchill Livingstone, New York, pp: 307-336.
6. Kaloyanides, G.J., 1992. Drug-phospholipid interactions: Role in aminoglycoside nephrotoxicity. Ren. Fail., 14: 351-357.
7. Klemens, J.J., R.P. Meech, L.F. Hughes, S. Somani and K.C.M. Campbell, 2003. Antioxidant enzyme levels inversely covary with hearing loss after amikacin treatment. J. Am. Acad. Audiol., 14: 134-142.
8. Lang, H. and C. Liu, 1997. Apoptosis and hair-cell degeneration in the vestibular sensory epithelia of the guinea pig following a gentamicin insults. Hear Res., 111: 177-184.
9. Lapenna, D., L. Cellini, D.S. Gioia, A. Mezzetti and G. Ciofani et al., 1995. Cephalosporins are scavengers of hypochldorous acid. Biochem. Pharmacol., 49: 1249-1254.
10. Laurent, G., M.B. Carlier, B. Rollman, F. Van-Hoof and P. Tulkeris, 1982. Mechanism of aminoglycoside-induced lysosomal phospholipidosis: In vitro and in vivo studies with gentamicin and amikacin. Biochem. Pharmacol., 31: 3861-3870.
11. Luck, 1965. Catalase. In: Method in Enzymatic Analysis, Bergmeyer, H.U. (Ed.). Academic Press, NY., pp: 885-894.
12. Mingeot-Leclereq, M.P. and P.M. Tulkens, 1999. Aminoglycosides: Nephrotoxicity. Antimicrob. Agents Chemother., 43: 1003-1012.
13. Mingeot-Leclercq, M.P., Y. Glupczynski and P.M. Tulkens, 1999. Aminoglycosides: Activity and resistance. Antimicrob. Agents Chemother., 43: 727-737.
14. Misra, H.P. and I. Fridovich, 1972. The role ofsuperoxide anion in the auto-oxidation of epinephrine and a simple assay for superoxide dismutase. J. Biol. Chem., 247: 3170-3175.
15. Ohkawa, H., N. Ohishi and K. Yagi, 1979. Assay of lipid per-oxidation in animal tissue by thio barbutric acid reaction. Anal. Biochem., 95: 351-358.
16. Oliveira, J.F.P., J.P. Cipullo and E.P. Burdmann, 2006. Aminoglycoside nephrotoxicity. Braz. J. Cardiovasc. Surg., 21: 444-452.
17. Ozturk, H.S., M. Kavutcu, M. Kaçmaz, O. Canbolat and I. Durak, 1997. The effects of gentamicin on the activities of glutathione peroxidase and superoxide dismutase enzymes and malondialdehyde levels in heart tissues of guinea pigs. Curr. Med. Res. Opin., 14: 47-52.
18. Pandey, N.R., G. Kaur, M. Chandra, G.G. Sanwal and M.K. Misra, 2000. Enzymatic oxidant antioxidants of human blood platelets in unstable angina and myocardial infarction. Int. J. CaTdiol., 76: 33-38.
19. Rybak, L.P. and S. Somani, 1999. Ototoxicity: Amelioration by protective agents. Annl N. Y. Acad. Sci., 884: 143-151.
20. Selimoglu, E., 2007. Aminoglycoside-Induced Ototoxicity. Curr. Pharm. Design., 13: 119-126.
21. Soejima, A., S. Ishizuka, N. Miyake, K. Fukuoka, M. Suzuki and Y. Kamiya et al., 2000. Simultaneous inhibition of renal phospholipase A (2) and glutathione synthesis by manoalide and DL-buthionine sulfoximine induces acute tubirar dysfunction in rats. Exp. Nephrol., 8: 84-90.
22. Tan, K.H., M. Mulheran, A.J. Knox and A.R. Smyth, 2003. Aminoglycoside prescribing and surveillance in cystic fibrosis. Am. J. Respirat. Crit. Care Med., 167: 819-823.
23. Tumah, H., 2005. Fourth-generation cephalosporins: In vitro activity against nosocomial gram-negative bacilli compared with beta-lactam antibiotics and ciprofloxacin. Chemothrepy, 51: 80-85.
24. Van-Bambeke, F.P.M., R.B. Tulkens and M.P. Mingeot-Leclereq, 1995. Aminoglycoside antibiotics induce aggregation but not fusion of negatively-charged liposomes. Eur. J. Pharmacol., 289: 321-333.
25. Vijayalekshmy, K.S., V. Menon and S. Leelamma, 1992. Role ofantibiotics in lipidperoxidation. Ind. J. Biochem. Biophys., 29: 371-374.
26. Yazaki, T., Y. Yoshiyama, P. Wong, D. Beauchamp and M. Kankc, 2002. Protective effect of fleroxacin aganist the nephrotoxicity of isepamicin in rat. Biol. Pharm. Bull., 25: 516-519.
27. Yazar, E., M. Elmas, V. Altunok, A. Sivrikaya, E. Oztekin and O.B. Yavuz, 2003. Effects of aminoglycoside antibiotics on renal antioxidants, malondialdehyde levels and some serum biochemical parameters. Can. J. Vet. Res., 67: 239-240.