Effects of aminoglycoside antibiotics on renal antioxidants, malondialdehyde levels, and some serum biochemical parameters

Canadian Journal of Veterinary Research

Volumn 67, Issue 3, 2003, Pages 239-240

  Yazar, Enver ^a   Elmas, Muammer ^a   Altunok, Vahdettin ^a   Sivrikaya, Abdullah ^a   Oztekin, Esma ^a   Birdane, Yavuz Osman ^a  

^a SELCUK UNIVERSITY   (Turkey)

Author keywords

[No Author keywords available]

Indexed keywords

AMIKACIN; AMIKOZIT; AMINOGLYCOSIDE ANTIBIOTIC AGENT; ANTIOXIDANT; BILIRUBIN; CREATININE; GENTAMICIN; GENTAVET ENJ; GLUCOSE; GLUTATHIONE PEROXIDASE; KANAMYCIN; KANOVET ENJ; MALONALDEHYDE; POTASSIUM; PROTEIN; SODIUM; STREPTOMYCIN; STREPTOMYCINE SULFATE IE; SUPEROXIDE DISMUTASE; URIC ACID;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BILIRUBIN BLOOD LEVEL; CHEMICAL PARAMETERS; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DOSE RESPONSE; DRUG EFFECT; DRUG INDUCED DISEASE; ENZYME ACTIVITY; GLUCOSE BLOOD LEVEL; MALE; MOUSE; NEPHROTOXICITY; NONHUMAN; OTOTOXICITY; POTASSIUM BLOOD LEVEL; PROTEIN BLOOD LEVEL; URIC ACID BLOOD LEVEL;

AMINOGLYCOSIDES; ANIMALS; ANTI-BACTERIAL AGENTS; ANTIOXIDANTS; BILIRUBIN; BLOOD GLUCOSE; BLOOD PROTEINS; CREATININE; GLUTATHIONE PEROXIDASE; KIDNEY; MALE; MALONDIALDEHYDE; MICE; MICE, INBRED BALB C; POTASSIUM; RANDOM ALLOCATION; SODIUM; SUPEROXIDE DISMUTASE; URIC ACID;

ANIMALIA;

EID: 0041920867     PISSN: 08309000     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (10)

1. Conlon BJ, Aran JM, Erre JP, Bmith DW. Attenuation of aminoglycoside induced cochlear damage with the metabolic antioxidant alpha-lipoic acid. Hear Res 1999;128:40-44.
2. Pedraza-Chaveri J, Maldonado PD, Medina-Campos O, et al. Garlic ameliorates gentamicin nephrotoxicity: relation antioxidant enzymes. Free Radic Biol Med 2000;29:602-611.
3. Diplock AT. Antioxidants and free radicals scavengers. In: Rice-Evans CA, Burdon RH, eds. Free radical damage and its control, Elsevier Science, Amsterdam, Netherlands, 1994.
4. Neilsen F, Mikkelsen BB, Neilsen JB, Andersen HR, Grandjean P. Plasma malondialdehyde as biomarker for oxidative stress: reference interval and effects of life-style factors. Clin Chemist 1997;47:1209-1214.
5. Ellman GL. Tissue sulfhydryl groups. Arch Biochem Biophys 1959;82:70-77.
6. Mihara M, Uchiyama M. Determination of malonaldehyde precursor in tissues by thiobarbituric acid test. Anal Biochem 1978;86:271-278.
7. Vijayalekshmy KS, Menon V, Leelamma S. Role of antibiotics in lipid peroxidation. Ind J Biochem Biophys 1992;29:371-374.
8. Ozturk HS, Kavutcu M, Kaçmaz M, Canbolat O, Durak I. The effects of gentamicin on the activities of glutathione peroxidase and superoxide dismutase enzymes and malondialdehyde levels in heart tissues of guinea pigs. Cur Med Res Opin 1997;14:47-52.
9. Turrens JF. The potential of antioxidant enzymes as pharmacological agents in vivo. Xenobiotica 1991;21:1033-1040.
10. Ramsammy LS, Ling KY, Josepovitz C, Levine R, Kaloyanides GL. Effect of gentamicin on lipid peroxidation in rat renal cortex. Biochem Pharmacol 1985;34:3895-3900.