Antioxidant enzyme levels inversely covary with hearing loss after amikacin treatment

Journal of the American Academy of Audiology

Volumn 14, Issue 3, 2003, Pages 134-143

  Klemens, James J ^a   Meech, Robert P ^a   Hughes, Larry F ^a   Somani, Satu ^a   Campbell, Kathleen C M ^a  

^a SOUTHERN ILLINOIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Amikacin; Aminoglycosides; Antioxidants; Hearing loss; Ototoxicity

Indexed keywords

AMIKACIN; ANTIINFECTIVE AGENT; ANTIOXIDANT; CATALASE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; GLUTATHIONE TRANSFERASE; MALONALDEHYDE; SUPEROXIDE DISMUTASE;

ANALYSIS OF VARIANCE; ANIMAL; ARTICLE; CASE CONTROL STUDY; CHEMICALLY INDUCED DISORDER; COCHLEA; DRUG EFFECT; ENZYMOLOGY; EVOKED BRAIN STEM AUDITORY RESPONSE; GUINEA PIG; HEARING LOSS; LIPID PEROXIDATION; METABOLISM; PATHOPHYSIOLOGY; SUBCUTANEOUS DRUG ADMINISTRATION;

AMIKACIN; ANALYSIS OF VARIANCE; ANIMALS; ANTI-BACTERIAL AGENTS; ANTIOXIDANTS; CASE-CONTROL STUDIES; CATALASE; COCHLEA; EVOKED POTENTIALS, AUDITORY, BRAIN STEM; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; GLUTATHIONE TRANSFERASE; GUINEA PIGS; HEARING LOSS; INJECTIONS, SUBCUTANEOUS; LIPID PEROXIDATION; MALONDIALDEHYDE; SUPEROXIDE DISMUTASE;

EID: 0141922634     PISSN: 10500545     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (50)

1. Aebi H. (1984). Catalase. Methods Enzymol 105:125-126.
2. Aran JM, Chappert C, Dulon, D, Erre JP, Aurousseau C. (1995). Uptake of amikacin by hair cells of the guinea pig cochlea and vestibule and ototoxicity: Comparison with gentamicin. Hear Res 82:179-183.
3. Aust SD, Morehouse LA, Thomas CE. (1985). Role of metals in oxygen radical reactions. J Free Radic Biol Med 1:3-25.
4. Beaubien AR, Desjardins S, Ormsby E, Bayne A, Carrier K, Cauchy MJ, Henri R, Hodgen M, Salley J, St Pierre A. (1990). Delay in hearing loss following drug administration: A consistent feature of amikacin ototoxicity. Acta Otolaryngol (Stockh) 109:345-352.
5. Begg EJ, Barclay ML. (1995). Aminoglycosides-50 years on. Br J Clin Pharmac 39:597-603.
6. Black RE, Lou WK, Weinstein RF, et al. (1976). Ototoxicity of amikacin. Antimicrob Agents Chemother 9:956-961.
7. Bock GR, Yates GK, Miller JJ, Moorjani P. (1983). Effects of N-acetylcysteine on kanamycin ototoxicity in the guinea pig. Hear Res 9(3):255-62.
8. Brummett RE, Fox KE. (1989). Aminoglycoside-induced hearing loss in humans. Antimicrob Agents Chemother 33:797-800.
9. Brummett, RE, Fox, KE, Bendrick, TW, Himes, DL. (1978). "Ototoxicity of Tobramycin, Amikacin, and Sisomicin in the Guinea Pig" Journal of Antimicrobial Chemotherapy 4 (Suppl. A):73-83.
10. Campbell, KCM, Kalkanis, J and Glatz, FR. (2000). Ototoxicity: mechanisms, protective agents, and monitoring. Current Opinion in Otolaryngology & Head and Neck Surgery 8:436-440.
11. Carlberg I, Mannervik B. (1985). Glutathione reductase. Methods Enzymol 113:484-499.
12. Clerici WJ, Hensley K, DiMartino DL, et al.(1996). Direct detection of ototoxicant-induced reactive oxygen species generation in cochlear explants. Hear Res 98:116-124.
13. Crann SA, Huang MY, McLaren JD, et al. (1992). Formation of a toxic metabolite from gentamicin by a hepatic cytosolic fraction. Biochem Pharmacol 43:1835-1839.
14. Crann SA, Schacht J. (1996). Activation of aminoglycoside antibiotics to cytotoxins. Audiol Neurootol 1(2):80-85.
15. Edson, RS, Terrell, CL. (1999). The Aminoglycosides. Mayo Clin Proc 74:519-528
16. Fausti SA, Henry JA, Helt WJ, Phillips DS, Frey RH, Noffsinger D, Larson YD, Fowler CG. (1999)An individualized, sensitive frequency range for early detection of Ototoxicity. Ear Hear; 20(6):497-505.
17. Flohe L, Gunzler WA.(1984). Glutathione peroxidase. Methods Enzymol 105:115-121.
18. Forge A, Schacht J. (2000). Aminoglycoside antibiotics. Audiol Neurootol 5(1):3-22.
19. Govaerts PJ, Claes J, van de Heyning PH, Jorens PG, Marquet J, De Broe ME. (1990). Aminoglycoside-induced ototoxicity. Toxicol Lett 52(3):227-51.
20. Habig WH, Pabst MJ, Jakoby WB. (1974). Glutathione S-transferases. The first step in mercapturic acid formation. J Biol Chem 249:7130-7139.
21. Hawkins JE, Johnsson L (1981). "Histopathology of Cochlear and Vestibular Ototoxicity in Laboratory Animals" In: Lerner, SA, Matz, GJ and Hawkins, JE, ed. Aminoglycoside Ototoxicity. Boston: Little Brown and Company, 175-196.
22. Hayashida T. (1989).An immunohistochemical method for the study of aminoglycoside ototoxicity in the guinea pig cochlea using decalcified frozen sections. Arch Otorhinolaryngol 246:161-164.
23. Hiel H, Schamel A, Erre JP, Hayashida T, Dulon D, Aran JM. (1992). Cellular and subcellular localization of tritiated gentamicin in the guinea pig cochlea following combined treatment with ethacrynic acid. Hear Res 57(2):157-165.
24. Hirose, K, Hockenberry, DN, Rubel, EW. (1997). Reactive oxygen species in chick hair cells after gentamicin exposure in vitro. Hear Res 104:1-14.
25. Huang MY, Schacht J. (1990). Formation of a cytotoxic metabolite from gentamicin by liver. Biochem Pharmacol 40:R11-R14.
26. Huizing EH, deGroot JCMJ. (1987). Human cochlear pathology in aminoglycoside ototoxicity-a review. Acta Otolaryngol Suppl (Stockh) 436:117-125.
27. Lane, AZ, Wright GE, Blair DC. (1977). Ototoxicity and nephrotoxicity of amikacin: An overview of phase II and phase III experience in the United States. Am J Med 62:911-918.
28. Lautermann J, McLaren J, Schacht J. (1995). Glutathione protection against gentamicin ototoxicity depends on nutritional status. Hearing Research 86:15-24.
29. Matz GJ. (1993). Aminoglycoside cochlear ototoxicity. Otolaryngol Clin North Am 26:705-712.
30. McCracken GH. (1986). Aminoglycoside toxicity in infants and children. Am J Med 80 Suppl:172-178.
31. Misra HP, Fridovich 1. (1972).The role of superoxide anion in the autooxidation of epinephrine and a simple assay for SOD. J Biol Chem 247:3170-3175.
32. Nadol, J. (1981). "Histopathology of Human Aminoglycoside Ototoxicity." In: Lerner, SA, Matz, GJ, and Hawkins, JE, eds. Boston: Little Brown and Company, 409-434.
33. Nishida I, Takumida M. (1996).Attenuation of aminoglycoside ototoxicity by glutathione. ORL J Otorhinolaryngol Relat Spec 58:68-73.
34. Ohkawa H, Ohishi N, Yagi K. (1979). Assay for lipid peroxides in animals and tissues by thiobarbituric acid reactions. Anal Biochem 95:351-358.
35. Prazma, J, Garrison, HG, Williford, SK, Ferguson, SD, Fischer, J, Drake, A, & Klingler, I.E. (1983). "Alteration of Aminoglycoside Antibiotic Ototoxicity: Effect of Semistarvation." Ann Otol Rhinol Laryngol 92:178-182.
36. Priuska EM, Schacht J. (1995) Formation of free radicals by gentamicin and iron and evidence for an iron/gentamicin complex. Biochem Pharmacol 50(11):1749-52.
37. Priuska EM, Schacht J. (1997). Mechanism and prevention of aminoglycoside ototoxicity: Outer hair cells as targets and tools. Ear Nose Throat J 76(3):164-166.
38. Read SM, Northcole DH. (1981). Minimization of variation in the response to different proteins of the Coomassie blue G dye binding assay for protein. Anal Biochem 116:53-64.
39. Schacht J, Weiner N. (1986). Aminoglycoside-induced hearing loss: A molecular hypothesis. ORL J Otorhinolaryngol Relat Spec 48:116-123.
40. Schuknecht, H.F. (1957).Ablation therapy in the management of Meniere's disease. Acta Otolaryngol Suppl (Stockh) 132:1-42.
41. Sha S, Schacht J. (1999). Stimulation of free radical formation by aminoglycoside antibiotics. Hear Res 128:112-118.
42. Sha S, Schacht J. (2000). Antioxidants attenuate gentamicin-induced free radical formation in vitro and ototoxicity in vivo: D-methionine is a potential protectant. Hear Res 142:34-40.
43. Sha S, Taylor R, Forge A, Schacht J. (2001). Differential vulnerability of basal and apical hair cells is based on intrinsic susceptibility to free radicals. Hear Res 155:1-8.
44. Shacht J. (1993). Biochemical basis of aminoglycoside ototoxicity. Otolaryngol Clin North Am 26:845-856.
45. Sone M, Schachern PA, Paparella MM. (1998). Loss of spiral ganglion cells as primary manifestation of aminoglycoside Ototoxicity. Hear Res 115(1-2):217-23.
46. Song BB, Schacht J. (1996). Variable efficacy of radical scavengers and iron chelators to attenuate gentamicin ototoxicity in guinea pig in vivo. Hear Res 94:87-93.
47. Song BB, Anderson DJ, Schacht J. (1997). Protection from Gentamicin Ototoxicityby iron chelators in guinea pig in vivo. J Pharmacol Exp Ther 282:369-377.
48. Stebbins WC, McGinn CS, Feitosa AG, Moody DB, Prosen CA, Serafin JV (1981) "Animal Models in the Study of Ototoxic Hearing Loss" In: Lerner SA, Matz GJ, and Hawkins JE, eds. Aminoglycoside Ototoxicity, Boston: Little Brown and Company, 5-26.
49. Tange RA, Conijn EAJG, van Zeijl LGPM, et al. (1982). Pattern of gentamicin-induced cochlear degeneration in the guinea pig. Arch Otolaryngol Head Neck Surg 236:173-184.
50. Weiner ND, Schacht J (1981). "Biochemical Model of Aminoglycoside-Induced Hearing Loss" In: Lerner, SA Matz, GJ and Hawkins, JE, eds. Aminoglycoside Ototoxicity Boston: Little Brown and Company, 113-123.