3D cryo-imaging: A very high-resolution view of the whole mouse

Anatomical Record

Volumn 292, Issue 3, 2009, Pages 342-351

  Roy, Debashish ^a   Steyer, Grant J ^a   Gargesha, Madhusudhana ^a   Stone, Meredith E ^a   Wilson, David L ^a,b  

^a Case Western Reserve University   (United States)

^b UNIVERSITY HOSPITALS OF CLEVELAND   (United States)

Author keywords

Block face imaging; Brightfield microscopy; Cryosection; Fluorescence microscopy; Small animal imaging

Indexed keywords

ACTIN; ENHANCED GREEN FLUORESCENT PROTEIN; GAMMA ACTIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTOMATION; COMPUTER PROGRAM; CONTRAST ENHANCEMENT; EMBRYO; FLUORESCENCE ANALYSIS; FLUORESCENCE MICROSCOPY; GASTROINTESTINAL TRACT; HEART BLOOD VESSEL; HISTOLOGY; IMAGE DISPLAY; IMAGE QUALITY; IMAGING SYSTEM; INTESTINE VILLUS; MICROTOME; MOLECULAR IMAGING; MUSCLE TISSUE; NONHUMAN; OPTIC NERVE; PRIORITY JOURNAL; PROMOTER REGION; ROBOTICS; SMOOTH MUSCLE FIBER; THREE DIMENSIONAL IMAGING; UROGENITAL SYSTEM; VISUAL SYSTEM;

ACTINS; ANIMALS; AUTOMATION; DIAGNOSTIC IMAGING; FLUORESCENCE; GREEN FLUORESCENT PROTEINS; IMAGE PROCESSING, COMPUTER-ASSISTED; IMAGING, THREE-DIMENSIONAL; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MUSCLE, SMOOTH; PROMOTER REGIONS, GENETIC; WHOLE BODY IMAGING;

ANIMALIA;

EID: 65549088148     PISSN: 19328486     EISSN: 19328494     Source Type: Journal    
DOI: 10.1002/ar.20849     Document Type: Article

References (28)

1. Abbas B, Hayes TL, Wilson DJ, Carr KE. 1989. Internal structure of the intestinal villus: morphological and morphometric observations at different levels of the mouse villus. J Anat 162:263-273.
2. Ackerman MJ. 1991. The visible human project. J Biocommun 18:14.
3. Annese J, Sforza DM, Dubach M, Bowden D, Toga AW. 2006. Post-mortem high-resolution 3-dimensional imaging of the primate brain: blockface imaging of perfusion stained tissue. Neuroimage 30:61-69.
4. Bamforth SD, Braganca J, Eloranta JJ, Murdoch JN, Marques FI, Kranc KR, Farza H, Henderson DJ, Hurst HC, Bhattacharya S. 2001. Cardiac malformations, adrenal agenesis, neural crest defects and exencephaly in mice lacking Cited2, a new Tfap2 co-activator. Nat Genet 29:469-474.
5. Bedell MA, Jenkins NA, Copeland NG. 1997. Mouse models of human disease. I. Techniques and resources for genetic analysis in mice. Genes Dev 11:1-10.
6. Boas DA, Brooks DH, Miller EL, DiMarzio CA, Kilmer M, Gaudette RJ, Quan Z. 2001. Imaging the body with diffuse optical tomography. IEEE Signal Process Mag 18:57-75.
7. Breen MS, Lazebnik RS, Fitzmaurice M, Nour SG, Lewin JS, Wilson DL. 2004. Radiofrequency thermal ablation: correlation of hyperacute MR lesion images with tissue response. J Magn Reson Imaging 20:475-486.
8. Brown SD, Hancock JM, Gates H. 2006. Understanding mammalian genetic systems: the challenge of phenotyping in the mouse. PLoS Genet 2:e118.
9. Cannestra AF, Santori EM, Holmes CJ, Toga AW. 1997. A three-dimensional multimodality brain map of the nemestrina monkey. Brain Res Bull 43:141-148.
10. Dogdas B, Stout D, Chatziioannou AF, Leahy RM. 2007. Digimouse: a 3D whole body mouse atlas from CT and cryosection data. Phys Med Biol 52:577-587.
11. Ebert DS, Ebert DS, Morris CJ, Rheingans P, Yoo TS. 2002. Designing effective transfer functions for volume rendering from photographic volumes designing effective transfer functions for volume rendering from photographic volumes. IEEE Trans Visualization Comput Graphics 8:183-197.
12. Griffini P, Smorenburg SM, Verbeek FJ, van Noorden CJ. 1997. Three-dimensional reconstruction of colon carcinoma metastases in liver. J Microsc 187(Pt 1):12-21.
13. Kaufman MH, Brune RM, Baldock RA, Bard JB, Davidson D. 1997. Computer-aided 3-D reconstruction of serially sectioned mouse embryos: its use in integrating anatomical organization. Int J Dev Biol 41:223-233.
14. Kenzie-Graham A, Lee EF, Dinov ID, Bota M, Shattuck DW, Ruffins S, Yuan H, Konstantinidis F, Pitiot A, Ding Y, Hu G, Jacobs RE, Toga AW. 2004. A multimodal, multidimensional atlas of the C57BL/6J mouse brain. J Anat 204:93-102.
15. Lazebnik RS, Weinberg BD, Breen MS, Lewin JS, Wilson DL. 2002. Three-dimensional model of lesion geometry for evaluation of MR-guided thermal ablation therapy. Acad Radiol 9:1128-1138.
16. MacLaren DC, Gambhir SS, Satyamurthy N, Barrio JR, Sharfstein S, Toyokuni T, Wu L, Berk AJ, Cherry SR, Phelps ME, Herschman HR. 1999. Repetitive, non-invasive imaging of the dopamine D2 receptor as a reporter gene in living animals. Gene Ther 6:785-791.
17. Manconi F, Markham R, Cox G, Kable E, Fraser IS. 2001. Computer-generated, three-dimensional reconstruction of histological parallel serial sections displaying microvascular and glandular structures in human endometrium. Micron 32:449-453.
18. Massoud TF, Gambhir SS. 2003. Molecular imaging in living subjects: seeing fundamental biological processes in a new light. Genes Dev 17:545-580.
19. Park JS, Chung MS, Hwang SB, Lee YS, Har DH, Park HS. 2005. Visible Korean human: improved serially sectioned images of the entire body. IEEE Trans Med Imaging 24:352-360.
20. Rosenthal J, Mangal V, Walker D, Bennett M, Mohun TJ, Lo CW. 2004. Rapid high resolution three dimensional reconstruction of embryos with episcopic fluorescence image capture. Birth Defects Res C Embryo Today 72:213-223.
21. Roy D, Breen M, Salvado O, Heinzel M, McKinley E, Wilson D. 2006. Imaging system for creating 3D block-face cryo-images of whole mice. In: Manduca A, Amini A, editors. Medical imaging 2006: physiology, function, and structure from medical images. p 6143[1], 61431E-8; SPIE, San Diego, CA, USA.
22. Salvado O, Roy D, Heinzel M, McKinley E, Wilson D. 2006. 3D cryo-section/ imaging of blood vessel lesions for validation of MRI data. In: Flynn MJ, Hsieh J, editors. Medical imaging 2006: physics of medical imaging. p 6142[1], 614214-10; SPIE, San Diego, CA, USA.
23. Sharpe J, Ahlgren U, Perry P, Hill B, Ross A, Hecksher-Sorensen J, Baldock R, Davidson D. 2002. Optical projection tomography as a tool for 3D microscopy and gene expression studies. Science 296:541-545.
24. Spitzer VM, Whitlock DG. 1998. The visible human dataset: the anatomical platform for human simulation. Anat Rec 253:49-57.
25. Szucsik JC, Lewis AG, Marmer DJ, Lessard JL. 2004. Urogenital tract expression of enhanced green fluorescent protein in transgenic mice driven by a smooth muscle gamma-actin promoter. J Urol 171:944-949.
26. Ware RW. 1975. Three-dimensional reconstruction from serial sections. Int Rev Cytol 40:325-440.
27. Weninger WJ, Geyer SH, Mohun TJ, Rasskin-Gutman D, Matsui T, Ribeiro I, Costa LF, Izpisua-Belmonte JC, Muller GB. 2006. High-resolution episcopic microscopy: a rapid technique for high detailed 3D analysis of gene activity in the context of tissue architecture and morphology. Anat Embryol (Berl) 211:213-221.
28. Zhang SX, Heng PA, Liu ZJ, Tan LW, Qiu MG, Li QY, Liao RX, Li K, Cui GY, Guo YL, Yang XP, Liu GJ, Shan JL, Liu JJ, Zhang WG, Chen XH, Chen JH, Wang J, Chen W, Lu M, You J, Pang XL, Xiao H, Xie YM. 2003. Creation of the Chinese visible human data set. Anat Rec B New Anat 275:190-195.