Estrogen activities and the cellular effects of natural progesterone from wild yam extract in MCF-7 human breast cancer cells

American Journal of Chinese Medicine

Volumn 37, Issue 1, 2009, Pages 159-167

  Park, Mi Kyung ^a   Kwon, Hyeok Yi ^a   Ahn, Woong Shick ^b   Bae, Sumi ^b   Rhyu, Mee Ra ^c   Lee, Young Joo ^a  

^a Sejong University   (South Korea)

^b The Catholic University of Korea College of Medicine   (South Korea)

^c Korea Food Research Institute   (South Korea)

Author keywords

Menopause; Phytoestrogen; Wild yam

Indexed keywords

ESTRADIOL; ESTROGEN; ESTROGEN RECEPTOR ALPHA; MESSENGER RNA; PLANT EXTRACT; PROGESTERONE; PROGESTERONE RECEPTOR; PROTEIN PS2; UNCLASSIFIED DRUG; WILD YAM EXTRACT;

ARTICLE; BREAST ADENOCARCINOMA; CANCER CELL CULTURE; CARCINOMA CELL; CELL GROWTH; CELL PROLIFERATION; CELL STRAIN MCF 7; CONTROLLED STUDY; DOWN REGULATION; DRUG ACTIVITY; HORMONE ACTION; HUMAN; HUMAN CELL; RECEPTOR INTRINSIC ACTIVITY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION; WESTERN BLOTTING;

EID: 65449183369     PISSN: 0192415X     EISSN: None     Source Type: Journal    
DOI: 10.1142/S0192415X09006746     Document Type: Article

References (29)

1. Adlercreutz, H., H. Markkanen and S. Watanabe. Plasma concentrations of phyto-oestrogens in Japanese men. Lancet 342: 1209-1210, 1993.
2. Aradhana, A.R. Rao, and R.K. Kale. Diosgenin - A growth stimulator of mammary gland of ovariectomized mouse. Indian J. Exp. Biol. 30: 367-370, 1992.
3. Barber, R., M. Hickey and M. Kwik. Therapy for menopausal symptoms during and after treatment for breast cancer. Drug Safety 28: 1085-1100, 2005.
4. Barnes, S. and T.G. Peterson. Biochemical targets of the isoflavone genistein in tumor cell lines. Proc. Soc. Exp. Biol. Med. 208: 103-108, 1995.
5. Carroll, D.G. Nonhormonal therapies for hot flashes in menopause. Am. Fam. Physician 73: 457-464, 2006.
6. Chen, H.Y., W.C. Cho, S.C. Sze and Y. Tong. Treatment of menopausal symptoms with Er-xian decoction: A systematic review. Am. J. Chin. Med. 36: 233-244, 2008.
7. Dalton, K. The Premenstrual Syndrome and Progesterone Therapy, England, London: William Heinemann. 1984.
8. Dennerstein, L., E.C. Dudley, J.L. Hopper, J.R. Guthrie and H.G. Burger. A prospective population-based study of menopausal symptoms. Obstet. Gynecol. 96: 351-358, 2000.
9. Gehm, B.D., J.M. McAndrews, P.Y. Chien and J.L. Jameson. Resveratrol, a polyphenolic compound found in grapes and wine, is an agonist for the estrogen receptor. Proc. Natl. Acad. Sci. USA 94: 14138-14143, 1997.
10. Glazier, M.G. and M.A. Bowman. A review of the evidence for the use of phytoestrogens as a replacement for traditional estrogen replacement therapy. Arch. Intern. Med. 161: 1161-1172, 2001.
11. Haimov-Kochman, R. and D. Hochner-Celnikier. Hot flashes revisited: pharmacological and herbal options for hot flashes management. What does the evidence tell us? Acta Obstet. Gynecol. Scand. 84: 972-979, 2005.
12. Hargrove, J.T., W.S. Maxson, A.C. Wentz and L.S. Burnett. Menopausal hormone replacement therapy with continuous daily oral micronized estradiol and progesterone. Obstet. Gynecol. 73: 606-612, 1989.
13. Higdon, K., A. Scott, M. Tucci, H. Benghuzzi, A. Tsao, A. Puckett, Z. Cason and J. Hughes. The use of estrogen, DHEA, and diosgenin in a sustained delivery setting as a novel treatment approach for osteoporosis in the ovariectomized adult rat model. Biomed. Sci. Instrum. 37: 281-286, 2001.
14. Hulley, S., D. Grady, T. Bush, C. Furberg, D. Herrington, B. Riggs and E. Vittinghoff. Randomized trial of estrogen plus progestin for secondary prevention of coronary heart disease in postmenopausal women. Heart and estrogen/progestin replacement study (HERS) research group. J. Am. Med. Assoc. 280: 605-613, 1998.
15. Komesaroff, P.A., C.V.S. Black, V. Cable and K. Sudbir. Effects of wild yam extract on menopausal symptoms, lipids and sex hormones in healthy menopausal women. Climacteric. 4: 144-150, 2001.
16. Lee, J.R. What Your Doctor May Not Tell You About Menopause. New York, NY:WArner Books. 1996.
17. Liu, J., J.E. Burdette, H. Xu, C. Gu, R.B. van Breemen, K.P. Bhat, N. Booth, A.I. Constantinou, J.M. Pezzuto, H.H. Fong, N.R. Farnsworth and J.L. Bolton. Evaluation of estrogenic activity of plant extracts for the potential treatment of menopausal symptoms. J. Agric. Food. Chem. 49: 2472-2479, 2001.
18. Maxson, W.S. The use of progesterone in the treatment of PMS. Clin. Obstet. Gynecol. 30: 465-477, 1987.
19. Mercier, G.,N. Turque and M. Schumacher. Rapid effects of triiodothyronine on immediate-early gene expression in Schwann cells. Glia 35: 81-89, 2001.
20. Price, K.R. and G.R. Fenwick. Naturally occurring estrogens in foods - Areview. Food Addit. Contam. 2: 73-106, 1985.
21. Prior, J.C. Progesterone as a bone-trophic hormone. Endocr. Rev. 11: 386-398, 1990.
22. Ren, L., M.A. Marquardt and J.J. Leeh. Estrogenic effects of nonylphenol on pS2, ER and MUCI gene expression in human breast cancer cell-MCF-7. Chem. Biol. Interact. 104: 55-64, 1997.
23. Setchell, K.D. Phytoestrogens: The biochemistry, physiology, and implications for human health of soy isoflavones. Am. J. Clin. Nutr. 68: 1333S-1346S, 1998.
24. The writing group for the PEPI trial. Effects of estrogen or estrogen/ progestin regimens on heart disease risk factors in postmenopausal women. JAMA 273: 199-208, 1995.
25. Thompson, L.U., P. Robb and M. Serraino. Mammalian lignan production from various foods. Nutr. Cancer 16: 43-52, 1991.
26. Vercellini, P., O.D. Giorgi, S. Oldani, I. Cortesi, S. Panazza and P.G. Crosignani. Depot medroxyprogesterone acetate versus an oral contraceptive combined with very-low-dose danazol for longed with endometriosis. Am. J. Obstet. Gynecol. 175: 396-401, 1996.
27. Woo, J., E. Lau, S.C. Ho, F. Cheng, C. Chan, A.S. Chan, C.J. Haines, T.Y. Chan, M. Li. and A. Sham. Comparison of Pueraria labata with hormone replacement therapy in treating the adverse health consequences of menopause. Menopause 10: 352-361, 2003.
28. Wu, W.H., L. Liu, C. Chung, H. Jou and Y. Wang. Estrogenic effect of yam ingestion in healthy postmenopausal women. J. Am. Coll. Nutr. 24: 235-243, 2005.
29. Zava, D.T., C.M. Dollbaum and M. Blen, Estrogen and progestin bioactivity of foods, herbs and spices. Proc. Soc. Exp. Biol. Med. 217: 369-378, 1998.