Modulation of TLR signaling by multiple MyD88-interacting partners including leucine-rich repeat Fli-I-interacting proteins

Journal of Immunology

Volumn 182, Issue 6, 2009, Pages 3450-3460

  Dai, Penggao ^a   Jeong, Sun Yong ^a   Yu, Yanbao ^a,b,c   Leng, Taohua ^c   Wu, Weidong ^a   Xie, Ling ^a   Chen, Xian ^a,c  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

^c FUDAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LEUCINE RICH REPEAT FLI I PROTEIN; LIPOPOLYSACCHARIDE; MYELOID DIFFERENTIATION FACTOR 88; PROTEIN; TOLL LIKE RECEPTOR 4; UNCLASSIFIED DRUG; ACTIN BINDING PROTEIN; CARRIER PROTEIN; CELL RECEPTOR; CYTOSKELETON PROTEIN; FLII PROTEIN, HUMAN; FLIIH PROTEIN, MOUSE; LRRFIP1 PROTEIN, HUMAN; LRRFIP2 PROTEIN, HUMAN; MYD88 PROTEIN, HUMAN; RNA BINDING PROTEIN; TLR4 PROTEIN, HUMAN;

ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; EMBRYO; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IN VIVO STUDY; INFLAMMATION; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PROTEIN INTERACTION; PROTEOMICS; SIGNAL TRANSDUCTION; ANIMAL; BINDING COMPETITION; C3H MOUSE; CELL LINE; COMPARATIVE STUDY; DRUG ANTAGONISM; DRUG POTENTIATION; IMMUNOLOGY; METABOLISM; PHYSIOLOGY; TUMOR CELL LINE;

ANIMALS; BINDING, COMPETITIVE; CARRIER PROTEINS; CELL LINE; CELL LINE, TUMOR; CYTOSKELETAL PROTEINS; HUMANS; MACROPHAGES; MICE; MICE, INBRED C3H; MICROFILAMENT PROTEINS; MYELOID DIFFERENTIATION FACTOR 88; NF-KAPPA B; PROTEIN BINDING; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RNA-BINDING PROTEINS; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4;

EID: 65449153955     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0802260     Document Type: Article

References (35)

1. Liew, F. Y., D. Xu, E. K. Brint, and L. A. O'Neill. 2005. Negative regulation of Toll-like receptor-mediated immune responses. Nat. Rev. Immunol. 5: 446-458.
2. Dunne, A., and L. A. O'Neill. 2003. The interleukin-1 receptor/Toll-like receptor superfamily: signal transduction during inflammation and host defense. Sci. STKE 2003: re3.
3. Janeway, C. A., Jr., and R. Medzhitov. 2002. Innate immune recognition. Annu. Rev. Immunol. 20: 197-216.
4. Akira, S., and K. Takeda. 2004. Toll-like receptor signalling. Nat. Rev. Immunol. 4: 499-511.
5. Medzhitov, R. 2001. Toll-like receptors and innate immunity. Nat. Rev. Immunol. 1: 135-145.
6. Takeda, K., T. Kaisho, and S. Akira. 2003. Toll-like receptors. Annu. Rev. Immunol. 21: 335-376.
7. O'Neill, L. A. 2003. The role of MyD88-like adapters in Toll-like receptor signal transduction. Biochem. Soc. Trans. 31: 643-647.
8. Blagoev, B., I. Kratchmarova, S. E. Ong, M. Nielsen, L. J. Foster, and M. Mann. 2003. A proteomics strategy to elucidate functional protein-protein interactions applied to EGF signaling. Nat. Biotechnol. 21: 315-318.
9. Bouwmeester, T., A. Bauch, H. Ruffner, P. O. Angrand, G. Bergamini, K. Croughton, C. Cruciat, D. Eberhard, J. Gagneur, S. Ghidelli, et al. 2004. A physical and functional map of the human TNF-α/NF-κB signal transduction pathway. Nat. Cell. Biol. 6: 97-105.
10. Wang, T., S. Gu, T. Ronni, Y. C. Du, and X. Chen. 2005. In vivo dual-tagging proteomic approach in studying signaling pathways in immune response. J. Proteome Res. 4: 941-949.
11. Chen, X., L. M. Smith, and E. M. Bradbury. 2000. Site-specific mass tagging with stable isotopes in proteins for accurate and efficient protein identification. Anal. Chem. 72: 1134-1143.
12. Ong, S. E., B. Blagoev, I. Kratchmarova, D. B. Kristensen, H. Steen, A. Pandey, and M. Mann. 2002. Stable isotope labeling by amino acids in cell culture, SILAC, as a simple and accurate approach to expression proteomics. Mol. Cell. Proteomics 1: 376-386.
13. Wang, T., T. H. Chuang, T. Ronni, S. Gu, Y. C. Du, H. Cai, H. Q. Sun, H. L. Yin, and X. Chen. 2006. Flightless I homolog negatively modulates the TLR pathway. J. Immunol. 176: 1355-1362.
14. Fong, K. S., and H. G. de Couet. 1999. Novel proteins interacting with the leucine-rich repeat domain of human flightless-I identified by the yeast two-hybrid system. Genomics 58: 146-157.
15. Lee, Y. H., and M. R. Stallcup. 2006. Interplay of Fli-I and FLAP1 for regulation of β-catenin dependent transcription. Nucleic Acids Res. 34: 5052-5059.
16. Liu, J., A. G. Bang, C. Kintner, A. P. Orth, S. K. Chanda, S. Ding, and P. G. Schultz. 2005. Identification of the Wnt signaling activator leucine-rich repeat in Flightless interaction protein 2 by a genome-wide functional analysis. Proc. Natl. Acad. Sci. USA 102: 1927-1932.
17. Suriano, A. R., A. N. Sanford, N. Kim, M. Oh, S. Kennedy, M. J. Henderson, K. Dietzmann, and K. E. Sullivan. 2005. GCF2/LRRFIP1 represses tumor necrosis factor alpha expression. Mol. Cell. Biol. 25: 9073-9081.
18. Zieske, L. R. 2006. A perspective on the use of iTRAQ reagent technology for protein complex and profiling studies. J. Exp. Bot. 57: 1501-1508.
19. Soukup, J. M., and S. Becker. 2003. Role of monocytes and eosinophils in human respiratory syncytial virus infection in vitro. Clin. Immunol. 107: 178-185.
20. Gil, J., and M. Esteban. 2000. The interferon-induced protein kinase (PKR), triggers apoptosis through FADD-mediated activation of caspase 8 in a manner independent of Fas and TNF-α receptors. Oncogene 19: 3665-3674.
21. Dai, P., W. C. Xiong, and L. Mei. 2006. Erbin inhibits RAF activation by disrupting the sur-8-Ras-Raf complex. J. Biol. Chem. 281: 927-933.
22. McDonald, C., F. F. Chen, V. Ollendorff, Y. Ogura, S. Marchetto, P. Lecine, J. P. Borg, and G. Nunez. 2005. A role for Erbin in the regulation of Nod2-dependent NF-κB signaling. J. Biol. Chem. 280: 40301-40309.
23. Beutler, B. 2000. Tlr4: central component of the sole mammalian LPS sensor. Curr. Opin. Immunol. 12: 20-26.
24. Qureshi, S. T., L. Lariviere, G. Leveque, S. Clermont, K. J. Moore, P. Gros, and D. Malo. 1999. Endotoxin-tolerant mice have mutations in Toll-like receptor 4 (Tlr4). J. Exp. Med. 189:615-625.
25. Poltorak, A., X. He, I. Smirnova, M. Y. Liu, C. Van Huffel, X. Du, D. Birdwell, E. Alejos, M. Silva, C. Galanos, et al. 1998. Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene. Science 282: 2085-2088.
26. Lehner, M. D., S. Morath, K. S. Michelsen, R. R. Schumann, and T. Hartung. 2001. Induction of cross-tolerance by lipopolysaccharide and highly purified lipoteichoic acid via different Toll-like receptors independent of paracrine mediators. J. Immunol. 166: 5161-5167.
27. Hoshino, K., O. Takeuchi, T. Kawai, H. Sanjo, T. Ogawa, Y. Takeda, K. Takeda, and S. Akira. 1999. Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: evidence for TLR4 as the Lps gene product. J. Immunol. 162:3749-3752.
28. Verma, I. M., J. K. Stevenson, E. M. Schwarz, D. Van Antwerp, and S. Miyamoto. 1995. Rel/NF-κB/IκB family: intimate tales of association and dissociation. Genes Dev. 9: 2723-2735.
29. Baldwin, A. S., Jr. 1996. The NF-κB and IκB proteins: new discoveries and insights. Annu. Rev. Immunol. 14: 649-683.
30. Yamamoto, Y., and R. B. Gaynor. 2004. IκB kinases: key regulators of the NF-κB pathway. Trends Biochem. Sci. 29: 72-79.
31. Viatour, P., M. P. Merville, V. Bours, and A. Chariot. 2005. Phosphorylation of NF-κB and IκB proteins: implications in cancer and inflammation. Trends Biochem. Sci. 30: 43-52.
32. Ghosh, S., and M. Karin. 2002. Missing pieces in the NF-κB puzzle. Cell 109(Suppl.): S81-S96.
33. Archer, S. K., C. A. Behm, C. Claudianos, and H. D. Campbell. 2004. The flightless I protein and the gelsolin family in nuclear hormone receptor-mediated signalling. Biochem. Soc. Trans. 32: 940-942.
34. Diehl, G. E., H. H. Yue, K. Hsieh, A. A. Kuang, M. Ho, L. A. Morici, L. L. Lenz, D. Cado, L. W. Riley, and A. Winoto. 2004. TRAIL-R as a negative regulator of innate immune cell responses. Immunity 21: 877-889.
35. Boone, D. L., E. E. Turer, E. G. Lee, R. C. Ahmad, M. T. Wheeler, C. Tsui, P. Hurley, M. Chien, S. Chai, O. Hitotsumatsu, et al. 2004. The ubiquitin-modifying enzyme A20 is required for termination of Toll-like receptor responses. Nat. Immunol. 5: 1052-1060.