Differential recognition of surface proteins in Streptococcus pyogenes by two sortase gene homologs

Journal of Bacteriology

Volumn 184, Issue 8, 2002, Pages 2181-2191

  Barnett, Timothy C ^a   Scott, June R ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL DNA; BACTERIAL ENZYME; CELL SURFACE PROTEIN; PROTEIN F; PROTEIN GRAB; PROTEIN M6; PROTEIN SCPA; PROTEIN T6; SORTASE; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL GENE; BACTERIAL STRAIN; BACTERIUM MUTANT; CONTROLLED STUDY; DNA HYBRIDIZATION; GENE FUNCTION; GENE INACTIVATION; GENE MUTATION; GENOME; MOLECULAR RECOGNITION; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PHENOTYPE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN LOCALIZATION; PROTEIN MOTIF; SEQUENCE HOMOLOGY; SITE DIRECTED MUTAGENESIS; STAPHYLOCOCCUS AUREUS; STRAIN DIFFERENCE; STREPTOCOCCUS GROUP C; STREPTOCOCCUS GROUP G; STREPTOCOCCUS PYOGENES; WILD TYPE;

AMINO ACID SEQUENCE; AMINOACYLTRANSFERASES; BACTERIAL PROTEINS; CELL WALL; CYSTEINE ENDOPEPTIDASES; DNA TRANSPOSABLE ELEMENTS; MOLECULAR SEQUENCE DATA; MUTATION; STREPTOCOCCUS PYOGENES;

BACTERIA (MICROORGANISMS); INSERTION SEQUENCES; POSIBACTERIA; PROKARYOTA; STAPHYLOCOCCUS; STAPHYLOCOCCUS AUREUS; STREPTOCOCCUS PYOGENES; STREPTOCOCCUS SP. 'GROUP A'; STREPTOCOCCUS SP. 'GROUP C'; STREPTOCOCCUS SP. 'GROUP G'; TRANSPOSONS;

EID: 0036207211     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/JB.184.8.2181-2191.2002     Document Type: Article

References (70)

1. Bacterial determinants of persistent throat colonization and the associated immune response in a primate model of human group A streptococcal pharyngeal infection
2. Molecular analysis of the role of the group A streptococcal cysteine protease, hyaluronic acid capsule, and M protein in a murine model of human invasive soft-tissue infection
3. Genomic localization of a T serotype locus to a recombinatorial zone encoding for extracellular matrix-binding proteins in Streptococcus pyogenes
4. Generation and surface localization of intact M protein in Streptococcus pyogenes are dependent on sagA
5. Inactivation of the srtA gene in Streptococcus gordonii inhibits cell wall anchoring of surface proteins and decreases in vitro and in vivo adhesion
6. Environmental regulation of virulence in group A streptococci: Transcription of the gene encoding M protein is stimulated by carbon dioxide
7. Complete nucleotide sequence of the streptococcal C5a peptidase gene of Streptococcus pyogenes
8. Streptococcal C5a peptidase is a highly specific endopeptidase
9. Studies of the receptor for phage A25 in group A streptococci: The role of peptidoglycan in reversible adsorption
10. Group G streptococcal M protein exhibits structural features analogous to those of class I M protein of group A streptococci
11. Sortase, a universal target for therapeutic agents against gram-positive bacteria?
12. Serum opacity factor is a major fibronectin-binding protein and a virulence determinant of M type 2 Streptococcus pyogenes
13. Pathogenesis of group A streptococcal infections
14. Group A streptococcal isolate 64/14 expresses surface plasmin-binding structures in addition to Plr
15. Use of the lactococcal nisA promoter to regulate gene expression in gram-positive bacteria: Comparison of induction level and promoter strength
16. Complete genome sequence of an M1 strain of Streptococcus pyogenes
17. Conservation of a hexapeptide sequence in the anchor region of surface proteins from gram-positive cocci
18. Protein F, a fibronectin-binding protein, is an adhesin of the group A streptococcus Streptococcus pyogenes
19. Expression of protein F, the fibronectin-binding protein of Streptococcus pyogenes JRS4, in heterologous streptococcal and enterococcal strains promotes their adherence to respiratory epithelial cells
20. Nucleotide substitutions and small-scale insertion produce size and antigenic variation in group A streptococcal M1 protein
21. CotM of Bacillus subtilis, a member of the alpha-crystallin family of stress proteins, is induced during development and participates in spore outer coat formation
22. Identification of a lysin associated with a bacteriophage (A25) virulent for group A streptococci
23. Complete nucleotide sequence of type 6 M protein of the group A Streptococcus. Repetitive structure and membrane anchor
24. Role of M protein in pharyngeal colonization by group A streptococci in rats
25. Isolation and characterization of genetic expression and secretion signals from Enterococcus faecalis through the use of broad-host-range alpha-amylase probe vectors
26. Expression of the Arp protein, a member of the M protein family, is not sufficient to inhibit phagocytosis of Streptococcus pyogenes
27. Structure of sortase, the transpeptidase that anchors proteins to the cell wall of Staphylococcus aureus
28. Improved pattern for genomebased screening identifies novel cell wall-attached proteins in gram-positive bacteria
29. Intranasal immunization with C5a peptidase prevents nasopharyngeal colonization of mice by the group A Streptococcus
30. C5a peptidase alters clearance and trafficking of group A streptococci by infected mice
31. Biological and immunochemical identity of M protein on group G streptococci with M protein on group A streptococci
32. Immunochemical localization and amino acid sequences of crossreactive epitopes within the group A streptococcal M6 protein
33. Current knowledge of the type specific M antigens of group A streptococci
34. Identification and characterization of the scl gene encoding a group A Streptococcus extracellular protein virulence factor with similarity to human collagen
35. Identification and characterization of a second extracellular collagen-like protein made by group A Streptococcus: Control of production at the level of translation
36. comYA, a gene similar to comGA of Bacillus subtilis, is essential for competence factor-dependent DNA transformation in Streptococcus gordonii
37. A role for trigger factor and an rgg-like regulator in the transcription, secretion and processing of the cysteine proteinase of Streptococcus pyogenes
38. Staphylococcus aureus sortase mutants defective in the display of surface proteins and in the pathogenesis of animal infections
39. Staphylococcus aureus sortase, an enzyme that anchors surface proteins to the cell wall
40. Sortase-catalysed anchoring of surface proteins to the cell wall of Staphylococcus aureus
41. Spa contributes to the virulence of type 18 group A streptococci
42. Affinity purification and characterization of a fibrinogen-binding protein complex which protects mice against lethal challenge with Streptococcus equi subsp. equi
43. Proteolytic cleavage and cell wall anchoring at the LPXTG motif of surface proteins in gram-positive bacteria
44. Anchor structure of staphylococcal surface proteins. II. COOH-terminal structure of muramidase and amidase-solubilized surface protein
45. Prevention and elimination of upper respiratory colonization of mice by group A streptococci by using a bacteriophage lytic enzyme
46. Initiation of biofilm formation in Pseudomonas fluorescens WCS365 proceeds via multiple, convergent signalling pathways: A genetic analysis
47. An embarrassment of sortases-a richness of substrates?
48. Introduction of the emm6 gene into an emm-deleted strain of Streptococcus pyogenes restores its ability to resist phagocytosis
49. Cell wall anchoring of the Streptococcus pyogenes M6 protein in various lactic acid bacteria
50. Cloning in Bacillus subtilis of an extremely thermostable alpha amylase: Comparison with other cloned heat-stable alpha amylases
51. Use of the Escherichia coli β-glucuronidase (gusA) gene as a reporter gene for analyzing promoters in lactic acid bacteria
52. Unique regulation of SclB-a novel collagen-like surface protein of Streptococcus pyogenes
53. SclA, a novel collagen-like surface protein of Streptococcus pyogenes
54. Protein GRAB of Streptococcus pyogenes regulates proteolysis at the bacterial surface by binding alpha2-macroglobulin
55. A role for the fibrinogen-binding regions of streptococcal M proteins in phagocytosis resistance
56. Peptidoglycan types of bacterial cell walls and their taxonomic implications
57. Sequence and structural characteristics of the trypsin-resistant T6 surface protein of group A streptococci
58. Cell wall sorting signals in surface proteins of gram-positive bacteria
59. + by transfer of a plasmid containing an M6 gene
60. Relationship of M protein genes in group A streptococci
61. Protein F: An adhesin of Streptococcus pyogenes binds fibronectin via two distinct domains
62. Production and biological properties of M-protein of Streptococcus equi
63. Simultaneous production and purification of Bacillus subtilis alpha-amylase
64. Fba, a novel fibronectin-binding protein from Streptococcus pyogenes, promotes bacterial entry into epithelial cells, and the fba gene is positively transcribed under the Mga regulator
65. Purification and characterization of sortase, the transpeptidase that cleaves surface proteins of Staphylococcus aureus at the LPXTG motif
66. 3 substrates
67. Anchor structure of staphylococcal surface proteins IV. Inhibitors of the cell wall sorting reaction
68. Characterization of the Lactococcus lactis lactose operon promoter: Contribution of flanking sequences and LacR repressor to promoter activity
69. Streptococcus pyogenes sclB encodes a putative hypervariable surface protein with a collagen-like repetitive structure
70. Antiopsonic activity of fibrinogen bound to M protein on the surface of group A streptococci