Effects of acetate on lipid metabolism in muscles and adipose tissues of type 2 diabetic otsuka long-evans tokushima fatty (OLETF) Rats

Bioscience, Biotechnology and Biochemistry

Volumn 73, Issue 3, 2009, Pages 570-576

  Yamashita, Hiromi ^a   Maruta, Y Hitomi ^a   Jozuka, Michiyo ^a   Kimura, Rie ^a   Iwabuchi, Hiromi ^a   Yamato, Makiko ^a   Saito, Tsukasa ^a   Fujisawa, Katsuhiko ^a   Takahashi, Yoshitaka ^a   Kimoto, Masumi ^a   Hiemori, Miki ^a   Tsuji, Hideaki ^a  

^a OKAYAMA PREFECTURAL UNIVERSITY   (Japan)

Author keywords

Acetate; Adipose tissue; Lipid metabolism; Obesity; Otsuka long evans Tokushima Fatty (OLETF) rats

Indexed keywords

ACETATE; ADIPOSE TISSUE; LIPID METABOLISM; OBESITY; OTSUKA LONG-EVANS TOKUSHIMA FATTY (OLETF) RATS;

BIOCHEMISTRY; GENES; HISTOLOGY; METABOLISM; NUTRITION; OXYGEN; RATS; SUGAR (SUCROSE);

MUSCLE;

ACETIC ACID DERIVATIVE; ADENOSINE PHOSPHATE; ADENOSINE TRIPHOSPHATE; GLUCOSE TRANSPORTER 4; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MESSENGER RNA; MYOGLOBIN; OXYGEN; SLC2A4 PROTEIN, RAT;

ABDOMINAL WALL MUSCULATURE; ADIPOSE TISSUE; ANIMAL; ARTICLE; BROWN ADIPOSE TISSUE; DRUG EFFECT; ENERGY METABOLISM; GENE EXPRESSION REGULATION; GENETICS; LIPID METABOLISM; MALE; METABOLISM; NON INSULIN DEPENDENT DIABETES MELLITUS; OTSUKA LONG EVANS TOKUSHIMA FATTY RAT; PATHOLOGY; PHOSPHORYLATION; RAT; SKELETAL MUSCLE; WHITE ADIPOSE TISSUE;

ABDOMINAL MUSCLES; ACETATES; ADENOSINE MONOPHOSPHATE; ADENOSINE TRIPHOSPHATE; ADIPOCYTES, BROWN; ADIPOCYTES, WHITE; ADIPOSE TISSUE; AMP-ACTIVATED PROTEIN KINASES; ANIMALS; DIABETES MELLITUS, TYPE 2; ENERGY METABOLISM; GENE EXPRESSION REGULATION; GLUCOSE TRANSPORTER TYPE 4; LIPID METABOLISM; MALE; MUSCLE, SKELETAL; MYOGLOBIN; OXYGEN; PHOSPHORYLATION; RATS; RATS, INBRED OLETF; RNA, MESSENGER;

RATTUS;

EID: 65349194988     PISSN: 09168451     EISSN: 13476947     Source Type: Journal    
DOI: 10.1271/bbb.80634     Document Type: Article

References (43)

1. Boden, G., Jadall, R, White, J., Liang, Y., Mozzoli, M., Chen, X., Coleman, E., and Smith, C, Effects of fat on insulin-stimulated carbohydrate metabolism in normal men. J. Clin. Invest., 88, 960-966 (1991).
2. Roden, M., Price, T. B., Perseghin, G., Petersen, K. F., Rothman, D. L., Cline, G. W., and Shulman, G. I., Mechanism of free fatty acid-induced insulin resistance in humans. J. Clin. Invest., 97, 2859-2865 (1996).
3. Magnan, C, Gilbert, M., and Kahn, B. B., Chronic free fatty acid infusion in rats results in insulin resistance but no alteration in insulin-responsive glucose transporter levels in skeletal muscle. Lipids, 31, 1141-1149 (1996).
4. Dresner, A., Laurent, D., Marcucci, M., Griffin, M. E., Dufour, S., Cline, G. W., Slezak, L. A., Andersen, D. K., Hundal, R. S., Rothman, D. L., Petersen, K. F., and Shulman, G. I., Effect of free fatty acids on glucose transport and IRS-1-associated phosphatidylinositol 3-kinase activity. J. Clin. Invest., 103, 253-259 (1999).
5. Yamashita, H., Fujisawa, K., Ito, E., Idei, S., Kawaguchi, N., Kimoto, M., Hiemori, M., and Tsuji, H., Improvement of obesity and glucose tolerance by acetate in type 2 diabetic Otsuka Long-Evans Tokushima Fatty (OLE?R) rats. Biosci. Biotechnol. Biochem., 71, 1236-1243 (2007).
6. Yamashita, H., Kaneyuki, T., and Tagawa, K., Production of acetate in the liver and its utilization in peripheral tissues. Biochim. Biophys. Acta, 1532, 79-87 (2001).
7. Moore, F., Weekes, J., and Hardie, D. G., Evidence that AMP triggers phosphorylation as well as direct allosteric activation of rat liver AMP-activated protein kinase. Eur. J. Biochem., 199, 691-697 (1991).
8. Winder, W. W., and Hardie, D. G., Inactivation of acetyl-CoA carboxylase and activation of AMP-activated protein kinase in muscle during exercise. Am. J. Physiol. Endocrinol. Metab., 270, E299-E304 (1996).
9. Dyck, J. R. B., Kudo, N., Barr, A. J., Davies, S. P., Hardie, D. G., and Lopaschuk, G. D., Phosphorylation control of cardiac acetyl-CoA carboxylase by cAMP-dependent protein kinase and 5'-AMP activated protein kinase. Eur. J. Biochem., 262, 184-190 (1999).
10. Hardie, D. G., Carling, D., and Carlson, M., The AMP-activated/SNFl protein kinase subfamily: metabolic sensors of the eukaryotic cell? Annu. Rev. Biochem., 67, 821-855 (1998).
11. Winder, W. W., and Hardie, D. G., AMP-activated protein kinase, a metabolic master switch: possible roles in type 2 diabetes. Am. J. Physiol. Endocrinol. Metab., 277, E1-E10 (1999).
12. Hardie, D. G., The AMP-activated protein kinase cascade: the key sensor of cellular energy status. Endocrinology, 144, 5179-5183 (2003).
13. Kim, J. K., Fillmore, J. J., Chen, Y., Yu, C, Moore, I. K., Pypaert, M., Lutz, E. P., Kako, Y., Velez-Carrasco, W., Goldberg, I. J., Breslow, J. L., and Shulman, G. I., Tissue-specific overexpression of lipoprotein lipase causes tissue-specific insulin resistance. Proc. Natl. Acad. Sci. USA, 98, 7522-7527 (2001).
14. Baron, A. D., Brechtel, G., Wallace, P., and Edelman, S. V., Rates and tissue sites of non-insulin- and insulin-mediated glucose uptake in humans. Am. J. Physiol. Endocrinol. Metab., 255, E769-E774 (1988).
15. Yamashita, H., Takenoshita, M., Sakurai, M., Braick, R. K., Henzel, W. J., Shillinglaw, W., Arnot, D., and Uyeda, K., A glucose-responsive transcription factor that regulates carbohydrate metabolism in the liver. Proc. Natl. Acad. Sci. USA, 98, 9116-9121 (2001).
16. Kawaguchi, T., Takenoshita, M., Kabashima, T., and Uyeda, K., Glucose and cAMP regulate the L-type pyruvate kinase gene by phosphorylation/ dephosphorylation of the carbohydrate response element binding protein. Proc. Natl. Acad. Sci. USA, 98, 13710-13715 (2001).
17. Iizuka, K., Bruick, R. K., Liang, G., Horton, J. D., and Uyeda, K., Deficiency of carbohydrate response element-binding protein (ChREBP) reduces lipogenesis as well as glycolysis. Proc. Natl. Acad. Sci. USA, 101, 7281-7286 (2004).
18. Ishi, S., Iizuka, K., Miller, B. C, and Uyeda, K., Carbohydrate response element binding protein directly promotes lipogenic enzyme gene transcription. Proc. Natl. Acad. Sci. USA, 101, 15597-15602 (2004).
19. Kawaguchi, T., Osatomi, K., Yamashita, H., Kabashima, T., and Uyeda, K., Mechanism for fatty acid "sparing" effect on glucose-induced transcription. J. Biol. Chem., 277, 3829-3835 (2002).
20. Itsuki-Yoneda, A., Kimoto, M., Tsuji, H., Hiemori, M., and Yamashita, H., Effect of a hypolipidemic drug, Di (2-ethyl-hexyl) phthalate, on mRNA-expression associated fatty acid and acetate metabolism in rat tissues. Biosci. Biotechnol. Biochem., 71, 414-420 (2007).
21. Wittenberg, B. A., and Wittenberg, J. B., Transport of oxygen in muscle. Annu. Rev. Physiol., 51, 857-878 (1989).
22. Kantous, S. B., Dimichele, L. V., Cowan, D. F., and Davis, R. W., High aerobic capacities in the skeletal muscles of pinnipeds: adaptations to diving hypoxia. J. Appl. Physiol., 86, 1247-1256 (1999).
23. Neufer, P. D., Ordway, G. A., and Williams, R. S., Transient regulation of c-fos, aB-crystallin, and hsp70 in muscle during recovery from contractile activity. Am. J. Physiol. Cell Physiol., 274, C341-C346 (1998).
24. Underwood, L. E., and Williams, R. S., Pretranslational regulation of myoglobin gene expression. Am. J. Physiol. Cell Physiol., 252, C450-C453 (1987).
25. Holloszy, J. O., and Booth, F. W., Biochemical adaptations to endurance exercise in muscle. Annu. Rev. Physiol., 38, 273-291 (1976).
26. Black, B. L., Molkentin, J. D., and Olson, E. N., Multiple roles for the MyoD basic region in transmission of transcriptional activation signals and interaction with MEF2. Mol. Cell. Biol., 18, 69-77 (1998).
27. Kaushal, S., Schneider, J. W., Nadal-Ginard, B., and Mahdavi, V., Activation of the myogenic lineage by MEF2A, a factor that induces and cooperates with MyoD. Science, 266, 1236-1240 (1994).
28. Molkentin, J. D., Black, B. L., Martin, J. F., and Olson, E. N., Cooperative activation of muscle gene expression by MEF2 and myogenic bHLH proteins. Cell, 83, 1125-1136 (1995).
29. Grayson, J., Williams, R. S., Yu, Y.-T., and Bassel-Duby, R., Synergistic interactions between heterologous upstream activation elements and specific TATA sequences in a muscle-specific promoter. Mol. Cell. Biol, 15, 1870-1878 (1995).
30. Black, B. L., and Olson, E. N., Transcriptional control of muscle development by myocyte enhancer factor-2 (MEF2) proteins. Annu. Rev. Cell Dev. Biol, 14, 167-196 (1998).
31. Lin, J., Wu, H., Tarr, P. T., Zhang, C.-Y., Wu, Z., Boss, O., Michael, L. F., Puigserver, P., Isotani, E., Olson, E. N., Lowell, B. B., Bassel-Duby, R., and Spiegelman, B. M., Transcriptional co-activator PGC-la drives the formation of slow-twitch muscle fibres. Nature, 418, 797-801 (2002).
32. Al-Khalili, L., Chibalin, A. V., Yu, M., Sjodin, B., Nylen, C, Zierath, J. R., and Krook, A., MEF2 activation in differentiated primary human skeletal muscle cultures requires coordinated involvement of parallel pathways. Am. J. Physiol. Cell Physiol, 286, C1410-C1416 (2004).
33. Thai, M. V., Guruswamy, S., Cao, K. T., Pessin, J. E., and Olson, A. L., Myocyte enhancer factor 2 (MEF2)-binding site is required for GLUT4 gene expression in transgenic mice. J. Biol. Chem., 273, 14285-14292 (1998).
34. Holmes, B. F., Sparling, D. P., Olson, A. L., Winder, W. W., and Dohm, G. L., Regulation of muscle GLUT4 enhancer factor and myocyte enhancer factor 2 by AMP-activated protein kinase. Am. J. Physiol. Endocrinol. Metab., 289, E1071-E1076 (2005).
35. Gray, S., Feinberg, M. W., Hull, S., Kuo, C. T., Watanabe, M., Sen, S., DePina, A., Haspel, R., and Jain, M. K., The Kruppel-like factor KLF15 regulates the insulin-sensitive glucose transporter GLUT4. J. Biol. Chem., 277, 34322-34328 (2002).
36. Wu, X., Motoshima, H., Mahadev, K., Stalker, T. J., Scalia, R., and Goldstein, B. J., Involvement of AMP-activated protein kinase in glucose uptake stimulated by the globular domain of adiponectin in primary rat adipocytes. Diabetes, 52, 1355-1363 (2003).
37. Yamauchi, T., Kamon, J., Minokoshi, Y., Ito, Y., Waki, H., Uchida, S., Yamashita, S., Noda, M., Kita, S., Ueki, K., Eto, K., Akanuma, Y., Froguel, P., Foufelle, F., Ferre, P., Carling, D., Kimura, S., Nagai, R., Kahn, B. B., and Kadowaki, T., Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase. Nat. Med., 8, 1288-1295 (2002).
38. Zhou, G., Myers, R., Li, Y., Chen, Y., Shen, X., Fenyk-Melody, J., Wu, M., Ventre, J., Doebber, T., Fujii, N., Musi, N., Hirshman, M. F., Goodyear, L. J., and Moller, D. E., Role of AMP-activated protein kinase in mechanism of metformin action. J. Clin. Invest., 108, 1167-1174 (2001).
39. Fryer, L. G. D., Parbu-Patel, A., and Carling, D., The anti-diabetic drugs rosiglitazone and metformin stimulate AMP-activated protein kinase through distinct signaling pathways. J. Biol. Chem., 277, 25226-25232 (2002).
40. Orci, L., Cook, W. S., Ravazzola, M., Wang, M., Park, B.-H., Montesano, R., and Unger, R. H., Rapid transformation of white adipocytes into fat-oxidizing machines. Proc. Natl. Acad. Sci. USA, 101, 2058-2063 (2004).
41. Daval, M., Diot-Dupuy, F., Bazin, R., Hainault, I., Viollet, B., Vaulont, S., Hajduch, E., Ferre, P., and Foufelle, F., Anti-lipolytic action of AMP-activated protein kinase in rodent adipocytes. J. Biol. Chem., 280, 25250-25257 (2005).
42. Lihn, A. S., Jessen, N., Pedersen, S. B., Lund, S., and Richelsen, B., AICAR stimulates adiponectin and inhibits cytokines in adipose tissue. Biochem. Biophys. Res. Commun., 316, 853-858 (2004).
43. Sell, H., Dietze-Schroeder, D., Eckardt, K., and Eckel, J., Cytokine secretion by human adipocytes is differentially regulated by adiponectin, AICAR, and troglitazone. Biochem. Biophys. Res. Commun., 343, 700-706 (2006).