ARF6-mediated endosome recycling reverses lipid accumulation defects in Niemann-Pick type C disease

PLoS ONE

Volumn 4, Issue 4, 2009, Pages

  Schweitzer, Jill Kuglin ^a   Pietrini, Sean D ^a   D'Souza Schorey, Crislyn ^a  

^a UNIVERSITY OF NOTRE DAME   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE DIPHOSPHATE RIBOSYLATION FACTOR 6; CHOLESTEROL; SPHINGOLIPID; 3 BETA (2 (DIETHYLAMINO)ETHOXY)ANDROST 5 EN 17 ONE; 3-BETA-(2-(DIETHYLAMINO)ETHOXY)ANDROST-5-EN-17-ONE; ADENOSINE DIPHOSPHATE RIBOSYLATION FACTOR; ADP-RIBOSYLATION FACTOR 6; ANDROSTANE DERIVATIVE; FILIPIN; HYBRID PROTEIN; HYPOCHOLESTEROLEMIC AGENT; LAMP1 PROTEIN, HUMAN; LYSOSOME ASSOCIATED MEMBRANE PROTEIN; SMALL INTERFERING RNA;

ARTICLE; CELL LEVEL; CELL STIMULATION; CELL TRANSPORT; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; ENDOSOME; FIBROBLAST; HUMAN; HUMAN CELL; LIPID STORAGE; NIEMANN PICK DISEASE; PHENOTYPE; PROTEIN FUNCTION; GENETICS; GOLGI COMPLEX; HELA CELL; LIPID METABOLISM; METABOLISM; PATHOPHYSIOLOGY; ULTRASTRUCTURE;

ADP-RIBOSYLATION FACTORS; ANDROSTENES; ANTICHOLESTEREMIC AGENTS; CHOLESTEROL; ENDOSOMES; FILIPIN; GOLGI APPARATUS; HELA CELLS; HUMANS; LIPID METABOLISM; LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEINS; NIEMANN-PICK DISEASE, TYPE C; RECOMBINANT FUSION PROTEINS; RNA, SMALL INTERFERING;

EID: 65349184122     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0005193     Document Type: Article

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