Investigation of a nanoemulsion as vehicle for transdermal delivery of amlodipine

Pharmazie

Volumn 64, Issue 2, 2009, Pages 80-85

  Kumar, D ^a   Aqil, Mohammed ^a   Rizwan, M ^a   Sultana, Y ^a   Ali, M ^a  

^a HAMDARD UNIVERSITY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

AMLODIPINE; DIETHYLENE GLYCOL MONOETHYL ETHER; OLEIC ACID; POLYSORBATE 20; WATER; CALCIUM CHANNEL BLOCKING AGENT; DRUG VEHICLE; NANOPARTICLE; OIL; SURFACTANT;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CHEMICAL COMPOSITION; DRUG DELIVERY SYSTEM; DRUG DESIGN; DRUG FORMULATION; DRUG PENETRATION; DRUG SOLUBILITY; DRUG STABILITY; DRUG STRUCTURE; NANOEMULSION; NONHUMAN; PARTICLE SIZE; PH; RAT; SKIN PERMEABILITY; THERMOSTABILITY; VISCOSITY; ANIMAL; BIOAVAILABILITY; CHEMISTRY; EMULSION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INTRADERMAL DRUG ADMINISTRATION; SKIN ABSORPTION; THERMODYNAMICS; TRANSMISSION ELECTRON MICROSCOPY; VEHICLES;

ADMINISTRATION, CUTANEOUS; AMLODIPINE; ANIMALS; BIOLOGICAL AVAILABILITY; CALCIUM CHANNEL BLOCKERS; CHEMISTRY, PHARMACEUTICAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; EMULSIONS; HYDROGEN-ION CONCENTRATION; MICROSCOPY, ELECTRON, TRANSMISSION; NANOPARTICLES; OILS; PARTICLE SIZE; RATS; SKIN ABSORPTION; SURFACE-ACTIVE AGENTS; THERMODYNAMICS; VEHICLES; VISCOSITY;

EID: 65349175069     PISSN: 00317144     EISSN: None     Source Type: Journal    
DOI: 10.1691/ph.2009.8200     Document Type: Article

References (19)

1. Alvarez-Figueroa MJ, Blanco-Mendez J (2001) Transdermal delivery of MTX: ionophoretic delivery from hydrogels and passive delivery from microemulsions. Int J Pharm 215: 57-65.
2. Baroli B, Lopez-Quintela, MA, Delgado-Charro MB, Fadda, AM, Blanco-Mendez J (2000) Microemulsions for topical delivery of 8-methoxsalen. Int J Pharm 69: 209-218.
3. Chen H, Chang X, Du D, Li J, Xu H, Yang H (2006) Microemulsionbased hydrogel formulation of ibuprofen for topical delivery. Int J Pharm 315: 52-58.
4. Chen H, Chang X, Weng T, Zhao X, Gao Z, Yang Y, Xu, H,Yang X (2004) A study of microemulsion systems for transdermal delivery of triptolide. J Contr Release 98: 427-436.
5. Higuchi T (1960) Physical chemical analysis of percutaneous absorption process from creams and ointments. J Soc Cosmet Meter 11: 85-97.
6. Kreilgaard M (2002) Influence of microemulsions on cutaneous drug delivery. Adv Drug Deliv Rev. 54 (Suppl. 1): S77-S98.
7. Krishnaiah YSR, Satyanarayana V, Bhaskar P (2003) Formulation and In Vivo Evaluation of Membrane-Moderated Transdermal Therapeutic Systems of Nicardipine Hydrochloride using Carvone as a Penetration Enhancer. Drug Deliv 10: 101-109.
8. Ktistis G, Niopas I (1998) A study on the in-vitro percutaneous absorption of propranolol from disperse systems. J Pharm Pharmacol 50: 413-418.
9. Lawrence MJ, Rees GD (2000) Microemulsion-based media as novel drug delivery systems. Adv Drug Deliv Rev 45: 89-121.
10. Lopez A, Linares F, Cortell C, Herraez M (2000) Comparative enhancer effects of Span®20 with Tween®20 and Azone® on the in vitro percutaneous penetration of compounds with different lipophilicities. Int J Pharm 202: 133-140.
11. McDaid DM, Deasy PB (1996) Formulation development of a transdermal drug delivery system for amlodipine base. Int J Pharm 133: 71-83.
12. Mohammadia A, Rezanour N, Dogahehc MA, Bidkorbeh FG, Hashemb M, Walker RB (2007) A stability-indicating high performance liquid chromatographic (HPLC) assay for the simultaneous determination of atorvastatin and amlodipine in commercial tablets. J Chromatogr B 846: 215-221.
13. Peltola S, Saarinen-Savolainen P, Kiesvaara J, Suhonen TM, Urtti A (2003) Microemulsions for topical delivery of estradiol. Int J Pharm 254: 99-107.
14. Pershing LK, Parry GE, Lambert LD (1993). Disparity of in vitro and in vivo oleic acid-enhanced-estradiol percutaneous absorption across human skin. Pharm Res 10: 1745-1750.
15. Rhee YS, Choi JG, Park ES, Chi SC (2001) Transdermal delivery of ketoprofen using microemulsions. Int J Pharm 228: 161-170.
16. Sintov AC, Shaprio L (2004) New microemulsions vehicle facilitates percutaneous penetration in-vitro and cutaneous drug bioavailability invivo. J Control Release 95: 173-183.
17. Williams DM, Cubeddu LX (1998) Amlodipine phamacokinetics in healthy volunteers. J Clin Pharmacol 28: 990-994.
18. Yuan Y, Li S, Mo F, Zhong D (2006). Investigation of microemulsion system for transdermal delivery of meloxicam. Int J Pharm 321: 117-123.
19. Zhao X, Liu JP, Zhang X, Li Y (2006). Enhancement of transdermal delivery of theophylline using microemulsion vehicle. Int J Pharm 327: 58-64.