Formulation and in vivo evaluation of membrane-moderated transdermal therapeutic systems of nicardipine hydrochloride using carvone as a penetration enhancer

Drug Delivery: Journal of Delivery and Targeting of Therapeutic Agents

Volumn 10, Issue 2, 2003, Pages 101-109

  Krishnaiah, Y S R ^a   Satyanarayana, V ^a   Bhaskar, P ^a  

^a ANDHRA UNIVERSITY   (India)

Author keywords

Carvone; EVA 2825 Membrane; In Vivo Evaluation; Nicardipine Hydrochloride; Transdermal Drug Delivery

Indexed keywords

ADHESIVE AGENT; CARVONE; ETHYLENE VINYL ACETATE COPOLYMER; HYDROXYPROPYLCELLULOSE; NICARDIPINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG FORMULATION; DRUG PENETRATION; DRUG POTENTIATION; DRUG SCREENING; DRUG TRANSPORT; MALE; MEMBRANE; NONHUMAN; PRIORITY JOURNAL; RAT; SKIN;

EID: 0038025864     PISSN: 10717544     EISSN: None     Source Type: Journal    
DOI: 10.1080/713840367     Document Type: Article

References (33)

1. Akimoto, T., Aoyagi, T., Minoshima, J., and Nagase, Y. 1997. Polymeric percutaneous drug penetration enhancer synthesis and enhancing property of PEG/PDMS block copolymer with a cationic end group. J. Contrl. Rel. 49:229-241.
2. Cornwell, P., and Barry, B. 1991. Sequiterpene components of volatile oil as skin penetration enhancers for the hydrophilic permeant 5-fluorouracil. J. Pharm. Pharmacol. 46:261-269.
3. Cornwell, P., and Barry, B. 1994. Wide angle X-ray diffarction of human stratum corneum effect of hydration and terpene enhancer treatment. J. Pharm. Pharmacol. 46:938-950.
4. Dow, R. J., and Graham, D. J. M. 1986. A review of the human metabolism and pharmacokinetics of nicardipine hydrochloride. Br. J. Clin. Pharmacol. 22:1955-2025.
5. Gao, S., and Singh, J. 1998. In vitro percutaneous absorption enhancement of lipophilic drug tamoxifen by terpenes. J. Contrl. Rel. 51:193-199.
6. Graham, D. J. M., Dow, R. J., Hall, D. J., Alexander, O. F., Mroszczat, E. J., and Freedman, D. 1985. The metabolism and pharmacokinetics of nicardipine hydrochloride in man. Br. J. Clin. Pharmacol. 20:235-285.
7. Hayton, W. L., and Chen, T. 1982. Correction of perfusate concentration samples removal. J. Pharm. Sci. 71:820-821.
8. Ho, H. O., Chen, L. C., Lin, H. M., and Sheu, M. T. 1998. Penetration enhancement by limonene combined with a solubulization effect in a solvent system. J. Contrl. Rel. 51:301-311.
9. Hori, M., Satoh, S., Maibach, H. I., and Gug, R. H. 1991. Enhancement of propranolol hydrochloride and diazepam skin absorption in vitro: Effect of enhancer lipophilicity. J. Pharm. Sci. 80:32-35.
10. Hunt, J. N. 1951. Gastric emptying and secretion in man. Physiol. Rev. 39:491.
11. Hunt, J. N., and Spurgel, W. R. 1951. Pattern of emptying of the human stomach. J. Pysiol. 113:157.
12. Iwasa, A., Irimoto, K., Kasai, S., Okuyama, H., and Nagai, T. 1991. Effect of non-ionic surfactant on percutaneous absorption of diclofenac sodium. Yakuzaigaku. 51:16-21.
13. Jain, S. K., Vyas, S. P., and Dixit, V. K. 1990. Effective and controlled transdermal delivery of ephedrine. J. Contrl. Rel. 12:257-263.
14. Julraht, K., Keith, A. P., and James, A. W. 1995. Development of a transdermal delivery device for melotoin in vitro study. Drug Dev. Ind. Pharm. 21:1377-1387.
15. Kim, Y., Ghanem, A., and Higuchi, W. 1992. Model studies of epidermal permeability. Semin. Dermatol. 11:145-156.
16. Kim, M. K., Zhao, H., Lee, C. H., and Kim, D. D. 2001. Formulation of reservoirtype testosterone transdermal delivery system. Int. J. Pharm. 219:51-59.
17. Krishnaiah, Y. S. R., Satyanarayana, V., and Karthikeyan, R. S. 2002. Penetration enhancing effect of menthol on the percutaneous absorption of nicardipine hydrochloride from HPC gel through excised rat epidermis. Pharm. Dev. Tech. 7:305-315.
18. Krishnaiah, Y. S. R., Satyanarayana, V., and Karthikeyan, R. S. 2002a. Effect of solvent system on the in vitro permeability of nicardipine hydrochloride through excised rat epidermis. J. Pharm. Pharmaceut. Sci. 5:2124-2131.
19. Krishnaiah, Y. S. R., Satyanarayana, V., and Bhaskar, P. 2002b. Effect of carvone on the permeation of nicardipine hydrochloride across the excised rat abdominal skin. Drug Dev. Ind. Pharm. 29:191-202.
20. Krishnaiah, Y. S. R., Satyanarayana, V., and Bhaskar, P. 2002c. Effect of menthol on the in vivo performance of membrane-moderated transdermal therapeutic system of nicardipine hydrochloride in human volunteers. Eur. J. Pharm. Biopharm. (In press).
21. Krishnaiah, Y. S. R., Satyanarayana, V., and Bhaskar, P. 2002d. Influence of limonene on the bioavailability of nicardipine hydrochloride transdermal therapeutic systems in human volunteers. Int. J. Pharm. 247:91-102.
22. Michniak, B., Player, M. R., Chapman, J. M., and Sowell, J. W. 1994. Azone analogues as penetration enhancers: Effect of different vehicles on hydrocortisone acetate skin permeation and retention. J. Contrl. Rel. 32:147-154.
23. Moghimi, H., Williams, A., and Barry, B. 1996. A lamellar matrix for stratum corneum intercellular lipids. IV. Effects of terpene penetration enhancers on the permeation of 5-fluorouracil and oestradiol through the matrix. Int. J Pharm. 145:49-59.
24. Moghimi, H., Williams, A., and Barry, B. 1997. A lamellar matrix model for stratum corneum intercellular lipids. V. Effects of terpene penetration enhancers on the structure and thermal behavior of matrix. Int. J. Pharm. 146:41-54.
25. Obata, Y., Takayama, K., Machida, Y., and Nagai, T. 1991. Combined effect of cyclic monoterpenes and ethanol on percutaneous absorption of diclofenac sodium. Drug Des. Deliv. 8:137-144.
26. Okabe, H., Obata, Y., Takayama, K., and Nagai, T. 1990. Percutaneous absorption enhancing effect and skin irritation of monocyclic monoterpenes. Drug Des. Deliv. 6:229.
27. Opdyke, D. 1979. Monographs on fragrance raw materials. Food Cosmet. Toxicol. I (suppl.):11-17.
28. Pfister, W., Dean, S., and Hsieh, S. 1990. Permeation enhancers compatible with transdermal drug delivery systems. I. Selection and formulation considerations. Pharm. Tech. 8:132-140.
29. Santo, S., Hirotani, Y., Ogura, N., Sasaki, E., and Kitagawa, S. 1998. Enhancing effect of N-dodecyl-2-pyrrolidone on the percutaneous absorption of 5fluorouracil derivatives. Chem. Pharm. Bull. 46:831-836.
30. Tanojo, H., Bouwstra, J., Juninger, H., and Bodde, H. 1997. In vitro human skin barrier modulation by fatty acids: Skin permeation and thermal analysis studies. Pharm. Res. 14:42-49.
31. Williams, A., and Barry, B. 1991. Terpenes and the lipid-protein partitioning theory of skin penetration enhancement. Pharm. Res. 8:17-24.
32. Yamune, M., Williams, A., and Barry, B. 1995. Terpenes penetration enhancers in propylene glycol/water co-solvent systems: Effectiveness and mechanism of action. J. Pharm. Pharmacol. 47:978-989.
33. Zhao, K., and Singh, J. 1999. In vitro percutaneous absorption enhancement of propranolol hydrochloride through porcine epidermis by terpenes/ethanol. J. Contrl. Rel. 62:359-366.