Amlodipine Pharmacokinetics in Healthy Volunteers

The Journal of Clinical Pharmacology

Volumn 28, Issue 11, 1988, Pages 990-994

  Williams, Dennis M ^a   Cubeddu, Luigi X ^b  

^a School of Medicine   (United States)

^b University of North Carolina   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMLODIPINE;

ADULT; BIOAVAILABILITY; BLOOD PRESSURE; DOSE RESPONSE; DRUG BLOOD LEVEL; DRUG ELIMINATION; HEADACHE; HEMODYNAMICS; HUMAN; HUMAN EXPERIMENT; MALE; NORMAL HUMAN; ORAL DRUG ADMINISTRATION; PHARMACOKINETICS;

ADULT; AMLODIPINE; BLOOD PRESSURE; CALCIUM CHANNEL BLOCKERS; HALF-LIFE; HUMAN; MALE; NIFEDIPINE; RANDOM ALLOCATION; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0024263032     PISSN: 00912700     EISSN: 15524604     Source Type: Journal    
DOI: 10.1002/j.1552-4604.1988.tb03119.x     Document Type: Article

References (10)

1. The role of calcium channel blockers in the treatment of hypertension
2. Long acting dihydropyridine calcium antagonists. I. 2‐alkoxymethyl derivatives incorporating basic substituents
3. Amlodipine, a new dihydropyridine calcium channel blocker with slow onset and long duration of action
4. Amlodipine, A calcium channel blocker with pharmacokinetic properties novel to dihydropyridines
5. Calcium channel blocking properties of amlodipine in vascular smooth muscle and cardiac muscle in vitro: evidence of voltage modulation of vascular dihydropyridine receptors
6. Amlodipine, A calcium channel blocker with pharmacokinetic properties novel to dihydropyridines
7. Antihypertensive effects of amlodipine, a novel dihydropyridine calcium channel blocker
8. A hemodynamic dose finding study with a new slow‐calcium channel blocker (Amlodipine) in coronary artery disease
9. Improvement of treadmill time to angina by amlodipine
10. The pharmacokinetics of amlodipine in healthy volunteers after single intravenous and oral doses and after 14 repeated oral doses given once daily