Caulerpenyne binding to tubulin: Structural modifications by a non conventional pharmacological agent

Medicinal Chemistry

Volumn 5, Issue 2, 2009, Pages 182-190

  Bourdron, Julien ^a,b   Barbier, Pascale ^a   Allegro, Diane ^a   Villard, Claude ^a   Lafitte, Daniel ^a   Commeiras, Laurent ^b   Parrain, Jean Luc ^b   Peyrot, Vincent ^a  

^a University of the Mediterranean Aix Marseille II   (France)

^b CNRS   (France)

Author keywords

Caulerpenyne; Electrospray; MALDI TOF; Microtubule; Tubulin

Indexed keywords

ALPHA TUBULIN; ANTINEOPLASTIC AGENT; BETA TUBULIN; CAULERPENYNE; COLCHICINE; PACLITAXEL; THIOL GROUP; UNCLASSIFIED DRUG; VINCA ALKALOID; ANTIINFECTIVE AGENT; CRYPTOPHYCIN 52; DEPSIPEPTIDE; LACTAM; LACTONE; SESQUITERPENE; THIOL DERIVATIVE; TRYPSIN; TUBULIN;

ARTICLE; BINDING SITE; CAULERPA; CAULERPA TAXIFOLIA; CONTROLLED STUDY; COVALENT BOND; DRUG PROTEIN BINDING; DRUG SYNTHESIS; MICROTUBULE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN MODIFICATION; PROTEIN STRUCTURE; ANIMAL; BINDING COMPETITION; CHEMICAL STRUCTURE; CHEMISTRY; ISOMERISM; MASS SPECTROMETRY; METABOLISM; PROTEIN BINDING; PROTEIN CONFORMATION; SHEEP; TITRIMETRY; ULTRACENTRIFUGATION; ULTRASTRUCTURE;

ANIMALS; ANTI-BACTERIAL AGENTS; ANTINEOPLASTIC AGENTS; BINDING SITES; BINDING, COMPETITIVE; COLCHICINE; DEPSIPEPTIDES; ISOMERISM; LACTAMS; LACTONES; MICROTUBULES; MODELS, MOLECULAR; PACLITAXEL; PROTEIN BINDING; PROTEIN CONFORMATION; SESQUITERPENES; SHEEP; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; SULFHYDRYL COMPOUNDS; TITRIMETRY; TRYPSIN; TUBULIN; ULTRACENTRIFUGATION;

EID: 65349169465     PISSN: 15734064     EISSN: None     Source Type: Journal    
DOI: 10.2174/157340609787582891     Document Type: Article

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