The active GTP- and ground GDP-liganded states of tubulin are distinguished by the binding of chiral isomers of ethyl 5-amino-2-methyl- 1,2-dihydro-3-phenylpyrido[3,4-b]pyrazin-7-yl carbamate

Biochemistry

Volumn 37, Issue 2, 1998, Pages 758-768

  Barbier, Pascale ^a   Peyrot, Vincent ^a   Leynadier, Daniel ^b   Andreu, José Manuel ^b  

^a CNRS   (France)

^b CENTRO DE INVESTIGACIONES BIOLÓGICAS   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

COLCHICINE; GUANOSINE DIPHOSPHATE; GUANOSINE TRIPHOSPHATE; MAGNESIUM ION; MIVOBULIN ISETHIONATE; TUBULIN;

ANIMAL TISSUE; ARTICLE; BINDING SITE; BRAIN; CATTLE; CHIRALITY; DRUG PROTEIN BINDING; DRUG STRUCTURE; ENANTIOMER; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ISOMERISM; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN PURIFICATION;

GUANOSINE DIPHOSPHATE; GUANOSINE TRIPHOSPHATE; HYDROLYSIS; LIGANDS; MAGNESIUM; MODELS, CHEMICAL; PROTEIN BINDING; PROTEIN CONFORMATION; PYRAZINES; STEREOISOMERISM; TUBULIN;

ANIMALIA; BOS TAURUS; GARCIA;

EID: 0032512421     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi970568t     Document Type: Article

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