-
1
-
-
65349133378
-
-
Cancer Facts and Figures 2005. Surveillance Research. American Cancer Society Inc. Atlanta, USA. 2005;1-60.
-
Cancer Facts and Figures 2005. Surveillance Research. American Cancer Society Inc. Atlanta, USA. 2005;1-60.
-
-
-
-
2
-
-
65349196549
-
-
Statistical Report: Primary Brain Tumors in the United States, 1997-2001. Central Brain Tumor Registry of the United States. Hinsdale, USA. 2004.
-
Statistical Report: Primary Brain Tumors in the United States, 1997-2001. Central Brain Tumor Registry of the United States. Hinsdale, USA. 2004.
-
-
-
-
3
-
-
0000167206
-
Pathology and genetics: Tumors of the nervous system
-
International Agency for Research on Cancer, Albany, USA
-
Kleihues P, Cavenee WK. Pathology and genetics: Tumors of the nervous system. In: World Health Classification of tumors. International Agency for Research on Cancer, Albany, USA. 2000;314.
-
(2000)
World Health Classification of tumors
, pp. 314
-
-
Kleihues, P.1
Cavenee, W.K.2
-
4
-
-
34547122001
-
The 2007 WHO classification of tumours of the central nervous system
-
Louis DN, Ohgaki H, Wiestler OD, et al. The 2007 WHO classification of tumours of the central nervous system. Acta Neuropathol (Berl). 2007;114(2):97-109.
-
(2007)
Acta Neuropathol (Berl)
, vol.114
, Issue.2
, pp. 97-109
-
-
Louis, D.N.1
Ohgaki, H.2
Wiestler, O.D.3
-
5
-
-
0031964497
-
Validation and predictive power of Radiation Therapy Oncology Group (RTOG) recursive partitioning analysis classes for malignant glioma patients: A report using RTOG 90-06
-
Scott CB, Scarantino C, Urtasun R, et al. Validation and predictive power of Radiation Therapy Oncology Group (RTOG) recursive partitioning analysis classes for malignant glioma patients: a report using RTOG 90-06. Int J Radiat Oncol Biol Phys. 1998;40(1):51-55.
-
(1998)
Int J Radiat Oncol Biol Phys
, vol.40
, Issue.1
, pp. 51-55
-
-
Scott, C.B.1
Scarantino, C.2
Urtasun, R.3
-
6
-
-
0032767387
-
Outcomes and prognostic factors in recurrent glioma patients enrolled onto phase II clinical trials
-
Wong ET, Hess KR, Gleason MJ, et al. Outcomes and prognostic factors in recurrent glioma patients enrolled onto phase II clinical trials. J Clin Oncol. 1999;17(8):2572-2578.
-
(1999)
J Clin Oncol
, vol.17
, Issue.8
, pp. 2572-2578
-
-
Wong, E.T.1
Hess, K.R.2
Gleason, M.J.3
-
7
-
-
0037161024
-
Chemotherapy in adult high-grade glioma: A systematic review and meta-analysis of individual patient data from 12 randomised trials
-
Stewart LA. Chemotherapy in adult high-grade glioma: a systematic review and meta-analysis of individual patient data from 12 randomised trials. Lancet. 2002;359(9311):1011-1018.
-
(2002)
Lancet
, vol.359
, Issue.9311
, pp. 1011-1018
-
-
Stewart, L.A.1
-
8
-
-
20044366163
-
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
-
Stupp R, Mason WP, van den Bent MJ, et al. Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med. 2005;352(10):987-996.
-
(2005)
N Engl J Med
, vol.352
, Issue.10
, pp. 987-996
-
-
Stupp, R.1
Mason, W.P.2
van den Bent, M.J.3
-
9
-
-
1942469956
-
MGMT: Its role in cancer aetiology and cancer therapeutics
-
Gerson SL. MGMT: its role in cancer aetiology and cancer therapeutics. Nat Rev Cancer. 2004;4(4):296-307.
-
(2004)
Nat Rev Cancer
, vol.4
, Issue.4
, pp. 296-307
-
-
Gerson, S.L.1
-
10
-
-
20044372154
-
MGMT gene silencing and benefit from temozolomide in glioblastoma
-
Hegi ME, Diserens AC, Gorlia T, et al. MGMT gene silencing and benefit from temozolomide in glioblastoma. N Engl J Med. 2005;352(10):997-1003.
-
(2005)
N Engl J Med
, vol.352
, Issue.10
, pp. 997-1003
-
-
Hegi, M.E.1
Diserens, A.C.2
Gorlia, T.3
-
11
-
-
0033624176
-
O6-alkylguanine-DNA alkyltransferase depletion enhance alkylator activity in the clinic?
-
Friedman HS. Can O6-alkylguanine-DNA alkyltransferase depletion enhance alkylator activity in the clinic? Clin Cancer Res. 2000;6(8):2967-2968.
-
(2000)
Clin Cancer Res
, vol.6
, Issue.8
, pp. 2967-2968
-
-
Can, F.H.S.1
-
12
-
-
27244442921
-
Phase I trial of temozolomide plus O6-benzylguanine for patients with recurrent or progressive malignant glioma
-
Quinn JA, Desjardins A, Weingart J, et al. Phase I trial of temozolomide plus O6-benzylguanine for patients with recurrent or progressive malignant glioma. J Clin Oncol. 2005;23(28):7178-7187.
-
(2005)
J Clin Oncol
, vol.23
, Issue.28
, pp. 7178-7187
-
-
Quinn, J.A.1
Desjardins, A.2
Weingart, J.3
-
14
-
-
0033818764
-
Angiogenesis in malignant primary and metastatic brain tumors
-
Reijneveld JC, Voest EE, Taphoorn MJ. Angiogenesis in malignant primary and metastatic brain tumors. J Neurol. 2000;247:597-608.
-
(2000)
J Neurol
, vol.247
, pp. 597-608
-
-
Reijneveld, J.C.1
Voest, E.E.2
Taphoorn, M.J.3
-
15
-
-
0034757675
-
Vascular endothelial growth factor expression correlates with tumour grade and vascularity in gliomas
-
Chaudhry LH, O'Donovan DG, Brenchley PE, Reid H, Roberts IS. Vascular endothelial growth factor expression correlates with tumour grade and vascularity in gliomas. Histopathology. 2001;39:409-415.
-
(2001)
Histopathology
, vol.39
, pp. 409-415
-
-
Chaudhry, L.H.1
O'Donovan, D.G.2
Brenchley, P.E.3
Reid, H.4
Roberts, I.S.5
-
16
-
-
0041349558
-
The relevance of cell proliferation, vascular endothelial growth factor, and basic fibroblast growth factor production to angiogenesis and tumorigenicity I human glioma cell lines
-
Ke LD, Shi YX, Im SA, Chen X, Yung WK. The relevance of cell proliferation, vascular endothelial growth factor, and basic fibroblast growth factor production to angiogenesis and tumorigenicity I human glioma cell lines. Clin Cancer Res. 2000;6:2562-2572.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 2562-2572
-
-
Ke, L.D.1
Shi, Y.X.2
Im, S.A.3
Chen, X.4
Yung, W.K.5
-
17
-
-
0026446102
-
Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo
-
Plate KH, Breier G, Weich HA, Risau W. Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo. Nature. 1992;359:845-848.
-
(1992)
Nature
, vol.359
, pp. 845-848
-
-
Plate, K.H.1
Breier, G.2
Weich, H.A.3
Risau, W.4
-
18
-
-
0028920358
-
Expression of vascular endothelial growth factor and its possible relation with neovascualarization in human brain tumors
-
Samoto K, Ikezaki K. Ono M, et al. Expression of vascular endothelial growth factor and its possible relation with neovascualarization in human brain tumors. Cancer Res. 1995;55:1189-1193.
-
(1995)
Cancer Res
, vol.55
, pp. 1189-1193
-
-
Samoto, K.1
Ikezaki, K.2
Ono, M.3
-
19
-
-
0038443099
-
Anti-angiogenic therapy: Rationale, challenges and clinical studies
-
Longo R, Sarmiento R, Fanelli M, Capaccetti B, Gattuso D, Gasparini G. Anti-angiogenic therapy: Rationale, challenges and clinical studies. Angiogenesis. 2002;5:237-256.
-
(2002)
Angiogenesis
, vol.5
, pp. 237-256
-
-
Longo, R.1
Sarmiento, R.2
Fanelli, M.3
Capaccetti, B.4
Gattuso, D.5
Gasparini, G.6
-
20
-
-
0027197245
-
Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo
-
Kim KJ, Li B, Winer J, et al. Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo. Nature. 1993;362:841-844.
-
(1993)
Nature
, vol.362
, pp. 841-844
-
-
Kim, K.J.1
Li, B.2
Winer, J.3
-
21
-
-
0030856731
-
Humanization of an anti-vascular endothelial growth factor monoclonal antibody for the therapy of solid tumors and other disorders
-
Presta LG, Chen H, O'Connor SJ, et al. Humanization of an anti-vascular endothelial growth factor monoclonal antibody for the therapy of solid tumors and other disorders. Cancer Res. 1997;57:4593-4599.
-
(1997)
Cancer Res
, vol.57
, pp. 4593-4599
-
-
Presta, L.G.1
Chen, H.2
O'Connor, S.J.3
-
22
-
-
2442621619
-
Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer
-
Ferrara N, Hillan KJ, Gerber H, Novotny W. Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer. Nature Rev Drug Discov. 2004;3:391-400.
-
(2004)
Nature Rev Drug Discov
, vol.3
, pp. 391-400
-
-
Ferrara, N.1
Hillan, K.J.2
Gerber, H.3
Novotny, W.4
-
23
-
-
2542561964
-
Bevacizumab plus Irinotecan, Fluorouracil, and Leucovorin for Metastatic Colorectal Cancer
-
Hurwitz H, Fehrenbacher L, Novotny W, et al. Bevacizumab plus Irinotecan, Fluorouracil, and Leucovorin for Metastatic Colorectal Cancer. N Engl J Med. 2004;350:2335-2342.
-
(2004)
N Engl J Med
, vol.350
, pp. 2335-2342
-
-
Hurwitz, H.1
Fehrenbacher, L.2
Novotny, W.3
-
24
-
-
33845490014
-
Paclitaxel carboplatin alone or with bevacizumab for non-small cell lung cancer
-
Sandler A, Gray R, Perry MC, et al. Paclitaxel carboplatin alone or with bevacizumab for non-small cell lung cancer. N Engl J Med 2006;355:2542-2550.
-
(2006)
N Engl J Med
, vol.355
, pp. 2542-2550
-
-
Sandler, A.1
Gray, R.2
Perry, M.C.3
-
25
-
-
37549040613
-
Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancer
-
Miller K, Wang M, Gralow J, et al. Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancer. N Engl J Med. 2007;357(26):2666-2676.
-
(2007)
N Engl J Med
, vol.357
, Issue.26
, pp. 2666-2676
-
-
Miller, K.1
Wang, M.2
Gralow, J.3
-
26
-
-
33947191055
-
Phase II trial of bevacizumab and irinotecan in recurrent malignant glioma
-
Vredenburgh JJ, Desjardins A, Herndon JE, et al. Phase II trial of bevacizumab and irinotecan in recurrent malignant glioma. Clin Cancer Res. 2007;13(4):1253-1259.
-
(2007)
Clin Cancer Res
, vol.13
, Issue.4
, pp. 1253-1259
-
-
Vredenburgh, J.J.1
Desjardins, A.2
Herndon, J.E.3
-
27
-
-
36049037819
-
Bevacizumab plus irinotecan in recurrent glioblastoma multiforme
-
Vredenburgh J, Desjardins A, Herndon JE, et al. Bevacizumab plus irinotecan in recurrent glioblastoma multiforme. J Clin Oncol. 2007;25:4722-4729.
-
(2007)
J Clin Oncol
, vol.25
, pp. 4722-4729
-
-
Vredenburgh, J.1
Desjardins, A.2
Herndon, J.E.3
-
28
-
-
58149231546
-
Bevacizumab plus irinotecan in recurrent WHO grade III malignant gliomas
-
Desjardins A, Reardon DA, Herndon JE 2nd, et al. Bevacizumab plus irinotecan in recurrent WHO grade III malignant gliomas. Clin Cancer Res. 2008;14:7068-7073.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 7068-7073
-
-
Desjardins, A.1
Reardon, D.A.2
Herndon 2nd, J.E.3
-
29
-
-
65349129191
-
-
Cloughesy TF, Prados MD, Wen PY, et al. A phase II, randomized, non-comparative clinical trial of the effect of bevacizumab (BV) alone or in combination with irinotecan (CPT) on 6-month progression free survival (PFS6) in recurrent, treatment-refractory glioblastoma (GBM). J Clin Oncol. 2008;26(May 20 suppl):abstr 2010b.
-
Cloughesy TF, Prados MD, Wen PY, et al. A phase II, randomized, non-comparative clinical trial of the effect of bevacizumab (BV) alone or in combination with irinotecan (CPT) on 6-month progression free survival (PFS6) in recurrent, treatment-refractory glioblastoma (GBM). J Clin Oncol. 2008;26(May 20 suppl):abstr 2010b.
-
-
-
-
30
-
-
0035866771
-
Inhibition of vascular endothelial growth factor receptor signaling leads to reversal of tumor resistance to radiotherapy
-
Geng L, Donnelly E, McMahon G, et al. Inhibition of vascular endothelial growth factor receptor signaling leads to reversal of tumor resistance to radiotherapy. Cancer Res. 2001;61(6):2413-2419.
-
(2001)
Cancer Res
, vol.61
, Issue.6
, pp. 2413-2419
-
-
Geng, L.1
Donnelly, E.2
McMahon, G.3
-
31
-
-
0035132923
-
Vascular endothelial growth factor receptor-2-blocking antibody potentiates radiation-induced long-term control of human tumor xenografts
-
Kozin SV, Boucher Y, Hicklin DJ, Bohlen P, Jain RK, Suit HD. Vascular endothelial growth factor receptor-2-blocking antibody potentiates radiation-induced long-term control of human tumor xenografts. Cancer Res. 2001;61(1):39-44.
-
(2001)
Cancer Res
, vol.61
, Issue.1
, pp. 39-44
-
-
Kozin, S.V.1
Boucher, Y.2
Hicklin, D.J.3
Bohlen, P.4
Jain, R.K.5
Suit, H.D.6
-
32
-
-
45249097586
-
Phase II pilot study of bevacizumab in combination with temozolomide and regional radiation therapy for up-front treatment of patients with newly diagnosed glioblastoma multiforme: Interim analysis of safety and tolerability
-
Lai A, Filka E, McGibbon B, Nghiemphu PL, et al. Phase II pilot study of bevacizumab in combination with temozolomide and regional radiation therapy for up-front treatment of patients with newly diagnosed glioblastoma multiforme: interim analysis of safety and tolerability. Int J Radiat Oncol Biol Phys. 2008;71(5):1372-1380.
-
(2008)
Int J Radiat Oncol Biol Phys
, vol.71
, Issue.5
, pp. 1372-1380
-
-
Lai, A.1
Filka, E.2
McGibbon, B.3
Nghiemphu, P.L.4
-
33
-
-
33846149645
-
AZD2171, a Pan-VEGF Receptor Tyrosine Kinase Inhibitor, Normalizes Tumor Vasculature and Alleviates Edema in Glioblastoma Patients
-
Batchelor TT, Sorensen AG, di Tomaso E, et al. AZD2171, a Pan-VEGF Receptor Tyrosine Kinase Inhibitor, Normalizes Tumor Vasculature and Alleviates Edema in Glioblastoma Patients. Cancer Cell. 2007;11(1):83-95.
-
(2007)
Cancer Cell
, vol.11
, Issue.1
, pp. 83-95
-
-
Batchelor, T.T.1
Sorensen, A.G.2
di Tomaso, E.3
-
34
-
-
0037401890
-
R1R2 suppresses choroidal neovascularization and VEGF-induced breakdown of the blood-retinal barrier
-
R1R2 suppresses choroidal neovascularization and VEGF-induced breakdown of the blood-retinal barrier. J Cell Physiol. 2003;195:241-248.
-
(2003)
J Cell Physiol
, vol.195
, pp. 241-248
-
-
Saishin, Y.1
Saishin YTakahasi, K.2
-
35
-
-
7444261960
-
Use of soluble recombinant decoy receptor vascular endothelial growth factor trap (VEGF Trap) to inhibit vascular endothelial growth factor activity
-
Konner J, Dupont J. Use of soluble recombinant decoy receptor vascular endothelial growth factor trap (VEGF Trap) to inhibit vascular endothelial growth factor activity. Clin Colorectal Cancer. 2004;4 Suppl 2:S81-85.
-
(2004)
Clin Colorectal Cancer
, vol.4
, Issue.SUPPL. 2
-
-
Konner, J.1
Dupont, J.2
-
36
-
-
0037143764
-
VEGF-Trap: A VEGF blocker with potent antitumor effects
-
Holash J, Davis S, Papadopoulos N, et al. VEGF-Trap: a VEGF blocker with potent antitumor effects. Proc Natl Acad Sci U S A, 2002;99(17):11393-11398.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, Issue.17
, pp. 11393-11398
-
-
Holash, J.1
Davis, S.2
Papadopoulos, N.3
-
37
-
-
33947531672
-
VEGF trap in combination with radiotherapy improves tumor control in u87 glioblastoma
-
Wachsberger PR, Burd R, Cardi C, et al. VEGF trap in combination with radiotherapy improves tumor control in u87 glioblastoma. Int J Radiat Oncol Biol Phys. 2007;67(5):1526-1537.
-
(2007)
Int J Radiat Oncol Biol Phys
, vol.67
, Issue.5
, pp. 1526-1537
-
-
Wachsberger, P.R.1
Burd, R.2
Cardi, C.3
-
38
-
-
55749102152
-
Phase II single arm trial of aflibercept in patients with recurrent temozolomide-resistant glioblastoma: NABTC 0601
-
May 20 suppl, abstr 2020
-
De Groot JF, Wen PY, Lamborn K, et al. Phase II single arm trial of aflibercept in patients with recurrent temozolomide-resistant glioblastoma: NABTC 0601. J Clin Oncol. 2008;26(May 20 suppl): abstr 2020.
-
(2008)
J Clin Oncol
, pp. 26
-
-
De Groot, J.F.1
Wen, P.Y.2
Lamborn, K.3
-
39
-
-
3543028023
-
PTK787/ZK222584, an inhibitor of vascular endothelial growth factor receptor tyrosine kinases, decreases glioma growth and vascularization
-
discussion 432
-
Goldbrunner RH, Bendszus M, Wood J, Kiderlen M, Sasaki M, Tonn JC. PTK787/ZK222584, an inhibitor of vascular endothelial growth factor receptor tyrosine kinases, decreases glioma growth and vascularization. Neurosurgery. 2004;55(2):426-432; discussion 432.
-
(2004)
Neurosurgery
, vol.55
, Issue.2
, pp. 426-432
-
-
Goldbrunner, R.H.1
Bendszus, M.2
Wood, J.3
Kiderlen, M.4
Sasaki, M.5
Tonn, J.C.6
-
40
-
-
65349187463
-
-
Yung WKA, Friedman H, Conrad C, et al. A phase I trial of single-agent PTK 787/ZK 222584 (PTK/ZK), an oral VEGFR tyrosine kinase inhibitor, in patients with recurrent glioblastoma multiforme. Proceedings of the American Society of Clinical Oncology Meeting. Chicago, USA. 2003. Abstract 395.
-
Yung WKA, Friedman H, Conrad C, et al. A phase I trial of single-agent PTK 787/ZK 222584 (PTK/ZK), an oral VEGFR tyrosine kinase inhibitor, in patients with recurrent glioblastoma multiforme. Proceedings of the American Society of Clinical Oncology Meeting. Chicago, USA. 2003. Abstract 395.
-
-
-
-
41
-
-
65349191600
-
-
Conrad C, Friedman H, Reardon D. A Phase I/II trial of single-agent PTK787/ZK222584 (PTK/ZK), a novel, oral angiogenesis inhibitor, in patients with recurrent glioblastoma multiforme (GBM). Proceedings of the American Society of Clinical Oncology Meeting. New Orleans, USA. 2004. Abstract 1512.
-
Conrad C, Friedman H, Reardon D. A Phase I/II trial of single-agent PTK787/ZK222584 (PTK/ZK), a novel, oral angiogenesis inhibitor, in patients with recurrent glioblastoma multiforme (GBM). Proceedings of the American Society of Clinical Oncology Meeting. New Orleans, USA. 2004. Abstract 1512.
-
-
-
-
42
-
-
65349098606
-
-
Reardon D, Friedman H, Yung WKA, et al. A phase I/II trial of PTK787/ZK 222584 (PTK/ZK), a novel, oral angiogenesis inhibitor, in combination with either temozolomide or lomustine for patients with recurrent glioblastoma multiforme (GBM). Proceedings of the American Society of Clinical Oncology Meeting. New Orleans, USA. 2004. Abstract 1513.
-
Reardon D, Friedman H, Yung WKA, et al. A phase I/II trial of PTK787/ZK 222584 (PTK/ZK), a novel, oral angiogenesis inhibitor, in combination with either temozolomide or lomustine for patients with recurrent glioblastoma multiforme (GBM). Proceedings of the American Society of Clinical Oncology Meeting. New Orleans, USA. 2004. Abstract 1513.
-
-
-
-
43
-
-
0025790916
-
Genes for epidermal growth factor receptor, transforming growth factor alpha, and epidermal growth factor and their expression in human gliomas in vivo
-
Ekstrand AJ, James CD, Cavenee WK, Seliger B, Pettersson RF, Collins VP. Genes for epidermal growth factor receptor, transforming growth factor alpha, and epidermal growth factor and their expression in human gliomas in vivo. Cancer Res. 1991;51(8):2164-2172.
-
(1991)
Cancer Res
, vol.51
, Issue.8
, pp. 2164-2172
-
-
Ekstrand, A.J.1
James, C.D.2
Cavenee, W.K.3
Seliger, B.4
Pettersson, R.F.5
Collins, V.P.6
-
45
-
-
1842500007
-
Phase II trial of gefitinib in recurrent glioblastoma
-
Rich JN, Reardon DA, Peery T, et al. Phase II trial of gefitinib in recurrent glioblastoma. J Clin Oncol. 2004;22(1):133-142.
-
(2004)
J Clin Oncol
, vol.22
, Issue.1
, pp. 133-142
-
-
Rich, J.N.1
Reardon, D.A.2
Peery, T.3
-
48
-
-
31544474851
-
Phase 1 study of erlotinib HCl alone and combined with temozolomide in patients with stable or recurrent malignant glioma
-
Prados MD, Lamborn KR, Chang S, et al. Phase 1 study of erlotinib HCl alone and combined with temozolomide in patients with stable or recurrent malignant glioma. Neuro Oncol. 2006;8(1):67-78.
-
(2006)
Neuro Oncol
, vol.8
, Issue.1
, pp. 67-78
-
-
Prados, M.D.1
Lamborn, K.R.2
Chang, S.3
-
49
-
-
65349170767
-
-
New Orleans, USA, Abstract 1558
-
Vogelbaum MA, Peereboom D, Stevens G, Barnett G, Brewer C. Phase II trial of the EGFR tyrosine kinase inhibitor erlotinib for single agent therapy of recurrent glioblastoma mutliforme: Interim results. Proceedings of the American Society of Clinical Oncology Meeting. New Orleans, USA. 2004. Abstract 1558.
-
(2004)
Phase II trial of the EGFR tyrosine kinase inhibitor erlotinib for single agent therapy of recurrent glioblastoma mutliforme: Interim results. Proceedings of the American Society of Clinical Oncology Meeting
-
-
Vogelbaum, M.A.1
Peereboom, D.2
Stevens, G.3
Barnett, G.4
Brewer, C.5
-
50
-
-
16844384784
-
A phase II trial of erlotinib (OSI-774) in patients (pts) with recurrent malignant gliomas (MG) not on EIAEDs
-
New Orleans, USA, Abstract 1502
-
Raizer JJ, Abrey LE, Wen P, et al. A phase II trial of erlotinib (OSI-774) in patients (pts) with recurrent malignant gliomas (MG) not on EIAEDs. Proceedings of the American Society of Clinical Oncology Meeting. New Orleans, USA. 2004. Abstract 1502.
-
(2004)
Proceedings of the American Society of Clinical Oncology Meeting
-
-
Raizer, J.J.1
Abrey, L.E.2
Wen, P.3
-
51
-
-
27744606737
-
Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors
-
Mellinghoff IK, Wang MY, Vivanco I, et al. Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors. N Engl J Med. 2005;353(19):2012-2024.
-
(2005)
N Engl J Med
, vol.353
, Issue.19
, pp. 2012-2024
-
-
Mellinghoff, I.K.1
Wang, M.Y.2
Vivanco, I.3
-
52
-
-
21444450373
-
Epidermal growth factor receptor, protein kinase B/Akt, and glioma response to erlotinib
-
Haas-Kogan DA, Prados MD, Tihan T, et al. Epidermal growth factor receptor, protein kinase B/Akt, and glioma response to erlotinib. J Natl Cancer Inst. 2005;97(12):880-887.
-
(2005)
J Natl Cancer Inst
, vol.97
, Issue.12
, pp. 880-887
-
-
Haas-Kogan, D.A.1
Prados, M.D.2
Tihan, T.3
-
53
-
-
0034665138
-
Intracranial inhibition of plateletderived growth factor-mediated glioblastoma cell growth by an orally active kinase inhibitor of the 2-phenylaminopyrimidine class
-
Kilic T, Alberta JA, Zdunek PR, et al. Intracranial inhibition of plateletderived growth factor-mediated glioblastoma cell growth by an orally active kinase inhibitor of the 2-phenylaminopyrimidine class. Cancer Res. 2000;60(18):5143-5150.
-
(2000)
Cancer Res
, vol.60
, Issue.18
, pp. 5143-5150
-
-
Kilic, T.1
Alberta, J.A.2
Zdunek, P.R.3
-
54
-
-
29244438974
-
STI571 (Gleevec) improves tumor growth delay and survival in irradiated mouse models of glioblastoma
-
Geng L, Shinohara ET, Kim D, et al. STI571 (Gleevec) improves tumor growth delay and survival in irradiated mouse models of glioblastoma. Int J Radiat Oncol Biol Phys. 2006;64(1):263-271.
-
(2006)
Int J Radiat Oncol Biol Phys
, vol.64
, Issue.1
, pp. 263-271
-
-
Geng, L.1
Shinohara, E.T.2
Kim, D.3
-
55
-
-
33748376520
-
Phase I/II study of imatinib mesylate for recurrent malignant gliomas: North American Brain Tumor Consortium Study 99-08
-
Wen PY, Yung WK, Lamborn KR, et al. Phase I/II study of imatinib mesylate for recurrent malignant gliomas: North American Brain Tumor Consortium Study 99-08. Clin Cancer Res. 2006;12(16):4899-4907.
-
(2006)
Clin Cancer Res
, vol.12
, Issue.16
, pp. 4899-4907
-
-
Wen, P.Y.1
Yung, W.K.2
Lamborn, K.R.3
-
56
-
-
26444621412
-
Imatinib and hydroxyurea in pretreated progressive glioblastoma multiforme: A patient series
-
Dresemann G. Imatinib and hydroxyurea in pretreated progressive glioblastoma multiforme: a patient series. Ann Oncol. 2005;16(10):1702-1708.
-
(2005)
Ann Oncol
, vol.16
, Issue.10
, pp. 1702-1708
-
-
Dresemann, G.1
-
57
-
-
33644830094
-
Phase II study of imatinib mesylate plus hydroxyurea in adults with recurrent glioblastoma multiforme
-
Reardon DA, Egorin MJ, Quinn JA, et al. Phase II study of imatinib mesylate plus hydroxyurea in adults with recurrent glioblastoma multiforme. J Clin Oncol. 2005;23(36):9359-9368.
-
(2005)
J Clin Oncol
, vol.23
, Issue.36
, pp. 9359-9368
-
-
Reardon, D.A.1
Egorin, M.J.2
Quinn, J.A.3
-
58
-
-
34247476830
-
Phase II study of imatinib mesylate and hydroxyurea for recurrent grade III malignant gliomas
-
Desjardins A, Quinn JA, Vredenburgh JJ, et al. Phase II study of imatinib mesylate and hydroxyurea for recurrent grade III malignant gliomas. J Neurooncol. 2007;83(1):53-60.
-
(2007)
J Neurooncol
, vol.83
, Issue.1
, pp. 53-60
-
-
Desjardins, A.1
Quinn, J.A.2
Vredenburgh, J.J.3
-
59
-
-
8844252330
-
Mutation analysis of the Ras pathway genes NRAS, HRAS, KRAS and BRAF in glioblastomas
-
Knobbe CB, Reifenberger J, Reifenberger G. Mutation analysis of the Ras pathway genes NRAS, HRAS, KRAS and BRAF in glioblastomas. Acta Neuropathol (Berl). 2004;108:467-470.
-
(2004)
Acta Neuropathol (Berl)
, vol.108
, pp. 467-470
-
-
Knobbe, C.B.1
Reifenberger, J.2
Reifenberger, G.3
-
60
-
-
33745307617
-
-
Shaw RJ, Cantley LC. Ras, PI(3)K and mTOR signalling controls tumour cell growth. Nature. 2006;441:424-430.
-
Shaw RJ, Cantley LC. Ras, PI(3)K and mTOR signalling controls tumour cell growth. Nature. 2006;441:424-430.
-
-
-
-
61
-
-
33747058029
-
Phase II trial of tipifarnib in patients with recurrent malignant glioma either receiving or not receiving enzyme-inducing antiepileptic drugs: A North American Brain Tumor Consortium Study
-
Cloughesy TF, Wen PY, Robins HI, et al. Phase II trial of tipifarnib in patients with recurrent malignant glioma either receiving or not receiving enzyme-inducing antiepileptic drugs: a North American Brain Tumor Consortium Study. J Clin Oncol. 2006;24(22):3651-3656.
-
(2006)
J Clin Oncol
, vol.24
, Issue.22
, pp. 3651-3656
-
-
Cloughesy, T.F.1
Wen, P.Y.2
Robins, H.I.3
-
62
-
-
33847354832
-
A phase I study of temozolomide (TMZ) and the farnesyltransferase inhibitor (FTI), lonafarnib (Sarazar, SCH66336) in recurrent glioblastoma
-
Atlanta, USA, Abstract 1556
-
Gilbert MR, Gaupp P, Liu V, et al. A phase I study of temozolomide (TMZ) and the farnesyltransferase inhibitor (FTI), lonafarnib (Sarazar, SCH66336) in recurrent glioblastoma. Proceedings of the American Society of Clinical Oncology Meeting. Atlanta, USA. 2006. Abstract 1556.
-
(2006)
Proceedings of the American Society of Clinical Oncology Meeting
-
-
Gilbert, M.R.1
Gaupp, P.2
Liu, V.3
-
63
-
-
33749016521
-
AAL881, a novel small molecule inhibitor of RAF and vascular endothelial growth factor receptor activities, blocks the growth of malignant glioma
-
Sathornsumetee S, Hjelmeland AB, Keir ST, et al. AAL881, a novel small molecule inhibitor of RAF and vascular endothelial growth factor receptor activities, blocks the growth of malignant glioma. Cancer Res. 2006;66(17):8722-8730.
-
(2006)
Cancer Res
, vol.66
, Issue.17
, pp. 8722-8730
-
-
Sathornsumetee, S.1
Hjelmeland, A.B.2
Keir, S.T.3
-
64
-
-
3042823868
-
The prognostic signifi cance of phosphatidylinositol 3-kinase pathway activation in human gliomas
-
Chakravarti A, Zhai G, Suzuki Y, et al. The prognostic signifi cance of phosphatidylinositol 3-kinase pathway activation in human gliomas. J Clin Oncol. 2004;22:1926-1933.
-
(2004)
J Clin Oncol
, vol.22
, pp. 1926-1933
-
-
Chakravarti, A.1
Zhai, G.2
Suzuki, Y.3
-
65
-
-
23844457178
-
Perifosine inhibits multiple signaling pathways in glial progenitors and cooperates with temozolomide to arrest cell proliferation in gliomas in vivo
-
Momota H, Nerio E, Holland EC. Perifosine inhibits multiple signaling pathways in glial progenitors and cooperates with temozolomide to arrest cell proliferation in gliomas in vivo. Cancer Res. 2005;65:7429-7435.
-
(2005)
Cancer Res
, vol.65
, pp. 7429-7435
-
-
Momota, H.1
Nerio, E.2
Holland, E.C.3
-
66
-
-
65349090491
-
Clinical and molecular-metabolic phase II trial of perifosine for recurrent/ progressive malignant glioma
-
Abstract MA-15
-
Lassman A, Holland E, DeAngelis L, Panageas K, Abrey L. Clinical and molecular-metabolic phase II trial of perifosine for recurrent/ progressive malignant glioma. Neuro Oncol. 2007;9(4):467-602, Abstract MA-15.
-
(2007)
Neuro Oncol
, vol.9
, Issue.4
, pp. 467-602
-
-
Lassman, A.1
Holland, E.2
DeAngelis, L.3
Panageas, K.4
Abrey, L.5
-
67
-
-
21044431575
-
Phase II study of CCI-779 in patients with recurrent glioblastoma multiforme
-
Chang SM, Wen P, Cloughesy T, et al. Phase II study of CCI-779 in patients with recurrent glioblastoma multiforme. Invest New Drugs. 2005;23:357-361.
-
(2005)
Invest New Drugs
, vol.23
, pp. 357-361
-
-
Chang, S.M.1
Wen, P.2
Cloughesy, T.3
-
68
-
-
23944453425
-
Phase II trial of temsirolimus (CCI-779) in recurrent glioblastoma multiforme: A North Central Cancer Treatment Group Study
-
Galanis E, Buckner JC, Maurer MJ, et al. Phase II trial of temsirolimus (CCI-779) in recurrent glioblastoma multiforme: a North Central Cancer Treatment Group Study. J Clin Oncol. 2005;23:5294-5304.
-
(2005)
J Clin Oncol
, vol.23
, pp. 5294-5304
-
-
Galanis, E.1
Buckner, J.C.2
Maurer, M.J.3
-
69
-
-
33746104821
-
Will kinase inhibitors have a dark side?
-
Sawyers CL. Will kinase inhibitors have a dark side? N Engl J Med. 2006;355:313-315.
-
(2006)
N Engl J Med
, vol.355
, pp. 313-315
-
-
Sawyers, C.L.1
-
70
-
-
33646382364
-
A dual PI3 kinase/mTOR inhibitor reveals emergent efficacy in glioma
-
Fan QW, Knight ZA, Goldenberg DD, et al. A dual PI3 kinase/mTOR inhibitor reveals emergent efficacy in glioma. Cancer Cell. 2006;9:341-349.
-
(2006)
Cancer Cell
, vol.9
, pp. 341-349
-
-
Fan, Q.W.1
Knight, Z.A.2
Goldenberg, D.D.3
-
71
-
-
10844232874
-
Agents with selective estrogen receptor (ER) modulator activity induce apoptosis in vitro and in vivo in ER-negative glioma cells
-
Hui AM, Zhang W, Chen W, et al. Agents with selective estrogen receptor (ER) modulator activity induce apoptosis in vitro and in vivo in ER-negative glioma cells. Cancer Res. 2004;64(24):9115-9123.
-
(2004)
Cancer Res
, vol.64
, Issue.24
, pp. 9115-9123
-
-
Hui, A.M.1
Zhang, W.2
Chen, W.3
-
72
-
-
0032975369
-
Procarbazine and high-dose tamoxifen as a second-line regimen in recurrent high-grade gliomas: A phase II study
-
Brandes AA, Ermani M, Turazzi S, et al. Procarbazine and high-dose tamoxifen as a second-line regimen in recurrent high-grade gliomas: a phase II study. J Clin Oncol. 1997;17(2):645-650.
-
(1997)
J Clin Oncol
, vol.17
, Issue.2
, pp. 645-650
-
-
Brandes, A.A.1
Ermani, M.2
Turazzi, S.3
-
73
-
-
4444222498
-
Phase II study of concurrent continuous Temozolomide (TMZ) and Tamoxifen (TMX) for recurrent malignant astrocytic gliomas
-
Spence AM, Peterson RA, Scharnhorst JD, Silbergeld DL, Rostomily RC. Phase II study of concurrent continuous Temozolomide (TMZ) and Tamoxifen (TMX) for recurrent malignant astrocytic gliomas. J Neurooncol. 2004:70(1):91-95.
-
(2004)
J Neurooncol
, vol.70
, Issue.1
, pp. 91-95
-
-
Spence, A.M.1
Peterson, R.A.2
Scharnhorst, J.D.3
Silbergeld, D.L.4
Rostomily, R.C.5
-
74
-
-
31544471131
-
Phase 2 trial of radiation plus high-dose tamoxifen for glioblastoma multiforme: RTOG protocol BR-0021
-
Robins HI, Won M, Seiferheld WF, et al. Phase 2 trial of radiation plus high-dose tamoxifen for glioblastoma multiforme: RTOG protocol BR-0021. Neuro Oncol. 2006;8(1):47-52.
-
(2006)
Neuro Oncol
, vol.8
, Issue.1
, pp. 47-52
-
-
Robins, H.I.1
Won, M.2
Seiferheld, W.F.3
-
75
-
-
33745773066
-
A phase II study of carboplatin and chronic high-dose tamoxifen in patients with recurrent malignant glioma
-
Tang P, Roldan G, Brasher PM, et al. A phase II study of carboplatin and chronic high-dose tamoxifen in patients with recurrent malignant glioma. J Neuro Oncol. 2006;78(3), 311-316.
-
(2006)
J Neuro Oncol
, vol.78
, Issue.3
, pp. 311-316
-
-
Tang, P.1
Roldan, G.2
Brasher, P.M.3
-
76
-
-
0034534262
-
Surgery, tamoxifen, carboplatin, and radiotherapy in the treatment of newly diagnosed glioblastoma patients
-
Puchner MJ, Herrmann HD, Berger J, Cristante L. Surgery, tamoxifen, carboplatin, and radiotherapy in the treatment of newly diagnosed glioblastoma patients. J Neurooncol. 2000;49(2):147-155.
-
(2000)
J Neurooncol
, vol.49
, Issue.2
, pp. 147-155
-
-
Puchner, M.J.1
Herrmann, H.D.2
Berger, J.3
Cristante, L.4
-
77
-
-
0031950726
-
High dose oral tamoxifen and subcutaneous interferon alpha-2a for recurrent glioma
-
Chang SM, Barker FG 2nd, Huhn SL, et al. High dose oral tamoxifen and subcutaneous interferon alpha-2a for recurrent glioma. J Neurooncol. 1998;37(2):169-176.
-
(1998)
J Neurooncol
, vol.37
, Issue.2
, pp. 169-176
-
-
Chang, S.M.1
Barker 2nd, F.G.2
Huhn, S.L.3
-
78
-
-
0027469702
-
Clinical and radiographic response in a minority of patients with recurrent malignant gliomas treated with high-dose tamoxifen
-
discussion 489-490
-
Couldwell WT, Weiss MH, DeGiorgio CM, et al. Clinical and radiographic response in a minority of patients with recurrent malignant gliomas treated with high-dose tamoxifen. Neurosurgery. 1993;32(3):485-489; discussion 489-490.
-
(1993)
Neurosurgery
, vol.32
, Issue.3
, pp. 485-489
-
-
Couldwell, W.T.1
Weiss, M.H.2
DeGiorgio, C.M.3
-
79
-
-
23844521568
-
The protein kinase Cbeta-selective inhibitor, Enzastaurin (LY317615.HC1), suppresses signaling through the AKT pathway, induces apoptosis, and suppresses growth of human colon cancer and glioblastoma xenografts
-
Graff JR, McNulty AM, Hanna KR, et al. The protein kinase Cbeta-selective inhibitor, Enzastaurin (LY317615.HC1), suppresses signaling through the AKT pathway, induces apoptosis, and suppresses growth of human colon cancer and glioblastoma xenografts. Cancer Res. 2005;65(16):7462-7469.
-
(2005)
Cancer Res
, vol.65
, Issue.16
, pp. 7462-7469
-
-
Graff, J.R.1
McNulty, A.M.2
Hanna, K.R.3
-
80
-
-
33646555670
-
Results from phase II trial of enzastaurin (LY317615) in patients with recurrent high grade gliomas
-
Orlando, USA, Abstract 1504
-
Fine HA, Kim L, Royce C, et al. Results from phase II trial of enzastaurin (LY317615) in patients with recurrent high grade gliomas Proceedings of the American Society of Clinical Oncology Meeting. Orlando, USA. 2004. Abstract 1504.
-
(2004)
Proceedings of the American Society of Clinical Oncology Meeting
-
-
Fine, H.A.1
Kim, L.2
Royce, C.3
-
81
-
-
65349196779
-
-
Fine HA, Puduvalli VK, Chamberlain MC, et al. Enzastaurin (ENZ) versus lomustine (CCNU) in the treatment of recurrent, intracranial glioblastoma multiforme (GBM): A phase III study. J Clin Oncol. 2008;26(May 20 suppl):abstr 2005.
-
Fine HA, Puduvalli VK, Chamberlain MC, et al. Enzastaurin (ENZ) versus lomustine (CCNU) in the treatment of recurrent, intracranial glioblastoma multiforme (GBM): A phase III study. J Clin Oncol. 2008;26(May 20 suppl):abstr 2005.
-
-
-
-
82
-
-
17844367105
-
Alpha(v)beta3 and alpha(v)beta5integrin expression in glioma periphery
-
discussion 390
-
Bello L, Francolini M, Marthyn P, Zhang J, Carroll RS, Nikas DC, et al. Alpha(v)beta3 and alpha(v)beta5integrin expression in glioma periphery. Nieurosurgery 2001;49(2):380-389(discussion 390).
-
(2001)
Nieurosurgery
, vol.49
, Issue.2
, pp. 380-389
-
-
Bello, L.1
Francolini, M.2
Marthyn, P.3
Zhang, J.4
Carroll, R.S.5
Nikas, D.C.6
-
83
-
-
0028911765
-
Comparison of cell adhesion molecule expression between glioblastoma multiforme and autologous normal brain tissue
-
Gingras MC, Roussel E, Bruner JM, Branch CD, Moser RP. Comparison of cell adhesion molecule expression between glioblastoma multiforme and autologous normal brain tissue. J Neuroimmunol. 1995;57(1-2):143-153.
-
(1995)
J Neuroimmunol
, vol.57
, Issue.1-2
, pp. 143-153
-
-
Gingras, M.C.1
Roussel, E.2
Bruner, J.M.3
Branch, C.D.4
Moser, R.P.5
-
84
-
-
0029846478
-
Expression of integrin alpha v beta 3 in small blood vessels of glioblastoma tumors
-
Gladson CL. Expression of integrin alpha v beta 3 in small blood vessels of glioblastoma tumors. J Neuropathol Exp Neurol. 1996;55(11):1143-1149.
-
(1996)
J Neuropathol Exp Neurol
, vol.55
, Issue.11
, pp. 1143-1149
-
-
Gladson, C.L.1
-
85
-
-
33645551144
-
Integrins: Molecular targets in cancer therapy
-
Tucker GC: Integrins: molecular targets in cancer therapy. Curr Oncol Rep. 2006;8(2):96-103.
-
(2006)
Curr Oncol Rep
, vol.8
, Issue.2
, pp. 96-103
-
-
Tucker, G.C.1
-
86
-
-
34249087162
-
Phase I and correlative biology study of cilengitide in patients with recurrent malignant glioma
-
Nabors LB, Mikkelsen T, Rosenfeld SS, Hochberg F, Akella NS, Fisher JD, et al. Phase I and correlative biology study of cilengitide in patients with recurrent malignant glioma. J Clin Oncol. 2007;25(13):1651-1657.
-
(2007)
J Clin Oncol
, vol.25
, Issue.13
, pp. 1651-1657
-
-
Nabors, L.B.1
Mikkelsen, T.2
Rosenfeld, S.S.3
Hochberg, F.4
Akella, N.S.5
Fisher, J.D.6
-
87
-
-
65349096575
-
-
Reardon DA, Fink K, Nabors LB, Cloughesy T, Plotkin S, Schiff D, et al. Phase IIa trial of cilengitide (EMD121974) single-agent therapy in patients (pts) with recurrent glioblastoma (GBM): EMD 121974-009. In 43rd Annual Meeting of American Society of Clinical Oncology. Edited by Grunberg SM. Chicago, IL: Lisa Greaves;2007:75s.
-
Reardon DA, Fink K, Nabors LB, Cloughesy T, Plotkin S, Schiff D, et al. Phase IIa trial of cilengitide (EMD121974) single-agent therapy in patients (pts) with recurrent glioblastoma (GBM): EMD 121974-009. In 43rd Annual Meeting of American Society of Clinical Oncology. Edited by Grunberg SM. Chicago, IL: Lisa Greaves;2007:75s.
-
-
-
-
88
-
-
65349184319
-
-
Stupp R, Goldbrunner R, Neyns B, et al. Phase I/IIa trial of cilengitide (EMD121974) and temozolomide with concomitant radiotherapy, followed by temozolomide and cilengitide maintenance therapy in patients (pts) with newly diagnosed glioblastoma (GBM). J Clin Oncol, 2007 ASCO Annual Meeting Proceedings 2007;25(Pt 1):No. 18S (June 20 Supplement).
-
Stupp R, Goldbrunner R, Neyns B, et al. Phase I/IIa trial of cilengitide (EMD121974) and temozolomide with concomitant radiotherapy, followed by temozolomide and cilengitide maintenance therapy in patients (pts) with newly diagnosed glioblastoma (GBM). J Clin Oncol, 2007 ASCO Annual Meeting Proceedings 2007;25(Pt 1):No. 18S (June 20 Supplement).
-
-
-
-
89
-
-
13944269599
-
Combination therapy of inhibitors of epidermal growth factor receptor/vascular endothelial growth factor receptor 2 (AEE788) and the mammalian target of rapamycin (RAD001) offers improved glioblastoma tumor growth inhibition
-
Goudar RK, Shi Q, Hjelmeland MD, et al. Combination therapy of inhibitors of epidermal growth factor receptor/vascular endothelial growth factor receptor 2 (AEE788) and the mammalian target of rapamycin (RAD001) offers improved glioblastoma tumor growth inhibition. Mol Cancer Ther. 2005;4(1):101-112.
-
(2005)
Mol Cancer Ther
, vol.4
, Issue.1
, pp. 101-112
-
-
Goudar, R.K.1
Shi, Q.2
Hjelmeland, M.D.3
-
90
-
-
28144450936
-
ZD6474, a novel tyrosine kinase inhibitor of vascular endothelial growth factor receptor and epidermal growth factor receptor, inhibits tumor growth of multiple nervous system tumors
-
Rich JN, Sathornsumetee S, Keir ST, et al. ZD6474, a novel tyrosine kinase inhibitor of vascular endothelial growth factor receptor and epidermal growth factor receptor, inhibits tumor growth of multiple nervous system tumors. Clin Cancer Res. 2005;11(22):8145-8157.
-
(2005)
Clin Cancer Res
, vol.11
, Issue.22
, pp. 8145-8157
-
-
Rich, J.N.1
Sathornsumetee, S.2
Keir, S.T.3
-
91
-
-
0041672482
-
SU11248 maintenance therapy prevents tumor regrowth after fractionated irradiation of murine tumor models
-
Schueneman AJ, Himmelfarb E, Geng L, et al. SU11248 maintenance therapy prevents tumor regrowth after fractionated irradiation of murine tumor models. Cancer Res. 2003;63(14):4009-4016.
-
(2003)
Cancer Res
, vol.63
, Issue.14
, pp. 4009-4016
-
-
Schueneman, A.J.1
Himmelfarb, E.2
Geng, L.3
-
92
-
-
65349105205
-
An update on phase I study of dose-escalating imatinib mesylate plus standard-dosed temozolomide for the treatment of patients with malignant glioma
-
Atlanta, USA, Abstract 1560
-
Sathornsumetee S, Reardon DA, Quinn JA, et al. An update on phase I study of dose-escalating imatinib mesylate plus standard-dosed temozolomide for the treatment of patients with malignant glioma. Proceedings of the American Society of Clinical Oncology Meeting. Atlanta, USA. 2006. Abstract 1560.
-
(2006)
Proceedings of the American Society of Clinical Oncology Meeting
-
-
Sathornsumetee, S.1
Reardon, D.A.2
Quinn, J.A.3
-
93
-
-
5444255629
-
Phase I study of ZD1839 plus temozolomide in patients with malignant glioma. A study of the North American Brain Tumor Consortium
-
New Orleans, USA, Abstract 1504
-
Prados M, Yung W, Wen P, et al. Phase I study of ZD1839 plus temozolomide in patients with malignant glioma. A study of the North American Brain Tumor Consortium. Proceedings of the American Society of Clinical Oncology Meeting. New Orleans, USA. 2004. Abstract 1504.
-
(2004)
Proceedings of the American Society of Clinical Oncology Meeting
-
-
Prados, M.1
Yung, W.2
Wen, P.3
-
94
-
-
33745183568
-
Phase I trial of erlotinib with radiation therapy in patients with glioblastoma multiforme: Results of North Central Cancer Treatment Group protocol N0177
-
Krishnan S, Brown PD, Ballman KV, et al. Phase I trial of erlotinib with radiation therapy in patients with glioblastoma multiforme: results of North Central Cancer Treatment Group protocol N0177. Int J Radiat Oncol Biol Phys. 2006;65(4):1192-1199.
-
(2006)
Int J Radiat Oncol Biol Phys
, vol.65
, Issue.4
, pp. 1192-1199
-
-
Krishnan, S.1
Brown, P.D.2
Ballman, K.V.3
-
95
-
-
0036643779
-
Farnesyltransferase inhibitor, R115777, reverses the resistance of human glioma cell lines to ionizing radiation
-
Delmas C, Heliez C, Cohen-Jonathan E, et al. Farnesyltransferase inhibitor, R115777, reverses the resistance of human glioma cell lines to ionizing radiation. Int J Cancer. 2002;100(1):43-48.
-
(2002)
Int J Cancer
, vol.100
, Issue.1
, pp. 43-48
-
-
Delmas, C.1
Heliez, C.2
Cohen-Jonathan, E.3
-
96
-
-
0037115523
-
Inhibition of the mammalian target of rapamycin sensitizes U87 xenografts to fractionated radiation therapy
-
Eshleman JS, Carlson BL, Mladek AC, Kastner BD, Shide KL, Sarkaria JN. Inhibition of the mammalian target of rapamycin sensitizes U87 xenografts to fractionated radiation therapy. Cancer Res. 2002;62(24);7291-7297.
-
(2002)
Cancer Res
, vol.62
, Issue.24
, pp. 7291-7297
-
-
Eshleman, J.S.1
Carlson, B.L.2
Mladek, A.C.3
Kastner, B.D.4
Shide, K.L.5
Sarkaria, J.N.6
-
97
-
-
0026455838
-
Supratentorial malignant glioma: Patterns of recurrence and implications for external beam local treatment
-
Gaspar LE, Fisher BJ, Macdonald DR, et al. Supratentorial malignant glioma: patterns of recurrence and implications for external beam local treatment. Int J Radiat Oncol Biol Phys, 1992;24(1):55-57.
-
(1992)
Int J Radiat Oncol Biol Phys
, vol.24
, Issue.1
, pp. 55-57
-
-
Gaspar, L.E.1
Fisher, B.J.2
Macdonald, D.R.3
-
98
-
-
0018848780
-
Assumptions in the radiotherapy of glioblastoma
-
Hochberg FH, Pruitt A. Assumptions in the radiotherapy of glioblastoma. Neurology, 1980;30(9):907-911.
-
(1980)
Neurology
, vol.30
, Issue.9
, pp. 907-911
-
-
Hochberg, F.H.1
Pruitt, A.2
-
99
-
-
0028157552
-
Biodegradable polymers for controlled delivery of chemotherapy with and without radiation therapy in the monkey brain
-
Brem H, Tamargo RJ, Olivi A, et al. Biodegradable polymers for controlled delivery of chemotherapy with and without radiation therapy in the monkey brain. J Neurosurg. 1994;80(2);283-290.
-
(1994)
J Neurosurg
, vol.80
, Issue.2
, pp. 283-290
-
-
Brem, H.1
Tamargo, R.J.2
Olivi, A.3
-
100
-
-
0028917333
-
Placebo-controlled trial of safety and effi cacy of intraoperative controlled delivery by biodegradable polymers of chemotherapy for recurrent gliomas. The Polymer-brain Tumor Treatment Group
-
Brem H, Piantadosi S, Burger PC, et al. Placebo-controlled trial of safety and effi cacy of intraoperative controlled delivery by biodegradable polymers of chemotherapy for recurrent gliomas. The Polymer-brain Tumor Treatment Group. Lancet. 1995;345(8956);1008-1012.
-
(1995)
Lancet
, vol.345
, Issue.8956
, pp. 1008-1012
-
-
Brem, H.1
Piantadosi, S.2
Burger, P.C.3
-
101
-
-
0037384037
-
A phase 3 trial of local chemotherapy with biodegradable carmustine (BCNU) wafers (Gliadel wafers) in patients with primary malignant glioma
-
Westphal M, Hilt DC, Bortey E, et al. A phase 3 trial of local chemotherapy with biodegradable carmustine (BCNU) wafers (Gliadel wafers) in patients with primary malignant glioma. Neuro Oncol. 2003;5(2):79-88.
-
(2003)
Neuro Oncol
, vol.5
, Issue.2
, pp. 79-88
-
-
Westphal, M.1
Hilt, D.C.2
Bortey, E.3
-
102
-
-
4744345914
-
Randomized comparison of stereotactic radiosurgery followed by conventional radiotherapy with carmustine to conventional radiotherapy with carmustine for patients with glioblastoma multiforme: Report of Radiation Therapy Oncology Group 93-05 protocol
-
Souhami L, Seiferheld W, Brachman D, et al. Randomized comparison of stereotactic radiosurgery followed by conventional radiotherapy with carmustine to conventional radiotherapy with carmustine for patients with glioblastoma multiforme: report of Radiation Therapy Oncology Group 93-05 protocol. Int J Radiat Oncol Biol Phys. 2004;60(3):853-860.
-
(2004)
Int J Radiat Oncol Biol Phys
, vol.60
, Issue.3
, pp. 853-860
-
-
Souhami, L.1
Seiferheld, W.2
Brachman, D.3
-
103
-
-
0028891692
-
Comparison of stereotactic radiosurgery and brachytherapy in the treatment of recurrent glioblastoma multiforme
-
discussion 282-274
-
Shrieve DC, Alexander E 3rd, Wen PY, et al. Comparison of stereotactic radiosurgery and brachytherapy in the treatment of recurrent glioblastoma multiforme. Neurosurgery. 1995;36(2):275-282; discussion 282-274.
-
(1995)
Neurosurgery
, vol.36
, Issue.2
, pp. 275-282
-
-
Shrieve, D.C.1
Alexander 3rd, E.2
Wen, P.Y.3
-
104
-
-
0036705582
-
The Brain Tumor Cooperative Group NIH Trial 87-01: A randomized comparison of surgery, external radiotherapy, and carmustine versus surgery, interstitial radiotherapy boost, external radiation therapy, and carmustine
-
discussion 355-347
-
Selker RG, Shapiro WR, Burger P, et al. The Brain Tumor Cooperative Group NIH Trial 87-01: a randomized comparison of surgery, external radiotherapy, and carmustine versus surgery, interstitial radiotherapy boost, external radiation therapy, and carmustine. Neurosurgery. 2002;51(2):343-355; discussion 355-347.
-
(2002)
Neurosurgery
, vol.51
, Issue.2
, pp. 343-355
-
-
Selker, R.G.1
Shapiro, W.R.2
Burger, P.3
-
105
-
-
18744422314
-
Randomized study of brachytherapy in the initial management of patients with malignant astrocytoma
-
Laperriere NJ, Leung PM, McKenzie S, et al. Randomized study of brachytherapy in the initial management of patients with malignant astrocytoma. Int J Radiat Oncol Biol Phys. 1998;41(5):1005-1011.
-
(1998)
Int J Radiat Oncol Biol Phys
, vol.41
, Issue.5
, pp. 1005-1011
-
-
Laperriere, N.J.1
Leung, P.M.2
McKenzie, S.3
-
106
-
-
33645762754
-
GliaSite brachytherapy for treatment of recurrent malignant gliomas: A retrospective multi-institutional analysis
-
discussion 701-709
-
Gabayan AJ, Green SB, Sanan A, et al. GliaSite brachytherapy for treatment of recurrent malignant gliomas: a retrospective multi-institutional analysis. Neurosurgery. 2006;58(4):701-709; discussion 701-709.
-
(2006)
Neurosurgery
, vol.58
, Issue.4
, pp. 701-709
-
-
Gabayan, A.J.1
Green, S.B.2
Sanan, A.3
-
107
-
-
0034669697
-
Phase I trial results of iodine-131-labeled antitenascin monoclonal antibody 81C6 treatment of patients with newly diagnosed malignant gliomas
-
Cokgor I, Akabani G, Kuan CT, et al. Phase I trial results of iodine-131-labeled antitenascin monoclonal antibody 81C6 treatment of patients with newly diagnosed malignant gliomas. J Clin Oncol. 2000;18(22):3862-3872.
-
(2000)
J Clin Oncol
, vol.18
, Issue.22
, pp. 3862-3872
-
-
Cokgor, I.1
Akabani, G.2
Kuan, C.T.3
-
108
-
-
0036498790
-
Phase II trial of murine (131)I-labeled antitenascin monoclonal antibody 81C6 administered into surgically created resection cavities of patients with newly diagnosed malignant gliomas
-
Reardon DA, Akabani G, Coleman RE, et al. Phase II trial of murine (131)I-labeled antitenascin monoclonal antibody 81C6 administered into surgically created resection cavities of patients with newly diagnosed malignant gliomas. J Clin Oncol. 2002;20(5):1389-1397.
-
(2002)
J Clin Oncol
, vol.20
, Issue.5
, pp. 1389-1397
-
-
Reardon, D.A.1
Akabani, G.2
Coleman, R.E.3
-
109
-
-
33644833474
-
Salvage radioimmunotherapy with murine iodine-131-labeled antitenascin monoclonal antibody 81C6 for patients with recurrent primary and metastatic malignant brain tumors: Phase II study results
-
Reardon DA, Akabani G, Coleman RE, et al. Salvage radioimmunotherapy with murine iodine-131-labeled antitenascin monoclonal antibody 81C6 for patients with recurrent primary and metastatic malignant brain tumors: phase II study results. J Clin Oncol. 2006;24(1):115-122.
-
(2006)
J Clin Oncol
, vol.24
, Issue.1
, pp. 115-122
-
-
Reardon, D.A.1
Akabani, G.2
Coleman, R.E.3
-
110
-
-
0035291243
-
Delivery of molecular and cellular medicine to solid tumors
-
Jain RK. Delivery of molecular and cellular medicine to solid tumors. Adv Drug Deliv Rev. 2001;46(1-3):149-168.
-
(2001)
Adv Drug Deliv Rev
, vol.46
, Issue.1-3
, pp. 149-168
-
-
Jain, R.K.1
-
111
-
-
23444437213
-
Convection-enhanced delivery of macromolecules in the brain
-
Bobo RH, Laske DW, Akbasak A, Morrison PF, Dedrick RL, Oldfield EH. Convection-enhanced delivery of macromolecules in the brain. Proc Natl Acad Sci U S A. 1994;91(6):2076-2080.
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, Issue.6
, pp. 2076-2080
-
-
Bobo, R.H.1
Laske, D.W.2
Akbasak, A.3
Morrison, P.F.4
Dedrick, R.L.5
Oldfield, E.H.6
-
112
-
-
65349183290
-
Final results of phase I/II studies of IL 13-PE38QQR administered intratumorally (IT) and/or peritumorally (PT) via convection-enhanced delivery (CED) in patients undergoing tumor resection for recurrent malignant glioma
-
Orlando, USA, Abstract 1506
-
Prados M, Kunwar S, Lang FF, et al. Final results of phase I/II studies of IL 13-PE38QQR administered intratumorally (IT) and/or peritumorally (PT) via convection-enhanced delivery (CED) in patients undergoing tumor resection for recurrent malignant glioma. Proceedings of the American Society of Clinical Oncology Meeting. Orlando, USA. 2005. Abstract 1506.
-
(2005)
Proceedings of the American Society of Clinical Oncology Meeting
-
-
Prados, M.1
Kunwar, S.2
Lang, F.F.3
-
113
-
-
42249084323
-
Results from PRECISE: A randomized phase 3 study in patients with first recurrent glioblastoma multiformed (GBM) comparing cintredekin besudotox (CB) administered via convection-enhanced delivery (CED) with Gliadel wafers (GW)
-
Abstract MA-61
-
Kunwar S, Westphal M, Medhorn M, et al. Results from PRECISE: a randomized phase 3 study in patients with first recurrent glioblastoma multiformed (GBM) comparing cintredekin besudotox (CB) administered via convection-enhanced delivery (CED) with Gliadel wafers (GW). Neuro Oncol. 2007;9(4):467-602 Abstract MA-61.
-
(2007)
Neuro Oncol
, vol.9
, Issue.4
, pp. 467-602
-
-
Kunwar, S.1
Westphal, M.2
Medhorn, M.3
|