Trefoil factor family mRNA and protein expression in pterygium

International Journal of Oncology

Volumn 27, Issue 4, 2005, Pages 997-1003

  Lafontaine, Pierre Olivier ^a   Arnal, Murielle ^b   Buron, Nelly ^c   Solary, Eric ^c   Bron, Alain M ^a   Westley, Bruce R ^d   May, Felicity E B ^d   Bara, Jacques ^e   Gespach, Christian ^e   Creuzot Garcher, Catherine ^a  

^a DIJON UNIVERSITY HOSPITAL   (France)

^b CENTRE GEORGES FRANÇOIS LECLERC   (France)

^c UNIVERSITÉ DE BOURGOGNE   (France)

^d NEWCASTLE UNIVERSITY   (United Kingdom)

^e HÔPITAL SAINT ANTOINE   (France)

Author keywords

Conjunctiva; Goblet cells; Immuno histochemistry; MUC5AC; RT PCR; TFF1

Indexed keywords

COMPLEMENTARY DNA; MESSENGER RNA; MUCIN; MUCIN 5AC; PEPTIDE; TFF1 PROTEIN, HUMAN; TFF3 PROTEIN, HUMAN; TREFOIL FACTOR; TUMOR SUPPRESSOR PROTEIN;

ADULT; AGED; ARTICLE; BIOPSY; BIOSYNTHESIS; CHEMISTRY; CONJUNCTIVA; GENE EXPRESSION REGULATION; GOBLET CELL; HUMAN; IMMUNOHISTOCHEMISTRY; INFLAMMATION; METABOLISM; MIDDLE AGED; MUCOSA; PATHOLOGY; PTERYGIUM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TEMPERATURE; TIME;

ADULT; AGED; BIOPSY; CONJUNCTIVA; DNA, COMPLEMENTARY; GENE EXPRESSION REGULATION; GOBLET CELLS; HUMANS; IMMUNOHISTOCHEMISTRY; INFLAMMATION; MIDDLE AGED; MUCINS; MUCOUS MEMBRANE; PEPTIDES; PTERYGIUM; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION; TEMPERATURE; TIME FACTORS; TUMOR SUPPRESSOR PROTEINS;

EID: 33644818716     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.27.4.997     Document Type: Article

References (38)

1. Wright NA, Hoffmann W, Otto WR, Rio MC and Thim L: Rolling in the clover: trefoil factor family (TFF)-domain peptides, cell migration and cancer. FEBS Lett 408: 121-123, 1997.
2. Thim L: A new family of growth factor-like peptides. 'Trefoil' disulphide loop structures as a common feature in breast cancer associated peptide (pS2), pancreatic spasmolytic polypeptide (PSP), and frog skin peptides (spasmolysins). FEBS Lett 250: 85-90, 1989.
3. Emami S, Rodrigues S, Rodrigue CM, et al: Trefoil factor family (TFF) peptides and cancer progression. Peptides 25: 885-898,2004.
4. Bossenmeyer-Pourie C, Kannan R, Ribieras S, et al: The trefoil factor 1 participates in gastrointestinal cell differentiation by delaying G1-S phase transition and reducing apoptosis. J Cell Biol 157:761-770,2002.
5. Tomasetto C, Masson R, Linares JL, et al: pS2/TFFl interacts directly with the VWFC cysteine-rich domains of mucins. Gastroenterology 118: 70-80, 2000.
6. Ruchaud-Sparagano MH, Westley BR and May FE: The trefoil protein TFF1 is bound to MUC5AC in human gastric mucosa. Cell Mol Life Sci 61: 1946-1954, 2004.
7. Thim L, Madsen F and Poulsen SS: Effect of trefoil factors on the viscoelastic properties of mucus gels. Eur J Clin Invest 32: 519-527,2002.
8. Langer G, Jagla W, Behrens-Baumann W, Walter S and Hoffmann W: Secretory peptides TFF1 and TFF3 synthesized in human conjunctival goblet cells. Invest Ophthalmol Vis Sci 40: 2220-2224, 1999.
9. Kwok LS and Coroneo MT: A model for pterygium formation. Cornea 13: 219-224, 1994.
10. Kawano K, Uehara F and Ohba N: Lectin-cytochemical study on epithelial mucus glycoprotein of conjunctiva and pterygium. Exp Eye Res 47: 43-51, 1988.
11. Creuzot-Garcher C, Guerzider V, Assem M, Bron AM, Delannoy P and Bara J: Alteration of sialyl Lewis epitope expression in pterygium. Invest Ophthalmol Vis Sci 40: 1631-1636,1999.
12. Lafontaine PO, Arnal M, Buron N, et at Etude des peptides en trèfle dans le pterygion. J Fr Ophtalmol 26: 1007-1014, 2003.
13. Chomczynski P and Sacchi N: Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Annal Biochem 162: 156-159, 1987.
14. May FE, Church ST, Major S and Westley BR: The closely related estrogen-regulated trefoil proteins TFF1 and TFF3 have markedly different hydrodynamic properties, overall charge, and distribution of surface charge. Biochemistry 42: 8250-8259, 2003.
15. Muskett FW, May FE, Westley BR and Feeney J: Solution structure of the disulfide-linked dimer of human intestinal trefoil factor (TFF3): the intermolecular orientation and interactions are markedly different from those of other dimeric trefoil proteins. Biochemistry 42: 15139-15147, 2003.
16. Bara J, Chastre E, Mahiou I, et at Gastric Ml mucin, an early oncofetal marker of colon carcinogenesis, is encoded by the MUC5AC gene. Int J Cancer 75: 767-773, 1998.
17. Kindon H, Pothoulakis C, Thim L, Lynch-Devaney K and Podolsky DK: Trefoil peptide protection of intestinal epithelial barrier function: cooperative interaction with mucin glycoprotein. Gastroenterology 109: 516-523, 1995.
18. Dignass A, Lynch-Devaney K, Kindon H, Thim L and Podolsky DK: Trefoil peptides promote epithelial migration through a transforming growth factor beta-independent pathway. J Clin Invest 94: 376-383, 1994.
19. Playford RI, Marchbank T, Chinery R, et al: Human spasmolytic polypeptide is a cytoprotective agent that stimulates cell migration. Gastroenterology 108: 108-116, 1995.
20. Taupin DR, Kinoshita K and Podolsky DK: Intestinal trefoil factor confers colonic epithelial resistance to apoptosis. Proc Natl Acad Sci USA 97: 799-804, 2000.
21. Podolsky DK: Mechanisms of regulatory peptide action in the gastrointestinal tract: trefoil peptides. J Gastroenterol 35: 69-74, 2000.
22. Langer G, Jagla W, Behrens-Baumann W, Walter S and Hoffmann W: Ocular TFF-peptides: new mucus-associated secretory products of conjunctival goblet cells. Adv Exp Med Biol 506: 313-316, 2002.
23. Tan DT, Tang WY, Liu YP, Goh HS and Smith DR: Apoptosis and apoptosis related gene expression in normal conjunctiva and pterygium. Br J Ophthalmol 84: 212-216, 2000.
24. Dushku N, Hatcher SL, Albert DM and Reid TW: p53 expression and relation to human papillomavirus infection in Pingueculae, pterygia, and limbal tumors. Arch Ophthalmol 117:1593-1599,1999.
25. Dushku N and Reid TW: P53 expression in altered limbal basal cells of Pingueculae, pterygia, and limbal tumors. Curr Eye Res 16:1179-1192,1997.
26. Wang IJ, Lai WT, Liou SW, et at Impression cytology of pterygium. J Ocul Pharmacol Ther 16: 519-528, 2000.
27. Jagla W, Wiede A and Hoffmann W: Localization of TFF3 peptide to porcine conjunctival goblet cells. Cell Tissue Res 296: 525-530, 1999.
28. Steven P, Schafer G, Nolle B, Hinz M, Hoffmann W and Paulsen F: Distribution of TFF peptides in corneal disease and pterygium. Peptides 25: 819-825, 2004.
29. Garraway IP, Seligson D, Said J, Horvath S and Reiter RE: Trefoil factor 3 is overexpressed in human prostate cancer. Prostate 61: 209-214, 2004.
30. Saitoh T, Mochizuki T, Suda T, et al: Elevation of TFF1 gene expression during healing of gastric ulcer at non-ulcerated sites in the stomach: semiquantification using the single tube method of polymerase chain reaction. J Gastroenterol Hepatol 15: 604-609, 2000.
31. Rio MC, Chenard MP, Wolf C, et at. Induction of pS2 and hSP genes as markers of mucosal ulceration of the digestive tract. Gastroenterology 100: 375-379, 1991.
32. Gouyer V, Wiede A, Buisine MP, et al: Specific secretion of gel-forming mucins and TFF peptides in HT-29 cells of mucinsecreting phenotype. Biochim Biophys Acta 1539: 71-84, 2001.
33. Argueso P, Balaram M, Spurr-Michaud S, Keutmann HT, Dana MR and Gipson IK: Decreased levels of the goblet cell mucin MUC5AC in tears of patients with Sjogren syndrome. Invest Ophthalmol Vis Sci 43: 1004-1011, 2002.
34. Wright NA, Poulsom R, Stamp G, et ah Trefoil peptide gene expression in gastrointestinal epithelial cells in inflammatory bowel disease. Gastroenterology 104: 12-20, 1993.
35. Longman RJ, Douthwaite J, Sylvester PA, et at Coordinated localisation of mucins and trefoil peptides in the ulcer associated cell lineage and the gastrointestinal mucosa. Gut 47: 792-800, 2000.
36. Argueso P and Gipson IK: Epithelial mucins of the ocular surface: structure, biosynthesis and function. Exp Eye Res 73: 281-289,2001.
37. Xia HH, Yang Y, Lam SK, et at Aberrant epithelial expression of trefoil family factor 2 and mucin 6 in Helicobacter pylori infected gastric antrum, incisura, and body and its association with antralisation. J Clin Pathol 57: 861-866, 2004.
38. Rivat C, Rodrigues S, Bruyneel E, et at Implication of STAT3 signaling in human colonic cancer cells during Intestinal trefoil factor (TFF3) and VEGF-mediated cellular invasion and tumor growth. Cancer Res 65: 195-202, 2005.