Renal allograft thrombosis

Nephrology Dialysis Transplantation

Volumn 24, Issue 5, 2009, Pages 1388-1393

  Ponticelli, Claudio ^a   Moia, Marco ^b   Montagnino, Giuseppe ^b  

^a ISTITUTO AUXOLOGICO ITALIANO   (Italy)

^b FONDAZIONE IRCCS CA GRANDA OSPEDALE MAGGIORE POLICLINICO   (Italy)

Author keywords

Arterial thrombosis; Renal transplantation; Venous thrombosis

Indexed keywords

ACETYLSALICYLIC ACID; ALTEPLASE; BLOOD CLOTTING FACTOR 5; BLOOD CLOTTING FACTOR 5 LEIDEN; HEPARIN; METHYLPREDNISOLONE; OKT 3; PROTEIN C; PROTEIN S; STREPTOKINASE; UROKINASE;

ALGORITHM; ANTICOAGULANT THERAPY; ANTIPHOSPHOLIPID SYNDROME; CONTINUOUS INFUSION; DRUG MEGADOSE; GRAFT SURVIVAL; HUMAN; HYPERCOAGULABILITY; KIDNEY ALLOGRAFT THROMBOSIS; KIDNEY FAILURE; KIDNEY TRANSPLANTATION; KIDNEY VEIN THROMBOSIS; LOW DRUG DOSE; PATHOPHYSIOLOGY; POSTOPERATIVE COMPLICATION; PRIORITY JOURNAL; PROGNOSIS; RENAL ARTERY THROMBOSIS; REVIEW; RISK FACTOR; RISK REDUCTION; THROMBECTOMY; THROMBOPHILIA; THROMBOSIS; THROMBUS ASPIRATION;

AGE FACTORS; GRAFT REJECTION; HUMANS; KIDNEY TRANSPLANTATION; PROGNOSIS; RISK FACTORS; THROMBOSIS; TRANSPLANTATION, HOMOLOGOUS;

EID: 65249187237     PISSN: 09310509     EISSN: 14602385     Source Type: Journal    
DOI: 10.1093/ndt/gfp003     Document Type: Review

References (75)

1. Irish A. Renal allograft thrombosis: can thrombophilia explain the inexplicable? Nephrol Dial Transplant 1999; 14: 2297-2303
2. Smith JM, Stablein D, Singh A et al. Decreased risk of renal allograft thrombosis associated with interleukin-2 receptor antagonists: a report of the NAPRTCS. Am J Transplant 2006; 6: 585-588
3. Balachandra S, Tejani A. Recurrent vascular thrombosis in an adolescent transplant recipient. J Am Soc Nephrol 1997; 8: 1477-1481
4. Dodhia N, Rodby RA, Jensik SC et al. Renal transplant arterial thrombosis association with cyclosporine. Am J Kidney Dis 1991; 17: 532- 536
5. Sanni A, Wilson CH, Wyrley-Birch H et al. Donor risk factors for renal graft thrombosis. Transplant Proc 2007; 3: 138-139
6. Singh A, Stablein D, Tejani A. Risk factors for vascular thrombosis in pediatric renal transplantation: a special report of the North American Pediatric Renal Transplant Cooperative Study. Transplantation 1997; 63: 1263-1267
7. Smyth GP, Eng MP, Power RP et al. Long-term outcome of cadaveric pediatric en bloc transplantation. A 15 year experience. Transplant Proc 2005; 37: 4228-4229
8. Laube GF, Kellenberger CJ, Kemper MJ et al. Transplantation of infant enbloc kidneys into paediatric recipients. Pediatr Nephrol 2006; 21: 408-412
9. Englesbe MJ, Punch JD, Armstrong DR et al. Single-center study of technical graft loss in 714 consecutive renal transplants. Transplantation 2004; 78: 623-626
10. Luna E, Cubero JJ, Hernandez Gallego R et al. Evolution of sub-optimal renal transplantations: experience of a single Spanish center. Transplant Proc 2006; 38: 2394-2395
11. Lozano M, Oppenheimer F, Cofan F et al. Platelet procoagulant activity induced in vivo by muromonab-CD3 infusion in uremic patients. Thromb Res 2001; 104: 405-411
12. Shankar R, Bastani B, Salinas-Madrigal L et al. Acute thrombosis of the renal transplant artery after a single dose of OKT3. Am J Nephrol 2001; 21: 141-144
13. Abramowicz D, Pradier O, De Pauw L et al. High-dose glucocorticos-teroids increase the procoagulant effects of OKT3. Kidney Int 1994; 46: 1596-1602
14. Abramowicz D, De Pauw LE, Le Moine et al. Prevention of OKT3 nephrotoxicity after kidney transplantation. Kidney Int 1996; 49: S39- S43
15. Friedman GS, Meier-Kriesche HU, Kaplan B et al. Hypercoagulable states in renal transplant candidates: impact of anticoagulation upon incidence of renal allograft thrombosis. Transplantation 2001; 72: 1073-1078
16. Hara T, Naito K. Inherited antithrombin deficiency and end stage renal disease. Med Sci Monit 2005; 11: RA346-354
17. Heidenreich S, Dercken C, August C et al. High rateofacute rejections in renal allograft recipients with thrombophilic risk factors. J Am Soc Nephrol 1998; 9: 1309-1313
18. Heidenreich S, Juncker K, Wolters H et al. Outcome of kidney transplantation in patients with inherited thrombophilia: data of a prospective study. J Am Soc Nephrol 2003; 14: 234-239
19. Wuthrich RP, Cicvara-Muzar S, Booy C et al. Heterozygosity for the factor V Leiden (G1691A) mutation predisposes renal transplant recipients to thrombotic complications and graft loss. Transplantation 2001; 72: 549-550
20. Andrassy J, Zeier M, Andrassy K. Do we need screening for throm-bophilia prior to kidney transplantation? Nephrol Dial Transplant 2004; 19(Suppl 4): 64-68
21. Alakulppi NS, Kyllönen LE, Partanen J et al. Lack of association between thrombosis-associated and cytokine candidate gene polymorphisms and acute rejection or vascular complications after kidney transplantation. Nephrol Dial Transplant 2008; 23: 364-368
22. Meyer M, Laux G, Scherer S et al. No association of Factor V Leiden, Prothrombin G20210A, and MTHFR C677T gene polymorphisms with kidney allograft survival: a multicenter study. Transplantation 2007; 83: 1055-1058
23. Pherwani AD, Winter PC, McNamee PT et al. Is screening for factor V leiden and prothrombin G20210A mutations in renal transplantation worthwhile? Results of a large single-center UK study. Transplantation 2003; 76: 603-605
24. Vaidya S, Sellers R, Kimball P et al. Frequency, potential risk and therapeutic intervention in end-stage renal disease patients with an-tiphospholipid antibody syndrome: a multicenter study. Transplantation 2000; 69: 1348-1352
25. Verpooten GA, Cools FJ, Van Der Planken MG et al. Elevated plasminogen activator inhibitor levels in cyclosporin-treated renal allograft recipients. Nephrol Dial Transplant 1996; 11: 347- 351
26. Opatrny K Jr, Zemanova P, Opatrna S et al. Fibrinolysis in chronic renal failure, dialysis and renal transplantation. Ann Transplant 2002; 7: 34-43
27. Murphy BG, Hill CM, Middleton D et al. Increased renal allograft thrombosis in CAPD patients. Nephrol Dial Transplant 1994; 9: 1165- 1169
28. Snyder JJ, Kasiske BL, Gilbertson T et al. A comparison of transplant outcomes in peritoneal and hemodialysis patients. Kidney Int 2002; 62: 1423-1430
29. Vats AN, Donaldson L, Fine RN et al. Pretransplant dialysis status and outcome of renal transplantation in North American Children: a NAPRTCS Study. North American Pediatric Renal Transplant Cooperative Study. Transplantation 2000; 69: 1414-1419
30. Palomar R, Morales P, Rodrigo E et al. Venous graft thrombosis in patients on peritoneal dialysis before transplantation. Transplant Proc 2007; 39: 2128-2133
31. Penny MJ, Nankivell BJ, Disney APS et al. Renal graft thrombosis. Transplantation 1994; 58: 565-569
32. Bakir N, Sluiter WJ, Ploeg RJ et al. Primary renal graft thrombosis. Nephrol Dial Transplant 1996; 11: 140-147
33. Ettenger RB, Marik J, Grimm P. The impact of recombinant human eythropoietin therapy on renal transplantation. Kidney Int 1991; 18(4 suppl 1): 57-61
34. Muirhead N. Erythropoietin and renal transplantation. Kidney Int 1999; 69: S86-92
35. Lijfering WM, de Vries AP, Veeger NJ et al. Possible contribution of cytomegalovirus infection to the high risk of (recurrent) venous thrombosis after renal transplantation. Thromb Haemost 2008; 99: 127-132
36. Kamel MH, Mohan P, Conlon PJ et al. Rabbit antithymocyte globulin related decrease in platelet count reduced risk of pediatric renal transplant graft thrombosis. Pediatr Transplant 2006; 10: 816-821
37. Humar A, Matas AJ. Surgical complications after kidney transplantation. Semin Dial 2005; 18: 505-510
38. Schwenger V, Hinkel UP, Nahm AM et al. Color doppler ultrasonog-raphy in the diagnostic evaluation of renal allografts. Nephron Clin Pract 2006; 104: c107-112
39. Gao J, Ng A, Shih G et al. Intrarenal color duplex ultrasonography: a window to vascular complications of renal transplants. qJ Ultrasound Med 2007; 26: 1403-1418
40. Humar A, Key N, Ramcharan T et al. Kidney retransplants after initial graft loss to vascular thrombosis. Clin Transplant 2001; 15: 6-10
41. McIntyre JA, Wagenknecht DR. Antiphospholipid antibodies and renal transplantation: a risk assessment. Lupus 2003; 12: 555-559
42. Alkhumaizi AM, Olyaei AJ, Barry JM et al. Efficacy and safety of low molecular weight heparin in renal transplantation.Transplantation 1998; 66: 533-534
43. Nagra A, Trompeter RS, Fernando ON et al. The effect of heparin on graft thrombosis in pediatric renal allografts. Pediatr Nephrol 2004; 19: 531-535
44. Irish A. Hypercoagulability in renal transplant recipients. Identifying patients at risk of renal allograft thrombosis and evaluating strategies for prevention. Am J Cardiovasc Drugs 2004; 4: 139-149
45. Seeberger AO, Tibell A, Tyden G. Renal transplantation in r-HuEPO-treated patients. Transpl Int 1992; 5(Suppl 1): S104-106
46. Robertson AJ, Nargund V, Gray DW et al. Low dose aspirin as prophylaxis against renal-vein thrombosis in renal-transplant recipients. Nephrol Dial Transplant 2000; 15: 1865-1868
47. Stechman MJ, Charlwood N, Gray DW et al. Administration of 75 mg of aspirin daily for 28 days is sufficient prophylaxis against renal transplant vein thrombosis. Phlebology 2007; 22: 83-85
48. Kranz B, Vester U, Nadalin S et al. Outcome after kidney transplantation in children with thrombotic risk factors. Pediatr Transplant 2006; 7: 768-772
49. Grotz W, Siebig S, Olschewski M et al. Low-dose aspirin therapy is associated with improved allpograft function and prolonged allograft survival after kidney transplantation. Transplantation 2004; 77: 1848- 1853
50. Murphy JG, Taha R, Windmill DC et al. Influence of aspirin on early allograft thrombosis and chronic allograft nephropathy following renal transplantation. Br J Surg 2001; 88: 261-266
51. Hackstein H, Morelli AE, Larregina AT et al. Aspirin inhibits in vitro maturation and in vivo immunostimulatory function of murine myeloid dendritic cells. J Immunol 2001; 166: 7053-7062
52. Rouviere O, Berger P, Beziat C et al. Acute thrombosis of renal transplant artery: graft salvage by means of intra-arterial fibrinolysis. Transplantation 2002; 73: 403-409
53. Rerolle JP, Antoine C, Raynaud A et al. Successful endoluminal thrombo-aspirationofrenalgraft venous thrombosis. Transpl Int 2000; 13: 82-86
54. Mickelson JJ, MacNeily AE, Leblanc J et al. Renal transplantation in children 15 kg or less: the British Columbia Children's Hospital experience. J Urol 2006; 176: 1797-800
55. SubramaniamM, EdwardsR,Osman HY. Revascularization of kidney allograft after renal artery occlusion secondary to angioplasty. Prog Transplant 2007; 17: 177-179
56. McCarthy JM, Yeung CK, Keown PA. Late renal-artery thrombosis after transplantation associated with intraoperative abdominopelvic compression. N Engl J Med 1990; 323: 1845
57. Kiykim AA, Ozer C, Yildiz A et al. Development of transplant renal artery thrombosis and signs of haemolytic-uraemic syndrome following the change from cyclosporin to tacrolimus in a renal transplant patient. Nephrol Dial Transplant 2004; 19: 2653-2656
58. Karassa FB, Avdikou K, Pappas P et al. Late renal transplant arterial thrombosis in a patient with systemic lupus erythematosus and antiphospholipid syndrome. Nephrol Dial Transplant 1999; 14: 472- 474
59. Gritsch HA, Danovitch GM, Wilkinson A. Kidney transplantation. In: Hakim NS and Danovitch GM (eds). Transplantation Surgery, Vo l. 1. London: Springer, 2000, 135-144
60. Ramirez PJ, Gohn RY, Kestin A et al. Renal allograft loss due to proximal extension ofileofemoral deep venous thrombosis. Clin Transplant 2002; 16: 310-313
61. Abbott KC, Cruess DF, Agodoa LY et al. Early renal insufficiency and late venous thromboembolism after renal transplantation in the United States. Am J Kidney Dis 2004; 43: 120-130
62. Schwarz A, Krause PH, Offermann G et al. Impact of de novo membranous glomerulonephritis on the clinical course after kidney transplantation. Transplantation 1994; 58: 650-654
63. Schwieger J, Reiss R, Cohen JL et al. Acute renal allograft dysfunction in the setting of deep venous thrombosis: a case of successful urokinase thrombolysis and a review of the literature. Am J Kidney Dis 1993; 2: 345-350
64. Kim JK, Han DJ, Cho KS. Post-infectious diffuse venous stenosis after renal transplantation: duplex ultrasonography and CT angiography. Eur Radiol 2002; 12(Suppl 3): S118-S120
65. Wheeler MA, Taylor CM, Williams M et al. Factor V Leiden: a risk factor for renal vein thrombosis in renal transplantation. Pediatr Nephrol 2000; 14: 525-526
66. Giustacchini P, Pisanti F, Citterio F et al. Renal vein thrombosis after renal transplantation: an important cause of graft loss. Transplant Proc 2002; 34: 2126-2127
67. Chiu AS, Landsberg DN. Successful treatment of acute transplant renal vein thrombosis with selective streptokinase infusions. Transplant Proc 1991; 23: 2297-2300
68. Bedani PL, Galeotti R, Mugnani G et al. Successful local arterial urokinase infusion to reverse late postoperative venous thrombosis of a renal graft. Nephrol Dial Transplant 1999; 14: 2225-2227
69. Ortega Herrera R, Medina Benitez A, Hernandez Abad MJ. Renal vein partial thrombosis in 3 recipients of kidney transplantation. Arch Esp Urol 2000; 53: 45-48
70. Melamed ML, Kim HS, Jaar BG et al. Combined percutaneous mechanical and chemical thrombectomy for renal vein thrombosis in kidney transplant recipients. Am J. Transplant 2005; 5: 621- 626
71. Irish AB, Green FR, Gray DW et al. The factor V Leiden (R506Q) mutation and risk of thrombosis in renal transplant recipients. Transplantation 1997; 64: 604-607
72. Fischereder M, Gohring P, Schneeberger H et al. Early loss of renal transplants in patients with thrombophilia. Transplantation 1998; 65(7): 936-939
73. Ekberg H, Svensson PJ, Simanaitis M et al. Factor V R506Q mutation (activated protein C resistance) is an additional risk factor for early renal graft loss associated with acute vascular rejection. Transplantation 2000; 69(8): 1577-1581
74. Fischereder M, Schneeberger H, Lohse P et al. Increased rate of renal transplant failure in patients with the G20210A mutation of the prothrombin gene. Am J Kidney Dis 2001; 38(5): 1061-1064
75. Alakulppi NS, Kyllonen LE, Partanen J et al. Lack of association between thrombosis-associated and cytokine candidate gene polymorphism and acute rejection or vascular complications after kidney transplantation. Nephrol Dial Transplant 2008; 23: 364- 368