Increased rate of renal transplant failure in patients with the G20210A mutation of the prothrombin gene

American Journal of Kidney Diseases

Volumn 38, Issue 5, 2001, Pages 1061-1064

  Fischereder, Michael ^a,b   Schneeberger, Helmut ^a   Lohse, Peter ^a   Krämer, Bernhard K ^a   Schlöndorff, Detlef ^a   Land, Walter ^a  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^b UNIVERSITY HOSPITAL REGENSBURG   (Germany)

Author keywords

G20210A prothrombin gene mutation; Graft survival; Renal transplantation; Thrombophilia

Indexed keywords

PROTEIN C; PROTHROMBIN;

ADULT; ALLELE; ANTICOAGULATION; ARTICLE; FEMALE; GENE AMPLIFICATION; GENE MUTATION; GENETIC RISK; GRAFT FAILURE; HETEROZYGOSITY; HUMAN; KIDNEY TRANSPLANTATION; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; POSTOPERATIVE COMPLICATION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; RISK FACTOR; THROMBOGENESIS; THROMBOPHILIA;

EID: 0034750264     PISSN: 02726386     EISSN: None     Source Type: Journal    
DOI: 10.1053/ajkd.2001.28602     Document Type: Article

References (16)

1. Survival of nationally shared, HLA-matched kidney transplants from cadaveric donors
2. Early loss of renal transplants in patients with thrombophilia
3. High rate of acute rejections in renal allograft recipients with thrombophilic risk factors
4. Factor V R506Q mutation (activated protein C resistance) is an additional risk factor for early renal graft loss associated with acute vascular rejection
5. A common genetic variation in the 3′-untranslated region of the prothrombin gene is associated with elevated plasma prothrombin levels and an increase in venous thrombosis
6. Risk of venous thromboembolism associated with a G to A transition at position 20210 in the 3′-untranslated region of the prothrombin gene
7. Prothrombin G20210A mutant genotype is a risk factor for cerebrovascular ischemic disease in young patients
8. Heterozygous prothrombin gene mutation: A new risk factor for early renal allograft thrombosis
9. Renal transplant arterial thrombosis: Association with cyclosporine
10. The risk of recurrent deep venous thrombosis among heterozygous carriers of both factor V Leiden and the G20210A prothrombin mutation
11. Coincidence of factor V Leiden mutation and a mutation in the prothrombin gene at position 20210 in a patient with puerperal cerebral venous thrombosis
12. Prevalence of 20210 A allele of the prothrombin gene in venous thromboembolism patients
13. Prevalence of prothrombin G20210A, factor V G 1691A (Leiden), and methylenetetrahydrofolate reductase (MTHFR) C677T in seven different populations determined by multiplex allele-specific PCR
14. The factor V Leiden (R506Q) mutation and risk of thrombosis in renal transplant recipients
15. Female gender and resistance to activated protein C (FV:Q506) as potential risk factors for thrombosis after elective hip arthroplasty
16. Low-molecular-weight heparin combined with aspirin in pregnant women with thrombophilia and a history of preeclampsia or fetal growth restriction: A preliminary study